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Chemical Benzo(a)pyrene

1–50 of 379 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. benzo(a)pyrene-DNA adduct DNA damage response, detection of DNA damage 1-methylanthracene | Benzo(a)pyrene | fluoranthene [1-methylanthracene co-treated with fluoranthene] promotes the reaction [[Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] which results in increased abundance of benzo(a)pyrene-DNA adduct] 1: Mus musculus Pulmonary Alveoli | Cell Line   1
2. benzo(a)pyrene-DNA adduct DNA damage response, detection of DNA damage Benzo(a)pyrene [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] which results in increased abundance of benzo(a)pyrene-DNA adduct 1: Mus musculus Pulmonary Alveoli | Cell Line   1
3. Benzo(a)pyrene DNA methylation Benzo(a)pyrene affects DNA methylation 1: Danio rerio Embryo, Nonmammalian
25 genes: ATRX | BAZ2A | BMI1 | CTCF | DMAP1 | DNMT1 | DNMT3A | DNMT3AA | DNMT3AB | DNMT3B | DNMT3BA | DNMT3BB.1 | DNMT3BB.2 | DNMT3L | EHMT1 | EZH2 | FOS | GATAD2A | HELLS | HEMK1 | KMT2A | MGMT | MT2 | MTR | PPM1D
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4. Benzo(a)pyrene positive regulation of histone H4 acetylation Benzo(a)pyrene results in decreased positive regulation of histone H4 acetylation 1: Homo sapiens MCF-7 Cells
4 genes: ARRB1 | KAT7 | MUC1 | SMARCB1
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5. Benzo(a)pyrene cell proliferation thymoquinone [Benzo(a)pyrene co-treated with thymoquinone] results in decreased cell proliferation 1: Homo sapiens Lung | Epithelial Cells | Cell Line, Tumor
327 genes: ACE | ACHE | ADRA1B | ADRA1D | AKT1 | ALK | ALKBH3 | APPL2 | AR | AREG | ARHGEF1 | ASAH2 | ASCC3 | AURKB | AXIN2 | BAD | BAX | BCAR1 | BCAT1 | BCL2 | BCL2L1 | BIN1 | BMP4 | BOK | BOP1 | BRAT1 | BRCA2 | BST2 | BUB1 | BUB1B | BYSL | CBFA2T3 | CD160 | CD276 | CD34 | CD5 | CD70 | CD74 | CD81 | CDC14A | CDC16 | CDC25A | CDC25C | CDC27 | CDK1 | CDK4 | CDK5R1 | CDK5RAP3 | CDK9 | CDV3 | CENPF | CEP120 | CFB | CITED1 | CITED2 | CKLF | CKS1B | CKS2 | CLK1 | COL4A3BP | CREBBP | CREG1 | CSE1L | CSF1 | CSF1R | CSGALNACT1 | CSPG4 | CTNNB1 | CUL1 | CUL5 | CUZD1 | CXCL1 | CYP1A1 | CYR61 | DAB2 | DACH1 | DAZAP1 | DCTN2 | DDIT4 | DICER1 | DKC1 | DLG1 | DLGAP5 | DLX5 | DNPH1 | DTYMK | DUSP22 | E2F8 | E4F1 | ECD | EDNRA | EGFR | EIF4B | EMP1 | EMP2 | ENPEP | ENTPD5 | EPO | EPS15 | EPS8 | ERBB2 | ERCC1 | ERCC2 | EREG | ERG | ESRRB | EVI5 | FAM83D | FBXL7 | FER | FES | FGF1 | FGF13 | FGF16 | FGF18 | FGF2 | FOXC1 | FOXC2 | FPGS | FSCN1 | FURIN | GAS6 | GBX2 | GCG | GDNF | GFI1B | GH1 | GLUL | GMNC | GNL3 | GPX1 | GRPR | GSK3B | H3F3A | H3F3B | HDGF | HGF | HHEX | HLCS | HMGA2 | HOXB4 | HRAS | HTR1A | ID4 | IFNAR2 | IGF1 | IGFBP4 | IGSF8 | IL12B | IL15RA | IL18 | IL18RAP | IL1A | IL2RA | INSIG1 | INSL4 | IRF2 | IRS2 | ISG20 | ITGA2 | KDM1A | KHDRBS1 | KIF15 | KIF2C | KITLG | KLF10 | KRT16 | LAMA5 | LGI1 | LIG4 | LIPG | LRP1 | LY6E | LY86 | MAP2K1 | MAP3K11 | MAP3K2 | MAP3K20 | MAP4K1 | MAP7 | MAPRE2 | MAS1 | MATK | MCM10 | MCM7 | MDM4 | MELK | MET | MIA | MIF | MKI67 | MNAT1 | MORF4L1 | MOV10L1 | MRE11A | MT3 | MVP | MXD1 | MYB | MYC | MYH10 | NANOG | NASP | NBN | NCF1 | NEDD8 | NKX6-1 | NPY | NUDC | NUMB | NUPR1 | OCA2 | ORC1 | OSM | OTUD6B | PA2G4 | PAK4 | PCNA | PDAP1 | PDK1 | PDPN | PDS5B | PDXK | PDZK1 | PELO | PEMT | PES1 | PICALM | PIM1 | PIM2 | PLCE1 | PLK1 | POLA1 | PPARD | PRDX1 | PRKD1 | PRKDC | PRL | PSPHP1 | PTEN | PTGES3 | PTMA | PTPN6 | PURB | PURBB | RAF1 | RAP1B | RAPGEF3 | RASGRP4 | RBBP7 | RETNLB | RHBDF1 | ROS1 | RPL23A | RPL29 | RPS27 | RRN3 | SBDS | SCRIB | SDCBP2 | SERPINF1 | SHH | SIPA1 | SIX1 | SIX2 | SKI | SKP2 | SORL1 | SOX11 | SOX2 | SPHK2 | SRA1 | SRC | SRGAP2 | STAT3 | STAT4 | STIL | SYK | TACC1 | TACC3 | TBCK | TBX1 | TBX20 | TCF19 | TCF7L2 | TFDP1 | TGFB1 | TGFB2 | THOC6 | THPO | TNF | TNFRSF1B | TNFSF13B | TNFSF9 | TOP2A | TP53 | TP63 | TPT1 | TPX2 | TRAIP | TRP63 | TSPAN5 | TSPO | TXLNA | TXN | TXNRD1 | UBE2V2 | UBR5 | UCHL1 | UHRF1 | UHRF2 | USP13 | USP28 | USP8 | VEGFA | VEGFD | VPS25 | VPS36 | VTI1B | VTN | XRCC5 | YAP1 | YME1L1 | ZEB1 | ZFP36L1 | ZFP36L2 | ZPR1
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6. Benzo(a)pyrene positive regulation of cell proliferation BMP2 Benzo(a)pyrene inhibits the reaction [BMP2 protein results in increased positive regulation of cell proliferation] 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Stem Cells | Cell Line
426 genes: ACER2 | ACER3 | ADM | ADORA2B | ADRA1D | ADRA2A | ADRB2 | AGT | AGTR1A | AKIRIN2 | AKR1C18 | AKR1C2 | AKR1C3 | AKT1 | ALDH3A1 | ANP32B | APLN | AR | AREG | ARNT2 | ARRB1 | ATF3 | AVP | AVPR1A | BAMBI | BCL2 | BCL2L1 | BIRC5 | BIRC6 | BLOC1S2 | BMP4 | BMP6 | BTC | CAD | CALCRL | CALR | CAMP | CAPN1 | CARM1 | CASR | CAV3 | CCAR1 | CCK | CCND1 | CCND2 | CCND3 | CCPG1 | CD248 | CD47 | CD81 | CD86 | CDC123 | CDC20 | CDC25B | CDC7 | CDCA7L | CDK13 | CDK2 | CDK4 | CDKN1B | CEACAM6 | CEP131 | CGA | CIAO1 | CIB1 | CLCF1 | CLDN7 | CLEC11A | CLU | CNBP | CNOT6 | CNOT6L | COL18A1 | COPS9 | COX17 | CRH | CRIP2 | CSF1 | CSF1R | CSF2 | CSF3 | CST3 | CTGF | CTNNB1 | CTSH | CUL3 | CUL4A | CXCL10 | CXCL12 | CXCL5 | CXCR2 | CXCR3 | DDR2 | DERL2 | DKC1 | DLG1 | DLL1 | DMD | DNAJA2 | DPP4 | EDN1 | EDN2 | EDNRA | EDNRB | EFEMP1 | EFNB2 | EGF | EGFR | EGR4 | EIF4G1 | EIF5A | EMP2 | ENPP2 | EPCAM | EPGN | EPHA1 | EPO | EPOR | ERBB2 | EREG | ESM1 | ETS1 | F2 | F2R | FABP4 | FAM98B | FASLG | FER | FGF1 | FGF18 | FGF2 | FGF7 | FGF9 | FGFBP1 | FGFR1 | FGFR1OP | FGFR3 | FGFR4 | FLT1 | FLT3 | FLT4 | FN1 | FNTA | FNTB | FOLR2 | FOSL1 | FOXM1 | FSHB | FXN | FZR1 | GAB2 | GATA3 | GCNT2 | GDNF | GHRH | GKN1 | GLP1R | GPER1 | GREM1 | GRK5 | HAS2 | HBEGF | HCK | HCLS1 | HDAC1 | HDAC2 | HDAC4 | HES1 | HES5 | HGF | HIF1A | HILPDA | HIPK1 | HIPK2 | HLX | HMGA2 | HMGB1 | HMGCR | HMGN5 | HOXA3 | HRAS | HSF1 | HSF4 | HSP90AA1 | HTR1A | ID2 | ID3 | ID4 | IFNG | IGF1 | IGF1R | IGF2 | IHH | IL11 | IL11RA1 | IL15 | IL18 | IL1B | IL2 | IL21 | IL24 | IL34 | IL4 | IL5 | IL6 | IL6R | IL6RA | IL6ST | IL7 | IL7R | IL9 | INS2 | INSM1 | INSR | IRS1 | IRS2 | ISL1 | ITGAV | ITGB1 | JAK2 | JUN | KDM4C | KDR | KITL | KITLG | KLB | KLF5 | KMT2D | KRAS | LAMC2 | LEF1 | LGALS3 | LGMN | LIF | LIFR | LRP5 | LYN | MAB21L2 | MAPK1 | MAPK15 | MARCKSL1 | MARK4 | MAS1 | MATK | MDM2 | MDM4 | MECP2 | MED1 | MFGE8 | MIB1 | MIR141 | MLXIPL | MST1R | MTA3 | MVD | MYB | MYC | MYOCD | NACC2 | NAMPT | NANOG | NAP1L1 | NBN | NCOR1 | NDUFAF4 | NGF | NKX2-5 | NLGN2 | NMB | NOD2 | NODAL | NOG | NOLC1 | NOP2 | NOTCH1 | NOTCH2 | NOX1 | NPM1 | NPY | NTF3 | NTN1 | NTRK2 | NTRK3 | ODC1 | OPTN | OSM | OSMR | OSR2 | PAK1 | PAX2 | PBX1 | PDCD10 | PDGFA | PDGFB | PDGFC | PDGFRA | PDGFRB | PDX1 | PGF | PGGT1B | PGR | PHIP | PKHD1 | PLA2G1B | PLA2G4A | PLAC8 | PLAU | POU3F3 | PPARD | PRAMEF11 | PRAMEF12 | PRC1 | PRL | PRMT1 | PROX1 | PRTN3 | PTEN | PTGER4 | PTGFR | PTGS2 | PTH1R | PTHLH | PTK2 | PTK2B | PTN | PTPN6 | RAC2 | RAD51B | RARA | RARB | RARG | RASIP1 | RELA | RNF187 | ROMO1 | RPA1 | RPL23 | RPRD1B | RPS9 | RRM2 | RTKN2 | S100A13 | S1PR1 | S1PR2 | S1PR3 | SAPCD2 | SCX | SDCBP | SERTAD1 | SFRP1 | SFRP2 | SHC1 | SHC4 | SHH | SHMT2 | SLC25A33 | SLC25A5 | SMARCA4 | SMO | SOX11 | SOX4 | SOX9 | SP6 | SPHK1 | SPHK2 | SRPK2 | SSBP3 | STAT1 | STAT3 | STOX1 | STX3 | STX4A | SUZ12 | SYF2 | TBC1D8 | TBRG4 | TBX1 | TBX2 | TBX3 | TCIRG1 | TET1 | TFAP2B | TFF2 | TGFB1 | TGFB2 | TGFB3 | TGFBR1 | TGFBR2 | TGFBR3 | THBS1 | THPO | THRB | TIAL1 | TIAM1 | TIMP1 | TIPIN | TNC | TNF | TNFRSF11A | TNFSF13 | TNFSF13B | TNFSF4 | TNS3 | TPD52 | TRAF5 | TRPC5 | TRPM4 | TSC22D1 | TSHR | TSLP | TTK | UBE2A | VEGFA | VEGFC | VEGFD | VIP | WDR77 | WNT1 | WNT2 | WNT5A | WNT7A | WNT7B | WWTR1 | XBP1 | YAP1 | ZFP703
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7. Benzo(a)pyrene protein oxidation Benzo(a)pyrene results in increased protein oxidation 1: Mus musculus Liver
3 genes: APOA1 | GPX1 | SUMF1
1
8. Benzo(a)pyrene negative regulation of androgen receptor activity Dihydrotestosterone [Benzo(a)pyrene results in increased negative regulation of androgen receptor activity] which results in decreased susceptibility to Dihydrotestosterone 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: HEYL 1
9. Benzo(a)pyrene positive regulation of calcium-dependent ATPase activity Butylated Hydroxyanisole Butylated Hydroxyanisole inhibits the reaction [Benzo(a)pyrene results in decreased positive regulation of calcium-dependent ATPase activity] 1: Rattus norvegicus Hippocampus   1
10. Benzo(a)pyrene reactive oxygen species biosynthetic process Catechin Catechin inhibits the reaction [Benzo(a)pyrene results in increased reactive oxygen species biosynthetic process] 1: Mus musculus Fibroblasts | Cell Line, Transformed
2 genes: GBF1 | NOX4
1
11. Benzo(a)pyrene positive regulation of monocyte differentiation Calcitriol Benzo(a)pyrene promotes the reaction [Calcitriol results in increased positive regulation of monocyte differentiation] 1: Homo sapiens THP-1 Cells
9 genes: ACIN1 | CD4 | CD74 | CSF1 | CTNNBIP1 | DCSTAMP | IL34 | JUN | ZFP36L1
1
12. Benzo(a)pyrene cell proliferation caffeic acid phenethyl ester [Benzo(a)pyrene co-treated with caffeic acid phenethyl ester] results in decreased cell proliferation 1: Homo sapiens Lung | Epithelial Cells | Cell Line, Tumor
327 genes: ACE | ACHE | ADRA1B | ADRA1D | AKT1 | ALK | ALKBH3 | APPL2 | AR | AREG | ARHGEF1 | ASAH2 | ASCC3 | AURKB | AXIN2 | BAD | BAX | BCAR1 | BCAT1 | BCL2 | BCL2L1 | BIN1 | BMP4 | BOK | BOP1 | BRAT1 | BRCA2 | BST2 | BUB1 | BUB1B | BYSL | CBFA2T3 | CD160 | CD276 | CD34 | CD5 | CD70 | CD74 | CD81 | CDC14A | CDC16 | CDC25A | CDC25C | CDC27 | CDK1 | CDK4 | CDK5R1 | CDK5RAP3 | CDK9 | CDV3 | CENPF | CEP120 | CFB | CITED1 | CITED2 | CKLF | CKS1B | CKS2 | CLK1 | COL4A3BP | CREBBP | CREG1 | CSE1L | CSF1 | CSF1R | CSGALNACT1 | CSPG4 | CTNNB1 | CUL1 | CUL5 | CUZD1 | CXCL1 | CYP1A1 | CYR61 | DAB2 | DACH1 | DAZAP1 | DCTN2 | DDIT4 | DICER1 | DKC1 | DLG1 | DLGAP5 | DLX5 | DNPH1 | DTYMK | DUSP22 | E2F8 | E4F1 | ECD | EDNRA | EGFR | EIF4B | EMP1 | EMP2 | ENPEP | ENTPD5 | EPO | EPS15 | EPS8 | ERBB2 | ERCC1 | ERCC2 | EREG | ERG | ESRRB | EVI5 | FAM83D | FBXL7 | FER | FES | FGF1 | FGF13 | FGF16 | FGF18 | FGF2 | FOXC1 | FOXC2 | FPGS | FSCN1 | FURIN | GAS6 | GBX2 | GCG | GDNF | GFI1B | GH1 | GLUL | GMNC | GNL3 | GPX1 | GRPR | GSK3B | H3F3A | H3F3B | HDGF | HGF | HHEX | HLCS | HMGA2 | HOXB4 | HRAS | HTR1A | ID4 | IFNAR2 | IGF1 | IGFBP4 | IGSF8 | IL12B | IL15RA | IL18 | IL18RAP | IL1A | IL2RA | INSIG1 | INSL4 | IRF2 | IRS2 | ISG20 | ITGA2 | KDM1A | KHDRBS1 | KIF15 | KIF2C | KITLG | KLF10 | KRT16 | LAMA5 | LGI1 | LIG4 | LIPG | LRP1 | LY6E | LY86 | MAP2K1 | MAP3K11 | MAP3K2 | MAP3K20 | MAP4K1 | MAP7 | MAPRE2 | MAS1 | MATK | MCM10 | MCM7 | MDM4 | MELK | MET | MIA | MIF | MKI67 | MNAT1 | MORF4L1 | MOV10L1 | MRE11A | MT3 | MVP | MXD1 | MYB | MYC | MYH10 | NANOG | NASP | NBN | NCF1 | NEDD8 | NKX6-1 | NPY | NUDC | NUMB | NUPR1 | OCA2 | ORC1 | OSM | OTUD6B | PA2G4 | PAK4 | PCNA | PDAP1 | PDK1 | PDPN | PDS5B | PDXK | PDZK1 | PELO | PEMT | PES1 | PICALM | PIM1 | PIM2 | PLCE1 | PLK1 | POLA1 | PPARD | PRDX1 | PRKD1 | PRKDC | PRL | PSPHP1 | PTEN | PTGES3 | PTMA | PTPN6 | PURB | PURBB | RAF1 | RAP1B | RAPGEF3 | RASGRP4 | RBBP7 | RETNLB | RHBDF1 | ROS1 | RPL23A | RPL29 | RPS27 | RRN3 | SBDS | SCRIB | SDCBP2 | SERPINF1 | SHH | SIPA1 | SIX1 | SIX2 | SKI | SKP2 | SORL1 | SOX11 | SOX2 | SPHK2 | SRA1 | SRC | SRGAP2 | STAT3 | STAT4 | STIL | SYK | TACC1 | TACC3 | TBCK | TBX1 | TBX20 | TCF19 | TCF7L2 | TFDP1 | TGFB1 | TGFB2 | THOC6 | THPO | TNF | TNFRSF1B | TNFSF13B | TNFSF9 | TOP2A | TP53 | TP63 | TPT1 | TPX2 | TRAIP | TRP63 | TSPAN5 | TSPO | TXLNA | TXN | TXNRD1 | UBE2V2 | UBR5 | UCHL1 | UHRF1 | UHRF2 | USP13 | USP28 | USP8 | VEGFA | VEGFD | VPS25 | VPS36 | VTI1B | VTN | XRCC5 | YAP1 | YME1L1 | ZEB1 | ZFP36L1 | ZFP36L2 | ZPR1
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13. Benzo(a)pyrene positive regulation of BMP signaling pathway Benzo(a)pyrene results in increased positive regulation of BMP signaling pathway 1: Homo sapiens Mammary Glands, Human | Epithelial Cells | Stem Cells | Cell Line
31 genes: ACVR1 | ACVRL1 | B4GALT5 | BMP4 | BMPR2 | CRB2 | CYR61 | ENG | FBXL15 | GATA4 | GATA6 | GDF5 | HES1 | HES5 | KCP | KDR | LZTS2A | MSX2 | NEO1 | NOTCH1 | NOTCH2 | PELO | SFRP5 | SNW1 | SOX11 | SULF1 | TGFBR3 | TSC22D3 | TWSG1 | UBE2O | VSIR
1
14. Benzo(a)pyrene positive regulation of monocyte differentiation Calcitriol Benzo(a)pyrene promotes the reaction [Calcitriol results in increased positive regulation of monocyte differentiation] 1: Homo sapiens U937 Cells
9 genes: ACIN1 | CD4 | CD74 | CSF1 | CTNNBIP1 | DCSTAMP | IL34 | JUN | ZFP36L1
1
15. Benzo(a)pyrene lipid oxidation Malondialdehyde [Benzo(a)pyrene results in increased lipid oxidation] which results in increased abundance of Malondialdehyde 1: Rattus norvegicus Hippocampus 1 gene: PLA2G7 1
16. Benzo(a)pyrene cell death NFE2L2 NFE2L2 mutant form promotes the reaction [Benzo(a)pyrene results in increased cell death] 1: Homo sapiens Trophoblasts | Cell Line
35 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | CACNA1A | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | EMP3 | FAF1 | FOSL2 | GSDME | GZMM | HMOX1 | KLK8 | MAP3K10 | MAP3K11 | MAP3K20 | NDOR1 | NUP62 | OPTN | PARP4 | PMP22 | PNPLA8 | PRKD2 | PTGER3 | SNCAIP | SUSD6 | TGFB2 | TRAF6 | VAPA
1
17. Benzo(a)pyrene cell migration Benzo(a)pyrene results in increased cell migration 1: Mus musculus Mammary Glands, Animal | Cell Line, Tumor
159 genes: ABI2 | ABP1 | ACVR1 | ADAM9 | ADAMTS12 | ADGRE2 | ADGRG1 | ANG | ARC | ARHGAP35 | ARPC5 | ATN1 | BAMBI | BCAR1 | BRAT1 | BTG1 | CARMIL1 | CARMIL2 | CCDC88A | CD151 | CD248 | CD24A | CD2AP | CD44 | CD47 | CD63 | CDC42BPB | CDH2 | CDH7 | CDK1 | CEACAM1 | CELF1 | CLASP2 | CLN3 | COL5A1 | CORO1A | CORO1B | CORO7 | CSK | CTGF | CTHRC1 | CUL3 | CXCL12 | CXCR4 | DCHS1 | DGKZ | DOCK1 | EFNA1 | ELMO1 | ELMO2 | ELMO3 | EMP2 | ENG | ENPEP | EPHA2 | EPHA3 | EPHB3 | ERG | FAM83D | FAT1 | FERMT2 | FGFR1 | FGFR4 | FLT1 | FMNL3 | FN1 | FNDC3B | FOXC1 | FSCN1 | FUT8 | FZD2 | GAB2 | GAS6 | GFRA1 | GPC6 | GSK3A | GSK3B | HBEGF | HES1 | HOXA5 | IL12B | ITGA4 | ITGA7 | ITGAV | ITGB1 | ITGB1B | JAM3 | KDR | LAMA5 | LAMB1 | LAMC1 | LCP1 | MDK | MET | MMP14 | MMP2 | MYO18A | NANOS1 | NFATC2 | NODAL | NOX1 | NRP1 | NUP62 | PAFAH1B1 | PAK4 | PALLD | PARP9 | PDGFRA | PDGFRB | PDPK1 | PIK3CB | PIP5K1A | PLCG1 | PODXL | PPP1R9B | PRAG1 | PRPF40A | PSTPIP2 | PTEN | PTPRF | PTPRK | PVR | RAB1A | RELN | RHBDF1 | S1PR1 | SCRIB | SCYL3 | SEMA3AA | SH3BP1 | SH3KBP1 | SIRPA | SIX2 | SLC9A1 | SNAI1 | SNAI2 | SORL1 | SRC | SRGAP1 | SSTR4 | ST14 | STRIP2 | TGFB1 | TGFB2 | TGFBR2 | TGFBR3 | THBS1 | TIAM1 | TNFAIP1 | TNS3 | TREM1 | VAV2 | VAV3 | VEGFA | VTN | WNT11 | WNT4 | WNT5A | WWC1
1
18. Benzo(a)pyrene myotube differentiation fulvestrant fulvestrant inhibits the reaction [Benzo(a)pyrene results in decreased myotube differentiation] 1: Homo sapiens Muscle, Skeletal | Cells, Cultured
16 genes: AVPR1A | CAV3 | GPX1 | GSK3B | HACD1 | INS2 | MEF2C | MET | MYOD1 | MYOG | NFATC3 | SHH | SKI | SORT1 | STIM1 | WNT1
1
19. Benzo(a)pyrene DNA damage response, detection of DNA damage ARNT ARNT protein affects the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Hep G2 Cells
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
20. Benzo(a)pyrene cell proliferation resveratrol resveratrol inhibits the reaction [Benzo(a)pyrene results in increased cell proliferation] 1: Mus musculus Fibroblasts | Cell Line, Transformed
327 genes: ACE | ACHE | ADRA1B | ADRA1D | AKT1 | ALK | ALKBH3 | APPL2 | AR | AREG | ARHGEF1 | ASAH2 | ASCC3 | AURKB | AXIN2 | BAD | BAX | BCAR1 | BCAT1 | BCL2 | BCL2L1 | BIN1 | BMP4 | BOK | BOP1 | BRAT1 | BRCA2 | BST2 | BUB1 | BUB1B | BYSL | CBFA2T3 | CD160 | CD276 | CD34 | CD5 | CD70 | CD74 | CD81 | CDC14A | CDC16 | CDC25A | CDC25C | CDC27 | CDK1 | CDK4 | CDK5R1 | CDK5RAP3 | CDK9 | CDV3 | CENPF | CEP120 | CFB | CITED1 | CITED2 | CKLF | CKS1B | CKS2 | CLK1 | COL4A3BP | CREBBP | CREG1 | CSE1L | CSF1 | CSF1R | CSGALNACT1 | CSPG4 | CTNNB1 | CUL1 | CUL5 | CUZD1 | CXCL1 | CYP1A1 | CYR61 | DAB2 | DACH1 | DAZAP1 | DCTN2 | DDIT4 | DICER1 | DKC1 | DLG1 | DLGAP5 | DLX5 | DNPH1 | DTYMK | DUSP22 | E2F8 | E4F1 | ECD | EDNRA | EGFR | EIF4B | EMP1 | EMP2 | ENPEP | ENTPD5 | EPO | EPS15 | EPS8 | ERBB2 | ERCC1 | ERCC2 | EREG | ERG | ESRRB | EVI5 | FAM83D | FBXL7 | FER | FES | FGF1 | FGF13 | FGF16 | FGF18 | FGF2 | FOXC1 | FOXC2 | FPGS | FSCN1 | FURIN | GAS6 | GBX2 | GCG | GDNF | GFI1B | GH1 | GLUL | GMNC | GNL3 | GPX1 | GRPR | GSK3B | H3F3A | H3F3B | HDGF | HGF | HHEX | HLCS | HMGA2 | HOXB4 | HRAS | HTR1A | ID4 | IFNAR2 | IGF1 | IGFBP4 | IGSF8 | IL12B | IL15RA | IL18 | IL18RAP | IL1A | IL2RA | INSIG1 | INSL4 | IRF2 | IRS2 | ISG20 | ITGA2 | KDM1A | KHDRBS1 | KIF15 | KIF2C | KITLG | KLF10 | KRT16 | LAMA5 | LGI1 | LIG4 | LIPG | LRP1 | LY6E | LY86 | MAP2K1 | MAP3K11 | MAP3K2 | MAP3K20 | MAP4K1 | MAP7 | MAPRE2 | MAS1 | MATK | MCM10 | MCM7 | MDM4 | MELK | MET | MIA | MIF | MKI67 | MNAT1 | MORF4L1 | MOV10L1 | MRE11A | MT3 | MVP | MXD1 | MYB | MYC | MYH10 | NANOG | NASP | NBN | NCF1 | NEDD8 | NKX6-1 | NPY | NUDC | NUMB | NUPR1 | OCA2 | ORC1 | OSM | OTUD6B | PA2G4 | PAK4 | PCNA | PDAP1 | PDK1 | PDPN | PDS5B | PDXK | PDZK1 | PELO | PEMT | PES1 | PICALM | PIM1 | PIM2 | PLCE1 | PLK1 | POLA1 | PPARD | PRDX1 | PRKD1 | PRKDC | PRL | PSPHP1 | PTEN | PTGES3 | PTMA | PTPN6 | PURB | PURBB | RAF1 | RAP1B | RAPGEF3 | RASGRP4 | RBBP7 | RETNLB | RHBDF1 | ROS1 | RPL23A | RPL29 | RPS27 | RRN3 | SBDS | SCRIB | SDCBP2 | SERPINF1 | SHH | SIPA1 | SIX1 | SIX2 | SKI | SKP2 | SORL1 | SOX11 | SOX2 | SPHK2 | SRA1 | SRC | SRGAP2 | STAT3 | STAT4 | STIL | SYK | TACC1 | TACC3 | TBCK | TBX1 | TBX20 | TCF19 | TCF7L2 | TFDP1 | TGFB1 | TGFB2 | THOC6 | THPO | TNF | TNFRSF1B | TNFSF13B | TNFSF9 | TOP2A | TP53 | TP63 | TPT1 | TPX2 | TRAIP | TRP63 | TSPAN5 | TSPO | TXLNA | TXN | TXNRD1 | UBE2V2 | UBR5 | UCHL1 | UHRF1 | UHRF2 | USP13 | USP28 | USP8 | VEGFA | VEGFD | VPS25 | VPS36 | VTI1B | VTN | XRCC5 | YAP1 | YME1L1 | ZEB1 | ZFP36L1 | ZFP36L2 | ZPR1
1
21. Benzo(a)pyrene lipid catabolic process Benzo(a)pyrene results in increased lipid catabolic process 1: Mus musculus Lung
82 genes: ABHD2 | ABHD4 | ADORA1 | AKR1D1 | APOA4 | APOB | APOC2 | APOC3 | BSCL2 | CEL | CES1D | CYP39A1 | DAGLB | DDHD2 | ENPP2 | GALC | HINT2 | HRASLS | INS2 | IRS1 | LIPC | LIPG | LIPH | LPL | MGLL | MITF | NAPEPLD | NCEH1 | NEU2 | NEU3 | NEU4 | PAFAH1B1 | PAFAH1B3 | PAFAH2 | PCK1 | PCK2 | PLA1A | PLA2G10 | PLA2G12A | PLA2G16 | PLA2G1B | PLA2G2A | PLA2G2D | PLA2G3 | PLA2G4A | PLA2G4D | PLA2G4E | PLA2G5 | PLA2G6 | PLA2G7 | PLB1 | PLCB1 | PLCB3 | PLCB4 | PLCD1 | PLCD3 | PLCD4 | PLCE1 | PLCG1 | PLCG2 | PLCL1 | PLCL2 | PLCXD2 | PLD1 | PLD2 | PLD3 | PLD4 | PNLIPRP1 | PNLIPRP2 | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA6 | PNPLA7 | PNPLA8 | PPT1 | PRDX6 | RAB7 | RAB7A | SMPDL3B | SULT2A1 | TBL1XR1
3
22. Benzo(a)pyrene positive regulation of locomotion involved in locomotory behavior Benzo(a)pyrene results in increased positive regulation of locomotion involved in locomotory behavior 1: Danio rerio   1 gene: VPS35 1
23. Benzo(a)pyrene cell proliferation eupatorin-5-methyl ether Benzo(a)pyrene promotes the reaction [eupatorin-5-methyl ether results in decreased cell proliferation] 1: Homo sapiens MCF-7 Cells
327 genes: ACE | ACHE | ADRA1B | ADRA1D | AKT1 | ALK | ALKBH3 | APPL2 | AR | AREG | ARHGEF1 | ASAH2 | ASCC3 | AURKB | AXIN2 | BAD | BAX | BCAR1 | BCAT1 | BCL2 | BCL2L1 | BIN1 | BMP4 | BOK | BOP1 | BRAT1 | BRCA2 | BST2 | BUB1 | BUB1B | BYSL | CBFA2T3 | CD160 | CD276 | CD34 | CD5 | CD70 | CD74 | CD81 | CDC14A | CDC16 | CDC25A | CDC25C | CDC27 | CDK1 | CDK4 | CDK5R1 | CDK5RAP3 | CDK9 | CDV3 | CENPF | CEP120 | CFB | CITED1 | CITED2 | CKLF | CKS1B | CKS2 | CLK1 | COL4A3BP | CREBBP | CREG1 | CSE1L | CSF1 | CSF1R | CSGALNACT1 | CSPG4 | CTNNB1 | CUL1 | CUL5 | CUZD1 | CXCL1 | CYP1A1 | CYR61 | DAB2 | DACH1 | DAZAP1 | DCTN2 | DDIT4 | DICER1 | DKC1 | DLG1 | DLGAP5 | DLX5 | DNPH1 | DTYMK | DUSP22 | E2F8 | E4F1 | ECD | EDNRA | EGFR | EIF4B | EMP1 | EMP2 | ENPEP | ENTPD5 | EPO | EPS15 | EPS8 | ERBB2 | ERCC1 | ERCC2 | EREG | ERG | ESRRB | EVI5 | FAM83D | FBXL7 | FER | FES | FGF1 | FGF13 | FGF16 | FGF18 | FGF2 | FOXC1 | FOXC2 | FPGS | FSCN1 | FURIN | GAS6 | GBX2 | GCG | GDNF | GFI1B | GH1 | GLUL | GMNC | GNL3 | GPX1 | GRPR | GSK3B | H3F3A | H3F3B | HDGF | HGF | HHEX | HLCS | HMGA2 | HOXB4 | HRAS | HTR1A | ID4 | IFNAR2 | IGF1 | IGFBP4 | IGSF8 | IL12B | IL15RA | IL18 | IL18RAP | IL1A | IL2RA | INSIG1 | INSL4 | IRF2 | IRS2 | ISG20 | ITGA2 | KDM1A | KHDRBS1 | KIF15 | KIF2C | KITLG | KLF10 | KRT16 | LAMA5 | LGI1 | LIG4 | LIPG | LRP1 | LY6E | LY86 | MAP2K1 | MAP3K11 | MAP3K2 | MAP3K20 | MAP4K1 | MAP7 | MAPRE2 | MAS1 | MATK | MCM10 | MCM7 | MDM4 | MELK | MET | MIA | MIF | MKI67 | MNAT1 | MORF4L1 | MOV10L1 | MRE11A | MT3 | MVP | MXD1 | MYB | MYC | MYH10 | NANOG | NASP | NBN | NCF1 | NEDD8 | NKX6-1 | NPY | NUDC | NUMB | NUPR1 | OCA2 | ORC1 | OSM | OTUD6B | PA2G4 | PAK4 | PCNA | PDAP1 | PDK1 | PDPN | PDS5B | PDXK | PDZK1 | PELO | PEMT | PES1 | PICALM | PIM1 | PIM2 | PLCE1 | PLK1 | POLA1 | PPARD | PRDX1 | PRKD1 | PRKDC | PRL | PSPHP1 | PTEN | PTGES3 | PTMA | PTPN6 | PURB | PURBB | RAF1 | RAP1B | RAPGEF3 | RASGRP4 | RBBP7 | RETNLB | RHBDF1 | ROS1 | RPL23A | RPL29 | RPS27 | RRN3 | SBDS | SCRIB | SDCBP2 | SERPINF1 | SHH | SIPA1 | SIX1 | SIX2 | SKI | SKP2 | SORL1 | SOX11 | SOX2 | SPHK2 | SRA1 | SRC | SRGAP2 | STAT3 | STAT4 | STIL | SYK | TACC1 | TACC3 | TBCK | TBX1 | TBX20 | TCF19 | TCF7L2 | TFDP1 | TGFB1 | TGFB2 | THOC6 | THPO | TNF | TNFRSF1B | TNFSF13B | TNFSF9 | TOP2A | TP53 | TP63 | TPT1 | TPX2 | TRAIP | TRP63 | TSPAN5 | TSPO | TXLNA | TXN | TXNRD1 | UBE2V2 | UBR5 | UCHL1 | UHRF1 | UHRF2 | USP13 | USP28 | USP8 | VEGFA | VEGFD | VPS25 | VPS36 | VTI1B | VTN | XRCC5 | YAP1 | YME1L1 | ZEB1 | ZFP36L1 | ZFP36L2 | ZPR1
1
24. Benzo(a)pyrene cell death Benzo(a)pyrene results in increased cell death 1: Homo sapiens Trophoblasts | Cell Line
35 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | CACNA1A | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | EMP3 | FAF1 | FOSL2 | GSDME | GZMM | HMOX1 | KLK8 | MAP3K10 | MAP3K11 | MAP3K20 | NDOR1 | NUP62 | OPTN | PARP4 | PMP22 | PNPLA8 | PRKD2 | PTGER3 | SNCAIP | SUSD6 | TGFB2 | TRAF6 | VAPA
1
25. Benzo(a)pyrene positive regulation of superoxide anion generation Calcitriol [Benzo(a)pyrene co-treated with Calcitriol] results in increased positive regulation of superoxide anion generation 1: Homo sapiens U937 Cells
16 genes: AGT | AGTR1A | CRP | CXCL1 | CYBA | EGFR | F2RL1 | FPR2 | GSTP1 | IL18 | ITGAM | ITGB2 | MAPT | PRKCD | SOD1 | TGFB1
1
26. Benzo(a)pyrene negative regulation of chromosome segregation Benzo(a)pyrene results in increased negative regulation of chromosome segregation 1: Homo sapiens Bronchi | Epithelial Cells | Cell Line 1 gene: CHTF18 1
27. Benzo(a)pyrene mitotic cell cycle arrest Benzo(a)pyrene results in increased mitotic cell cycle arrest 1: Homo sapiens MCF-7 Cells
13 genes: CDKN1A | CDKN1B | DDIAS | DUSP1 | E4F1 | FAP | GADD45A | MAGI2 | MCPH1 | PNPT1 | RGCC | TP53 | TRP53
1
28. Benzo(a)pyrene positive regulation of glutathione peroxidase activity Plant Extracts Plant Extracts inhibits the reaction [Benzo(a)pyrene results in decreased positive regulation of glutathione peroxidase activity] 1: Mus musculus Lung 1 gene: SNCA 1
29. Benzo(a)pyrene monooxygenase activity Benzo(a)pyrene results in increased monooxygenase activity 1: Rattus norvegicus Liver
103 genes: BCO1 | CH25H | COQ7 | CYP11A1 | CYP11B2 | CYP17A1 | CYP19A1 | CYP19A1B | CYP19A2 | CYP1A | CYP1A1 | CYP1A2 | CYP1B1 | CYP1C1 | CYP1C2 | CYP1D1 | CYP20A1 | CYP21A1 | CYP21A2 | CYP24A1 | CYP26A1 | CYP26B1 | CYP27A1 | CYP27A7 | CYP2AA1 | CYP2AA12 | CYP2AA7 | CYP2B10 | CYP2B19 | CYP2B6 | CYP2B9 | CYP2C19 | CYP2C29 | CYP2C38 | CYP2C40 | CYP2C55 | CYP2C66 | CYP2D10 | CYP2D22 | CYP2D6 | CYP2D9 | CYP2E1 | CYP2F2 | CYP2G1 | CYP2J2 | CYP2J5 | CYP2N13 | CYP2R1 | CYP2S1 | CYP2U1 | CYP2W1 | CYP2X7 | CYP2Y3 | CYP-35A5 | CYP-35B1 | CYP-35C1 | CYP39A1 | CYP3A11 | CYP3A13 | CYP3A16 | CYP3A25 | CYP3A4 | CYP3A41A | CYP3A5 | CYP3A65 | CYP3A7 | CYP3C1 | CYP46A1 | CYP4A12B | CYP4A14 | CYP4B1 | CYP4F11 | CYP4F12 | CYP4F14 | CYP4F18 | CYP4F2 | CYP4F5 | CYP4X1 | CYP51 | CYP7A1 | CYP7B1 | CYP8B1 | DOHH | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | KMO | MICAL1 | MICAL2 | MICAL3 | MOXD1 | PAH | PAM | PTGIS | RASSF9 | TBXAS1 | TH | TPH1 | TYRP1 | YWHAH | YWHAZ
1
30. Benzo(a)pyrene wound healing, spreading of cells TGIF1 TGIF1 protein affects the reaction [Benzo(a)pyrene results in increased wound healing, spreading of cells] 1: Homo sapiens Lung | Cell Line, Tumor
17 genes: ARHGAP35 | CARMIL2 | CD151 | CD44 | CEACAM1 | CYR61 | DDR1 | FLNA | LCP1 | PARD3 | PDCD10 | PDPN | PTK2 | RHOC | SNAI2 | TMEFF2 | TOR1A
1
31. Benzo(a)pyrene optic vesicle morphogenesis Estradiol Estradiol inhibits the reaction [Benzo(a)pyrene results in decreased optic vesicle morphogenesis] 1: Danio rerio Embryo, Nonmammalian
2 genes: EFNB1 | TFAP2A
1
32. Benzo(a)pyrene lipid catabolic process Benzo(a)pyrene results in increased lipid catabolic process 1: Mus musculus Serum
82 genes: ABHD2 | ABHD4 | ADORA1 | AKR1D1 | APOA4 | APOB | APOC2 | APOC3 | BSCL2 | CEL | CES1D | CYP39A1 | DAGLB | DDHD2 | ENPP2 | GALC | HINT2 | HRASLS | INS2 | IRS1 | LIPC | LIPG | LIPH | LPL | MGLL | MITF | NAPEPLD | NCEH1 | NEU2 | NEU3 | NEU4 | PAFAH1B1 | PAFAH1B3 | PAFAH2 | PCK1 | PCK2 | PLA1A | PLA2G10 | PLA2G12A | PLA2G16 | PLA2G1B | PLA2G2A | PLA2G2D | PLA2G3 | PLA2G4A | PLA2G4D | PLA2G4E | PLA2G5 | PLA2G6 | PLA2G7 | PLB1 | PLCB1 | PLCB3 | PLCB4 | PLCD1 | PLCD3 | PLCD4 | PLCE1 | PLCG1 | PLCG2 | PLCL1 | PLCL2 | PLCXD2 | PLD1 | PLD2 | PLD3 | PLD4 | PNLIPRP1 | PNLIPRP2 | PNPLA1 | PNPLA2 | PNPLA3 | PNPLA6 | PNPLA7 | PNPLA8 | PPT1 | PRDX6 | RAB7 | RAB7A | SMPDL3B | SULT2A1 | TBL1XR1
1
33. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 2: Mus musculus | Rattus norvegicus Lung
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
2
34. Benzo(a)pyrene glutathione peroxidase activity Benzo(a)pyrene results in decreased glutathione peroxidase activity 1: Homo sapiens Erythrocytes
24 genes: GPX1 | GPX1B | GPX2 | GPX3 | GPX4 | GPX4A | GPX4B | GPX5 | GPX7 | GPX8 | GSTA1 | GSTK1 | GSTM2 | GSTM7 | GSTP1 | GSTP2 | GSTS1 | GSTT1 | GSTT2 | GSTZ1 | MGST1 | MGST2 | MGST3 | PRDX6
1
35. Benzo(a)pyrene cellular pigment accumulation Benzo(a)pyrene results in increased cellular pigment accumulation 1: Mytilus galloprovincialis Digestive System | Exocrine Glands 1 gene: SHROOM3 1
36. Benzo(a)pyrene DNA metabolic process Benzo(a)pyrene results in increased DNA metabolic process 1: Homo sapiens Breast | Epithelial Cells | Cells, Cultured
25 genes: ADRA1D | DMC1 | DNASE1L1 | DNASE2 | DNASE2A | DNASE2B | HELQ | IGFBP4 | KPNA2 | MKI67 | MYO18A | NME1 | NT5E | PARP1 | POLG | PTBP1 | RAD51 | RAN | SMARCAL1 | SPO11 | TOP2A | TOPBP1 | TREX1 | TREX2 | WRN
1
37. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Liver | Cells
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
38. Benzo(a)pyrene glutathione derivative biosynthetic process Benzo(a)pyrene results in decreased glutathione derivative biosynthetic process 1: Mus musculus Lung
21 genes: AKR1A1 | ESD | GSTA1 | GSTA2 | GSTA3 | GSTA4 | GSTK1 | GSTM1 | GSTM2 | GSTM3 | GSTM4 | GSTM5 | GSTO1 | GSTO2 | GSTP1 | GSTT1 | GSTZ1 | HPGDS | MGST1 | MGST2 | MGST3
1
39. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 1: Mus musculus Liver
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
2
40. Benzo(a)pyrene glutathione biosynthetic process Benzo(a)pyrene results in decreased glutathione biosynthetic process 1: Homo sapiens Erythrocytes
12 genes: CHAC1 | CHAC2 | GCLC | GCLM | GGCT | GGT1 | GGT5 | GGT6 | GSS | HAGH | MGST2 | OPLAH
1
41. Benzo(a)pyrene cellular lipid catabolic process Benzo(a)pyrene results in increased cellular lipid catabolic process 1: Mus musculus Liver
4 genes: ACADL | MT3 | PNPLA2 | SIRT2
1
42. Benzo(a)pyrene cell migration Benzo(a)pyrene results in increased cell migration 1: Homo sapiens Lung | Cell Line, Tumor
159 genes: ABI2 | ABP1 | ACVR1 | ADAM9 | ADAMTS12 | ADGRE2 | ADGRG1 | ANG | ARC | ARHGAP35 | ARPC5 | ATN1 | BAMBI | BCAR1 | BRAT1 | BTG1 | CARMIL1 | CARMIL2 | CCDC88A | CD151 | CD248 | CD24A | CD2AP | CD44 | CD47 | CD63 | CDC42BPB | CDH2 | CDH7 | CDK1 | CEACAM1 | CELF1 | CLASP2 | CLN3 | COL5A1 | CORO1A | CORO1B | CORO7 | CSK | CTGF | CTHRC1 | CUL3 | CXCL12 | CXCR4 | DCHS1 | DGKZ | DOCK1 | EFNA1 | ELMO1 | ELMO2 | ELMO3 | EMP2 | ENG | ENPEP | EPHA2 | EPHA3 | EPHB3 | ERG | FAM83D | FAT1 | FERMT2 | FGFR1 | FGFR4 | FLT1 | FMNL3 | FN1 | FNDC3B | FOXC1 | FSCN1 | FUT8 | FZD2 | GAB2 | GAS6 | GFRA1 | GPC6 | GSK3A | GSK3B | HBEGF | HES1 | HOXA5 | IL12B | ITGA4 | ITGA7 | ITGAV | ITGB1 | ITGB1B | JAM3 | KDR | LAMA5 | LAMB1 | LAMC1 | LCP1 | MDK | MET | MMP14 | MMP2 | MYO18A | NANOS1 | NFATC2 | NODAL | NOX1 | NRP1 | NUP62 | PAFAH1B1 | PAK4 | PALLD | PARP9 | PDGFRA | PDGFRB | PDPK1 | PIK3CB | PIP5K1A | PLCG1 | PODXL | PPP1R9B | PRAG1 | PRPF40A | PSTPIP2 | PTEN | PTPRF | PTPRK | PVR | RAB1A | RELN | RHBDF1 | S1PR1 | SCRIB | SCYL3 | SEMA3AA | SH3BP1 | SH3KBP1 | SIRPA | SIX2 | SLC9A1 | SNAI1 | SNAI2 | SORL1 | SRC | SRGAP1 | SSTR4 | ST14 | STRIP2 | TGFB1 | TGFB2 | TGFBR2 | TGFBR3 | THBS1 | TIAM1 | TNFAIP1 | TNS3 | TREM1 | VAV2 | VAV3 | VEGFA | VTN | WNT11 | WNT4 | WNT5A | WWC1
1
43. Benzo(a)pyrene monooxygenase activity Sulpiride Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased monooxygenase activity] 1: Rattus norvegicus Liver
103 genes: BCO1 | CH25H | COQ7 | CYP11A1 | CYP11B2 | CYP17A1 | CYP19A1 | CYP19A1B | CYP19A2 | CYP1A | CYP1A1 | CYP1A2 | CYP1B1 | CYP1C1 | CYP1C2 | CYP1D1 | CYP20A1 | CYP21A1 | CYP21A2 | CYP24A1 | CYP26A1 | CYP26B1 | CYP27A1 | CYP27A7 | CYP2AA1 | CYP2AA12 | CYP2AA7 | CYP2B10 | CYP2B19 | CYP2B6 | CYP2B9 | CYP2C19 | CYP2C29 | CYP2C38 | CYP2C40 | CYP2C55 | CYP2C66 | CYP2D10 | CYP2D22 | CYP2D6 | CYP2D9 | CYP2E1 | CYP2F2 | CYP2G1 | CYP2J2 | CYP2J5 | CYP2N13 | CYP2R1 | CYP2S1 | CYP2U1 | CYP2W1 | CYP2X7 | CYP2Y3 | CYP-35A5 | CYP-35B1 | CYP-35C1 | CYP39A1 | CYP3A11 | CYP3A13 | CYP3A16 | CYP3A25 | CYP3A4 | CYP3A41A | CYP3A5 | CYP3A65 | CYP3A7 | CYP3C1 | CYP46A1 | CYP4A12B | CYP4A14 | CYP4B1 | CYP4F11 | CYP4F12 | CYP4F14 | CYP4F18 | CYP4F2 | CYP4F5 | CYP4X1 | CYP51 | CYP7A1 | CYP7B1 | CYP8B1 | DOHH | FMO1 | FMO2 | FMO3 | FMO4 | FMO5 | KMO | MICAL1 | MICAL2 | MICAL3 | MOXD1 | PAH | PAM | PTGIS | RASSF9 | TBXAS1 | TH | TPH1 | TYRP1 | YWHAH | YWHAZ
1
44. Benzo(a)pyrene positive regulation of apoptotic process Calcitriol | SERPINE1 SERPINE1 protein promotes the reaction [[Benzo(a)pyrene co-treated with Calcitriol] results in increased positive regulation of apoptotic process] 1: Homo sapiens THP-1 Cells
331 genes: ABR | ACE | ACIN1 | ACVR1C | ADAMTSL4 | ADCY10 | ADM | ADRB1 | ADRB2 | AIFM1 | AIFM2 | AKT1 | ALDH1A1 | ALDH1A3 | ANKRD1 | ANO6 | ANXA1 | ANXA5 | APAF1 | APBB2 | ARHGEF1 | ARHGEF16 | ARHGEF17 | ARHGEF18 | ARHGEF2 | ARHGEF3 | ARHGEF5 | ARHGEF6 | ARHGEF7 | ARHGEF9 | ARL6IP5 | ATF4 | ATF6 | ATG7 | ATM | B4GALT1 | BAD | BARD1 | BAX | BBC3 | BCL10 | BCL2L1 | BCL2L11 | BCL6 | BCLAF1 | BID | BIK | BIN1 | BMF | BMP2 | BMP4 | BMP7 | BNIP3 | BNIP3L | BOK | C6 | CAMK1D | CASP2 | CASP3 | CASP6 | CASP8 | CASP9 | CASPB | CCAR1 | CCK | CDK19 | CDK4 | CDKN2A | CLU | CRADD | CREB1 | CTLA4 | CTNNB1 | CTNNBL1 | CTRB1 | CYP1B1 | CYR61 | DAB2IP | DAPK3 | DCUN1D3 | DDIT3 | DDX19A | DDX20 | DDX3X | DEGS1 | DFFA | DHODH | DIABLO | DKKL1 | DNAJA1 | DNAJA3 | DNM1L | DUSP1 | DUSP6 | E2F1 | ECR | ECT2 | EEF1A2 | EEF1E1 | EFHC1 | EGLN1 | EIF2AK2 | EIF5A | EPHA7 | ERCC3 | ESR2 | FADD | FAF1 | FAM162A | FAS | FASLG | FGD4 | FOSL1 | FOXA1 | FOXO1 | FOXO3 | FRZB | FZD9 | GADD45A | GADD45B | GADD45G | GAL | GATA6 | GNA13 | GNAQ | GPER1 | GRIN1 | GRIN2A | GSK3B | GZMA | HIF1A | HMGA2 | HMGB1 | HMOX1 | HOXA5 | HPGD | HRG | HSPD1 | HTT | ID3 | IDO1 | IFIT2 | IFNG | IGF2R | IGFBP3 | IL18 | IL1B | IL24 | IL6 | ING3 | ING4 | ING5 | INPP5D | IP6K2 | IRF5 | ITGA6 | ITGB1 | ITSN1 | JAK2 | JUN | KALRN | KCNMA1 | KLF11 | KNG1 | LDHA | LILRB1 | LPAR1 | LRP6 | MAP2K4 | MAP2K6 | MAP3K1 | MAP3K10 | MAP3K11 | MAP3K20 | MAP3K5 | MAPK8 | MAPK9 | MCF2L | MELK | MIR29A | MLLT11 | MMP2 | MMP9 | MNDA | MOAP1 | MSX2 | MTCH1 | NCOA1 | NELL1 | NET1 | NEURL1A | NEUROD1 | NF1 | NGEF | NGF | NGFR | NOS2 | NOS3 | NOTCH1 | NOTCH2 | NOX4 | NR4A1 | NSMAF | NTRK3 | NUPR1 | OBSCN | OSGIN1 | P2RX7 | PAWR | PDCD1 | PDCD2 | PDCD5 | PDE5A | PDGFRB | PDIA3 | PHLDA1 | PHLDA3 | PIDD1 | PLA2G4A | PLEKHG2 | PLSCR1 | PMAIP1 | PNMA2 | PNMA3 | POU4F1 | PPARG | PPID | PPP1R15A | PPP2CA | PREX1 | PRKCD | PRKDC | PRKN | PSEN2 | PTEN | PTGS2 | PTN | PTPRF | PXT1 | PYCARD | RACK1 | RARB | RARG | RASGRF2 | RASSF2 | RASSF6 | RBCK1 | RBM5 | RDX | RELA | REST | RHOB | RIPK1 | RIPK2 | RPS27A | RPS6 | RPS6KA2 | RRP1B | RXRA | RYBP | SCIN | SCRIB | SEPT4 | SERPINA3C | SFRP1 | SFRP2 | SFRP4 | SIAH1A | SLC9A1 | SLIT2 | SLK | SMPD2 | SNCA | SOD1 | SOS1 | SOX4 | SP110 | SQSTM1 | SRC | STEAP3 | STK17A | STK3 | STK4 | TCF7L2 | TEX261 | TFAP4 | TFPT | TGFB1 | TGFB2 | TGFB3 | TGFBR1 | TGM2 | TIAM1 | TIAM2 | TLR3 | TLR4 | TNF | TNFAIP8 | TNFRSF12A | TNFRSF8 | TNFSF10 | TOMM22 | TOP2A | TP53 | TP53INP1 | TP73 | TRAF4 | TRAF6 | TRIM35 | TRIO | TRP53 | TRP53INP1 | TRP73 | TRPV1 | TSC22D1 | TSPO | TXNIP | UACA | UBA52 | UBC | UBD | UNC13B | UNC5C | USP27X | VAV1 | VAV2 | VAV3 | WNT11 | WT1 | ZFP346 | ZMAT3
1
45. Benzo(a)pyrene vitamin E biosynthetic process Quercetin Quercetin inhibits the reaction [Benzo(a)pyrene results in decreased vitamin E biosynthetic process] 1: Mus musculus Lung 1 gene: PLTP 1
46. Benzo(a)pyrene reactive oxygen species metabolic process Benzo(a)pyrene results in increased reactive oxygen species metabolic process 1: Homo sapiens Keratinocytes | Cells, Cultured
34 genes: ATPIF1 | BCL2 | BNIP3 | CAT | CTGF | CYBA | CYR61 | DDIT4 | DUOX1 | EPHX2 | GLS2 | LRRK2 | MET | MPV17 | MPV17L | ND2 | NDUFA13 | NDUFS4 | NOX4 | P2RX7 | PAX2 | PDGFB | PDK4 | PMAIP1 | PRDX4 | PREX1 | SESN1 | SESN2 | SFTPD | SH3PXD2A | SOD1 | SOD2 | SPAST | VAV1
1
47. Benzo(a)pyrene cell death Vitamin E Vitamin E inhibits the reaction [Benzo(a)pyrene results in increased cell death] 1: Homo sapiens Lung | Epithelial Cells | Cell Line
35 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | CACNA1A | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | EMP3 | FAF1 | FOSL2 | GSDME | GZMM | HMOX1 | KLK8 | MAP3K10 | MAP3K11 | MAP3K20 | NDOR1 | NUP62 | OPTN | PARP4 | PMP22 | PNPLA8 | PRKD2 | PTGER3 | SNCAIP | SUSD6 | TGFB2 | TRAF6 | VAPA
1
48. Benzo(a)pyrene reactive oxygen species biosynthetic process resveratrol resveratrol inhibits the reaction [Benzo(a)pyrene results in increased reactive oxygen species biosynthetic process] 1: Mus musculus Fibroblasts | Cell Line, Transformed
2 genes: GBF1 | NOX4
1
49. Benzo(a)pyrene lipid biosynthetic process Benzo(a)pyrene results in increased lipid biosynthetic process 1: Rattus norvegicus Hepatocytes | Cells, Cultured
22 genes: ACLY | ACSL1 | ACSL4 | ACSS2 | AGMO | AGPS | CH25H | CLN8 | DCTN6 | FA2H | FASN | FDFT1 | GCG | GPAT4 | MSMO1 | PRKAA2 | PRPF19 | SC5D | SCD | SCD1 | SREBF1 | SREBF2
1
50. Benzo(a)pyrene glutathione peroxidase activity Silymarin Silymarin inhibits the reaction [Benzo(a)pyrene results in decreased glutathione peroxidase activity] 1: Homo sapiens Erythrocytes
24 genes: GPX1 | GPX1B | GPX2 | GPX3 | GPX4 | GPX4A | GPX4B | GPX5 | GPX7 | GPX8 | GSTA1 | GSTK1 | GSTM2 | GSTM7 | GSTP1 | GSTP2 | GSTS1 | GSTT1 | GSTT2 | GSTZ1 | MGST1 | MGST2 | MGST3 | PRDX6
1
1–50 of 379 results.