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Chemical mono-(2-ethylhexyl)phthalate

These are exposure studies associated with the chemical and all of its children.

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1–50 of 74 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Braun JM, et al. (2014). Health Outcomes and Measures of the Environment (HOME) | National Health and Nutrition Examination Survey (NHANES) We used a semi-Bayesian hierarchical regression model to estimate associations between prenatal blood or urine concentrations of 52 suspected endocrine disrupting chemicals and autistic behaviors at 4 and 5 years of age in a prospective birth cohort of 175 mothers and their children. socioeconomic status | tobacco 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Children | Pregnant females | Study subjects United States serum | urine 2,2',3,3',4,4',5-heptachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4',5-pentachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3,3',4,4'-pentachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,3',4,4'-tetrachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexabromobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2-ethyl-5-carboxypentyl phthalate | beta-hexachlorocyclohexane | bisphenol A | DDT | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | Hexachlorobenzene | hexadecafluoro-nonanoic acid | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | nonachlor | oxychlordane | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | phthalic acid | Polychlorinated Biphenyls Details Autism Spectrum Disorder
2. Robinson O, et al. (2015). INfancia y Medio Ambiente (INMA) Project In summary, the correlation analysis presented here of multiple environmental exposures among pregnant women provide a first picture of the structure of the exposome during the crucial in utero period. 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Pregnant females Spain air | blood, cord | colostrum | serum | urine | water 2,2',3,4,4',5',6-heptabromodiphenyl ether | 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Antimony | Arsenic | Benzene | beta-hexachlorocyclohexane | bisphenol A | Cadmium | Cesium | Chloroform | Cobalt | Copper | Cotinine | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Lead | Mercury | Molybdenum | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Nickel | Nitric Oxide | Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | PCB 180 | pentabrominated diphenyl ether 100 | pentabromodiphenyl ether | perfluorohexanesulfonic acid | perfluorononanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phthalic Acids | Selenium | Thallium | Tobacco Smoke Pollution | Trihalomethanes | Zinc Details
3. Agay-Shay K, et al. (2015). INfancia y Medio Ambiente (INMA) Project Prenatal exposure to organochlorines was positively associated with overweight at age 7 years in our study population. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | Arsenic | beta-hexachlorocyclohexane | bisphenol A | Cadmium | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Halogenated Diphenyl Ethers | Hexachlorobenzene | Lead | Mercury | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | PCB 180 | pentabrominated diphenyl ether 100 | Phthalic Acids Children | Pregnant females Spain blood, cord | serum | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5,5'-hexabrominated diphenyl ether | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-ethyl-5-carboxypentyl phthalate | Arsenic | beta-hexachlorocyclohexane | bisphenol A | Cadmium | decabromobiphenyl ether | Dichlorodiphenyl Dichloroethylene | Halogenated Diphenyl Ethers | Hexachlorobenzene | Lead | Mercury | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | PCB 180 | pentabrominated diphenyl ether 100 | Phthalic Acids Details Body Weight | Obesity | Prenatal Exposure Delayed Effects
4. Holmes AK, et al. (2014). Exposure to the parent compound of the phthalate metabolite MEHP may be associated with breast cancer. 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Hexachlorocyclohexane | Mirex | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | monomethyl phthalate | nonachlor | o,p'-DDT | oxychlordane | PCB 180 Controls for disease:Breast Neoplasms | Subjects with disease:Breast Neoplasms | Study subjects United States serum | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4'-tetrabromodiphenyl ether | 2,4,5,2',4',5'-hexachlorobiphenyl | beta-hexachlorocyclohexane | DDT | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | Hexachlorocyclohexane | Mirex | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | monomethyl phthalate | nonachlor | o,p'-DDT | oxychlordane | PCB 180 Details Breast Neoplasms
5. LaRocca J, et al. (2015). Harvard Epigenetic Birth Cohort (HEBC) These results suggest that prenatal phenol and phthalate exposure is associated with altered microRNA expression in placenta, suggesting a potential mechanism of endocrine-disrupting chemicals toxicity in humans. 2,4-dichlorophenol | 2,5-dichlorophenol | bisphenol A | butylbenzyl phthalate | butylparaben | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisodecyl phthalate | diisononyl phthalate | methylparaben | oxybenzone | Parabens | Phenols | Phthalic Acids | propylparaben | Triclosan Infants or newborns | Pregnant females United States placenta | urine 2,4-dichlorophenol | 2,5-dichlorophenol | 2-ethyl-5-carboxypentyl phthalate | bisphenol A | butylparaben | diisodecyl phthalate | diisononyl phthalate | methylparaben | MIR142 | MIR15A | MIR185 | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | oxybenzone | propylparaben | Triclosan Details regulation of gene silencing by miRNA
6. Ferguson KK, et al. (2014). Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) We explored the relationship of prenatal and childhood exposures to phthalates and bisphenol A with pubertal onset and sex hormones in boys (ages 8-14); prenatal exposure was associated with decreased dehydroepiandrosterone sulfate, decreased inhibin B, increased SHBG, greatly reduced odds of adrenarche, and slightly reduced odds of puberty, while childhood exposure was not associated with adrenarche or puberty, but some exposures were associated with increased SHBG levels and decreased testosterone levels. age | sex 2-ethyl-5-carboxypentyl phthalate | bisphenol A | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Phthalic Acids Children | Fetuses | Pregnant females Mexico serum | urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | Dehydroepiandrosterone Sulfate | INHBB | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | SHBG | Testosterone Details dehydroepiandrosterone secretion | development of secondary male sexual characteristics | inhibin secretion | testosterone secretion
7. Parada H JR, et al. (2018). Long Island Breast Cancer Study Project (LIBCSP) Consistent with laboratory evidence, we observed inverse associations between urinary concentrations of several phthalate metabolites and breast cancer (BC) and subsequent survival; however, these results should be interpreted with caution given that biospecimen collection among women with BC occurred after diagnosis, which may be of particular concern for our case-control findings. 2-ethyl-5-carboxypentyl phthalate | Diethylhexyl Phthalate | diisodecyl phthalate | diisononyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid | Phthalic Acids Controls for disease:Breast Neoplasms | Subjects with disease:Breast Neoplasms United States urine 2-ethyl-5-carboxypentyl phthalate | Diethylhexyl Phthalate | diisodecyl phthalate | diisononyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid | Phthalic Acids Details Breast Neoplasms
8. Specht IO, et al. (2015). INUENDO Our aim was to investigate time to pregnancy (TTP) according to serum levels of diethylhexyl phthalate (DEHP) and diisononyl phthalate (DiNP) metabolites in both partners. 2-ethyl-5-carboxypentyl phthalate | diisononyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monoisononylphthalate Pregnant females | Study subjects Greenland|Poland|
Ukraine
serum 2-ethyl-5-carboxypentyl phthalate | diisononyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monoisononylphthalate Details fertilization
9. Shapiro GD, et al. (2015). Maternal-Infant Research on Environmental Chemicals (MIREC) Study Our findings add to the growing body of evidence supporting the role of maternal arsenic exposure as a risk factor for gestational diabetes; however, no statistically significant associations were observed for phthalates, bisphenol A, or other metals. Arsenic | bisphenol A | Cadmium | Lead | Mercury | Phthalic Acids Subjects with disease:Diabetes, Gestational | Subjects with disease:Glucose Intolerance | Pregnant females Canada blood | urine Arsenic | bisphenol A | Cadmium | Lead | Mercury | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Details Diabetes, Gestational | Glucose Intolerance
10. Larsson K, et al. (2014). COnsortium to Perform Human biomonitoring on a European Scale (COPHES) | DEMOnstration of a study to COordinate and Perform Human biomonitoring on a European Scale (DEMOCOPHES) The objectives of the present study were to evaluate the levels of 10 phthalate metabolites, 5 parabens, bisphenol A and triclosan in urine from Swedish children (6-11 years old) and their mothers, in relation to demographics, lifestyle, housing and different potential sources of exposure to these chemicals. bisphenol A | butylbenzyl phthalate | butylparaben | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisononyl phthalate | ethyl-p-hydroxybenzoate | methylparaben | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | propylparaben | Triclosan Children | Mothers Sweden urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | butylparaben | Diethylhexyl Phthalate | diisononyl phthalate | ethyl-p-hydroxybenzoate | methylparaben | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | mono(carboxy-isooctyl)phthalate | monoethyl phthalate | propylparaben | Triclosan Details
11. Jukic AM, et al. (2016). National Health and Nutrition Examination Survey (NHANES) | North Carolina Early Pregnancy Study (EPS) We investigated these chemicals (certain phthalates and bisphenol A) in relation to follicular- and luteal-phase lengths, time to pregnancy, and early pregnancy loss (within 6 weeks of the last menstrual period) among women attempting pregnancy. bisphenol A | butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid Study subjects United States urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details Abortion, Spontaneous | luteinization | regulation of ovarian follicle development
12. Watkins DJ, et al. (2017). Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) Associations between in utero phthalate and bisphenol A exposure and peripubertal measures of male reproductive development are dependent on the timing of that exposure during gestation. age | sex bisphenol A | Dibutyl Phthalate | Diethylhexyl Phthalate | mono-benzyl phthalate | monoethyl phthalate | Phthalic Acids Children | Fetuses | Pregnant females Mexico serum | urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | Dehydroepiandrosterone Sulfate | Dibutyl Phthalate | Diethylhexyl Phthalate | Estradiol | INHBB | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | SHBG Details Prenatal Exposure Delayed Effects | dehydroepiandrosterone secretion | development of secondary male sexual characteristics | estradiol secretion | inhibin secretion
13. Cantonwine DE, et al. (2016). Urinary concentrations of BPA and several phthalate metabolites were significantly associated with increased risk of preeclampsia. sex bisphenol A | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid Pregnant females United States urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid Details Pre-Eclampsia
14. Casas M, et al. (2016). INfancia y Medio Ambiente (INMA) Project This study, one of the first to combine repeat exposure biomarker measurements and multiple growth measures during pregnancy, finds little evidence of associations of bisphenol A or phthalate exposures with fetal growth. bisphenol A | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Phthalic Acids Fetuses | Pregnant females Spain urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | Phthalic Acids Details Birth Weight | head development
15. Rudel RA, et al. (2011). In this study, geometric mean (GM) urinary bisphenol A (BPA) concentrations fell by 66% and GM bis(2-ethylhexyl) phthalate (DEHP) metabolite concentrations fell by 53-56% when participants began a 'fresh foods' diet, suggesting that most BPA and DEHP intake came from food packaging or meals outside the home. bisphenol A | Diethylhexyl Phthalate | Phthalic Acids Children | Study subjects United States urine bisphenol A | Creatinine | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | monomethyl phthalate Details
16. Ashley-Martin J, et al. (2014). Maternal-Infant Research on Environmental Chemicals (MIREC) Study The objective of the present study was to assess the association between prenatal exposure to phthalates and bisphenol A and fetal levels of adiponectin and leptin using data collected in the Maternal-Infant Research on Environmental Chemicals (MIREC) study, a multisite Canadian cohort study. sex bisphenol A | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | phthalic acid Infants or newborns | Pregnant females Canada urine bisphenol A | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | phthalic acid Details metabolic process
17. Lewis RC, et al. (2013). Early Life Exposure in Mexico to Environmental Toxicants (ELEMENT) In this study, we measured total concentrations of bisphenol A and nine phthalate metabolites in urine samples from children (8-13 years old) and their mothers (during third trimester), and demonstrate that personal care product use is associated with exposure to multiple phthalates in children. age bisphenol A | Phthalic Acids Children | Fetuses | Pregnant females Mexico urine 2-ethyl-5-carboxypentyl phthalate | bisphenol A | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details
18. Serrano SE, et al. (2014). National Health and Nutrition Examination Survey (NHANES) | The Infant Development and Environment Study (TIDES) This study examined the association between intake of specific foods and phthalate metabolite concentrations in a cohort of pregnant women. diet butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate Pregnant females | Study subjects United States urine 2-ethyl-5-carboxypentyl phthalate | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details
19. Soomro MH, et al. (2018). EDEN Occurrence of eczema in early childhood may be influenced by prenatal exposure to certain phthalates in boys. sex butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Children | Pregnant females France urine 2-ethyl-5-carboxypentyl phthalate | Dibutyl Phthalate | diisodecyl phthalate | diisononyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details Eczema
20. Joensen UN, et al. (2014). This study provides evidence that carriers of filaggrin gene loss-of-function alleles may have higher internal exposure to phthalates, possibly due to increased transepidermal absorption, and these carriers may indicate susceptible populations. genetics butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisononyl phthalate | Phthalic Acids Subjects with gene influence:FLG Denmark urine 2-ethyl-5-carboxypentyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monoisononylphthalate Details phthalate metabolic process
21. Jensen TK, et al. (2016). Odense Child Cohort In this prospective study among 245 mother-son pairs, no dose-response association between maternal phthalate exposure and anogenital distance or penile width in the male offspring was found. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | diisononyl phthalate | Phthalic Acids Infants or newborns | Pregnant females Denmark urine 2-ethyl-5-carboxypentyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diisononyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monoisononylphthalate Details anatomical structure development
22. Adibi JJ, et al. (2003). As part of the research being conducted by the Columbia Center for Children's Environmental Health, we have measured levels of phthalates in 48-hr personal air samples collected from parallel cohorts of pregnant women in New York, New York, (n = 30) and in Krakow, Poland (n = 30). butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Pregnant females Poland|United States air | urine butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Details
23. Valvi D, et al. (2015). INfancia y Medio Ambiente (INMA) Project This study suggests that prenatal phthalate exposure may be associated with postnatal growth and blood pressure in a sex-specific manner. age | sex butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | phthalic acid Children | Pregnant females Spain urine 2-ethyl-5-carboxypentyl phthalate | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid Details developmental growth | regulation of blood pressure
24. Jurewicz J, et al. (2013). Urinary phthalate metabolites levels were significantly associated with a decrease in sperm motility, testosterone level, and an increase sperm DNA damage and sperm aneuploidy. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisononyl phthalate Study subjects Poland urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | monoisononylphthalate Details Aneuploidy | negative regulation of flagellated sperm motility | negative regulation of testosterone biosynthetic process
25. Bornehag CG, et al. (2015). National Health and Nutrition Examination Survey (NHANES) | Study for Future Families (SFF) | Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA) Study We find that diisononyl phthalate is associated with a shorter anogenital distance in boys at the age of 21 months, which is of concern because AGD has been related to male genital birth defects and impaired reproductive function in adult males. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisononyl phthalate | Phthalic Acids Infants or newborns | Pregnant females | Study subjects Sweden|United States urine 2-ethyl-5-carboxypentyl phthalate | Creatinine | Diethylhexyl Phthalate | diisononyl phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Details Prenatal Exposure Delayed Effects | anatomical structure development
26. Hauser R, et al. (2006). The present study confirms previous results on the relationship of altered semen quality with exposure to monobutyl phthalate at general population levels. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | dimethyl phthalate Study subjects United States urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | monomethyl phthalate Details negative regulation of flagellated sperm motility | spermatogenesis
27. Koch HM, et al. (2013). Exposure to high molecular weight phthalates in this cohort appears to be driven by dietary intake, while non-dietary routes such as use of personal care products and ubiquitous sources including dust and indoor air appear to explain exposure to low molecular weight phthalates. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | dimethyl phthalate | Phthalic Acids Study subjects Germany urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monomethyl phthalate Details
28. Weuve J, et al. (2006). National Health and Nutrition Examination Survey (NHANES) Infants in neonatal intensive care units exposed to polyvinyl chloride plastic medical devices show detectable urinary concentrations of phthalate metabolites, and these indicies are related to the degree of intensiveness of product use. butylbenzyl phthalate | Dibutyl Phthalate | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate Children | Infants or newborns Germany|United States urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate Details
29. López-Carrillo L, et al. (2010). We show for the first time that exposure to diethyl phthalate, the parent compound of monoethyl phthalate, may be associated with increased risk of breast cancer, whereas exposure to the parent phthalates of monobenzyl phthalate and mono(3-carboxypropyl) phthalate might be negatively associated. butylbenzyl phthalate | Diethylhexyl Phthalate | diethyl phthalate | diisobutyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monobutyl phthalate | phthalic acid Controls for disease:Breast Neoplasms | Subjects with disease:Breast Neoplasms | Study subjects Mexico urine 2-ethyl-5-carboxypentyl phthalate | butylbenzyl phthalate | diethyl phthalate | diisobutyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monobutyl phthalate | phthalic acid Details Breast Neoplasms
30. Genuis SJ, et al. (2012). National Health and Nutrition Examination Survey (NHANES) Induced perspiration may be useful to facilitate elimination of some potentially toxic phthalate compounds including diethylhexyl phthalate and mono-(2-ethylhexyl)phthalate. Sweat analysis may be helpful in establishing the existence of accrued diethylhexyl phthalate in the human body. Dibutyl Phthalate | dicyclohexyl phthalate | Diethylhexyl Phthalate | diethyl phthalate Study subjects Canada|United States serum | sweat | urine Dibutyl Phthalate | Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details
31. Moreau M, et al. (2017). National Health and Nutrition Examination Survey (NHANES) Using exposure prediction tools, daily intakes of phthalates were estimated based on the urinary concentrations of their respective monoesters. Dibutyl Phthalate | Diethylhexyl Phthalate Study subjects United States urine Dibutyl Phthalate | Diethylhexyl Phthalate | mono-(2-ethylhexyl)phthalate | monobutyl phthalate Details
32. Wirth JJ, et al. (2008). Urinary concentrations of several phthalate metabolites were measured in men, and the results suggest that ambient phthalate metabolite concentrations may adversely affect human semen quality. Dibutyl Phthalate | Diethylhexyl Phthalate | diethyl phthalate | Phthalic Acids Study subjects United States urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monomethyl phthalate Details spermatogenesis
33. Schlumpf M, et al. (2010). We present data on chemicals in human milk of 54 mother/child pairs, where for the first time cosmetic UV filters (sunscreens), synthetic musks, parabens, and phthalate metabolites were analyzed in the same sample along with persistent organochlor pollutants, polybrominated diphenylethers, and polychlorinated biphenyls. diet Dibutyl Phthalate | Diethylhexyl Phthalate | diisobutyl phthalate | Parabens | Perfume | Pesticides | Polybrominated Biphenyls | Polychlorinated Biphenyls | Sunscreening Agents Infants or newborns | Mothers Switzerland milk, human 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4'-trichlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4,5,2',5'-pentachlorobiphenyl | 2,5,2',5'-tetrachlorobiphenyl | acetyl methyl tetramethyl tetralin | alpha-hexachlorocyclohexane | beta-hexachlorocyclohexane | Chlordan | chlorpyrifos-ethyl | DDT | Dichlorodiphenyl Dichloroethylene | Dieldrin | enzacamene | ethylhexyl methoxycinnamate | ethyl-p-hydroxybenzoate | galaxolide | Heptachlor | hexabrominated diphenyl ether 153 | hexabromodiphenyl ether 154 | Hexachlorobenzene | Hexachlorocyclohexane | homosalate | methylparaben | mono-(2-ethylhexyl)phthalate | monobutyl phthalate | mono-isobutyl phthalate | musk ketone | musk xylene | nonachlor | octocrylene | octyl dimethyl 4-aminobenzoic acid | o,p'-DDT | oxybenzone | oxychlordane | PCB 180 | pentabrominated diphenyl ether 100 | phantolid | Polychlorinated Biphenyls | propylparaben | Toxaphene | tribromodiphenyl ether 28 Details
34. Araki A, et al. (2014). Sapporo Cohort, Hokkaido Study on Environment and Child Health This study found that maternal di(2-ethylhexyl) phthalate exposure negatively correlates with the levels of P4, inhibin B, and INLS3 and these associations were more pronounced in male infants than in females. sex Diethylhexyl Phthalate Fetuses | Infants or newborns | Pregnant females Japan blood | blood, cord mono-(2-ethylhexyl)phthalate Details Leydig cell differentiation | negative regulation of prolactin secretion | regulation of inhibin secretion | regulation of progesterone biosynthetic process | Sertoli cell development
35. Latini G, et al. (2003). Our findings confirm the presence of detectable Diethylhexyl Phthalate/mono-(2-ethylhexyl)phthalate in most of the examined newborns at birth, observe phthalate serum concentrations in a wide population of human newborns, and suggest that phthalate exposure is significantly associated with a shorter pregnancy duration. Diethylhexyl Phthalate Infants or newborns Italy blood, cord Diethylhexyl Phthalate | mono-(2-ethylhexyl)phthalate Details Prenatal Exposure Delayed Effects
36. Kato K, et al. (2004). We evaluated mono-(2-ethylhexyl) phthalate and two oxidative metabolites, mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) and mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), as markers for exposure to DEHP in 127 paired human urine and serum samples. Diethylhexyl Phthalate Study subjects United States serum | urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate Details
37. Lu J, et al. (2014). We estimated the daily intake of di-2-ethylhexylphthalate (DEHP) among workers in flavoring factories in China by converting urinary levels of metabolites into DEHP intake levels using two pharmacokinetic models (for an exposed group and two control groups); no significant differences were found among the three groups of workers. Diethylhexyl Phthalate Workers China urine Diethylhexyl Phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate Details
38. Buckley JP, et al. (2016). Mount Sinai Children's Environmental Health Study | National Health and Nutrition Examination Survey (NHANES) Prenatal phthalate exposures were not associated with increased body fat among children 4-9 years of age, though high prenatal di(2-ethylhexyl) phthalate exposure may be associated with lower fat mass in childhood. Diethylhexyl Phthalate | diethyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid Children | Pregnant females | Study subjects United States urine 2-ethyl-5-carboxypentyl phthalate | diethyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | phthalic acid Details fat cell proliferation
39. Hauser R, et al. (2016). Environment and Reproductive Health (EARTH) Urinary concentrations of Diethylhexyl Phthalate metabolites were inversely associated with oocyte yield, clinical pregnancy, and live birth following assisted reproductive technologies. Diethylhexyl Phthalate | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Study subjects United States urine 2-ethyl-5-carboxypentyl phthalate | Diethylhexyl Phthalate | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details fertilization | oocyte maturation | reproduction
40. Zota AR, et al. (2014). National Health and Nutrition Examination Survey (NHANES) We observed pronounced changes in urinary concentrations of phthalate metabolites among the U.S. population between 2001 and 2010; urinary metabolite concentrations of DEP, DnBP, BBzP, and DEHP declined approximately 20-50%, whereas urinary metabolite concentrations of DiBP and DiNP increased by > 100%. Diethylhexyl Phthalate | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Study subjects United States urine 2-ethyl-5-carboxypentyl phthalate | Diethylhexyl Phthalate | diisodecyl phthalate | diisononyl phthalate | di-n-octyl phthalate | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details
41. Barr DB, et al. (2003). National Health and Nutrition Examination Survey (NHANES) We evaluated exposure to di-(2-ethylhexyl) phthalate in 62 persons, children and adults, by measuring mono-(2-ethylhexyl) phthalate, mono-(2-ethyl-5-oxohexyl) phthalate, and mono-(2-ethyl-5-hydroxyhexyl) phthalate in urine using an adaptation of our isotope dilution HPLC-tandem mass spectrometry method. Diethylhexyl Phthalate | phthalic acid Study subjects United States urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Details
42. Teitelbaum SL, et al. (2008). We evaluated intraindividual temporal variability in 19 urinary biomarkers of endocrine disrupters (eight phthalate metabolites from six phthalate diesters, six phytoestrogens, and five phenols) among New York City minority children. Endocrine Disruptors Children United States urine 2,3-bis(3'-hydroxybenzyl)butane-1,4-diol | 2,3-bis(3'-hydroxybenzyl)butyrolactone | 2,4-dichlorophenol | 2,5-dichlorophenol | 2-ethyl-5-carboxypentyl phthalate | 2-phenylphenol | bisphenol A | daidzein | Equol | Genistein | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monomethyl phthalate | O-desmethylangolensin | oxybenzone | Triclosan Details
43. La Rocca C, et al. (2014). Our study indicates the relevance of the living environment when investigating the exposure to endocrine disrupters and the modulation of nuclear receptors (as a suitable biomarker of the effect) to assess the endocrine disrupters impact on reproductive health. Endocrine Disruptors Controls for disease:Infertility, Female | Subjects with disease:Infertility, Female Italy blood | leukocyte, mononuclear | serum AHR | AR | bisphenol A | ESR1 | ESR2 | mono-(2-ethylhexyl)phthalate | NR1I2 | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
44. Ihde ES, et al. (2015). Endocrine disrupting environmental chemicals were detected in all children in the study, with measurable levels of 4-nonylphenol in nearly one third of subjects; this is the first known published study of 4-nonylphenol levels in American children; no associations were found between the urine levels of these chemicals tested and estrogen metabolites. Endocrine Disruptors Children United States urine 16-hydroxyestrone | 2-hydroxyestradiol | 2-hydroxyestrone | 2-methoxyestrone | 4-hydroxyestrone-4-methyl ether | 4-hydroxyestrone | 4-nonylphenol | bisphenol A | butylparaben | Estrogens | ethyl-p-hydroxybenzoate | methylparaben | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | monoethyl phthalate | propylparaben | Triclosan Details estrogen metabolic process
45. Lee WC, et al. (2017). Maternal-Infant Research on Environmental Chemicals (MIREC) Study We present an approach using factor analysis through principal component method and cluster analysis as an attempt to determine the pregnancy exposome; our results show the association between certain socio-demographic characteristics of the population of pregnant women and the presence of residual mixtures of common chemicals in their blood and urine. socioeconomic status Hydrocarbons, Fluorinated | Metals | Pesticides | Plasticizers | Polychlorinated Biphenyls Pregnant females Canada blood | plasma | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Arsenic | beta-hexachlorocyclohexane | bisphenol A | Cacodylic Acid | Cadmium | Dichlorodiphenyl Dichloroethylene | diethyl phosphate | dimethyl phosphate | Lead | Manganese | Mercury | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | nonachlor | O,O-dimethyl phosphorothionate | oxychlordane | PCB 180 | perfluorooctane sulfonic acid | perfluorooctanoic acid Details
46. Sexton K, et al. (2012). School Health Initiative Environment, Learning, and Disease (SHIELD) Biologic markers confirm that children from a low-income, ethnically diverse neighborhood experienced concurrent exposure to a variety of hazardous environmental chemicals during their everyday activities. socioeconomic status Metals, Heavy | Organothiophosphorus Compounds | Pesticides | Phthalic Acids | Polychlorinated Biphenyls | Tobacco Smoke Pollution | Volatile Organic Compounds Children United States blood | urine 2,2',3',4,4',5-hexachlorobiphenyl | 2,2',3,5,5',6-hexachlorobiphenyl | 2,3,3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,4',5-tetrachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | 2-xylene | beta-hexachlorocyclohexane | Cotinine | DDT | Dichlorodiphenyl Dichloroethylene | dimethyl phosphate | Lead | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | nonachlor | PCB 180 | Tetrachloroethylene | Toluene Details
47. Stahlhut RW, et al. (2007). National Health and Nutrition Examination Survey (NHANES) In this national cross-section of U.S. men, concentrations of several prevalent phthalate metabolites showed statistically significant correlations with abdominal obesity and insulin resistance. mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Study subjects United States mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate Details Insulin Resistance | Obesity
48. Weuve J, et al. (2010). National Health and Nutrition Examination Survey (NHANES) In this large nationally representative cross-sectional study, in which we used urinary phthalate metabolite concentrations as biomarkers of exposure to four parent phthalates, we observed weak positive associations for urinary monobutyl phthalate, and weak inverse associations for urinary mono(2-ethylhexyl) phthalate, in relation to self-reported history of endometriosis and leiomyomata. mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | phthalic acid Controls for disease:Endometriosis | Subjects with disease:Endometriosis | Controls for disease:Leiomyoma | Subjects with disease:Leiomyoma | Study subjects United States urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | phthalic acid Details Endometriosis | Leiomyoma
49. Machtinger R, et al. (2018). We sought to explore the association between maternal urinary phthalate metabolite concentrations and long non-coding RNAs expression in placenta to better understand potential mechanisms through which they participate in mediating phthalate toxicity. mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | mono-isobutyl phthalate | monomethyl phthalate | Phthalic Acids Infants or newborns | Pregnant females United States placenta | urine BACE1-AS | cyclohexane-1,2-dicarboxylic acid monohydroxy isononyl ester | DACT3-AS1 | DBH-AS1 | DPP10-AS1 | HOTTIP | IGF2-AS | LINC01159 | MALAT1 | MEG9 | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate | monoisononylphthalate | monomethyl phthalate | NCBP2-AS2 | NEAT1 | OIP5-AS1 | SLC44A3-AS1 | SOCS2-AS1 | SSSCA1-AS1 | TINCR | TUG1 | ZFAS1 Details ncRNA transcription
50. Factor-Litvak P, et al. (2014). Columbia Center for Children's Environmental Health (CCCEH) Maternal prenatal urinary metabolite concentrations measured in late pregnancy of di-n-butyl phthalate and di-isobutyl phthalate are associated with deficits in children's intellectual development at age 7 years. mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Children | Pregnant females United States urine mono(2-ethyl-5-hydroxyhexyl) phthalate | mono-(2-ethylhexyl)phthalate | mono-benzyl phthalate | monobutyl phthalate | monoethyl phthalate | mono-isobutyl phthalate Details cognition | learning or memory
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