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Data Status: July 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,604,856
Unique chemicals 12,373
Unique genes 43,639
Unique organisms 570
Gene–disease associations 21,281,609
Curated[1] 33,817
Unique genes 7,352
Unique diseases 4,400
Inferred[2] 21,247,792
Unique genes 42,646
Unique diseases 3,103
Chemical–disease associations 2,234,662
Curated[1] 207,006
Unique chemicals 9,300
Unique diseases 3,152
Inferred[2] 2,027,656
Unique chemicals 12,101
Unique diseases 4,387
Chemical–GO associations (enriched) 4,962,932
Chemical–pathway associations (enriched) 1,104,734
Disease–pathway associations (inferred) 257,283
Gene–gene interactions 467,680
Gene–GO annotations 1,225,236
Gene–pathway annotations 135,814
GO–disease associations (inferred) 852,710
Chemicals with curated data 15,201
Diseases with curated data 5,825
Via OMIM curation 2,729
Genes with curated data 43,701
Via OMIM curation 2,520
Curated references 121,266
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 95,302
Unique Chemicals 951
Unique Genes 317
Unique Diseases 357
Unique GO Terms 269
Curated Exposure References 1,694

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.150 release)
  2. ChemIDplus® (as of July 5, 2017)
  3. DrugBank (as of July 5, 2017)
  4. GO (as of July 5, 2017)
  5. KEGG (as of July 5, 2017)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of July 5, 2017)
  8. NCBI Taxonomy (as of July 5, 2017)
  9. PubMed® (as of July 5, 2017)
  10. Reactome (as of July 5, 2017)