These are exposure studies associated with the chemical and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Ueyama J, et al. (2014).||In this study, we developed and validated a rapid and sensitive method for quantifying urinary neonicotinoid (NEO) concentrations using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS).||acetamiprid | clothianidin | dinotefuran | imidacloprid | nitenpyram | thiacloprid | thiamethoxam||Study subjects||Japan||urine||acetamiprid | clothianidin | dinotefuran | imidacloprid | nitenpyram | thiacloprid | thiamethoxam||Details|
|2.||Marfo JT, et al. (2015).||Urinary N-desmethylacetamiprid can be used as a biomarker for environmental exposure to acetamiprid, and detection of N-desmethylacetamiprid was associated with increased prevalence of neurological symptoms.||acetamiprid | Insecticides||Controls for disease:Neurologic Manifestations | Subjects with disease:Neurologic Manifestations | Study subjects||Japan||urine||clothianidin | N-desmethylacetamiprid | nitenpyram | thiacloprid | thiamethoxam||Details||Neurologic Manifestations|
|3.||Ellis JK, et al. (2012).||This study shows evidence that metabolic profiling in an uncontrolled human population is capable of identifying intermediate biomarkers of response to cadmium at true environmental concentrations, paving the way for exposome research.||Cadmium||Study subjects||United Kingdom||urine||8-oxo-7-hydrodeoxyguanosine | beta-hydroxyisovaleric acid | Citric Acid | Creatine | Creatinine||Details||cellular response to oxidative stress|
|4.||Park D, et al. (2014).||The use of humidifier disinfectant products containing either polyhexamethylene guanidine phosphate or oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride at home has the potential to cause lung injury, especially in susceptible populations such as infants, preschool-age children, and pregnant women.||oligo(2-
||Children | Pregnant females | Study subjects||Korea, Republic of||Details||Death | Lung Diseases | Lung Diseases, Interstitial|
|5.||Park JH, et al. (2016).||This study revealed a statistically significant exposure-response relationship between humidifier disinfectant and lung injury, and the risk of injury increased with the cumulative exposure, duration of exposure, and exposure per day.||polyhexamethyleneguanidine||Controls for disease:Lung Injury | Subjects with disease:Lung Injury||Korea, Republic of||Details||Lung Injury|