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Data Status: May 2017

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,580,884
Unique chemicals 12,301
Unique genes 43,298
Unique organisms 570
Gene–disease associations 21,105,389
Curated[1] 34,646
Unique genes 8,194
Unique diseases 5,014
Inferred[2] 21,070,743
Unique genes 42,287
Unique diseases 3,101
Chemical–disease associations 2,208,460
Curated[1] 206,059
Unique chemicals 9,257
Unique diseases 3,150
Inferred[2] 2,002,401
Unique chemicals 12,030
Unique diseases 4,336
Chemical–GO associations (enriched) 4,935,405
Chemical–pathway associations (enriched) 323,207
Disease–pathway associations (inferred) 61,422
Gene–gene interactions 388,587
Gene–GO annotations 1,217,852
Gene–pathway annotations 71,205
GO–disease associations (inferred) 841,158
Chemicals with curated data 15,137
Diseases with curated data 6,421
Via OMIM curation 3,377
Genes with curated data 44,311
Via OMIM curation 3,376
Curated references 120,643
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 89,348
Unique Chemicals 938
Unique Genes 306
Unique Diseases 340
Unique GO Terms 264
Curated Exposure References 1,613

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.4.148 release)
  2. ChemIDplus® (as of May 5, 2017)
  3. DrugBank (as of May 5, 2017)
  4. GO (as of May 5, 2017)
  5. KEGG (as of May 5, 2017)
  6. MeSH® (2016 MeSH release)
  7. NCBI Gene (as of May 5, 2017)
  8. NCBI Taxonomy (as of May 4, 2017)
  9. PubMed® (as of May 5, 2017)
  10. Reactome (as of May 5, 2017)