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Chemical Dacarbazine

1–50 of 133 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. Dacarbazine apoptotic process Dacarbazine results in increased apoptotic process 1: Mus musculus Intestine, Small | Epithelium
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
2. Dacarbazine cell death Dacarbazine results in increased cell death 1: Homo sapiens Skin | Cell Line, Tumor   1
3. Dacarbazine apoptotic process Metyrapone Metyrapone inhibits the reaction [Dacarbazine results in increased apoptotic process] 1: Mus musculus Intestine, Small | Epithelium
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
4. Dacarbazine cellular response to light stimulus Dacarbazine results in increased cellular response to light stimulus 1: Rattus norvegicus Skin   1
5. Dacarbazine cellular response to light stimulus Dacarbazine results in increased cellular response to light stimulus 1: Rattus norvegicus Cornea   1
6. Dacarbazine apoptotic process Dacarbazine results in increased apoptotic process 1: Homo sapiens Epidermis
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
7. Dacarbazine apoptotic process TNFSF10 [TNFSF10 co-treated with Dacarbazine] results in increased apoptotic process 1: Homo sapiens Epidermis | Cell Line, Tumor
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
8. Dacarbazine apoptotic process O(6)-benzylguanine O(6)-benzylguanine inhibits the reaction [Dacarbazine results in increased apoptotic process] 1: Mus musculus Intestine, Small | Epithelium
12 genes: BIRC5 | CASP3 | CASP8 | EPO | IFNA2 | IFNG | IRF1 | MAPK1 | MAPK3 | MCL1 | TNF | TNFSF10
1
9. temozolomide cell death MGMT [temozolomide results in decreased activity of MGMT protein] which results in increased cell death 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
10. temozolomide cell death IL24 | MGMT IL24 protein promotes the reaction [[temozolomide results in decreased activity of MGMT protein] which results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
11. temozolomide regulation of mitochondrial membrane potential temozolomide affects regulation of mitochondrial membrane potential 1: Homo sapiens Brain | Astrocytes | Cell Line, Tumor
4 genes: BAX | BCL2 | BCL2L1 | SOD2
1
12. temozolomide mitotic cell cycle arrest resveratrol resveratrol inhibits the reaction [temozolomide results in increased mitotic cell cycle arrest] 1: Homo sapiens Astrocytes | Cell Line, Tumor
5 genes: CDKN1A | CDKN1B | RGCC | TP53 | TRP53
1
13. temozolomide cell death temozolomide results in increased cell death 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: CDKN1B 1
14. temozolomide cell aging AKT1 AKT1 protein inhibits the reaction [temozolomide results in increased cell aging] 1: Homo sapiens Neuroglia | Cell Line, Tumor
7 genes: BCL2 | BRCA2 | CDK1 | MTOR | TBX3 | TP53 | TRP53
1
15. temozolomide autophagy 3-methyladenine 3-methyladenine inhibits the reaction [temozolomide results in increased autophagy] 1: Homo sapiens Astrocytes | Cell Line, Tumor
7 genes: BECN1 | FBXO32 | MAP1LC3B | PIK3C3 | PRKAA2 | TP53 | TRP53
1
16. temozolomide apoptotic process temozolomide results in increased apoptotic process 2: Mus musculus | Rattus norvegicus Pituitary Gland | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
17. temozolomide cell cycle Pyrimethamine [Pyrimethamine co-treated with temozolomide] results in decreased cell cycle 1: Homo sapiens Skin | Cell Line, Tumor
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
1
18. temozolomide mitotic cell cycle arrest temozolomide results in increased mitotic cell cycle arrest 1: Homo sapiens Brain | Cell Line, Tumor
5 genes: CDKN1A | CDKN1B | RGCC | TP53 | TRP53
1
19. temozolomide cell proliferation Dopamine temozolomide promotes the reaction [Dopamine results in decreased cell proliferation] 1: Rattus norvegicus Brain | Neuroglia | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
20. temozolomide cell death honokiol honokiol affects the reaction [temozolomide results in increased cell death] 1: Homo sapiens A549 Cells 1 gene: CDKN1B 1
21. temozolomide apoptotic process Pyrimethamine [Pyrimethamine co-treated with temozolomide] results in increased apoptotic process 1: Homo sapiens Skin | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
22. temozolomide cell proliferation temozolomide results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
23. temozolomide cell death temozolomide results in increased cell death 1: Homo sapiens MCF-7 Cells 1 gene: CDKN1B 1
24. temozolomide apoptotic process Quercetin [Quercetin co-treated with temozolomide] results in increased apoptotic process 1: Homo sapiens Astrocytes | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
25. temozolomide apoptotic process HSPB1 HSPB1 mutant form promotes the reaction [temozolomide results in increased apoptotic process] 1: Homo sapiens Brain | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
26. temozolomide cell proliferation Pyrimethamine [Pyrimethamine co-treated with temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
27. temozolomide cell proliferation temozolomide results in decreased cell proliferation 2: Homo sapiens | Rattus norvegicus Brain | Neuroglia | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
2
28. temozolomide cell proliferation resveratrol resveratrol promotes the reaction [temozolomide results in decreased cell proliferation] 1: Homo sapiens Brain | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
29. temozolomide reactive oxygen species biosynthetic process temozolomide results in increased reactive oxygen species biosynthetic process 1: Homo sapiens Brain | Cell Line, Tumor   1
30. temozolomide cell death Triamterene Triamterene promotes the reaction [temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
31. temozolomide cell death Disulfiram Disulfiram promotes the reaction [temozolomide results in increased cell death] 1: Homo sapiens Brain | Cell Line, Tumor 1 gene: CDKN1B 1
32. temozolomide cell proliferation etoprine [etoprine co-treated with temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
33. temozolomide cell death Quercetin temozolomide inhibits the reaction [Quercetin results in increased cell death] 1: Homo sapiens Astrocytes | Cell Line, Tumor 1 gene: CDKN1B 1
34. temozolomide cell cycle AKT1 AKT1 protein inhibits the reaction [temozolomide results in decreased cell cycle] 1: Homo sapiens Neuroglia | Cell Line, Tumor
24 genes: ATM | BECN1 | BIRC5 | BRCA2 | CCNB1 | CCND1 | CDC25C | CDK1 | CDKN1A | CDKN1B | CDKN1C | CHEK1 | CHEK2 | FANCD2 | H2AFX | MLH1 | MSH2 | PIK3C3 | RB1 | RGCC | TFDP1 | TP53 | TRP53 | WEE1
1
35. temozolomide cell proliferation Methotrexate [Methotrexate co-treated with temozolomide] results in decreased cell proliferation 1: Homo sapiens Skin | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
36. temozolomide apoptotic process pyrazolanthrone pyrazolanthrone inhibits the reaction [temozolomide results in increased apoptotic process] 1: Homo sapiens Brain | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
37. temozolomide cell death honokiol temozolomide affects the reaction [honokiol results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
38. temozolomide cell death 3,4-dimethoxydalbergione 3,4-dimethoxydalbergione promotes the reaction [temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
39. temozolomide apoptotic process HSPB1 HSPB1 mutant form promotes the reaction [temozolomide results in increased apoptotic process] 1: Homo sapiens Brain | Astrocytes | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
40. temozolomide apoptotic process temozolomide results in increased apoptotic process 1: Homo sapiens Neuroglia | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
41. temozolomide positive regulation of cell death resveratrol | ZBTB7A ZBTB7A protein inhibits the reaction [temozolomide promotes the reaction [resveratrol results in increased positive regulation of cell death]] 1: Homo sapiens Neural Stem Cells | Cell Line, Tumor
6 genes: APC | BCL2L11 | CDKN1A | CDKN1B | MTOR | PTGS2
1
42. temozolomide cell proliferation palbociclib [temozolomide co-treated with palbociclib] results in decreased cell proliferation 1: Homo sapiens Brain | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
43. temozolomide negative regulation of G2/M transition of mitotic cell cycle temozolomide results in increased negative regulation of G2/M transition of mitotic cell cycle 1: Homo sapiens Neuroglia | Cell Line, Tumor 1 gene: CHEK1 1
44. temozolomide cell proliferation Thalidomide [temozolomide co-treated with Thalidomide] results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
45. temozolomide apoptotic process temozolomide analog results in increased apoptotic process 1: Homo sapiens Jurkat Cells
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
46. temozolomide apoptotic process N-methylmesoporphyrin IX N-methylmesoporphyrin IX promotes the reaction [temozolomide results in increased apoptotic process] 1: Homo sapiens Neuroglia | Cell Line, Tumor
37 genes: AKT1 | ATM | BAX | BCL2 | BCL2L1 | BCL2L11 | BECN1 | BIRC5 | CADM1 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CDK1 | CHEK1 | CHEK2 | ELMO1 | FASLG | IL24 | NFKBIA | PARP1 | PHLDA1 | PMAIP1 | POLB | PPP1R15A | RB1 | SEMA3A | TCIM | TNF | TNFAIP3 | TNFRSF19 | TNFSF10 | TP53 | TRP53 | XAF1 | XIAP
1
47. temozolomide cell proliferation Pyrimethamine [Pyrimethamine co-treated with temozolomide] results in decreased cell proliferation 1: Homo sapiens Neuroglia | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
48. temozolomide cell proliferation Dopamine Dopamine promotes the reaction [temozolomide results in decreased cell proliferation] 1: Rattus norvegicus Brain | Neuroglia | Cell Line, Tumor
16 genes: AKT1 | BAX | BCL2 | BCL2L1 | BRCA2 | CDC25C | CDK1 | CSGALNACT1 | CXCL1 | EDNRA | FGF2 | PRL | TFDP1 | TNF | TP53 | VEGFA
1
49. temozolomide cell death temozolomide results in increased cell death 1: Homo sapiens B-Lymphocytes | Cell Line 1 gene: CDKN1B 1
50. temozolomide cell death Chlorhexidine Chlorhexidine promotes the reaction [temozolomide results in increased cell death] 1: Homo sapiens Skin | Cell Line, Tumor 1 gene: CDKN1B 1
1–50 of 133 results.