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Chemical Benzazepines

1–50 of 407 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- histamine secretion mediated by immunoglobulin 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- results in increased histamine secretion mediated by immunoglobulin 1: Rattus norvegicus Hypothalamus, Posterior   1
2. 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- response to paraquat 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- results in decreased response to paraquat 1: Drosophila melanogaster Nervous System   1
3. 1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- cell death Dopamine | Methylmercury Compounds [1H-3-benzazepin-7-ol, 8-bromo-2,3,4,5-tetrahydro-3-methyl-5-phenyl- co-treated with Dopamine] inhibits the reaction [Methylmercury Compounds results in increased cell death] 1: Mus musculus Cerebral Cortex | Neurons | Cells, Cultured   1
4. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
5. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in increased abundance of 1-hydroxymethylmidazolam 1: Mus musculus Plasma 1 gene: CYP3A4 1
6. 1-hydroxymethylmidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
7. 1-hydroxymethylmidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
8. 1-hydroxymethylmidazolam drug metabolic process Rifampin [Rifampin results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
9. 1-hydroxymethylmidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
10. 1-hydroxymethylmidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
11. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
12. 1-hydroxymethylmidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
13. 1-hydroxymethylmidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
14. 1-hydroxymethylmidazolam drug metabolic process Glycerol [Glycerol results in decreased drug metabolic process] which results in decreased chemical synthesis of 1-hydroxymethylmidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
15. 1-hydroxymethylmidazolam drug metabolic process Thalidomide [Thalidomide results in increased drug metabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Homo sapiens Placenta | Cell Line, Tumor 1 gene: CYP3A4 1
16. 1-hydroxymethylmidazolam drug catabolic process Rifampin [Rifampin results in increased drug catabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Homo sapiens Hepatocytes | Cell Line, Tumor
2 genes: CYP3A4 | CYP3A5
1
17. 1-hydroxymethylmidazolam drug catabolic process Rifampin [Rifampin results in increased drug catabolic process] which results in increased chemical synthesis of 1-hydroxymethylmidazolam 1: Homo sapiens Hepatocytes | Cells, Cultured
2 genes: CYP3A4 | CYP3A5
1
18. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation LMO2 | TAL1 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide inhibits the reaction [[LMO2 protein co-treated with TAL1 protein] results in increased cell proliferation] 1: Mus musculus Blood | Cell Line, Tumor 1 gene: MYC 1
19. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide results in decreased cell proliferation 1: Homo sapiens Blood | Tumor Cells, Cultured 1 gene: MYC 1
20. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide results in decreased cell proliferation 1: Homo sapiens T-Lymphocytes | Cell Line, Tumor 1 gene: MYC 1
21. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation cyclopamine [cyclopamine co-treated with 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide] results in decreased cell proliferation 1: Homo sapiens T-Lymphocytes | Cell Line, Tumor 1 gene: MYC 1
22. 2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide cell proliferation Quercetin Quercetin promotes the reaction [2-(2-(3,5-difluorophenyl)-acetylamino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo(e)(1,4)diazepin-3-yl)propionamide results in decreased cell proliferation] 1: Homo sapiens T-Lymphocytes | Cell Line, Tumor 1 gene: MYC 1
23. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine excitatory postsynaptic potential ADTN 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine affects the reaction [ADTN results in decreased excitatory postsynaptic potential] 1: Rattus norvegicus Nucleus Accumbens | Neurons, Afferent | Synapses
3 genes: DRD2 | GRIN1 | SNCA
1
24. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine excitatory postsynaptic potential ADTN | SCH 23390 SCH 23390 affects the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine affects the reaction [ADTN results in decreased excitatory postsynaptic potential]] 1: Rattus norvegicus Nucleus Accumbens | Neurons, Afferent | Synapses
3 genes: DRD2 | GRIN1 | SNCA
1
25. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine vasodilation 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased vasodilation 1: Rattus norvegicus Lung | Blood Vessels
2 genes: DRD1 | SOD2
1
26. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine positive regulation of urine volume 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased positive regulation of urine volume 1: Rattus norvegicus Kidney 1 gene: DRD2 1
27. 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine cell death methylmercuric chloride 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [methylmercuric chloride results in increased cell death] 1: Mus musculus Cerebral Cortex | Neurons | Cells, Cultured   1
28. 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide cell proliferation 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide results in decreased cell proliferation 1: Homo sapiens Blood | Cell Line, Tumor   1
29. 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide cell proliferation 2-(((3,5-difluorophenyl)acetyl)amino)-N-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)propanamide results in decreased cell proliferation 1: Homo sapiens Jurkat Cells   1
30. 4'-chlorodiazepam cell chemotaxis 4'-chlorodiazepam results in increased cell chemotaxis 1: Homo sapiens Monocytes | Cells, Cultured   1
31. 4'-chlorodiazepam cell chemotaxis PK 11195 PK 11195 inhibits the reaction [4'-chlorodiazepam results in increased cell chemotaxis] 1: Homo sapiens Monocytes | Cells, Cultured   1
32. 4'-chlorodiazepam response to oxidative stress 4'-chlorodiazepam results in increased response to oxidative stress 1: Canis lupus familiaris Neutrophils | Cells, Cultured   1
33. 4-hydroxymidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
34. 4-hydroxymidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 2: Homo sapiens | Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
35. 4-hydroxymidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxymidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
36. 4-hydroxymidazolam drug metabolic process Rifampin [Rifampin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Mus musculus Intestines | Microsomes 1 gene: CYP3A4 1
37. 4-hydroxymidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
38. 4-hydroxymidazolam drug metabolic process Dexamethasone [Dexamethasone results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
39. 4-hydroxymidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
40. 4-hydroxymidazolam drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
41. 4-hydroxymidazolam drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Intestines | Epithelial Cells | Microsomes 1 gene: CYP3A4 1
42. 4-hydroxymidazolam drug metabolic process Glycerol [Glycerol results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxymidazolam 1: Rattus norvegicus Microsomes, Liver 1 gene: CYP3A4 1
43. 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine chemical synaptic transmission 8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine affects chemical synaptic transmission 1: Rattus norvegicus Prefrontal Cortex | Pyramidal Cells 1 gene: HRH1 1
44. Alprazolam cell proliferation Amino Acids, Peptides, and Proteins Alprazolam inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation] 1: Mus musculus Spleen | T-Lymphocytes | Cells, Cultured   1
45. Alprazolam cell proliferation Amino Acids, Peptides, and Proteins | IL2 IL2 protein inhibits the reaction [Alprazolam inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation]] 1: Homo sapiens Spleen | T-Lymphocytes | Cells, Cultured   1
46. Alprazolam cell proliferation Amino Acids, Peptides, and Proteins | IL2RA IL2RA protein inhibits the reaction [Alprazolam inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation]] 1: Mus musculus Spleen | T-Lymphocytes | Cells, Cultured   1
47. Alprazolam regulation of blood pressure Alprazolam results in decreased regulation of blood pressure 1: Homo sapiens Cardiovascular System   3
48. Alprazolam response to oxidative stress Caffeine [Caffeine co-treated with Alprazolam] results in increased response to oxidative stress 1: Homo sapiens HeLa Cells   1
49. Alprazolam response to oxidative stress Caffeine [Alprazolam co-treated with Caffeine] results in increased response to oxidative stress 1: Homo sapiens Myeloid Cells | Cell Line, Tumor   1
50. Alprazolam apoptotic process Alprazolam results in increased apoptotic process 1: Homo sapiens HeLa Cells
2 genes: CASP3 | PARP1
1
1–50 of 407 results.