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Data Status

Contents

  1. New Data
  2. Curated Data Statistics
  3. Integrated Data

Top To top of page New Data

Our data was updated March 4, 2010, significantly for these chemicals, diseases and genes:

Amiodarone Azacitidine Benzo(a)pyrene Butyrates Chromium decitabine Depsipeptides icariin Phenol prochloraz Triiodothyronine triadimefon trichostatin A
Adenocarcinoma Atrial Fibrillation Breast Neoplasms Carcinoma, Hepatocellular Colorectal Neoplasms Glioma Leukemia, Myelogenous, Chronic, BCR-ABL Positive Leukemia, Myeloid, Acute Lipidoses Melanoma Carcinoma, Non-Small-Cell Lung Precursor Cell Lymphoblastic Leukemia-Lymphoma Prostatic Neoplasms
ABCB1 AHR CYP1A1 DNMT1 ESR1 GABBR1 GABBR2 KCNH2 ST1A8 SULT1A1 SULT1A3 THR

We're always adding new features, too.

Top To top of page Curated Data Statistics

CTD contains the following curated relationships from 19,069 references:

  Total Latest release
Chemical–gene interactions 222,945 1,826
Unique chemicals 5,511 242
Unique genes 17,256 569
Unique organisms 315 19
Unique references 16,189 246
Gene–disease relationships 792,296 18,786
Direct1 10,148 164
  Unique genes 4,700 126
  Unique diseases 3,616 56
Inferred2 782,148 18,622
  Unique genes 16,679 4,027
  Unique diseases 809 51
Chemical–disease relationships 220,387 3,885
Direct1 6,799 82
  Unique chemicals 1,690 35
  Unique diseases 825 51
Inferred2 213,588 3,803
  Unique chemicals 4,897 1,305
  Unique diseases 2,812 54
[1]
Direct relationships are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred relationships are established via CTD–curated chemical–gene interactions (e.g., Chemical A is associated with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a direct relationship with Disease B).

Top To top of page Integrated Data

CTD integrates the following external data:

Database Release Integration Date
ChemIDplus®   Mar 1, 2010
DrugBank   Mar 2, 2010
Gene Ontology Consortium   Mar 1, 2010
Kyoto Encyclopedia of Genes and Genomes   Mar 1, 2010
NCBI Gene   Mar 1, 2010
NCBI PubMed®   Mar 1, 2010
NCBI Taxonomy   Mar 1, 2010
NLM® Medical Subject Headings® 2010 MeSH  Mar 1, 2010
Reactome   Mar 1, 2010