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Data Status: December 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,650,118
Unique chemicals 12,580
Unique genes 43,939
Unique organisms 573
Gene–disease associations 21,684,551
Curated[1] 36,197
Unique genes 8,090
Unique diseases 5,714
Inferred[2] 21,648,354
Unique genes 42,958
Unique diseases 3,117
Chemical–disease associations 2,380,876
Curated[1] 209,048
Unique chemicals 9,389
Unique diseases 3,164
Inferred[2] 2,171,828
Unique chemicals 12,331
Unique diseases 5,700
Chemical–GO associations (enriched) 5,051,385
Chemical–pathway associations (enriched) 1,133,075
Disease–pathway associations (inferred) 276,872
Gene–gene interactions 478,977
Gene–GO annotations 1,246,927
Gene–pathway annotations 135,816
GO–disease associations (inferred) 920,678
Chemicals with curated data 15,381
Diseases with curated data 7,129
Via OMIM curation 4,104
Genes with curated data 44,010
Via OMIM curation 3,676
Curated references 122,580
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 108,100
Unique Chemicals 988
Unique Genes 337
Unique Diseases 377
Unique GO Terms 288
Curated Exposure References 1,884

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.155 release)
  2. ChemIDplus® (as of December 1, 2017)
  3. DrugBank (as of December 3, 2017)
  4. GO (as of December 1, 2017)
  5. KEGG (as of December 1, 2017)
  6. MeSH® (2018 MeSH release)
  7. NCBI Gene (as of December 1, 2017)
  8. NCBI Taxonomy (as of December 1, 2017)
  9. PubMed® (as of December 3, 2017)
  10. Reactome (as of December 1, 2017)