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Chemical Carbon Tetrachloride

1–50 of 538 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Carbon Tetrachloride collagen metabolic process Carbon Tetrachloride affects collagen metabolic process 1: Rattus norvegicus Liver
7 genes: HIF1A | ID1 | MIR21 | P2RX7 | P3H1 | TGFBR3 | TNXB
1
2. Carbon Tetrachloride extracellular matrix organization puerarin puerarin inhibits the reaction [Carbon Tetrachloride affects extracellular matrix organization] 1: Rattus norvegicus Liver
108 genes: ABI3BP | ADAM12 | ADAM15 | ADAM19 | ADAMTSL4 | AGT | APBB1 | APBB2 | APLP2 | APP | ATP7A | BGN | CCDC80 | CD44 | CD47 | CDH1 | COL11A1 | COL14A1 | COL18A1 | COL1A1 | COL1A2 | COL3A1 | COL4A1 | COL4A2 | COL4A5 | COL5A1 | COL5A2 | COL6A3 | COL8A1 | CRISPLD2 | DAG1 | DCN | DDR1 | ELF3 | ELN | ERO1L | F11R | FBLN2 | FBLN5 | FBN1 | FGA | FGB | FGF2 | FGG | FN1 | FOXF1 | GFAP | GPC4 | HSPG2 | ICAM1 | ICAM2 | ITGA1 | ITGA2 | ITGA3 | ITGA7 | ITGA8 | ITGAM | ITGAV | ITGB1 | ITGB2 | ITGB4 | ITGB5 | ITGB6 | ITGB8 | JAM3 | KDR | LAMA1 | LAMA2 | LAMA3 | LAMA5 | LAMB2 | LGALS3 | LUM | MFAP5 | MMP1 | MMP11 | MMP9 | NCAN | NID1 | NID2 | OLFML2B | PDGFA | PDGFB | PDGFRA | PECAM1 | POSTN | PXDN | RECK | SERAC1 | SERPINE1 | SMOC2 | SOX9 | SPARC | SPP1 | TGFB2 | TGFBI | THBS1 | THBS2 | THBS3 | TMPRSS6 | TNC | TNF | TNXB | TTR | VCAM1 | VCAN | VTN | VWF
1
3. Carbon Tetrachloride detection of oxidative stress Carbon Tetrachloride results in increased detection of oxidative stress 1: Mus musculus Liver 1 gene: ADIPOQ 2
4. Carbon Tetrachloride membrane lipid catabolic process Glutathione Glutathione inhibits the reaction [Carbon Tetrachloride results in increased membrane lipid catabolic process] 1: Rattus norvegicus Liver | Microsomes
2 genes: CYP1B1 | SMPDL3B
1
5. Carbon Tetrachloride detection of oxidative stress Drugs, Chinese Herbal Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased detection of oxidative stress] 1: Mus musculus Liver 1 gene: ADIPOQ 1
6. Carbon Tetrachloride nitric oxide biosynthetic process Carbon Tetrachloride results in increased nitric oxide biosynthetic process 1: Mus musculus Serum
10 genes: AKT1 | CYP1B1 | DDAH1 | GCH1 | GCHFR | NOS1 | NOS2 | NOS3 | NQO1 | RORA
1
7. Carbon Tetrachloride ceramide biosynthetic process Rutin Rutin inhibits the reaction [Carbon Tetrachloride results in increased ceramide biosynthetic process] 1: Mus musculus Kidney
6 genes: CERS6 | CLN8 | P2RX7 | SGMS1 | SMPD2 | SPTLC2
1
8. Carbon Tetrachloride D-alanine:2-oxoglutarate aminotransferase activity Carbon Tetrachloride results in increased D-alanine:2-oxoglutarate aminotransferase activity 1: Rattus norvegicus Liver   1
9. Carbon Tetrachloride urate biosynthetic process Rutin Rutin inhibits the reaction [Carbon Tetrachloride results in increased urate biosynthetic process] 1: Mus musculus Serum
2 genes: PRPS1 | XDH
1
10. Carbon Tetrachloride vasodilation Acetylcholine Carbon Tetrachloride inhibits the reaction [Acetylcholine affects vasodilation] 1: Rattus norvegicus Liver
18 genes: ADORA2A | AGT | AGTR2 | ALB | APOE | BDKRB2 | CPS1 | EDNRB | GCH1 | GPX1 | ITGA1 | KCNMA1 | KNG1 | NOS1 | NOS3 | PDE5A | SOD2 | VAMP2
1
11. Carbon Tetrachloride nitric oxide biosynthetic process bifendate bifendate inhibits the reaction [Carbon Tetrachloride results in increased nitric oxide biosynthetic process] 1: Mus musculus Liver
10 genes: AKT1 | CYP1B1 | DDAH1 | GCH1 | GCHFR | NOS1 | NOS2 | NOS3 | NQO1 | RORA
1
12. Carbon Tetrachloride gluconeogenesis Carbon Tetrachloride results in decreased gluconeogenesis 1: Mus musculus Hepatic Veins | Plasma
21 genes: ALDOA | ATF3 | ATF4 | CAR5A | CRY1 | ENO2 | ENO3 | FBP2 | G6PC | GAPDH | GOT1 | PC | PCK1 | PCK2 | PER2 | PPARGC1A | RBP4 | SDS | SLC25A10 | SLC25A11 | SLC37A4
1
13. Carbon Tetrachloride response to toxic substance Flavonoids Flavonoids inhibits the reaction [Carbon Tetrachloride affects response to toxic substance] 1: Mus musculus Liver
76 genes: ABCB4 | ADAMTS13 | AHR | ALAD | ARNT2 | ASL | ASNS | ASS1 | ATF4 | BAX | BCL2 | BDH1 | BPHL | CASP1 | CAT | CCL3 | CCL4 | CCL5 | CCNB1 | CDH1 | CDK1 | CDK2 | CDK4 | CDKN1A | CES1D | CHKA | CPS1 | CST3 | CYP1A1 | CYP1B1 | CYP2F2 | DDC | DDIT3 | DHX15 | DNMT1 | DNMT3A | DRD2 | EIF2AK2 | EPHX1 | EPHX2 | FAS | FGA | FOS | GABRB1 | GPX1 | GRIA1 | GSTP1 | GUCY2C | HDAC6 | HTR1D | INMT | MAOB | MAPK1 | MAPK3 | MAPK9 | MGMT | NQO1 | NUPR1 | PDGFRB | PEBP1 | PON1 | RAD51 | RELN | SDC1 | SLC22A8 | SLC30A4 | SLC7A11 | SLC7A8 | SRSF9 | STAR | TGFBR1 | TK1 | TLR2 | TLR4 | TTPA | TYMS
1
14. Carbon Tetrachloride lipid oxidation Aspirin | Malondialdehyde Aspirin inhibits the reaction [[Carbon Tetrachloride results in increased lipid oxidation] which results in increased abundance of Malondialdehyde] 1: Rattus norvegicus Liver 1 gene: PLA2G7 1
15. Carbon Tetrachloride response to toxic substance Carbon Tetrachloride affects response to toxic substance 2: Mus musculus | Rattus norvegicus Liver
76 genes: ABCB4 | ADAMTS13 | AHR | ALAD | ARNT2 | ASL | ASNS | ASS1 | ATF4 | BAX | BCL2 | BDH1 | BPHL | CASP1 | CAT | CCL3 | CCL4 | CCL5 | CCNB1 | CDH1 | CDK1 | CDK2 | CDK4 | CDKN1A | CES1D | CHKA | CPS1 | CST3 | CYP1A1 | CYP1B1 | CYP2F2 | DDC | DDIT3 | DHX15 | DNMT1 | DNMT3A | DRD2 | EIF2AK2 | EPHX1 | EPHX2 | FAS | FGA | FOS | GABRB1 | GPX1 | GRIA1 | GSTP1 | GUCY2C | HDAC6 | HTR1D | INMT | MAOB | MAPK1 | MAPK3 | MAPK9 | MGMT | NQO1 | NUPR1 | PDGFRB | PEBP1 | PON1 | RAD51 | RELN | SDC1 | SLC22A8 | SLC30A4 | SLC7A11 | SLC7A8 | SRSF9 | STAR | TGFBR1 | TK1 | TLR2 | TLR4 | TTPA | TYMS
2
16. Carbon Tetrachloride hepatocyte differentiation Ascorbic Acid | Butyric Acid | Dexamethasone | Dimethyl Sulfoxide | EGF | HGF | L-aspartate:2-oxoglutarate aminotransferase activity | Niacinamide | Oncostatin M [[EGF protein co-treated with Oncostatin M co-treated with Dexamethasone co-treated with Niacinamide co-treated with Ascorbic Acid] affects the reaction [[HGF protein co-treated with Dimethyl Sulfoxide co-treated with Butyric Acid] results in increased hepatocyte differentiation]] affects the reaction [Carbon Tetrachloride affects L-aspartate:2-oxoglutarate aminotransferase activity] 1: Mus musculus Embryonic Stem Cells
9 genes: CPS1 | CYP1A1 | E2F7 | HNF4A | ITGA2 | MIR122 | PCK1 | PCK2 | PROX1
1
17. Carbon Tetrachloride glutathione metabolic process Glutathione [Carbon Tetrachloride results in decreased glutathione metabolic process] which results in decreased abundance of Glutathione 1: Rattus norvegicus Kidney
33 genes: CTH | DPEP1 | ETHE1 | G6PDX | GCLC | GCLM | GGT1 | GLO1 | GPX1 | GSR | GSTA1 | GSTA2 | GSTA3 | GSTA4 | GSTK1 | GSTM1 | GSTM2 | GSTM3 | GSTM4 | GSTM5 | GSTM7 | GSTP1 | GSTT1 | GSTT2 | GSTT3 | GSTZ1 | HBB | MGST1 | NAT8 | OPLAH | SOD1 | SOD2 | TXNRD3
1
18. Carbon Tetrachloride histone H3 acetylation Carbon Tetrachloride results in decreased histone H3 acetylation 1: Mus musculus Liver
3 genes: CHM | JADE1 | JADE2
1
19. Carbon Tetrachloride membrane lipid catabolic process Disulfiram Disulfiram inhibits the reaction [Carbon Tetrachloride results in increased membrane lipid catabolic process] 1: Rattus norvegicus Hepatocytes | Cells, Cultured
2 genes: CYP1B1 | SMPDL3B
1
20. Carbon Tetrachloride glutamate biosynthetic process Carbon Tetrachloride results in increased glutamate biosynthetic process 1: Mus musculus Hepatocytes | Cells, Cultured
4 genes: GLS | GLUD1 | GOT1 | SLC1A3
1
21. Carbon Tetrachloride glutamate biosynthetic process Carbon Tetrachloride results in increased glutamate biosynthetic process 1: Mus musculus Portal Vein | Plasma
4 genes: GLS | GLUD1 | GOT1 | SLC1A3
1
22. Carbon Tetrachloride lipid catabolic process Silymarin Silymarin inhibits the reaction [Carbon Tetrachloride results in increased lipid catabolic process] 1: Mus musculus Liver
33 genes: ACAP1 | ADORA1 | AKR1D1 | APOA4 | APOB | APOC2 | APOC3 | ASPG | CES1D | CYP39A1 | DAGLA | ENPP2 | IRS1 | LIPC | LPL | NCEH1 | NEU3 | PAFAH2 | PCK1 | PCK2 | PLA1A | PLA2G12A | PLA2G16 | PLA2G4A | PLA2G7 | PLCD1 | PLCG2 | PNLIPRP1 | PPT1 | PRDX6 | RAB7A | SMPDL3B | TBL1XR1
1
23. Carbon Tetrachloride nitric-oxide synthase biosynthetic process Carbon Tetrachloride results in increased nitric-oxide synthase biosynthetic process 1: Mus musculus Liver   1
24. Carbon Tetrachloride membrane lipid catabolic process Vitamin E Vitamin E inhibits the reaction [Carbon Tetrachloride results in increased membrane lipid catabolic process] 1: Rattus norvegicus Liver
2 genes: CYP1B1 | SMPDL3B
1
25. Carbon Tetrachloride glutathione metabolic process Glutathione | Lipids | sesamol Lipids promotes the reaction [sesamol inhibits the reaction [[Carbon Tetrachloride affects glutathione metabolic process] which results in decreased abundance of Glutathione]] 1: Rattus norvegicus Liver
33 genes: CTH | DPEP1 | ETHE1 | G6PDX | GCLC | GCLM | GGT1 | GLO1 | GPX1 | GSR | GSTA1 | GSTA2 | GSTA3 | GSTA4 | GSTK1 | GSTM1 | GSTM2 | GSTM3 | GSTM4 | GSTM5 | GSTM7 | GSTP1 | GSTT1 | GSTT2 | GSTT3 | GSTZ1 | HBB | MGST1 | NAT8 | OPLAH | SOD1 | SOD2 | TXNRD3
1
26. Carbon Tetrachloride mitochondrial DNA replication Carbon Tetrachloride results in increased mitochondrial DNA replication 1: Rattus norvegicus Liver
2 genes: SLC25A16 | TFAM
1
27. Carbon Tetrachloride glutathione peroxidase activity Carbon Tetrachloride results in decreased glutathione peroxidase activity 2: Mus musculus | Rattus norvegicus Liver
14 genes: GPX1 | GPX2 | GPX7 | GSTA1 | GSTK1 | GSTM2 | GSTM7 | GSTP1 | GSTT1 | GSTT2 | GSTZ1 | MGST1 | MGST3 | PRDX6
4
28. Carbon Tetrachloride activation of protein kinase B activity Carbon Tetrachloride results in increased activation of protein kinase B activity 1: Rattus norvegicus Hepatic Stellate Cells
15 genes: ADRA2A | ADRA2B | AKT1 | FGF1 | GAS6 | IGF1 | IL18 | ITGB1BP1 | MIR21 | PDGFB | PINK1 | PRKCZ | SRC | TXN | WNT5A
1
29. Carbon Tetrachloride glutathione biosynthetic process crocin crocin inhibits the reaction [Carbon Tetrachloride results in decreased glutathione biosynthetic process] 1: Rattus norvegicus Kidney
7 genes: CHAC1 | CHAC2 | GCLC | GCLM | GGT1 | GSS | OPLAH
1
30. Carbon Tetrachloride glutamine biosynthetic process Carbon Tetrachloride results in increased glutamine biosynthetic process 1: Mus musculus Heart | Blood 1 gene: GLUL 1
31. Carbon Tetrachloride glutathione peroxidase activity Diethylnitrosamine [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased glutathione peroxidase activity 1: Rattus norvegicus Liver
14 genes: GPX1 | GPX2 | GPX7 | GSTA1 | GSTK1 | GSTM2 | GSTM7 | GSTP1 | GSTT1 | GSTT2 | GSTZ1 | MGST1 | MGST3 | PRDX6
1
32. Carbon Tetrachloride leukocyte chemotaxis involved in inflammatory response NFE2L2 | tetramethylpyrazine NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased leukocyte chemotaxis involved in inflammatory response]] 1: Mus musculus Liver 1 gene: LBP 1
33. Carbon Tetrachloride positive regulation of collagen biosynthetic process Ibuprofen Ibuprofen inhibits the reaction [Carbon Tetrachloride results in increased positive regulation of collagen biosynthetic process] 1: Rattus norvegicus Liver
20 genes: ARRB2 | CCL2 | CREB3L1 | CTGF | ENG | F2 | F2R | HDAC2 | IL18 | ITGA2 | LTBP1 | PDGFB | PDGFRB | PRDX5 | SERPINE1 | SOX9 | TGFB1 | TGFB3 | VIM | WNT4
1
34. Carbon Tetrachloride apoptotic process Quercetin [Carbon Tetrachloride co-treated with Quercetin] results in increased apoptotic process 1: Rattus norvegicus Hepatic Stellate Cells
215 genes: AATK | ABL1 | ADAM15 | ADAMTSL4 | ADORA2A | AHR | AIMP1 | AIMP2 | AKT1 | APBB1 | APP | AQP2 | ARHGEF6 | ASAH2 | BAD | BAG3 | BAG4 | BAK1 | BAX | BCAP29 | BCL2 | BCL2A1A | BCL2L1 | BCL2L11 | BCL7C | BIK | BIRC2 | BIRC5 | BNIP3 | BRCA1 | BUB1 | BUB1B | C1QBP | CAAP1 | CADM1 | CASP1 | CASP12 | CASP2 | CASP3 | CASP8 | CASP9 | CCK | CCL6 | CD14 | CD5L | CDCA7 | CDK1 | CDK11B | CDKN2A | CFLAR | CHAC1 | CHEK2 | CIDEC | CKAP2 | CLPTM1L | CST3 | CTSH | CXCR4 | CYCS | DAB2IP | DAD1 | DAPK1 | DAXX | DDIT3 | DHCR24 | DLC1 | DNASE2A | DPEP1 | DRAM1 | E2F1 | ECE1 | EFNA5 | ELMO2 | EPB41L3 | ERN1 | ERO1L | FADD | FAS | FASL | FASLG | FGFR2 | FGFR3 | FHIT | FXR1 | G0S2 | GADD45A | GADD45B | GADD45G | GAPDH | GAS2 | GAS6 | GJA1 | GPR65 | GPX1 | GREM1 | GRK5 | GSN | GULP1 | HIPK2 | HIPK3 | HMOX1 | HRAS | HTATIP2 | IER3 | IFIT2 | IFNG | IGFBP3 | IL17A | IL1A | IL1B | IL2RA | IRF1 | ITGB2 | JADE1 | JAK2 | KCNIP3 | KLF11 | LCN2 | LGALS1 | LGALS7 | LY86 | MAGEH1 | MAPK1 | MAPK14 | MAPK3 | MAPT | MCL1 | MCM2 | MEF2C | MELK | MFN2 | MYD88 | NCF1 | NEK6 | NFKB1 | NFKBIA | NGFR | NLRP3 | NME6 | NOTCH2 | NR3C1 | NR4A1 | NRADD | NTN1 | PARM1 | PARP1 | PDCD4 | PEG3 | PHLDA1 | PLAGL1 | PLSCR1 | PMAIP1 | POLB | PPARD | PPID | PPIF | PPM1F | PPP1R15A | PRDX3 | PRDX5 | PRKCB | PRKD1 | PTEN | PURB | RALB | RB1 | RNF152 | RPS3 | RPS6KA1 | RTKN | RTN4 | S100A8 | S100A9 | SEPT4 | SERPINA3G | SERPINB9 | SGK1 | SGMS1 | SHISA5 | SIRT1 | SNCA | SPIN2B | SQSTM1 | SRGN | STK24 | TF | TGFBR1 | TGFBR2 | TLR2 | TMEM14A | TMEM214 | TNF | TNFAIP1 | TNFAIP8 | TNFRSF12A | TNFRSF1A | TNFRSF1B | TNFSF10 | TNFSF12 | TNFSF9 | TP53 | TPX2 | TRAF2 | TRAIP | TRIB3 | TRIM39 | TRP53 | TSPO | UNC5A | WT1 | WWOX | XBP1 | ZDHHC16 | ZFP36L1 | ZMAT3
1
35. Carbon Tetrachloride glutathione peroxidase activity crocin crocin inhibits the reaction [Carbon Tetrachloride results in decreased glutathione peroxidase activity] 1: Rattus norvegicus Kidney
14 genes: GPX1 | GPX2 | GPX7 | GSTA1 | GSTK1 | GSTM2 | GSTM7 | GSTP1 | GSTT1 | GSTT2 | GSTZ1 | MGST1 | MGST3 | PRDX6
1
36. Carbon Tetrachloride membrane lipid catabolic process Melatonin Melatonin inhibits the reaction [Carbon Tetrachloride results in increased membrane lipid catabolic process] 1: Rattus norvegicus Kidney
2 genes: CYP1B1 | SMPDL3B
1
37. Carbon Tetrachloride lipid oxidation Aspirin Aspirin inhibits the reaction [Carbon Tetrachloride results in increased lipid oxidation] 1: Rattus norvegicus Liver 1 gene: PLA2G7 1
38. Carbon Tetrachloride L-aspartate:2-oxoglutarate aminotransferase activity diphenyldiselenide diphenyldiselenide inhibits the reaction [diphenyldiselenide inhibits the reaction [Carbon Tetrachloride results in increased L-aspartate:2-oxoglutarate aminotransferase activity]] 1: Rattus norvegicus Plasma 1 gene: GOT1 1
39. Carbon Tetrachloride superoxide dismutase activity Carbon Tetrachloride results in increased superoxide dismutase activity 1: Rattus norvegicus Liver
5 genes: CCS | NQO1 | SOD1 | SOD2 | SOD3
1
40. Carbon Tetrachloride alkaline phosphatase activity Carbon Tetrachloride results in increased alkaline phosphatase activity 1: Rattus norvegicus Serum 1 gene: ALPL 1
41. Carbon Tetrachloride lipid oxidation Carbon Tetrachloride results in increased lipid oxidation 1: Mus musculus Serum 1 gene: PLA2G7 1
42. Carbon Tetrachloride protein oxidation Carbon Tetrachloride results in increased protein oxidation 1: Homo sapiens Hepatic Stellate Cells | Cell Line
3 genes: APOA1 | APOA2 | GPX1
1
43. Carbon Tetrachloride L-aspartate:2-oxoglutarate aminotransferase activity Carbon Tetrachloride results in increased L-aspartate:2-oxoglutarate aminotransferase activity 1: Rattus norvegicus Liver 1 gene: GOT1 1
44. Carbon Tetrachloride negative regulation of superoxide dismutase activity Carbon Tetrachloride affects negative regulation of superoxide dismutase activity 1: Mus musculus Liver 1 gene: MIR21 1
45. Carbon Tetrachloride positive regulation of protein export from nucleus HMGB1 | Quercetin Quercetin inhibits the reaction [[Carbon Tetrachloride results in increased positive regulation of protein export from nucleus] which affects the localization of HMGB1 protein] 1: Mus musculus Hepatocytes
8 genes: BAG3 | CAMK1 | GAS6 | IL1B | RAN | TP53 | TPR | WIPF1
1
46. Carbon Tetrachloride negative regulation of superoxide dismutase activity Carbon Tetrachloride results in increased negative regulation of superoxide dismutase activity 1: Rattus norvegicus Liver 1 gene: MIR21 1
47. Carbon Tetrachloride positive regulation of hepatic stellate cell activation RDH13 RDH13 protein promotes the reaction [Carbon Tetrachloride results in increased positive regulation of hepatic stellate cell activation] 1: Mus musculus Liver
5 genes: ACTA2 | LEP | PDGFB | PDGFRB | RPS6KA1
1
48. Carbon Tetrachloride 4-hydroxyproline metabolic process Carbon Tetrachloride affects 4-hydroxyproline metabolic process 1: Rattus norvegicus Liver 1 gene: ERO1L 1
49. Carbon Tetrachloride lipid oxidation Plant Extracts | Thiobarbituric Acid Reactive Substances Plant Extracts inhibits the reaction [[Carbon Tetrachloride results in increased lipid oxidation] which results in increased abundance of Thiobarbituric Acid Reactive Substances] 1: Mus musculus Serum 1 gene: PLA2G7 1
50. Carbon Tetrachloride superoxide dismutase activity Carbon Tetrachloride results in decreased superoxide dismutase activity 1: Rattus norvegicus Kidney
5 genes: CCS | NQO1 | SOD1 | SOD2 | SOD3
1
1–50 of 538 results.