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Chemical Bleomycin

1–50 of 194 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Bleomycin response to oxidative stress Bleomycin results in increased response to oxidative stress 1: Mus musculus Lung | Fibroblasts | Cell Line
28 genes: AKT1 | ALDH1A1 | BCL2 | CAT | CYCS | EPX | ERCC1 | GCLC | GPX1 | GSR | HMOX1 | KEAP1 | LCN2 | MMP2 | MMP9 | MPO | NFKB1 | NQO1 | PDLIM1 | PRDX2 | PRDX6 | PTGS2 | SIRT1 | SOD1 | SOD2 | SRXN1 | TP53 | TRP53
1
2. Bleomycin cell death honokiol Bleomycin promotes the reaction [honokiol results in increased cell death] 1: Homo sapiens MCF-7 Cells
2 genes: HMOX1 | TGFB2
1
3. Bleomycin positive regulation of NF-kappaB transcription factor activity Berberine Berberine inhibits the reaction [Bleomycin results in increased positive regulation of NF-kappaB transcription factor activity] 1: Rattus norvegicus Lung
13 genes: AGER | CAT | ICAM1 | IL1B | IL6 | KRAS | NFKB1 | NPM1 | RELA | S100A8 | TGFB1 | TNF | TRAF2
1
4. Bleomycin leukocyte migration involved in inflammatory response Grape Seed Extract Grape Seed Extract inhibits the reaction [Bleomycin results in increased leukocyte migration involved in inflammatory response] 1: Mus musculus Lung
2 genes: CCL2 | S100A8
1
5. Bleomycin leukocyte migration involved in inflammatory response N-((3-(aminomethyl)phenyl)methyl)ethanimidamide N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased leukocyte migration involved in inflammatory response] 1: Mus musculus Lung
2 genes: CCL2 | S100A8
1
6. Bleomycin leukocyte migration involved in inflammatory response Grape Seed Extract Grape Seed Extract inhibits the reaction [Bleomycin results in increased leukocyte migration involved in inflammatory response] 1: Mus musculus Lung | Macrophages
2 genes: CCL2 | S100A8
1
7. Bleomycin collagen biosynthetic process tripterine tripterine inhibits the reaction [Bleomycin results in increased collagen biosynthetic process] 1: Rattus norvegicus Lung
4 genes: ARG1 | COL1A1 | COL5A1 | SERPINH1
1
8. Bleomycin response to oxidative stress Berberine Berberine inhibits the reaction [Bleomycin results in increased response to oxidative stress] 1: Rattus norvegicus Lung
28 genes: AKT1 | ALDH1A1 | BCL2 | CAT | CYCS | EPX | ERCC1 | GCLC | GPX1 | GSR | HMOX1 | KEAP1 | LCN2 | MMP2 | MMP9 | MPO | NFKB1 | NQO1 | PDLIM1 | PRDX2 | PRDX6 | PTGS2 | SIRT1 | SOD1 | SOD2 | SRXN1 | TP53 | TRP53
1
9. Bleomycin DNA catabolic process Paraquat Paraquat promotes the reaction [Bleomycin results in increased DNA catabolic process]     1
10. Bleomycin DNA damage response, detection of DNA damage Bleomycin results in increased DNA damage response, detection of DNA damage 1: Homo sapiens HL-60 Cells 1 gene: PARP1 1
11. Bleomycin cell death honokiol Bleomycin affects the reaction [honokiol results in increased cell death] 1: Homo sapiens A549 Cells
2 genes: HMOX1 | TGFB2
1
12. Bleomycin apoptotic process Bleomycin results in increased apoptotic process 1: Mus musculus Bronchi | Epithelial Cells
45 genes: AKT1 | ATM | BAX | BCL2 | BIRC2 | BIRC5 | CASP3 | CASP8 | CASP9 | CCL6 | CHEK2 | COMP | CTSH | CYCS | DPEP1 | EIF5A | FASLG | GAS6 | GPX1 | GSN | HMOX1 | IFNG | IL1A | IL1B | LCN2 | MAPK1 | MAPK3 | NFKB1 | NFKBIA | NR3C1 | PARP1 | PML | POLB | RALB | S100A8 | SIRT1 | TF | TGFBR1 | TGFBR2 | TNF | TNFRSF1A | TNFRSF1B | TP53 | TRAF2 | TRP53
1
13. Bleomycin protein nitrosylation Bleomycin results in increased protein nitrosylation 1: Mus musculus Lung   1
14. Bleomycin lipid oxidation Phytochemicals Phytochemicals inhibits the reaction [Bleomycin results in increased lipid oxidation] 1: Rattus norvegicus Lung   1
15. Bleomycin protein modification process MMP3 MMP3 protein affects the reaction [Bleomycin results in increased protein modification process] 1: Mus musculus Lung 1 gene: PARP1 1
16. Bleomycin leukocyte migration involved in inflammatory response 12-(3-adamantan-1-ylureido)dodecanoic acid 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased leukocyte migration involved in inflammatory response] 1: Mus musculus Lung | Macrophages
2 genes: CCL2 | S100A8
1
17. Bleomycin leukocyte migration involved in inflammatory response 12-(3-adamantan-1-ylureido)dodecanoic acid 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased leukocyte migration involved in inflammatory response] 1: Mus musculus Lung | Lymphocytes
2 genes: CCL2 | S100A8
1
18. Bleomycin DNA catabolic process CYCS CYCS protein inhibits the reaction [Bleomycin results in increased DNA catabolic process]     1
19. Bleomycin cell proliferation Bleomycin results in increased cell proliferation 1: Mus musculus Lung | Fibroblasts
26 genes: ADRA1B | AKT1 | AREG | BAX | BCL2 | ELN | ERCC1 | FGF2 | GAS6 | GPX1 | GRPR | GSK3B | HGF | IL12B | IL1A | MIF | MYC | PDXK | RAP1B | TGFB1 | TGFB2 | TNF | TNFRSF1B | TP53 | VEGFA | XRCC5
1
20. Bleomycin positive regulation of DNA catabolic process Iron | positive regulation of reactive oxygen species biosynthetic process [[Iron co-treated with Bleomycin] results in increased positive regulation of reactive oxygen species biosynthetic process] which results in increased positive regulation of DNA catabolic process 1: Rattus norvegicus Liver | Cell Nucleus 1 gene: ATM 1
21. Bleomycin DNA modification 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one | 8-oxo-7-hydrodeoxyguanosine 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [[Bleomycin results in increased DNA modification] which results in increased abundance of 8-oxo-7-hydrodeoxyguanosine] 1: Mus musculus Lung | Epithelium   1
22. Bleomycin histamine biosynthetic process tripterine tripterine inhibits the reaction [Bleomycin results in increased histamine biosynthetic process] 1: Rattus norvegicus Lung   1
23. Bleomycin DNA modification 8-oxo-7-hydrodeoxyguanosine [Bleomycin results in increased DNA modification] which results in increased abundance of 8-oxo-7-hydrodeoxyguanosine 1: Mus musculus Lung | Epithelium   1
24. Bleomycin response to toxic substance Berberine Berberine inhibits the reaction [Bleomycin results in increased response to toxic substance] 1: Rattus norvegicus Lung
16 genes: BAX | BCL2 | BLMH | CAT | CCL3 | CDH1 | CDKN1A | CES1 | DNMT1 | FOS | GPX1 | MAPK1 | MAPK3 | NQO1 | PDXK | TGFBR1
1
25. Bleomycin positive regulation of superoxide dismutase activity Methylprednisolone Methylprednisolone inhibits the reaction [Bleomycin results in decreased positive regulation of superoxide dismutase activity] 1: Rattus norvegicus Lung 1 gene: TNF 1
26. Bleomycin leukocyte migration involved in inflammatory response Bleomycin results in increased leukocyte migration involved in inflammatory response 1: Mus musculus Lung | Lymphocytes
2 genes: CCL2 | S100A8
2
27. Bleomycin positive regulation of DNA catabolic process Iron | Reactive Oxygen Species [[Iron co-treated with Bleomycin] results in increased abundance of Reactive Oxygen Species] which results in increased positive regulation of DNA catabolic process 1: Rattus norvegicus Liver | Cell Nucleus 1 gene: ATM 1
28. Bleomycin reactive oxygen species biosynthetic process Bleomycin results in increased reactive oxygen species biosynthetic process 1: Rattus norvegicus Lung   1
29. Bleomycin L-ascorbic acid biosynthetic process tripterine tripterine inhibits the reaction [Bleomycin results in decreased L-ascorbic acid biosynthetic process] 1: Rattus norvegicus Lung   1
30. Bleomycin DNA modification 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased DNA modification] 1: Mus musculus Lung | Epithelium   1
31. Bleomycin glutathione transferase activity Bleomycin results in decreased glutathione transferase activity 1: Rattus norvegicus Lung 1 gene: GSTM1 1
32. Bleomycin cell death Bleomycin results in increased cell death 1: Homo sapiens Skin | Cell Line, Tumor
2 genes: HMOX1 | TGFB2
1
33. Bleomycin cell death honokiol Bleomycin promotes the reaction [honokiol results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor
2 genes: HMOX1 | TGFB2
1
34. Bleomycin superoxide dismutase activity Bleomycin results in decreased superoxide dismutase activity 1: Rattus norvegicus Lung
3 genes: NQO1 | SOD1 | SOD2
1
35. Bleomycin positive regulation of apoptotic DNA fragmentation Bleomycin results in increased positive regulation of apoptotic DNA fragmentation 1: Rattus norvegicus Lymphocytes 1 gene: BAX 1
36. Bleomycin serotonin biosynthetic process Phytochemicals Phytochemicals inhibits the reaction [Bleomycin results in increased serotonin biosynthetic process] 1: Rattus norvegicus Lung   1
37. Bleomycin vitamin E biosynthetic process Bleomycin results in decreased vitamin E biosynthetic process 1: Rattus norvegicus Lung   1
38. Bleomycin DNA catabolic process NADP Bleomycin affects the reaction [NADP results in increased DNA catabolic process]     1
39. Bleomycin positive regulation of cell proliferation caffeic acid phenethyl ester | NFE2L2 NFE2L2 protein affects the reaction [caffeic acid phenethyl ester inhibits the reaction [Bleomycin affects positive regulation of cell proliferation]] 1: Mus musculus Lung | Fibroblasts | Cell Line
62 genes: ADAM17 | AKT1 | AREG | AVPR1A | BCL2 | BIRC5 | CALR | CDC20 | CRIP2 | CSF2 | CSF3 | CTGF | CTSH | CXCL10 | EDN1 | EIF5A | ETS1 | FASLG | FGF2 | FN1 | GATA3 | HBEGF | HGF | HIF1A | HMGB1 | HSP90AA1 | IFNG | IL12RB2 | IL1B | IL4 | IL6 | JUN | KRAS | LEP | LGALS3 | MAPK1 | MECP2 | MIR141 | MIR200B | MIR21 | MIR24-2 | MYC | NPM1 | PLAU | PTGS2 | RELA | S1PR1 | S1PR3 | SFRP1 | SIRT1 | SLC25A5 | TGFB1 | TGFB2 | TGFB3 | TGFBR1 | TGFBR2 | THRB | TIMP1 | TNC | TNF | TSHR | VEGFA
1
40. Bleomycin collagen biosynthetic process Bleomycin results in increased collagen biosynthetic process 2: Mus musculus | Rattus norvegicus Lung
4 genes: ARG1 | COL1A1 | COL5A1 | SERPINH1
2
41. Bleomycin leukocyte migration involved in inflammatory response Dexamethasone Dexamethasone inhibits the reaction [Bleomycin results in increased leukocyte migration involved in inflammatory response] 1: Mus musculus Lung | Neutrophils
2 genes: CCL2 | S100A8
2
42. Bleomycin positive regulation of myofibroblast differentiation Bleomycin results in increased positive regulation of myofibroblast differentiation 1: Rattus norvegicus Lung
2 genes: MIR21 | PARP1
1
43. Bleomycin leukocyte chemotaxis involved in inflammatory response Bleomycin results in increased leukocyte chemotaxis involved in inflammatory response 1: Mus musculus Lung   1
44. Bleomycin positive regulation of lung goblet cell differentiation 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased positive regulation of lung goblet cell differentiation] 1: Mus musculus Lung | Epithelium 1 gene: IL13 1
45. Bleomycin reactive oxygen species biosynthetic process Polyphenols Polyphenols inhibits the reaction [Bleomycin results in increased reactive oxygen species biosynthetic process] 1: Homo sapiens Cervix Uteri | Cell Line, Tumor   1
46. Bleomycin lipid catabolic process tripterine tripterine inhibits the reaction [Bleomycin results in increased lipid catabolic process] 1: Rattus norvegicus Lung
2 genes: BSCL2 | PRDX6
1
47. Bleomycin positive regulation of collagen biosynthetic process Bleomycin affects positive regulation of collagen biosynthetic process 1: Mus musculus Lung | Fibroblasts | Cell Line
6 genes: CCL2 | CTGF | SERPINE1 | TGFB1 | TGFB3 | VIM
1
48. Bleomycin leukocyte migration involved in inflammatory response Bleomycin results in increased leukocyte migration involved in inflammatory response 1: Mus musculus Pulmonary Alveoli
2 genes: CCL2 | S100A8
1
49. Bleomycin positive regulation of collagen biosynthetic process Bleomycin results in increased positive regulation of collagen biosynthetic process 1: Mus musculus Skin
6 genes: CCL2 | CTGF | SERPINE1 | TGFB1 | TGFB3 | VIM
1
50. Bleomycin DNA catabolic process Nitrofurantoin Nitrofurantoin promotes the reaction [Bleomycin results in increased DNA catabolic process]     1
1–50 of 194 results.