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Chemical Benzo(a)pyrene

1–50 of 340 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. benzo(a)pyrene-DNA adduct DNA damage response, detection of DNA damage Benzo(a)pyrene [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] which results in increased abundance of benzo(a)pyrene-DNA adduct 1: Mus musculus Pulmonary Alveoli | Cell Line   1
2. benzo(a)pyrene-DNA adduct DNA damage response, detection of DNA damage 1-methylanthracene | Benzo(a)pyrene | fluoranthene [1-methylanthracene co-treated with fluoranthene] promotes the reaction [[Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] which results in increased abundance of benzo(a)pyrene-DNA adduct] 1: Mus musculus Pulmonary Alveoli | Cell Line   1
3. Benzo(a)pyrene learning Benzo(a)pyrene results in decreased learning 1: Rattus norvegicus  
56 genes: AAAS | AMN | APP | ARC | ATAD1 | ATP8A1 | ATXN1 | BCHE | BDNF | CIC | CLDN5 | CNTN2 | COMT | CTNND2 | DRD1 | EIF2AK4 | EPHB2 | FGF13 | FOSL1 | FYN | GMFB | GRIN1 | GRIN2A | GRIN2B | GRM4 | HRH3 | HTT | INSR | JPH3 | JUN | MECP2 | NLGN3 | NPAS4 | NRXN1 | NRXN3 | NTRK2 | PAK6 | PARK2 | PLCB1 | PPP1R9B | PRKAR2B | PRKN | PTGS1 | PTGS2 | PTN | RELN | SHANK2 | SHANK3 | SLC12A5 | SLC24A2 | SORCS3 | STRA6 | SYNJ1 | TH | TLR2 | UBA6
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4. Benzo(a)pyrene apoptotic process Eicosapentaenoic Acid Eicosapentaenoic Acid inhibits the reaction [Benzo(a)pyrene results in increased apoptotic process] 1: Rattus norvegicus Liver | Epithelial Cells | Cell Line
521 genes: AATF | AATK | ACIN1 | ACVR1C | ADAMTSL4 | ADORA2A | ADRB1 | AEN | AHR | AIFM1 | AIMP1 | AIMP2 | AKT1 | AKTIP | ALDOC | ALOX15B | APAF1 | APIP | APLP1 | APP | ARG2 | ARHGEF6 | ARRB1 | ASAH2 | ATG4D | ATM | AVEN | AVP | BABAM2 | BAD | BAG1 | BAG3 | BAG4 | BAG6 | BAX | BBC3 | BCAP31 | BCL10 | BCL2 | BCL2A1 | BCL2L1 | BCL2L11 | BCL2L12 | BCL2L15 | BCL2L2 | BCL7B | BCL7C | BCLAF1 | BECN1 | BEX2 | BFAR | BID | BIK | BIRC2 | BIRC3 | BIRC5 | BIRC6 | BLCAP | BMF | BMX | BNIP2 | BNIP3 | BNIP3L | BOK | BRAT1 | BRCA1 | BRMS1 | BTK | BUB1 | BUB1B | C1D | C5AR1 | CADM1 | CAPN3 | CARD6 | CASP2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP9 | CASR | CCAR1 | CCK | CCL6 | CD14 | CD2 | CD27 | CD5L | CDCA7 | CDIP1 | CDK1 | CDKN2A | CFLAR | CGB3 | CHAC1 | CHEK1 | CHEK2 | CHI3L1 | CHIA | CHMP3 | CIAPIN1 | CIB1 | CIDEA | CIDEC | CITED1 | CKAP2 | COMP | CRADD | CSE1L | CSNK2A2 | CSRNP1 | CSRNP2 | CST3 | CTNNBL1 | CTSC | CTSH | CUL1 | CUL7 | CXCR3 | CXCR4 | CYCS | CYFIP2 | DAB2 | DAB2IP | DAP | DAP3 | DAPK1 | DAPK2 | DAPK3 | DCC | DDIAS | DDIT3 | DDIT4 | DDX3X | DDX47 | DEDD | DEDD2 | DFFA | DFFB | DHCR24 | DIABLO | DIABLOA | DIAP1 | DIDO1 | DIO3 | DLC1 | DNAJA3 | DNASE2A | DOCK1 | DPEP1 | DPF1 | DPF2 | DRAM1 | DRAM2 | DUSP22 | DYRK2 | E2F1 | EAF2 | ECE1 | EGLN3 | EI24 | EIF5A | ELMO1 | ELMO2 | ELMO3 | EMC4 | EPB41L3 | EPHA2 | EPHA7 | EPO | ERCC2 | ERCC3 | ERN2 | ESPL1 | EVA1A | FADD | FAF1 | FAIM | FAIM2 | FAM162A | FAM3B | FAP | FAS | FASLG | FASTK | FATE1 | FGF13 | FGFR3 | FHIT | FOXO1 | FOXO3 | FXR1 | G0S2 | G2E3 | GADD45A | GADD45B | GADD45G | GAPDH | GAS6 | GH | GHITM | GJA1 | GJB6 | GLRX2 | GPER1 | GPR65 | GPX1 | GRAMD4 | GREM1 | GRK5 | GSN | GULP1 | GZMA | GZMM | HCAR2 | HIF3A | HINT1 | HINT2 | HIP1 | HIPK2 | HIPK3 | HMOX1 | HRAS | HTATIP2 | HTT | IER3 | IFIT2 | IFNG | IGFBP3 | IKBKG | IL1A | IL1B | IL24 | IL2RA | ING4 | INPP5D | IRAK3 | IRF1 | IRF3 | ITCH | ITGB2 | ITPR1 | JADE1 | JAK2 | KANK2 | KIF1B | KLF11 | KMT2A | KRT20 | LCK | LCN2 | LGALS1 | LGALS7 | LMNB1 | LSP1 | LY86 | MADD | MAGEH1 | MAGI3 | MAL | MALT1 | MAP1S | MAP2K4 | MAP2K6 | MAP3K10 | MAP3K5 | MAP3K7 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | MCM2 | MECOM | MEF2C | MELK | MFSD10 | MKNK2 | MOAP1 | MRPL41 | MRPS30 | MT3 | MTCH1 | MX1 | NAE1 | NAIF1 | NAIP | NAIP5 | NCF1 | NCKAP1 | NEK6 | NFKB1 | NFKBIA | NGFR | NME3 | NOD1 | NOTCH2 | NR3C1 | NR4A1 | NSG1 | NTN1 | OGT | OPA1 | P2RX1 | PACS2 | PAK1 | PAK4 | PAK6 | PARM1 | PARP1 | PAWR | PCSK9 | PDCD1 | PDCD10 | PDCD2 | PDCD4 | PDCD5 | PDCD6IP | PDCL3 | PEA15 | PEG10 | PEG3 | PERP | PGLYRP1 | PHLDA1 | PHLDA2 | PHLDA3 | PHLPP1 | PIDD1 | PIM1 | PIM2 | PIM3 | PKN2 | PLEKHF1 | PLK3 | PLSCR1 | PMAIP1 | PML | POLB | POLR2G | POU4F2 | PPARD | PPID | PPIF | PPM1F | PPP1R15A | PPP2CA | PRDX5 | PRF1 | PRKCA | PRKCB | PRKCD | PRKCE | PRKD1 | PRUNE2 | PSMD10 | PSME3 | PTEN | PTK2B | PTPN6 | PTRH2 | PURB | PYCARD | RABEP1 | RACK1 | RAF1 | RALB | RASSF5 | RASSF6 | RB1 | RBM25 | RBM5 | RFFL | RHBDD1 | RHOB | RIPK1 | RIPK2 | RMDN3 | RNF130 | RNF144B | RNF152 | RNF216 | RNF34 | ROCK1 | RPS3 | RPS6KA1 | RPS6KA3 | RRAGC | RRP1B | RTKN | RTN3 | RTN4 | RYBP | S100A14 | S100A8 | S100A9 | SEMA3A | SEMA6A | SEPT4 | SERPINA3G | SERPINB9 | SFRP2 | SFRP5 | SGK1 | SGMS1 | SGPL1 | SH3GLB1 | SH3KBP1 | SH3RF1 | SHB | SHC4 | SHISA5 | SIAH1A | SIAH2 | SIVA1 | SIX1 | SLC5A11 | SLC5A8 | SLK | SLTM | SMNDC1 | SNCA | SP110 | SQSTM1 | SRA1 | SRGN | STEAP3 | STK17A | STK17B | STK24 | STK3 | STK4 | SULF1 | TAF10 | TAX1BP1 | TCHP | TCIM | TESK2 | TF | TFAP2B | TFPT | TGFBR1 | TGFBR2 | THEM4 | THOC1 | THOC6 | TIA1 | TIAL1 | TIAM1 | TIGAR | TIMM50 | TLR2 | TMBIM4 | TMEM14A | TMEM173 | TMEM214 | TNF | TNFAIP1 | TNFAIP3 | TNFAIP8 | TNFRSF10A | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF18 | TNFRSF19 | TNFRSF1A | TNFRSF1B | TNFRSF21 | TNFRSF9 | TNFSF10 | TNFSF12 | TNFSF9 | TNS4 | TOX3 | TP53 | TP53INP1 | TP63 | TP73 | TPX2 | TRAF1 | TRAF3 | TRAF4 | TRAF5 | TRAF7 | TRAIP | TRIAP1 | TRIB3 | TRIM35 | TRIM39 | TRP53 | TRP53INP1 | TRP63 | TRP73 | TRPV2 | TSPO | UBE2D3 | UNC5A | UNC5B | UNC5C | VIL1 | WNT1 | WT1 | WWOX | XAF1 | XBP1 | XIAP | XKR8 | YARS | YPEL3 | ZC3H12A | ZC3H8 | ZDHHC16 | ZFAND6 | ZFP36L1 | ZFP385A | ZFP385B | ZMAT3 | ZNF385B
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5. Benzo(a)pyrene regulation of mitochondrial membrane potential alpha-naphthoflavone alpha-naphthoflavone inhibits the reaction [Benzo(a)pyrene affects regulation of mitochondrial membrane potential] 1: Rattus norvegicus Liver | Epithelial Cells | Cell Line
20 genes: ADORA2A | BAX | BCL2 | BCL2L1 | CLIC1 | HTT | OPRD1 | PARK2 | PID1 | PINK1 | PPA2 | PPID | PRKN | PYCR1 | SLC25A33 | SLC25A36 | SOD1 | SOD2 | STOX1 | UCP2
1
6. Benzo(a)pyrene C-5 methylation of cytosine Benzo(a)pyrene results in decreased C-5 methylation of cytosine 1: Danio rerio Tissues
3 genes: DNMT1 | DNMT3A | DNMT3B
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7. Benzo(a)pyrene negative regulation of cell proliferation Benzo(a)pyrene results in decreased negative regulation of cell proliferation 1: Rattus norvegicus PC12 Cells
377 genes: ABI1 | ACVRL1 | ADAMTS1 | ADARB1 | ADGRG1 | ADM | ADORA1 | ADORA2A | ADORA2B | ADORA3 | AGT | AIMP2 | ALOX15B | AMBRA1 | APP | AR | ARID2 | ASPH | ATF5 | AXIN2 | AZGP1 | B4GALT1 | BAX | BCHE | BCL11B | BCL2 | BCL6 | BDKRB2 | BECN1 | BMP2 | BMP4 | BMP7 | BRIP1 | BTG1 | BTG2 | BTG3 | BTG4 | CACNB4 | CAV1 | CBFA2T3 | CD37 | CD9 | CDC6 | CDC73 | CDH13 | CDK10 | CDK6 | CDKN1A | CDKN1B | CDKN2A | CDKN2B | CDKN2C | CDKN2D | CDKN3 | CEBPA | CGREF1 | CHD5 | CIB1 | CLMN | COL18A1 | COPS8 | CPEB1 | CSF1R | CSK | CTBP2 | CTCF | CTH | CTNNB1 | CUL1 | CUL2 | CUL4A | CUL5 | CXCL1 | CXCL8 | CYP1B1 | DAB2IP | DDAH1 | DDR1 | DDX20 | DHCR24 | DHRS2 | DIS3L2 | DLC1 | DLG1 | DLG3 | DLG5 | DLL1 | DLL4 | DNAJA3 | DNAJB2 | DPT | DRD2 | E2F7 | EEF1E1 | EIF2AK2 | EMP3 | EREG | ESR2 | ETS1 | ETV3 | F2R | FABP6 | FABP7 | FAM129B | FBXO2 | FEZF1 | FGF2 | FGFBP1 | FGFR3 | FKTN | FLT3 | FNTB | FOSL1 | FOXO4 | FOXP3 | FRZB | FTH1 | FUZ | FZD5 | GABBR1 | GAL | GATA3 | GGNBP2 | GJA1 | GJB6 | GLI3 | GNRH1 | GNRHR | GPER1 | GPNMB | GRM4 | GSDME | H19 | HDAC1 | HDAC4 | HGS | HIST1H2AB | HIST1H2AC | HIST1H2AE | HIST1H2AF | HIST1H2AG | HIST1H2AI | HIST1H2AO | HMGA1 | HMOX1 | HNF4A | HRAS | HRG | HSF1 | HSPA1A | HSPA1B | HSPG2 | IFIT3 | IFITM1 | IFITM3 | IFNG | IFNLR1 | IGF1 | IGFBP3 | IGFBP6 | IGFBP7 | IL10 | IL1A | IL1B | IL1RL1 | IL24 | IL6 | ING2 | ING4 | ING5 | INHBA | INPP5D | INPPL1 | INSM1 | IRF1 | ITGA1 | ITGB1 | JAK2 | JARID2 | JUN | KANK2 | KAT2B | KIFAP3 | KLF10 | KLF11 | KLF13 | KLF4 | KMT2A | LEFTY1 | LIF | LMNA | LYN | LZTS2 | MAGI2 | MAP2K1 | MDM4 | MIR29A | MSX2 | MTBP | MXD4 | MXI1 | MYO16 | MYOCD | MYOG | NACC2 | NDN | NDRG1 | NEURL1A | NF1 | NFE2 | NFIB | NGF | NME1 | NOS1 | NOS3 | NOTCH1 | NOX4 | NPM1 | NR2E3 | NRK | NUP62 | OPRM1 | OPTN | OSM | OVOL2 | P3H1 | P3H2 | PAX6 | PBRM1 | PDCD5 | PDPN | PDS5B | PDX1 | PEMT | PHF14 | PHOX2B | PIM2 | PINX1 | PKD2 | PKP2 | PLG | PLK5 | PLPP1 | PML | PMP22 | PODN | PPARG | PPM1D | PPP1R15A | PPP2R5C | PRKCA | PROX1 | PTEN | PTGES | PTGS2 | PTH1R | PTHLH | PTK2B | PTPN14 | PTPN2 | PTPN6 | PTPRF | PTPRJ | PTPRK | PTTG1 | RAF1 | RARA | RARB | RARG | RARRES1 | RASSF5 | RB1 | RBM10 | RBM38 | RBM5 | REG1 | RERG | REST | RGCC | RIPPLY3 | RNF139 | ROBO1 | RPS6KA2 | RUNX1 | RXRA | S100A11 | SCIN | SCRIB | SERPINE2 | SFRP1 | SFRP2 | SFRP4 | SFRP5 | SH3BP4 | SIRT2 | SIRT6 | SIX5 | SKAP2 | SKI | SLC9A3R1 | SLFN1 | SLFN2 | SLIT2 | SLIT3 | SLURP1 | SMAD1 | SMAD3 | SMARCA2 | SMARCB1 | SMYD2 | SOD2 | SOX4 | SOX7 | SOX9 | SPEG | SPRY1 | SRF | SST | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | STAT3 | STK3 | STK4 | SULT2B1 | TAF6 | TAX1BP3 | TBRG1 | TBX5 | TES | TESC | TFAP2A | TFAP2B | TFAP4 | TFF1 | TGFB1 | TGFB1I1 | TGFB2 | TGFB3 | TGFBR2 | TGIF1 | TIMP2 | TLR2 | TNF | TNFRSF8 | TNFRSF9 | TNS2 | TOB1 | TOB2 | TP53 | TP53INP1 | TP73 | TRIM24 | TRIM35 | TRP53 | TRP53INP1 | TRP73 | TRPV2 | TSPAN32 | UMOD | UTP20 | UVRAG | VDR | VEGFC | VHL | WDR6 | WDR77 | WISP2 | WNT11 | WNT9A | WT1 | XIRP1 | ZBTB17 | ZEB1 | ZNF503
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8. Benzo(a)pyrene fatty acid beta-oxidation Benzo(a)pyrene affects fatty acid beta-oxidation 1: Mus musculus Liver
31 genes: ABCD2 | ABCD3 | ACAA1A | ACAA2 | ACAD11 | ACADL | ACADM | ACADSB | ACADVL | ACOX1 | ACOX2 | ACOXL | ADIPOQ | CPT1A | CPT1B | CPT1C | CRAT | DECR1 | ECH1 | ECI1 | EHHADH | HADH | HADHB | MCAT | NDUFAB1 | PEX5 | PEX7 | PPARD | SESN2 | SLC25A17 | SLC27A2
1
9. Benzo(a)pyrene positive regulation of cell size Benzo(a)pyrene results in decreased positive regulation of cell size 1: Rattus norvegicus PC12 Cells
22 genes: AHR | AKT1 | AKT3 | ATP7A | CDK4 | EDN1 | HIF1A | HSP90AA1 | HSP90AB1 | KDM1A | LTV1 | MYC | MYT1 | OGT | PDK1 | RAPGEF3 | RB1CC1 | RET | RICTOR | TCTP | TP73 | TRP73
1
10. Benzo(a)pyrene myotube differentiation fulvestrant fulvestrant inhibits the reaction [Benzo(a)pyrene results in decreased myotube differentiation] 1: Homo sapiens Muscle, Skeletal | Cells, Cultured
16 genes: AVPR1A | CAV3 | GPX1 | GSK3B | HACD1 | INS2 | MEF2C | MET | MYOD1 | MYOG | NFATC3 | SHH | SKI | SORT1 | STIM1 | WNT1
1
11. Benzo(a)pyrene L-ascorbic acid biosynthetic process hesperetin hesperetin inhibits the reaction [Benzo(a)pyrene results in decreased L-ascorbic acid biosynthetic process] 1: Mus musculus Lung
5 genes: AKR1A1 | GSTO1 | GULO | HAGH | RGN
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12. Benzo(a)pyrene cell migration Benzo(a)pyrene results in increased cell migration 1: Mus musculus Mammary Glands, Animal | Cell Line, Tumor
158 genes: ABI2 | ABP1 | ACVR1 | ADAM9 | ADAMTS12 | ADGRE2 | ADGRG1 | ANG | ARC | ARHGAP35 | ARPC5 | ATN1 | BAMBI | BCAR1 | BRAT1 | BTG1 | CARMIL1 | CARMIL2 | CCDC88A | CD151 | CD248 | CD24A | CD2AP | CD44 | CD47 | CD63 | CDC42BPB | CDH2 | CDH7 | CDK1 | CEACAM1 | CELF1 | CLASP2 | CLN3 | COL5A1 | CORO1A | CORO1B | CORO7 | CSK | CTGF | CTHRC1 | CUL3 | CXCL12 | CXCR4 | DCHS1 | DGKZ | DOCK1 | EFNA1 | ELMO1 | ELMO2 | ELMO3 | EMP2 | ENG | ENPEP | EPHA2 | EPHA3 | EPHB3 | ERG | FAM83D | FAT1 | FERMT2 | FGFR1 | FGFR4 | FLT1 | FMNL3 | FN1 | FNDC3B | FOXC1 | FSCN1 | FUT8 | FZD2 | GAB2 | GAS6 | GFRA1 | GPC6 | GSK3A | GSK3B | HBEGF | HES1 | HOXA5 | IL12B | ITGA4 | ITGA7 | ITGAV | ITGB1 | ITGB1B | JAM3 | KDR | LAMA5 | LAMB1 | LAMC1 | LCP1 | MDK | MET | MMP14 | MMP2 | MYO18A | NANOS1 | NFATC2 | NODAL | NOX1 | NRP1 | NUP62 | PAFAH1B1 | PAK4 | PALLD | PARP9 | PDGFRA | PDGFRB | PDPK1 | PIK3CB | PIP5K1A | PLCG1 | PODXL | PPP1R9B | PRPF40A | PSTPIP2 | PTEN | PTPRF | PTPRK | PVR | RAB1A | RELN | RHBDF1 | S1PR1 | SCRIB | SCYL3 | SEMA3AA | SH3BP1 | SH3KBP1 | SIRPA | SIX2 | SLC9A1 | SNAI1 | SNAI2 | SORL1 | SRC | SRGAP1 | SSTR4 | ST14 | STRIP2 | TGFB1 | TGFB2 | TGFBR2 | TGFBR3 | THBS1 | TIAM1 | TNFAIP1 | TNS3 | TREM1 | VAV2 | VAV3 | VEGFA | VTN | WNT11 | WNT4 | WNT5A | WWC1
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13. Benzo(a)pyrene DNA damage response, detection of DNA damage Phenolphthalein | POR Phenolphthalein inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage]] 1: Mus musculus Liver
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
14. Benzo(a)pyrene norepinephrine biosynthetic process Sulpiride Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased norepinephrine biosynthetic process] 1: Rattus norvegicus Hypothalamus
6 genes: ATP7A | EPAS1 | GATA3 | INSM1 | KL | TH
1
15. Benzo(a)pyrene positive regulation of intracellular estrogen receptor signaling pathway Benzo(a)pyrene results in increased positive regulation of intracellular estrogen receptor signaling pathway 1: Homo sapiens Osteoblasts | Cell Line, Tumor
10 genes: AR | FOXA1 | FSHR | KMT2D | MED1 | NCOA3 | PAK1 | PARP1 | SKP2 | YAP1
1
16. Benzo(a)pyrene cell cycle Tretinoin Tretinoin inhibits the reaction [Benzo(a)pyrene results in increased cell cycle] 1: Homo sapiens Embryo, Mammalian | Lung | Fibroblasts | Cells, Cultured
451 genes: ABRAXAS2 | AHCTF1 | AHR | AJUBA | ANAPC1 | ANAPC16 | ANAPC4 | ANAPC5 | ANAPC7 | ANKLE2 | ANKRD53 | ANLN | APPL2 | ARF6 | ARHGEF2 | ARL3 | ARL8A | ARPP19 | ASPM | ATM | AURKA | AURKB | AVPI1 | BABAM2 | BANP | BCCIP | BECN1 | BEX2 | BIN3 | BIRC5 | BIRC6 | BLCAP | BOD1 | BRCA1 | BRCA2 | BRCC3 | BUB1 | BUB1B | BUB3 | CABLES1 | CABLES2 | CAMK1 | CCAR1 | CCDC124 | CCNA1 | CCNA2 | CCNB1 | CCNB2 | CCND1 | CCND2 | CCND3 | CCNDBP1 | CCNE1 | CCNE2 | CCNF | CCNG1 | CCNG2 | CCNK | CCNO | CCNY | CCPG1 | CD2AP | CDC123 | CDC14A | CDC14B | CDC16 | CDC20 | CDC25A | CDC25B | CDC25C | CDC27 | CDC34 | CDC42 | CDC45 | CDC5L | CDC6 | CDC7 | CDC73 | CDCA2 | CDCA3 | CDCA5 | CDCA8 | CDK1 | CDK14 | CDK2 | CDK20 | CDK4 | CDK6 | CDKN1A | CDKN1B | CDKN1C | CDKN2A | CDKN2B | CDKN2C | CDKN2D | CDKN3 | CDT1 | CENPE | CENPT | CENPV | CEP131 | CEP164 | CEP55 | CEP63 | CETN1 | CETN2 | CETN3 | CGREF1 | CHAF1B | CHEK1 | CHEK2 | CHMP3 | CHTF18 | CIB1 | CIT | CKAP2 | CKS1B | CKS2 | CLASP1 | CLASP2 | CLSPN | CLTA | CLTC | CROCC | CSNK1A1 | CSNK2A2 | CTCFL | CTDP1 | CUL4B | CUZD1 | CYLD | DAB2IP | DBF4 | DDIAS | DDIT3 | DIS3L2 | DLGAP5 | DMC1 | DMTF1 | DSN1 | DUSP1 | DYNC1H1 | DYNLT3 | E2F1 | E2F2 | E2F4 | E2F6 | E2F7 | E2F8 | E4F1 | ECT2 | EID1 | EIF2AK4 | ENSA | EPB41 | EPB41L2 | ERCC6L | ERH | ESCO2 | EVI5 | FAM83D | FANCD2 | FANCI | FBXL7 | FBXO31 | FBXO5 | FIGN | FOXM1 | FOXN3 | FOXO4 | FZR1 | GADD45A | GMNC | GMNN | GNAI1 | GOLGA2 | GPER1 | GPSM2 | H2AFX | HACE1 | HAUS1 | HAUS2 | HAUS4 | HAUS6 | HAUS7 | HAUS8 | HCFC1 | HELLS | HEPACAM | HMCN1 | HMGA2 | HNRNPU | IKZF1 | INCENP | ING4 | INSM1 | KAT2B | KCTD11 | KDM8 | KHDRBS1 | KIF11 | KIF18B | KIF23 | KIF2C | KLHDC8B | KLHL13 | KLHL21 | KLHL42 | KLK10 | KMT5A | KNSTRN | KNTC1 | KRT18 | LATS2 | LIG1 | LIG4 | LIN54 | LIN9 | LRRCC1 | LZTS2 | LZTS2A | MAD1L1 | MAD2L1 | MAD2L2 | MAEA | MAP3K20 | MAP3K8 | MAP9 | MAPK1 | MAPK12 | MAPK13 | MAPK3 | MAPK4 | MAPK7 | MAPRE2 | MARK4 | MASTL | MCM2 | MCM3 | MCM4 | MCM5 | MCM6 | MCM7 | MCM8 | MDC1 | MELK | MICAL3 | MIS18A | MKI67 | MLF1 | MLH1 | MNAT1 | MRPL41 | MSH2 | MTBP | MTUS1 | MYOG | NAE1 | NASP | NBN | NCAPD2 | NCAPG2 | NCAPH | NDC80 | NDE1 | NEDD1 | NEDD9 | NEK1 | NEK11 | NEK2 | NEK4 | NEK6 | NEK8 | NEK9 | NIPBLA | NR3C1 | NSMCE2 | NUDC | NUF2 | NUP37 | NUP43 | NUSAP1 | OIP5 | PAFAH1B1 | PAK4 | PARD3 | PARD3B | PARD6A | PARD6B | PDCD2L | PDCD6IP | PDS5B | PELO | PHF13 | PHF8 | PIM1 | PIM2 | PIM3 | PIMREG | PIN1 | PKMYT1 | PKN2 | PLK1 | PLK3 | PLK5 | PMP22 | PPM1D | PPP1CA | PPP1CB | PPP1CC | PPP6C | PRC1 | PRKCD | PRKCE | PRPF40A | PRR5 | PSME3 | PSRC1 | PTP4A1 | PTTG1 | PYHIN1 | RAB11A | RAB11FIP3 | RAB11FIP4 | RAB11FIP4A | RABGAP1L | RACGAP1 | RACK1 | RAD17 | RAD50 | RALA | RALB | RAN | RASSF1 | RASSF2 | RASSF4 | RB1 | RB1CC1 | RBBP8 | RBL1 | RBM38 | RCC2 | REEP3 | RGCC | RGS2 | RIOK2 | RPS3 | RPS6KA1 | RPS6KA3 | RUVBL1 | S100A6 | SAC3D1 | SAPCD2 | SDE2 | SEH1L | SEPT10 | SEPT11 | SEPT3 | SEPT4 | SEPT5 | SEPT6 | SEPT9 | SETDB2 | SGO1 | SGSM3 | SIAH1A | SIAH2 | SIK1 | SIRT2 | SKA2 | SMARCB1 | SMC1A | SMC1B | SMC2 | SMC3 | SMC5 | SNX18 | SPAG5 | SPAG8 | SPAST | SPC24 | SPC25 | SPDL1 | SPIN1 | SRC | STAG1 | STAG2 | STAG3 | STARD13 | STEAP3 | STK10 | STOX1 | SUV39H1 | SYCP3 | TACC1 | TACC3 | TAF1 | TBRG1 | TENT4B | TERF2 | TFDP1 | TFDP2 | THAP1 | TIMELESS | TIPIN | TLK1 | TMPRSS11A | TP53 | TP53BP2 | TP63 | TPR | TPX2 | TREX1 | TRIM21 | TRIOBP | TRNP1 | TRP53 | TRP73 | TSPYL2 | TTC28 | TTK | TXNIP | TXNL4A | UBA3 | UBE2C | UBE2I | UHRF1 | UHRF2 | USP16 | USP2 | USP3 | USP39 | USP8 | USP9X | VASH1 | VCP | VPS4B | VRK1 | WASL | WDR6 | WEE1 | WTAP | ZC3HC1 | ZFP207 | ZFP385A | ZFP830 | ZFYVE19 | ZFYVE26 | ZW10 | ZWILCH | ZWINT
1
17. Benzo(a)pyrene positive regulation of heart rate Benzo(a)pyrene results in decreased positive regulation of heart rate 1: Danio rerio Heart
19 genes: ADA | ADM | ADRB1 | ATP2A2 | AVPR1A | CRHR2 | EDN1 | EDN2 | GCH1 | HEY2 | HRC | KCNQ1 | NPPA | PROC | RYR2 | SCN3B | SLC1A1 | TACR3 | TRPM4
1
18. Benzo(a)pyrene DNA methylation Benzo(a)pyrene affects DNA methylation 1: Danio rerio Embryo, Nonmammalian
25 genes: ATRX | BAZ2A | BMI1 | CTCF | DMAP1 | DNMT1 | DNMT3A | DNMT3AA | DNMT3AB | DNMT3B | DNMT3BA | DNMT3BB.1 | DNMT3BB.2 | DNMT3L | EHMT1 | EZH2 | FOS | GATAD2A | HELLS | HEMK1 | KMT2A | MGMT | MT2 | MTR | PPM1D
1
19. Benzo(a)pyrene chromosome segregation CYP1B1 [CYP1B1 protein results in increased susceptibility to Benzo(a)pyrene] which results in increased chromosome segregation 1: Homo sapiens Lung | Fibroblasts | Cell Line
60 genes: ABRAXAS2 | ARL8A | AURKB | BIRC5 | BRCA1 | BRD4 | BUB1 | BUB3 | CDCA2 | CDK5RAP2 | CDT1 | CENPE | CENPF | CENPH | CENPT | CEP85 | CIAO1 | CTCF | DDX3X | DSN1 | ERCC2 | ESCO2 | ESPL1 | FAM96B | INCENP | KIF2C | KNSTRN | MARS | MIS18A | MLH1 | NDC80 | NEK2 | NEK6 | NR3C1 | NTMT1 | NUF2 | NUP37 | NUP43 | PHF13 | PTTG1 | REC8 | RIOK3 | RPS3 | SEH1L | SETDB2 | SGO1 | SKA2 | SLC25A5 | SPAG5 | SPC25 | SRPK1 | STAG1 | STAG2 | STAG3 | TOP2A | TOP3B | UBE2I | USP9X | UVRAG | ZFP207
1
20. Benzo(a)pyrene nitric oxide biosynthetic process Benzo(a)pyrene results in increased nitric oxide biosynthetic process 1: Homo sapiens Keratinocytes | Cell Line
16 genes: AKT1 | ARG2 | CYP1B1 | DDAH1 | DDAH2 | GCH1 | GCHFR | HSP90AA1 | NOS1 | NOS2 | NOS3 | NQO1 | P2RX4 | RORA | SLC7A2 | SPR
1
21. Benzo(a)pyrene DNA damage response, detection of DNA damage ARNT ARNT protein affects the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] 1: Mus musculus Liver | Cell Line, Tumor
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
22. Benzo(a)pyrene cell death Curcumin Curcumin inhibits the reaction [Benzo(a)pyrene results in increased cell death] 1: Homo sapiens Lung | Epithelial Cells | Cell Line
36 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | CACNA1A | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | EMP3 | FAF1 | FBXO18 | FOSL2 | GSDME | GZMM | HMOX1 | KLK8 | MAP3K10 | MAP3K11 | MAP3K20 | NDOR1 | NUP62 | OPTN | PARP4 | PMP22 | PNPLA8 | PRKD2 | PTGER3 | SNCAIP | SUSD6 | TGFB2 | TRAF6 | VAPA
1
23. Benzo(a)pyrene DNA damage response, detection of DNA damage benzo(a)pyrene-DNA adduct [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] which results in increased abundance of benzo(a)pyrene-DNA adduct 1: Mus musculus Pulmonary Alveoli | Cell Line
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
24. Benzo(a)pyrene citrate transport Benzo(a)pyrene results in increased citrate transport 1: Rattus norvegicus Hepatocytes | Cells, Cultured
3 genes: SFXN5 | SLC13A3 | SLC13A5
1
25. Benzo(a)pyrene reactive oxygen species biosynthetic process cyanidin cyanidin inhibits the reaction [Benzo(a)pyrene results in increased reactive oxygen species biosynthetic process] 1: Mus musculus Fibroblasts | Cell Line, Transformed 1 gene: GBF1 1
26. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 1: Mus musculus Liver
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
2
27. Benzo(a)pyrene reactive oxygen species biosynthetic process Quercetin Quercetin inhibits the reaction [Benzo(a)pyrene results in increased reactive oxygen species biosynthetic process] 1: Mus musculus Fibroblasts | Cell Line, Transformed 1 gene: GBF1 1
28. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Lung | Epithelial Cells | Cell Line, Tumor
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
29. Benzo(a)pyrene plasma membrane fusion Benzo(a)pyrene results in increased plasma membrane fusion 1: Homo sapiens Trophoblasts | Cell Line, Tumor
2 genes: ERVFRD-1 | NSF
1
30. Benzo(a)pyrene glutathione peroxidase activity Benzo(a)pyrene results in decreased glutathione peroxidase activity 1: Homo sapiens Erythrocytes
24 genes: GPX1 | GPX1B | GPX2 | GPX3 | GPX4 | GPX4A | GPX4B | GPX5 | GPX7 | GPX8 | GSTA1 | GSTK1 | GSTM2 | GSTM7 | GSTP1 | GSTP2 | GSTS1 | GSTT1 | GSTT2 | GSTZ1 | MGST1 | MGST2 | MGST3 | PRDX6
1
31. Benzo(a)pyrene cellular pigment accumulation Lipofuscin [Benzo(a)pyrene results in increased cellular pigment accumulation] which results in increased abundance of Lipofuscin 1: Mytilus galloprovincialis Digestive System | Exocrine Glands 1 gene: SHROOM3 1
32. Benzo(a)pyrene positive regulation of p38MAPK cascade TNF Benzo(a)pyrene promotes the reaction [TNF protein results in increased positive regulation of p38MAPK cascade] 1: Rattus norvegicus Liver | Epithelial Cells | Cell Line
19 genes: ARHGEF2 | BMP2 | DHX15 | GADD45A | GADD45B | GADD45G | IL1B | MAP3K4 | MAP3K5 | MET | MINK1 | MIR181A1 | NCF1 | OPRK1 | PRMT1 | SASH1 | VEGFA | XDH | ZC3H12A
1
33. Benzo(a)pyrene DNA damage response, detection of DNA damage TP63 TP63 protein affects the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Hep G2 Cells
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
34. Benzo(a)pyrene trophoblast cell migration U 0126 U 0126 inhibits the reaction [Benzo(a)pyrene results in decreased trophoblast cell migration] 1: Homo sapiens Placenta | Cell Line, Transformed 1 gene: ITGB4 1
35. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Hepatocytes | Cell Line, Tumor
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
36. Benzo(a)pyrene histone H3-K4 dimethylation Benzo(a)pyrene results in decreased histone H3-K4 dimethylation 1: Mus musculus Liver 1 gene: KMT2A 1
37. Benzo(a)pyrene cellular response to 2,3,7,8-tetrachlorodibenzodioxine Benzo(a)pyrene results in increased cellular response to 2,3,7,8-tetrachlorodibenzodioxine 1: Rattus norvegicus Hepatocytes | Cell Line, Tumor
2 genes: AHR | PDE2A
1
38. Benzo(a)pyrene DNA damage response, detection of DNA damage 1-aminobenzotriazole | beta Carotene 1-aminobenzotriazole inhibits the reaction [beta Carotene affects the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage]] 1: Homo sapiens Lung | Cell Line, Tumor
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
39. Benzo(a)pyrene positive regulation of neuron apoptotic process Benzo(a)pyrene results in increased positive regulation of neuron apoptotic process 1: Danio rerio Diencephalon
65 genes: AGRN | AIFM1 | ATF2 | ATF4 | ATM | BAG1 | BAX | BBC3 | BCL2L11 | CASP2 | CASP3 | CASP6 | CASP9 | CCL3 | CDC34 | CDC42 | CDK5R1 | CTNNB1 | CTSZ | DDIT3 | EGR1 | EPHA7 | FAS | FASLG | FGFR3 | FOXO3 | GRIK5 | GSK3A | GSK3B | HDAC3 | HDAC4 | IL18 | IL1B | ITGA1 | JUN | KCNMA1 | MAP2K4 | MAP3K11 | MAPK8 | MYB | MYBL2 | NCF2 | NF1 | NQO1 | NQO2 | NR3C1 | OPTN | PAK3 | PAWR | PCSK9 | PIN1 | PITX3 | PMAIP1 | PRNP | PTPRF | RAPSN | SRPK2 | TFAP2A | TFAP2B | TGFB2 | TNF | TNFRSF1A | TP53 | TRP53 | UBE2M
1
40. Benzo(a)pyrene fatty acid biosynthetic process Benzo(a)pyrene affects fatty acid biosynthetic process 1: Mus musculus Macrophages | Cell Line
58 genes: ABCD3 | ACACA | ACACB | ACLY | ACSF3 | ACSL3 | ACSM1 | ACSM3 | BRCA1 | DEGS1 | ELOVL1 | ELOVL3 | ELOVL4A | ELOVL5 | ELOVL6 | ELOVL7 | ELOVL7B | FA2H | FADS1 | FADS2 | FADS3 | FADS6 | FAM213B | FASN | HACD1 | HACD2 | HACD3 | HACD4 | HPGDS | HSD17B12 | LIPC | LPL | MCAT | MGLL | MLYCD | NDUFAB1 | NR1H3 | PECR | PLA2G1B | PRKAA2 | PRKAB1 | PRKAB2 | PRKAG1 | PRKAG2 | PRKAG3 | PTGDS | PTGES | PTGES2 | PTGES3 | PTGIS | PTGS1 | PTGS2 | SCD | SCD1 | SCD2 | TBXAS1 | TECR | XBP1
1
41. Benzo(a)pyrene xenobiotic metabolic process Benzo(a)pyrene results in increased xenobiotic metabolic process 1: Homo sapiens Precursor Cells, B-Lymphoid | Cell Line
76 genes: ACSM1 | ACSM2B | ACY1 | ACY3 | AHR | AHRR | AIP | AKR1C1 | AKR1C12 | AKR1C13 | AKR7A3 | ALDH3A1 | AOC1 | AOC2 | AOC3 | AOX1 | ARNT | ARNT2 | BPHL | CBR3 | CES1 | CES2 | CES3 | CMBL | CYB5R3 | CYP1A2 | CYP1B1 | CYP26A1 | CYP26B1 | CYP2B10 | CYP2B6 | CYP2C19 | CYP2D6 | CYP2E1 | CYP2J2 | CYP2W1 | CYP3A4 | CYP3A5 | CYP3A7 | CYP46A1 | DPEP1 | EPHX1 | EPHX2 | FMO1 | FMO2 | FMO3 | GGT1 | GLYAT | GSTA4 | GSTM2 | GSTO2 | GSTP1 | HNF4A | HSP90AB1 | MARC1 | MGST1 | MGST2 | MGST3 | NAT1 | NAT2 | NCEH1 | NQO1 | NQO2 | NR1I2 | POR | PTGES3 | PTGS1 | RORA | RORC | S100A9 | SULT1A1 | SULT1A3 | SULT1B1 | UGT1A6 | UGT1A9 | UGT2B11
1
42. Benzo(a)pyrene positive regulation of cell cycle arrest Benzo(a)pyrene results in increased positive regulation of cell cycle arrest 1: Homo sapiens Lung | Epithelial Cells | Cell Line
27 genes: BRCA1 | CDK5R1 | CDKN2A | CRLF3 | DAB2IP | FAP | FOXO4 | GATA6 | HMGA2 | ID2 | INSM1 | MIR34A | MYBBP1A | MYOG | PKD2 | POU4F1 | PPP2R5B | RGCC | RIPOR2 | RPL23 | TGFB1 | TP53 | TP73 | TRP53 | TRP73 | UHRF2 | ZBTB17
1
43. Benzo(a)pyrene lipid biosynthetic process Benzo(a)pyrene results in increased lipid biosynthetic process 1: Rattus norvegicus Hepatocytes | Cells, Cultured
22 genes: ACLY | ACSL1 | ACSL4 | ACSS2 | AGMO | AGPS | CH25H | CLN8 | DCTN6 | FA2H | FASN | FDFT1 | GCG | GPAT4 | MSMO1 | PRKAA2 | PRPF19 | SC5D | SCD | SCD1 | SREBF1 | SREBF2
1
44. Benzo(a)pyrene vitamin E biosynthetic process Quercetin Quercetin inhibits the reaction [Benzo(a)pyrene results in decreased vitamin E biosynthetic process] 1: Mus musculus Lung 1 gene: PLTP 1
45. Benzo(a)pyrene negative regulation of androgen receptor activity Dihydrotestosterone [Benzo(a)pyrene results in increased negative regulation of androgen receptor activity] which results in decreased susceptibility to Dihydrotestosterone 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: HEYL 1
46. Benzo(a)pyrene cell proliferation Catechin Catechin inhibits the reaction [Benzo(a)pyrene results in increased cell proliferation] 1: Mus musculus Fibroblasts | Cell Line, Transformed
327 genes: ACE | ACHE | ADRA1B | ADRA1D | AKT1 | ALK | ALKBH3 | APPL2 | AR | AREG | ARHGEF1 | ASAH2 | ASCC3 | AURKB | AXIN2 | BAD | BAX | BCAR1 | BCAT1 | BCL2 | BCL2L1 | BIN1 | BMP4 | BOK | BOP1 | BRAT1 | BRCA2 | BST2 | BUB1 | BUB1B | BYSL | CBFA2T3 | CD160 | CD276 | CD34 | CD5 | CD70 | CD74 | CD81 | CDC14A | CDC16 | CDC25A | CDC25C | CDC27 | CDK1 | CDK4 | CDK5R1 | CDK5RAP3 | CDK9 | CDV3 | CENPF | CEP120 | CFB | CITED1 | CITED2 | CKLF | CKS1B | CKS2 | CLK1 | COL4A3BP | CREBBP | CREG1 | CSE1L | CSF1 | CSF1R | CSGALNACT1 | CSPG4 | CTNNB1 | CUL1 | CUL5 | CUZD1 | CXCL1 | CYP1A1 | CYR61 | DAB2 | DACH1 | DAZAP1 | DCTN2 | DDIT4 | DICER1 | DKC1 | DLG1 | DLGAP5 | DLX5 | DNPH1 | DTYMK | DUSP22 | E2F8 | E4F1 | ECD | EDNRA | EGFR | EMP1 | EMP2 | ENPEP | ENTPD5 | EPO | EPS15 | EPS8 | ERBB2 | ERCC1 | ERCC2 | EREG | ERG | ESRRB | EVI5 | FAM83D | FBXL7 | FER | FES | FGF1 | FGF13 | FGF16 | FGF18 | FGF2 | FOXC1 | FOXC2 | FPGS | FSCN1 | FURIN | GAS6 | GBX2 | GCG | GDNF | GFI1B | GH1 | GLUL | GMNC | GNL3 | GPC4 | GPX1 | GRPR | GSK3B | H3F3A | H3F3B | HDGF | HGF | HHEX | HLCS | HMGA2 | HOXB4 | HRAS | HTR1A | ID4 | IFNAR2 | IGF1 | IGFBP4 | IGSF8 | IL12B | IL15RA | IL18 | IL18RAP | IL1A | IL2RA | INSIG1 | INSL4 | IRF2 | IRS2 | ISG20 | ITGA2 | KDM1A | KHDRBS1 | KIF15 | KIF2C | KITLG | KLF10 | KRT16 | LAMA5 | LGI1 | LIG4 | LIPG | LRP1 | LY6E | LY86 | MAP2K1 | MAP3K11 | MAP3K2 | MAP3K20 | MAP4K1 | MAP7 | MAPRE2 | MAS1 | MATK | MCM10 | MCM7 | MDM4 | MELK | MET | MIA | MIF | MKI67 | MNAT1 | MORF4L1 | MOV10L1 | MRE11A | MT3 | MVP | MXD1 | MYB | MYC | MYH10 | NANOG | NASP | NBN | NCF1 | NEDD8 | NKX6-1 | NPY | NUDC | NUMB | NUPR1 | OCA2 | ORC1 | OSM | OTUD6B | PA2G4 | PAK4 | PCNA | PDAP1 | PDK1 | PDPN | PDS5B | PDXK | PDZK1 | PELO | PEMT | PES1 | PICALM | PIM1 | PIM2 | PLCE1 | PLK1 | POLA1 | PPARD | PRDX1 | PRKD1 | PRKDC | PRL | PSPHP1 | PTEN | PTGES3 | PTMA | PTPN6 | PURB | PURBB | RAF1 | RAP1B | RAPGEF3 | RASGRP4 | RBBP7 | RETNLB | RHBDF1 | ROS1 | RPL23A | RPL29 | RPS27 | RRN3 | SBDS | SCRIB | SDCBP2 | SERPINF1 | SHH | SIPA1 | SIX1 | SIX2 | SKI | SKP2 | SORL1 | SOX11 | SOX2 | SPHK2 | SRA1 | SRC | SRGAP2 | STAT3 | STAT4 | STIL | SYK | TACC1 | TACC3 | TBCK | TBX1 | TBX20 | TCF19 | TCF7L2 | TFDP1 | TGFB1 | TGFB2 | THOC6 | THPO | TNF | TNFRSF1B | TNFSF13B | TNFSF9 | TOP2A | TP53 | TP63 | TPT1 | TPX2 | TRAIP | TRP63 | TSPAN5 | TSPO | TXLNA | TXN | TXNRD1 | UBE2V2 | UBR5 | UCHL1 | UHRF1 | UHRF2 | USP13 | USP28 | USP8 | VEGFA | VEGFD | VPS25 | VPS36 | VTI1B | VTN | XRCC5 | YAP1 | YME1L1 | ZEB1 | ZFP36L1 | ZFP36L2 | ZPR1
1
47. Benzo(a)pyrene cell migration Benzo(a)pyrene results in increased cell migration 1: Homo sapiens Lung | Cell Line, Tumor
158 genes: ABI2 | ABP1 | ACVR1 | ADAM9 | ADAMTS12 | ADGRE2 | ADGRG1 | ANG | ARC | ARHGAP35 | ARPC5 | ATN1 | BAMBI | BCAR1 | BRAT1 | BTG1 | CARMIL1 | CARMIL2 | CCDC88A | CD151 | CD248 | CD24A | CD2AP | CD44 | CD47 | CD63 | CDC42BPB | CDH2 | CDH7 | CDK1 | CEACAM1 | CELF1 | CLASP2 | CLN3 | COL5A1 | CORO1A | CORO1B | CORO7 | CSK | CTGF | CTHRC1 | CUL3 | CXCL12 | CXCR4 | DCHS1 | DGKZ | DOCK1 | EFNA1 | ELMO1 | ELMO2 | ELMO3 | EMP2 | ENG | ENPEP | EPHA2 | EPHA3 | EPHB3 | ERG | FAM83D | FAT1 | FERMT2 | FGFR1 | FGFR4 | FLT1 | FMNL3 | FN1 | FNDC3B | FOXC1 | FSCN1 | FUT8 | FZD2 | GAB2 | GAS6 | GFRA1 | GPC6 | GSK3A | GSK3B | HBEGF | HES1 | HOXA5 | IL12B | ITGA4 | ITGA7 | ITGAV | ITGB1 | ITGB1B | JAM3 | KDR | LAMA5 | LAMB1 | LAMC1 | LCP1 | MDK | MET | MMP14 | MMP2 | MYO18A | NANOS1 | NFATC2 | NODAL | NOX1 | NRP1 | NUP62 | PAFAH1B1 | PAK4 | PALLD | PARP9 | PDGFRA | PDGFRB | PDPK1 | PIK3CB | PIP5K1A | PLCG1 | PODXL | PPP1R9B | PRPF40A | PSTPIP2 | PTEN | PTPRF | PTPRK | PVR | RAB1A | RELN | RHBDF1 | S1PR1 | SCRIB | SCYL3 | SEMA3AA | SH3BP1 | SH3KBP1 | SIRPA | SIX2 | SLC9A1 | SNAI1 | SNAI2 | SORL1 | SRC | SRGAP1 | SSTR4 | ST14 | STRIP2 | TGFB1 | TGFB2 | TGFBR2 | TGFBR3 | THBS1 | TIAM1 | TNFAIP1 | TNS3 | TREM1 | VAV2 | VAV3 | VEGFA | VTN | WNT11 | WNT4 | WNT5A | WWC1
1
48. Benzo(a)pyrene DNA damage response, detection of DNA damage ARNT ARNT protein affects the reaction [Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage] 1: Homo sapiens Hep G2 Cells
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
49. Benzo(a)pyrene DNA damage response, detection of DNA damage Benzo(a)pyrene results in increased DNA damage response, detection of DNA damage 1: Homo sapiens Caco-2 Cells
28 genes: CEP164 | CUL4A | CUL4B | DDB1 | DNAJA1 | DTL | HMGA2 | MRPS11 | MRPS26 | NEK1 | PARP1 | PCNA | POLD1 | POLD4 | RAD18 | RBX1 | RFC3 | RFC4 | RFC5 | RPA1 | RPA2 | RPS27A | RPS3 | SOX4 | UBA52 | UBC | UBE2B | USP1
1
50. Benzo(a)pyrene DNA modification benzo(a)pyrene N2-dG adduct [Benzo(a)pyrene results in increased DNA modification] which results in increased abundance of benzo(a)pyrene N2-dG adduct 1: Mytilus galloprovincialis Digestive System | Exocrine Glands
2 genes: CYP1B1 | GSTT1
1
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