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Chemical Oxaliplatin

Name Oxaliplatin
CAS Type 1 Name Platinum(2+) ethanedioate (1R,2R)-1,2-cyclohexanediamine (1:1:1)
Equivalent Terms 1,2 Diaminocyclohexane Platinum Oxalate | 1,2-Diaminocyclohexane Platinum Oxalate | 1,2-Diamminocyclohexane(trans-1)oxolatoplatinum(II) | ACT078 | ACT 078 | ACT-078 | Cis-oxalato-(trans-l)-1,2-diaminocyclohexane-platinum(II) | Eloxatin | Eloxatine | L-OHP Cpd | Oxalato-(1,2-cyclohexanediamine)platinum II | Oxaliplatine | Oxaliplatin, (SP-4-2-(1R-trans))-isomer | Oxaliplatin, (SP-4-2-(1S-trans))-isomer | Oxaliplatin, (SP-4-3-(cis))-isomer | Platinum(II)-1,2-cyclohexanediamine Oxalate
Definition An organoplatinum complex in which the platinum atom is complexed with 1,2-diaminocyclohexane, and with an oxalate ligand which is displaced to yield active oxaliplatin derivatives. These derivatives form inter- and intra-strand DNA crosslinks that inhibit DNA replication and transcription. Oxaliplatin is an antineoplastic agent that is often administered with FLUOROURACIL and FOLINIC ACID in the treatment of metastatic COLORECTAL NEOPLASMS.
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Genes
MeSH® ID D000077150
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None.