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Data Status: August 2018

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,812,207
Unique chemicals 12,885
Unique genes 46,616
Unique organisms 583
Phenotype–based interactions (curated) 169,697
Unique chemicals 6,898
Unique genes 1,936
Unique GO terms 4,340
Unique anatomical terms 799
Unique organisms 234
Gene–disease associations 24,299,522
Curated[1] 37,782
Unique genes 8,371
Unique diseases 5,793
Inferred[2] 24,261,740
Unique genes 45,591
Unique diseases 3,147
Chemical–disease associations 2,507,429
Curated[1] 211,974
Unique chemicals 9,554
Unique diseases 3,191
Inferred[2] 2,295,455
Unique chemicals 12,635
Unique diseases 5,780
Chemical–GO associations (enriched) 5,180,064
Chemical–pathway associations (enriched) 1,179,283
Disease–pathway associations (inferred) 283,403
Gene–gene interactions 503,343
Gene–GO annotations 1,212,332
Gene–pathway annotations 135,805
GO–disease associations (inferred) 938,758
Chemicals with curated data 15,681
Diseases with curated data 7,212
Via OMIM curation 4,173
Genes with curated data 46,689
Via OMIM curation 3,728
Curated references 129,564
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 122,725
Unique Chemicals 1,155
Unique Genes 432
Unique Diseases 421
Unique GO Terms 332
Curated Exposure References 2,150

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.163 release)
  2. ChemIDplus® (as of August 8, 2018)
  3. DrugBank (as of August 8, 2018)
  4. GO (as of August 8, 2018)
  5. KEGG (as of August 8, 2018)
  6. MeSH® (2018 MeSH release)
  7. NCBI Gene (as of August 8, 2018)
  8. NCBI Taxonomy (as of August 8, 2018)
  9. PubMed® (as of August 8, 2018)
  10. Reactome (as of August 8, 2018)