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Data Status: October 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,621,428
Unique chemicals 12,524
Unique genes 43,714
Unique organisms 572
Gene–disease associations 21,429,161
Curated[1] 35,539
Unique genes 7,895
Unique diseases 5,526
Inferred[2] 21,393,622
Unique genes 42,727
Unique diseases 3,111
Chemical–disease associations 2,336,715
Curated[1] 208,049
Unique chemicals 9,348
Unique diseases 3,158
Inferred[2] 2,128,666
Unique chemicals 12,271
Unique diseases 5,514
Chemical–GO associations (enriched) 5,030,126
Chemical–pathway associations (enriched) 1,119,270
Disease–pathway associations (inferred) 273,252
Gene–gene interactions 473,727
Gene–GO annotations 1,240,692
Gene–pathway annotations 135,814
GO–disease associations (inferred) 905,003
Chemicals with curated data 15,319
Diseases with curated data 6,944
Via OMIM curation 3,917
Genes with curated data 43,777
Via OMIM curation 3,546
Curated references 121,944
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 101,749
Unique Chemicals 975
Unique Genes 326
Unique Diseases 371
Unique GO Terms 282
Curated Exposure References 1,796

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.152 release)
  2. ChemIDplus® (as of September 29, 2017)
  3. DrugBank (as of September 29, 2017)
  4. GO (as of September 29, 2017)
  5. KEGG (as of September 29, 2017)
  6. MeSH® (2017 MeSH release)
  7. NCBI Gene (as of September 29, 2017)
  8. NCBI Taxonomy (as of September 29, 2017)
  9. PubMed® (as of September 29, 2017)
  10. Reactome (as of September 29, 2017)