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Chemical Dacarbazine

1–50 of 134 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Dacarbazine apoptotic process Dacarbazine results in increased apoptotic process 1: Homo sapiens Epidermis
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
2. Dacarbazine apoptotic process TNFSF10 [TNFSF10 co-treated with Dacarbazine] results in increased apoptotic process 1: Homo sapiens Epidermis | Cell Line, Tumor
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
3. Dacarbazine apoptotic process Dacarbazine results in increased apoptotic process 1: Mus musculus Intestine, Small | Epithelium
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
4. Dacarbazine apoptotic process O(6)-benzylguanine O(6)-benzylguanine inhibits the reaction [Dacarbazine results in increased apoptotic process] 1: Mus musculus Intestine, Small | Epithelium
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
5. Dacarbazine apoptotic process Metyrapone Metyrapone inhibits the reaction [Dacarbazine results in increased apoptotic process] 1: Mus musculus Intestine, Small | Epithelium
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
6. Dacarbazine cellular response to light stimulus Dacarbazine results in increased cellular response to light stimulus 1: Rattus norvegicus Skin   1
7. Dacarbazine cellular response to light stimulus Dacarbazine results in increased cellular response to light stimulus 1: Rattus norvegicus Cornea   1
8. Dacarbazine cell death Dacarbazine results in increased cell death 1: Homo sapiens Skin | Cell Line, Tumor   1
9. Dacarbazine ATP biosynthetic process Dacarbazine results in decreased ATP biosynthetic process 1: Homo sapiens Hep G2 Cells   1
10. Temozolomide cell proliferation Temozolomide results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
11. Temozolomide cell proliferation Pyrimethamine Pyrimethamine promotes the reaction [Temozolomide results in decreased cell proliferation] 1: Homo sapiens Skin | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
12. Temozolomide cell cycle Pyrimethamine [Pyrimethamine co-treated with Temozolomide] results in decreased cell cycle 1: Homo sapiens Skin | Cell Line, Tumor
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
1
13. Temozolomide apoptotic process Pyrimethamine [Pyrimethamine co-treated with Temozolomide] results in increased apoptotic process 1: Homo sapiens Skin | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
14. Temozolomide apoptotic process Leucovorin | Pyrimethamine Leucovorin inhibits the reaction [[Temozolomide co-treated with Pyrimethamine] results in increased apoptotic process] 1: Homo sapiens Skin | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
15. Temozolomide cell death benzyl isothiocyanate benzyl isothiocyanate promotes the reaction [Temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
16. Temozolomide cell death Chlorhexidine Chlorhexidine promotes the reaction [Temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
17. Temozolomide cell death cloxyquin cloxyquin promotes the reaction [Temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
18. Temozolomide cell death 3,4-dimethoxydalbergione 3,4-dimethoxydalbergione promotes the reaction [Temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
19. Temozolomide cell death Pyrimethamine Pyrimethamine promotes the reaction [Temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
20. Temozolomide cell death Triamterene Triamterene promotes the reaction [Temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
21. Temozolomide cell death Temozolomide results in increased cell death 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 2
22. Temozolomide DNA catabolic process Pyrimethamine [Pyrimethamine co-treated with Temozolomide] results in increased DNA catabolic process 1: Homo sapiens Skin | Cell Line, Tumor   1
23. Temozolomide cell proliferation Pyrimethamine [Pyrimethamine co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
24. Temozolomide cell proliferation etoprine [etoprine co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
25. Temozolomide cell proliferation metoprine [metoprine co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
26. Temozolomide cell proliferation Methotrexate [Methotrexate co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
27. Temozolomide cell proliferation Pyrimethamine [Pyrimethamine co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
28. Temozolomide cell proliferation etoprine [etoprine co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
29. Temozolomide cell proliferation metoprine [metoprine co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
30. Temozolomide cell proliferation Methotrexate [Methotrexate co-treated with Temozolomide] results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
31. Temozolomide autophagy Gossypol [Gossypol co-treated with Temozolomide] results in increased autophagy 1: Homo sapiens Astrocytes | Cell Line, Tumor
7 genes: BECN1 | FBXO32 | MAP1LC3B | PIK3C3 | PRKAA2 | TP53 | TRP53
1
32. Temozolomide cell cycle Temozolomide results in decreased cell cycle 1: Homo sapiens Neuroglia | Cell Line, Tumor
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
3
33. Temozolomide cell cycle O(6)-benzylguanine [Temozolomide co-treated with O(6)-benzylguanine] results in decreased cell cycle 1: Homo sapiens Brain | Cell Line, Tumor
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
1
34. Temozolomide apoptotic process Temozolomide results in increased apoptotic process 1: Mus musculus Intestine, Small | Epithelium
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
35. Temozolomide apoptotic process Temozolomide results in increased apoptotic process 1: Homo sapiens Astrocytes | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
36. Temozolomide cell cycle Temozolomide analog results in decreased cell cycle 1: Homo sapiens Jurkat Cells
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
1
37. Temozolomide apoptotic process Temozolomide analog results in increased apoptotic process 1: Homo sapiens Jurkat Cells
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
38. Temozolomide regulation of mitochondrial membrane potential Temozolomide analog results in decreased regulation of mitochondrial membrane potential 1: Homo sapiens Jurkat Cells
4 genes: BAX | BCL2 | BCL2L1 | SOD2
1
39. Temozolomide autophagy Temozolomide results in increased autophagy 1: Homo sapiens Astrocytes | Cell Line, Tumor
7 genes: BECN1 | FBXO32 | MAP1LC3B | PIK3C3 | PRKAA2 | TP53 | TRP53
2
40. Temozolomide autophagy Quercetin Quercetin promotes the reaction [Temozolomide results in increased autophagy] 1: Homo sapiens Astrocytes | Cell Line, Tumor
7 genes: BECN1 | FBXO32 | MAP1LC3B | PIK3C3 | PRKAA2 | TP53 | TRP53
1
41. Temozolomide apoptotic process Quercetin [Quercetin co-treated with Temozolomide] results in increased apoptotic process 1: Homo sapiens Astrocytes | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
42. Temozolomide cell death Quercetin Temozolomide inhibits the reaction [Quercetin results in increased cell death] 1: Homo sapiens Astrocytes | Cell Line, Tumor 1 gene: CDKN1B 1
43. Temozolomide regulation of mitochondrial membrane potential Quercetin [Quercetin co-treated with Temozolomide] results in decreased regulation of mitochondrial membrane potential 1: Homo sapiens Astrocytes | Cell Line, Tumor
4 genes: BAX | BCL2 | BCL2L1 | SOD2
1
44. Temozolomide cell death IL24 | MGMT IL24 protein promotes the reaction [[Temozolomide results in decreased activity of MGMT protein] which results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
45. Temozolomide cell death MGMT [Temozolomide results in decreased activity of MGMT protein] which results in increased cell death 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
46. Temozolomide cell proliferation Temozolomide results in decreased cell proliferation 2: Mus musculus | Rattus norvegicus Pituitary Gland | Cell Line, Tumor
15 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TP53 | VEGFA
1
47. Temozolomide apoptotic process Temozolomide results in increased apoptotic process 2: Mus musculus | Rattus norvegicus Pituitary Gland | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
48. Temozolomide MAPK cascade Temozolomide results in increased MAPK cascade 1: Homo sapiens Neuroglia | Cell Line, Tumor
4 genes: CCL2 | CSF2 | FGF2 | TNF
1
49. Temozolomide cell aging Temozolomide results in increased cell aging 1: Homo sapiens Neuroglia | Cell Line, Tumor
7 genes: BCL2 | BRCA2 | CDK1 | MTOR | TBX3 | TP53 | TRP53
1
50. Temozolomide cell cycle AKT1 AKT1 protein inhibits the reaction [Temozolomide results in decreased cell cycle] 1: Homo sapiens Neuroglia | Cell Line, Tumor
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
1
1–50 of 134 results.