Skip navigation

Chemical Irinotecan

Name Irinotecan
CAS Type 1 Name (1,4'-Bipiperidine)-1'-carboxylic acid, (4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester
Equivalent Terms 7 Ethyl 10 hydroxycamptothecin | 7-Ethyl-10-hydroxycamptothecin | Camptosar | Camptothecin 11 | Camptothecin-11 | CPT11 | CPT 11 | CPT-11 | Irinotecan Hydrochloride | Irrinotecan | NK012 Compound | SN 38 | SN-38 | SN3811 | SN 38 11 | SN-38-11
Definition A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.
Top Interacting
Genes
MeSH® ID D000077146
External Links

Top ↑ Ancestors

ChemicalsHeterocyclic Compounds Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Alkaloids Has associated genes Has associated diseases Has associated phenotype references Has associated exposure references Camptothecin Has associated genes Has associated diseases Has associated phenotype references Irinotecan Has associated genes Has associated diseases Has associated phenotype references

Top ↑ Descendants

None.