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Chemical Fused-Ring Compounds

1–50 of 6,872 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 11-hydroxytestosterone androgen metabolic process Ketoconazole [Ketoconazole results in decreased androgen metabolic process] which results in decreased chemical synthesis of 11-hydroxytestosterone 1: Equus caballus Microsomes, Liver   1
2. 11-hydroxytestosterone androgen metabolic process Troleandomycin [Troleandomycin results in decreased androgen metabolic process] which results in decreased chemical synthesis of 11-hydroxytestosterone 1: Equus caballus Microsomes, Liver   1
3. 11-hydroxytestosterone androgen metabolic process Quercetin [Quercetin results in decreased androgen metabolic process] which results in decreased chemical synthesis of 11-hydroxytestosterone 1: Equus caballus Microsomes, Liver   1
4. 11-ketotestosterone locomotory behavior 11-ketotestosterone affects locomotory behavior 1: Danio rerio     1
5. 11-ketotestosterone androgen receptor signaling pathway 11-ketotestosterone results in increased androgen receptor signaling pathway 1: Gnathopogon caerulescens Sertoli Cells 1 gene: AR 1
6. 11-ketotestosterone androgen metabolic process bisphenol A [bisphenol A affects androgen metabolic process] which results in increased abundance of 11-ketotestosterone 1: Gobiocypris rarus Tissues 1 gene: ESR1 1
7. 1,24,25-trihydroxyvitamin D3 cell proliferation 1,24,25-trihydroxyvitamin D3 results in decreased cell proliferation 1: Homo sapiens Bone and Bones | Cells, Cultured   1
8. 1,24,25-trihydroxyvitamin D3 cell differentiation 1,24,25-trihydroxyvitamin D3 results in decreased cell differentiation 1: Rattus norvegicus Skull | Cells, Cultured   1
9. 1,24,25-trihydroxyvitamin D3 cell proliferation 1,24,25-trihydroxyvitamin D3 results in increased cell proliferation 1: Homo sapiens Bone and Bones | Cells, Cultured   1
10. 1,25,26-trihydroxyvitamin D3 cell proliferation 1,25,26-trihydroxyvitamin D3 results in increased cell proliferation 1: Homo sapiens Bone and Bones | Cells, Cultured   1
11. 1,25,26-trihydroxyvitamin D3 cell proliferation 1,25,26-trihydroxyvitamin D3 results in decreased cell proliferation 1: Homo sapiens Bone and Bones | Cells, Cultured   1
12. 1,25-dihydroxy-16-ene-vitamin D3 cell differentiation 1,25-dihydroxy-16-ene-vitamin D3 results in increased cell differentiation 1: Homo sapiens HL-60 Cells   1
13. 1,25-dihydroxy-16-ene-vitamin D3 cell cycle 1,25-dihydroxy-16-ene-vitamin D3 results in decreased cell cycle 1: Homo sapiens HL-60 Cells   1
14. 1,25-dihydroxy-16-ene-vitamin D3 cell proliferation 1,25-dihydroxy-16-ene-vitamin D3 results in decreased cell proliferation 1: Homo sapiens Prostate | Cell Line, Tumor   1
15. 1,25-dihydroxy-19-norvitamin D3 cell cycle 1,25-dihydroxy-19-norvitamin D3 analog affects cell cycle 1: Homo sapiens Plasma Cells   1
16. 1,25-dihydroxy-19-norvitamin D3 cell differentiation 1,25-dihydroxy-19-norvitamin D3 analog affects cell differentiation 1: Homo sapiens Plasma Cells   1
17. 1,25-dihydroxy-23-oxavitamin D3 response to oxidative stress 1,25-dihydroxy-23-oxavitamin D3 results in increased response to oxidative stress 1: Homo sapiens HL-60 Cells   1
18. 1,25-dihydroxy-23-thiavitamin D3 response to oxidative stress 1,25-dihydroxy-23-thiavitamin D3 results in increased response to oxidative stress 1: Homo sapiens HL-60 Cells   1
19. 1,25-dihydroxyergocalciferol positive regulation of myeloid leukocyte differentiation 1,25-dihydroxyergocalciferol results in increased positive regulation of myeloid leukocyte differentiation 1: Homo sapiens Myeloid Progenitor Cells | Cell Line, Tumor   1
20. 1,25-dihydroxyergocalciferol drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1,25-dihydroxyergocalciferol 1: Homo sapiens Keratinocytes | Cell Line   1
21. 1,25-dihydroxyvitamin D apoptotic process 1,25-dihydroxyvitamin D results in increased apoptotic process 1: Mus musculus Epithelial Cells | Cell Line, Tumor
6 genes: BAX | HRAS | IL17A | MAPK1 | MAPK3 | NR3C1
1
22. 1,25-dihydroxyvitamin D apoptotic process Dexamethasone Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in increased apoptotic process] 1: Mus musculus Epithelial Cells | Cell Line, Tumor
6 genes: BAX | HRAS | IL17A | MAPK1 | MAPK3 | NR3C1
1
23. 1,25-dihydroxyvitamin D vitamin D3 metabolic process Cholecalciferol [Cholecalciferol results in increased vitamin D3 metabolic process] which results in increased abundance of 1,25-dihydroxyvitamin D 1: Homo sapiens Serum   1
24. 1,25-dihydroxyvitamin D cell cycle Dexamethasone Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in decreased cell cycle] 1: Mus musculus Epithelial Cells | Cell Line, Tumor
6 genes: CDC25A | KMT5A | MAPK1 | MAPK3 | NR3C1 | TXNIP
1
25. 1,25-dihydroxyvitamin D apoptotic process Dexamethasone | MAPK1 [Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in decreased activity of MAPK1 protein]] which results in increased apoptotic process 1: Mus musculus Epithelial Cells | Cell Line, Tumor
6 genes: BAX | HRAS | IL17A | MAPK1 | MAPK3 | NR3C1
1
26. 1,25-dihydroxyvitamin D apoptotic process Dexamethasone | MAPK3 [Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in decreased activity of MAPK3 protein]] which results in increased apoptotic process 1: Mus musculus Epithelial Cells | Cell Line, Tumor
6 genes: BAX | HRAS | IL17A | MAPK1 | MAPK3 | NR3C1
1
27. 1,25-dihydroxyvitamin D cell cycle 1,25-dihydroxyvitamin D results in decreased cell cycle 1: Mus musculus Epithelial Cells | Cell Line, Tumor
6 genes: CDC25A | KMT5A | MAPK1 | MAPK3 | NR3C1 | TXNIP
1
28. 1,25-dihydroxyvitamin D cell proliferation Dexamethasone | MAPK3 [Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in decreased activity of MAPK3 protein]] which results in decreased cell proliferation 1: Mus musculus Epithelial Cells | Cell Line, Tumor
7 genes: BAX | CDC25A | HRAS | MXD1 | MYC | TXN | WNT3A
1
29. 1,25-dihydroxyvitamin D positive regulation of T-helper 17 type immune response 1,25-dihydroxyvitamin D results in increased positive regulation of T-helper 17 type immune response 1: Homo sapiens CD4-Positive T-Lymphocytes   1
30. 1,25-dihydroxyvitamin D cell proliferation Dexamethasone | MAPK1 [Dexamethasone promotes the reaction [1,25-dihydroxyvitamin D results in decreased activity of MAPK1 protein]] which results in decreased cell proliferation 1: Mus musculus Epithelial Cells | Cell Line, Tumor
7 genes: BAX | CDC25A | HRAS | MXD1 | MYC | TXN | WNT3A
1
31. 1,4,6-androstatrien-3,17-dione positive regulation of cytosolic calcium ion concentration 1,4,6-androstatrien-3,17-dione results in increased positive regulation of cytosolic calcium ion concentration 1: Homo sapiens Epidermis | Melanocytes | Cells, Cultured   1
32. 15-hydroxytestosterone androgen catabolic process Testosterone [Testosterone deficiency results in decreased androgen catabolic process] which results in decreased chemical synthesis of 15-hydroxytestosterone 1: Mus musculus Kidney   1
33. 15-hydroxytestosterone androgen metabolic process Dexamethasone [Dexamethasone results in increased androgen metabolic process] which results in increased chemical synthesis of 15-hydroxytestosterone 1: Oryctolagus cuniculus Lacrimal Apparatus   1
34. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione positive regulation of cytosolic calcium ion concentration Eugenol 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Eugenol results in increased positive regulation of cytosolic calcium ion concentration] 1: Homo sapiens Neuroglia | Cell Line, Tumor
11 genes: ADRA1A | AGT | EDN1 | EDNRB | IL1B | KNG1 | OXT | OXTR | TAC1 | TRPC6 | TRPV1
1
35. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway epigallocatechin gallate 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [epigallocatechin gallate results in increased positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway] 1: Homo sapiens Hepatocytes | Cell Line, Tumor
2 genes: EDN1 | PLCD1
1
36. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione calcium-mediated signaling Histamine 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Histamine results in increased calcium-mediated signaling] 1: Homo sapiens Osteoblasts
4 genes: EDN1 | EDNRB | PLCG1 | TNF
1
37. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione positive regulation of cytosolic calcium ion concentration resveratrol 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [resveratrol results in increased positive regulation of cytosolic calcium ion concentration] 1: Homo sapiens Mouth | Cell Line, Tumor
11 genes: ADRA1A | AGT | EDN1 | EDNRB | IL1B | KNG1 | OXT | OXTR | TAC1 | TRPC6 | TRPV1
1
38. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione release of sequestered calcium ion into cytosol alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine results in increased release of sequestered calcium ion into cytosol] 1: Homo sapiens Blood Platelets
2 genes: TRPA1 | TRPV1
1
39. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione release of sequestered calcium ion into cytosol TFLLRNPNDK-NH2 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [TFLLRNPNDK-NH2 results in increased release of sequestered calcium ion into cytosol] 1: Homo sapiens Blood Platelets
2 genes: TRPA1 | TRPV1
1
40. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione negative regulation of phospholipase C activity 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione affects negative regulation of phospholipase C activity 1: Homo sapiens Prostate | Cell Line, Tumor   1
41. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione calcium-mediated signaling Adenosine Triphosphate 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate results in increased calcium-mediated signaling] 1: Homo sapiens Thyroid Gland | Cell Line, Tumor
4 genes: EDN1 | EDNRB | PLCG1 | TNF
1
42. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione regulation of cytosolic calcium ion concentration bisphenol A 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [bisphenol A affects regulation of cytosolic calcium ion concentration] 1: Canis lupus familiaris Madin Darby Canine Kidney Cells
2 genes: F2 | PLCD1
1
43. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione calcium ion homeostasis Adenosine Triphosphate 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Adenosine Triphosphate affects calcium ion homeostasis] 1: Homo sapiens Brain | Cell Line, Tumor
2 genes: CASR | GNAS
1
44. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway 3,3',4,5'-tetrahydroxystilbene 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [3,3',4,5'-tetrahydroxystilbene results in increased positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway] 1: Homo sapiens Hepatocytes | Cell Line, Tumor
2 genes: EDN1 | PLCD1
1
45. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione calcium-mediated signaling Clodronic Acid 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Clodronic Acid results in increased calcium-mediated signaling] 1: Homo sapiens Thyroid Gland | Cell Line, Tumor
4 genes: EDN1 | EDNRB | PLCG1 | TNF
1
46. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione regulation of calcium ion transport Smoke 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Smoke analog affects regulation of calcium ion transport] 1: Homo sapiens Endothelial Cells | Cell Line
3 genes: AGT | CASR | RHOA
1
47. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione platelet aggregation TFLLRNPNDK-NH2 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [TFLLRNPNDK-NH2 results in increased platelet aggregation] 1: Homo sapiens Blood 1 gene: GNAS 1
48. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione apoptotic process Pilocarpine 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Pilocarpine results in increased apoptotic process] 1: Homo sapiens Skin | Fibroblasts
10 genes: ADRA1A | AKT1 | CASP3 | CASR | CCK | IL1B | MAPK1 | MAPK3 | PRKCA | TNF
1
49. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione calcium ion homeostasis Gallic Acid 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Gallic Acid affects calcium ion homeostasis] 1: Homo sapiens Brain | Cell Line, Tumor
2 genes: CASR | GNAS
1
50. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway resveratrol 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [resveratrol results in increased positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway] 1: Homo sapiens Hepatocytes | Cell Line, Tumor
2 genes: EDN1 | PLCD1
1
1–50 of 6,872 results.