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Data Status: May 2018

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,773,245
Unique chemicals 12,766
Unique genes 45,921
Unique organisms 582
Phenotype–based interactions (curated) 176,398
Unique chemicals 6,696
Unique genes 1,897
Unique GO terms 4,119
Unique anatomical terms 780
Unique organisms 228
Gene–disease associations 23,930,247
Curated[1] 37,352
Unique genes 8,283
Unique diseases 5,744
Inferred[2] 23,892,895
Unique genes 44,965
Unique diseases 3,138
Chemical–disease associations 2,458,184
Curated[1] 210,814
Unique chemicals 9,495
Unique diseases 3,184
Inferred[2] 2,247,370
Unique chemicals 12,512
Unique diseases 5,731
Chemical–GO associations (enriched) 5,116,228
Chemical–pathway associations (enriched) 1,161,929
Disease–pathway associations (inferred) 281,149
Gene–gene interactions 490,444
Gene–GO annotations 1,209,108
Gene–pathway annotations 135,804
GO–disease associations (inferred) 932,397
Chemicals with curated data 15,571
Diseases with curated data 7,161
Via OMIM curation 4,114
Genes with curated data 45,990
Via OMIM curation 3,682
Curated references 128,721
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 115,897
Unique Chemicals 1,097
Unique Genes 404
Unique Diseases 399
Unique GO Terms 315
Curated Exposure References 2,020

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.160 release)
  2. ChemIDplus® (as of May 8, 2018)
  3. DrugBank (as of May 8, 2018)
  4. GO (as of May 8, 2018)
  5. KEGG (as of May 8, 2018)
  6. MeSH® (2018 MeSH release)
  7. NCBI Gene (as of May 8, 2018)
  8. NCBI Taxonomy (as of May 8, 2018)
  9. PubMed® (as of May 8, 2018)
  10. Reactome (as of May 8, 2018)