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Data Status: June 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,588,926
Unique chemicals 12,334
Unique genes 43,424
Unique organisms 570
Gene–disease associations 21,188,473
Curated[1] 33,733
Unique genes 7,326
Unique diseases 4,411
Inferred[2] 21,154,740
Unique genes 42,409
Unique diseases 3,103
Chemical–disease associations 2,221,687
Curated[1] 206,608
Unique chemicals 9,279
Unique diseases 3,152
Inferred[2] 2,015,079
Unique chemicals 12,061
Unique diseases 4,398
Chemical–GO associations (enriched) 4,966,069
Chemical–pathway associations (enriched) 324,863
Disease–pathway associations (inferred) 61,388
Gene–gene interactions 448,489
Gene–GO annotations 1,221,965
Gene–pathway annotations 71,153
GO–disease associations (inferred) 847,313
Chemicals with curated data 15,166
Diseases with curated data 5,839
Via OMIM curation 2,740
Genes with curated data 43,485
Via OMIM curation 2,518
Curated references 121,030
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 93,066
Unique Chemicals 945
Unique Genes 310
Unique Diseases 354
Unique GO Terms 265
Curated Exposure References 1,654

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.149 release)
  2. ChemIDplus® (as of June 5, 2017)
  3. DrugBank (as of June 5, 2017)
  4. GO (as of June 5, 2017)
  5. KEGG (as of June 5, 2017)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of June 5, 2017)
  8. NCBI Taxonomy (as of June 5, 2017)
  9. PubMed® (as of June 5, 2017)
  10. Reactome (as of June 5, 2017)