Skip navigation

Data Status: March 2019

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,898,228
Unique chemicals 13,108
Unique genes 47,581
Unique organisms 593
Phenotype–based interactions (curated) 189,578
Unique chemicals 7,183
Unique genes 2,072
Unique GO terms 4,725
Unique anatomical terms 821
Unique organisms 247
Gene–disease associations 25,439,779
Curated[1] 38,590
Unique genes 8,537
Unique diseases 5,779
Inferred[2] 25,401,189
Unique genes 47,213
Unique diseases 3,155
Chemical–disease associations 2,600,192
Curated[1] 214,390
Unique chemicals 9,657
Unique diseases 3,198
Inferred[2] 2,385,802
Unique chemicals 12,861
Unique diseases 5,767
Chemical–GO associations (enriched) 5,397,963
Chemical–pathway associations (enriched) 1,213,029
Disease–pathway associations (inferred) 286,191
Gene–gene interactions 557,985
Gene–GO annotations 1,217,323
Gene–pathway annotations 135,809
GO–disease associations (inferred) 2,111,009
Chemicals with curated data 15,891
Diseases with curated data 7,198
Via OMIM curation 4,132
Genes with curated data 47,651
Via OMIM curation 3,648
Curated references 131,381
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 132,827
Unique Chemicals 1,226
Unique Genes 467
Unique Diseases 431
Unique GO Terms 364
Curated Exposure References 2,337

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.5.170 release)
  2. ChemIDplus® (as of March 1, 2019)
  3. DrugBank (as of March 1, 2019)
  4. GO (as of March 1, 2019)
  5. KEGG (as of March 1, 2019)
  6. MeSH® (2019 MeSH release)
  7. NCBI Gene (as of March 1, 2019)
  8. NCBI Taxonomy (as of March 1, 2019)
  9. PubMed® (as of March 1, 2019)
  10. Reactome (as of March 1, 2019)