Skip navigation

Data Status: January 2019

These statistics reflect our latest monthly data release.

Chemical–gene interactions (curated) 1,862,686
Unique chemicals 13,048
Unique genes 47,086
Unique organisms 590
Phenotype–based interactions (curated) 182,580
Unique chemicals 7,087
Unique genes 2,040
Unique GO terms 4,611
Unique anatomical terms 816
Unique organisms 242
Gene–disease associations 25,185,686
Curated[1] 38,129
Unique genes 8,415
Unique diseases 5,772
Inferred[2] 25,147,557
Unique genes 46,075
Unique diseases 3,153
Chemical–disease associations 2,562,327
Curated[1] 213,382
Unique chemicals 9,614
Unique diseases 3,196
Inferred[2] 2,348,945
Unique chemicals 12,797
Unique diseases 5,760
Chemical–GO associations (enriched) 5,336,484
Chemical–pathway associations (enriched) 1,201,646
Disease–pathway associations (inferred) 284,586
Gene–gene interactions 547,358
Gene–GO annotations 1,215,094
Gene–pathway annotations 135,809
GO–disease associations (inferred) 2,060,988
Chemicals with curated data 15,830
Diseases with curated data 7,193
Via OMIM curation 4,133
Genes with curated data 47,156
Via OMIM curation 3,655
Curated references 130,688
[1]
Curated associations are established by CTD (chemical–disease and gene–disease) and OMIM (gene–disease) curation.
[2]
Inferred associations are established via CTD-curated chemical–gene interactions (e.g., Chemical A is associated by inference with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).

Curated Exposure Statements 129,302
Unique Chemicals 1,186
Unique Genes 443
Unique Diseases 429
Unique GO Terms 359
Curated Exposure References 2,284

Integrated Data

In the current release, CTD data is integrated with data from these resources:

  1. BioGRID (3.5.168 release)
  2. ChemIDplus® (as of January 7, 2019)
  3. DrugBank (as of January 7, 2019)
  4. GO (as of January 7, 2019)
  5. KEGG (as of January 7, 2019)
  6. MeSH® (2019 MeSH release)
  7. NCBI Gene (as of January 7, 2019)
  8. NCBI Taxonomy (as of January 7, 2019)
  9. PubMed® (as of January 7, 2019)
  10. Reactome (as of January 7, 2019)