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Data Status: June 2018

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,788,033
Unique chemicals 12,829
Unique genes 46,096
Unique organisms 583
Phenotype–based interactions (curated) 181,582
Unique chemicals 6,798
Unique genes 1,913
Unique GO terms 4,248
Unique anatomical terms 794
Unique organisms 232
Gene–disease associations 24,119,408
Curated[1] 37,529
Unique genes 8,317
Unique diseases 5,791
Inferred[2] 24,081,879
Unique genes 45,133
Unique diseases 3,143
Chemical–disease associations 2,481,378
Curated[1] 211,540
Unique chemicals 9,521
Unique diseases 3,189
Inferred[2] 2,269,838
Unique chemicals 12,579
Unique diseases 5,778
Chemical–GO associations (enriched) 5,141,580
Chemical–pathway associations (enriched) 1,172,300
Disease–pathway associations (inferred) 282,471
Gene–gene interactions 499,892
Gene–GO annotations 1,212,701
Gene–pathway annotations 135,804
GO–disease associations (inferred) 935,447
Chemicals with curated data 15,630
Diseases with curated data 7,211
Via OMIM curation 4,173
Genes with curated data 46,166
Via OMIM curation 3,718
Curated references 129,237
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 121,491
Unique Chemicals 1,136
Unique Genes 432
Unique Diseases 419
Unique GO Terms 330
Curated Exposure References 2,121

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.161 release)
  2. ChemIDplus® (as of June 22, 2018)
  3. DrugBank (as of June 22, 2018)
  4. GO (as of June 22, 2018)
  5. KEGG (as of June 22, 2018)
  6. MeSH® (2018 MeSH release)
  7. NCBI Gene (as of June 22, 2018)
  8. NCBI Taxonomy (as of June 22, 2018)
  9. PubMed® (as of June 22, 2018)
  10. Reactome (as of June 22, 2018)