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Data Status: February 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,529,578
Unique chemicals 12,137
Unique genes 42,522
Unique organisms 567
Gene–disease associations 20,168,862
Curated[1] 34,307
Unique genes 8,140
Unique diseases 5,005
Inferred[2] 20,134,555
Unique genes 41,533
Unique diseases 3,094
Chemical–disease associations 2,154,803
Curated[1] 204,631
Unique chemicals 9,183
Unique diseases 3,143
Inferred[2] 1,950,172
Unique chemicals 11,869
Unique diseases 4,325
Chemical–GO associations (enriched) 4,745,070
Chemical–pathway associations (enriched) 317,263
Disease–pathway associations (inferred) 60,815
Gene–gene interactions 383,850
Gene–GO annotations 1,195,260
Gene–pathway annotations 71,124
GO–disease associations (inferred) 822,176
Chemicals with curated data 14,975
Diseases with curated data 6,416
Via OMIM curation 3,379
Genes with curated data 43,537
Via OMIM curation 3,378
Curated references 119,720
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 88,205
Unique Chemicals 897
Unique Genes 289
Unique Diseases 321
Unique GO Terms 250
Curated Exposure References 1,524

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.144 release)
  2. ChemIDplus® (as of January 27, 2017)
  3. DrugBank (as of January 27, 2017)
  4. GO (as of January 27, 2017)
  5. KEGG (as of January 27, 2017)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of January 27, 2017)
  8. NCBI Taxonomy (as of January 27, 2017)
  9. PubMed® (as of January 27, 2017)
  10. Reactome (as of January 27, 2017)