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Chemical Heterocyclic Compounds, 1-Ring

1–50 of 32,599 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 10074-G5 mitotic cell cycle arrest 10074-G5 analog results in increased mitotic cell cycle arrest 1: Homo sapiens HL-60 Cells   1
2. 10074-G5 myeloid cell differentiation 10074-G5 results in increased myeloid cell differentiation 1: Homo sapiens HL-60 Cells   1
3. 10074-G5 myeloid cell differentiation 10074-G5 analog results in increased myeloid cell differentiation 1: Homo sapiens HL-60 Cells   1
4. 10074-G5 ATP biosynthetic process 10074-G5 results in decreased ATP biosynthetic process 1: Homo sapiens HL-60 Cells   1
5. 10074-G5 ATP biosynthetic process 10074-G5 analog results in decreased ATP biosynthetic process 1: Homo sapiens HL-60 Cells   1
6. 10074-G5 cellular lipid biosynthetic process 10074-G5 analog results in increased cellular lipid biosynthetic process 1: Homo sapiens Lung | Cell Line, Tumor   1
7. 10074-G5 cellular lipid biosynthetic process 10074-G5 results in increased cellular lipid biosynthetic process 1: Homo sapiens Lung | Cell Line, Tumor   1
8. 10074-G5 ATP biosynthetic process 10074-G5 results in decreased ATP biosynthetic process 1: Homo sapiens Lung | Cell Line, Tumor   1
9. 10074-G5 ATP biosynthetic process 10074-G5 analog results in decreased ATP biosynthetic process 1: Homo sapiens Lung | Cell Line, Tumor   1
10. 10074-G5 cellular lipid biosynthetic process 10074-G5 results in increased cellular lipid biosynthetic process 1: Homo sapiens HL-60 Cells   1
11. 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine cell proliferation cobaltous chloride | HCRT 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine analog inhibits the reaction [HCRT protein inhibits the reaction [cobaltous chloride results in decreased cell proliferation]] 1: Rattus norvegicus Embryonic Structures | Neurons | Cells, Cultured 1 gene: THPO 1
12. 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine positive regulation of megakaryocyte differentiation THPO 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [THPO protein results in increased positive regulation of megakaryocyte differentiation] 1: Homo sapiens Hematopoietic Stem Cells | Cells, Cultured 1 gene: THPO 1
13. 10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine positive regulation of apoptotic process Tetradecanoylphorbol Acetate [10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine co-treated with Tetradecanoylphorbol Acetate] results in increased positive regulation of apoptotic process 1: Homo sapiens Erythroblasts | Cell Line, Tumor   1
14. 10-decarbamoylmitomycin C apoptotic process 10-decarbamoylmitomycin C results in increased apoptotic process 1: Homo sapiens Cell Line, Tumor
4 genes: CASP3 | CASP9 | CHEK1 | TP53
1
15. 10-hydroxywarfarin xenobiotic glucuronidation 10-hydroxywarfarin results in decreased xenobiotic glucuronidation 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
16. 10-hydroxywarfarin xenobiotic glucuronidation Zidovudine [10-hydroxywarfarin results in decreased xenobiotic glucuronidation] which results in decreased glucuronidation of Zidovudine 2: Homo sapiens | Rattus norvegicus Microsomes, Liver   1
17. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea cellular response to food Dietary Fats 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Dietary Fats results in increased cellular response to food] 1: Mus musculus Liver | Endoplasmic Reticulum   1
18. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea cellular response to food Dietary Fats 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea inhibits the reaction [Dietary Fats results in increased cellular response to food] 1: Mus musculus Adipose Tissue | Endoplasmic Reticulum   1
19. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea cell proliferation Diazepam | tetramethylenedisulfotetramine [Diazepam co-treated with 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea] promotes the reaction [tetramethylenedisulfotetramine results in increased cell proliferation] 1: Mus musculus Hippocampus | Astrocytes
2 genes: AKT1 | CYP1A1
1
20. 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea microglial cell activation Diazepam | tetramethylenedisulfotetramine [Diazepam co-treated with 1-(1-methanesulfonylpiperidin-4-yl)-3-(4-trifluoromethoxyphenyl)urea] inhibits the reaction [tetramethylenedisulfotetramine results in increased microglial cell activation] 1: Mus musculus Hippocampus | Microglia   1
21. 1-(1-naphthyl)piperazine negative regulation of colon smooth muscle contraction Serotonin 1-(1-naphthyl)piperazine inhibits the reaction [Serotonin results in increased negative regulation of colon smooth muscle contraction] 1: Cavia porcellus Colon   1
22. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole histamine secretion mediated by immunoglobulin GAST 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [GAST protein results in increased histamine secretion mediated by immunoglobulin] 1: Rattus norvegicus Stomach | Enterochromaffin-like Cells | Cells, Cultured   1
23. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inorganic cation import across plasma membrane AGT 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [AGT protein modified form results in increased inorganic cation import across plasma membrane] 1: Rattus norvegicus Kidney | Podocytes | Cells, Cultured   1
24. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole regulation of cytosolic calcium ion concentration bisphenol A 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [bisphenol A affects regulation of cytosolic calcium ion concentration] 1: Canis lupus familiaris Madin Darby Canine Kidney Cells   1
25. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole calcium ion homeostasis Gallic Acid 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Gallic Acid affects calcium ion homeostasis] 1: Homo sapiens Brain | Cell Line, Tumor 1 gene: CASR 1
26. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole positive regulation of store-operated calcium channel activity Thapsigargin 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Thapsigargin results in increased positive regulation of store-operated calcium channel activity] 1: Rattus norvegicus Basophils | Cell Line, Tumor   1
27. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole manganese ion transmembrane transport ADCYAP1 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [ADCYAP1 protein modified form results in increased manganese ion transmembrane transport] 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
28. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole manganese ion transmembrane transport ADCYAP1 | Manganese 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[ADCYAP1 protein modified form results in increased manganese ion transmembrane transport] which results in increased uptake of Manganese] 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
29. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole manganese ion transmembrane transport Thapsigargin 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Thapsigargin results in increased manganese ion transmembrane transport] 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
30. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole manganese ion transmembrane transport Manganese | Thapsigargin 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[Thapsigargin results in increased manganese ion transmembrane transport] which results in increased uptake of Manganese] 1: Bos taurus Adrenal Medulla | Chromaffin Cells | Cells, Cultured   1
31. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole regulation of cell morphogenesis involved in phenotypic switching Tetradecanoylphorbol Acetate 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased regulation of cell morphogenesis involved in phenotypic switching] 1: Mus musculus Microglia | Cell Line, Transformed   1
32. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole cellular calcium ion homeostasis Cytochalasin B 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Cytochalasin B affects cellular calcium ion homeostasis] 1: Homo sapiens Breast | Cell Line, Tumor 1 gene: CASR 1
33. 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole calcium ion homeostasis Doxorubicin 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [Doxorubicin affects calcium ion homeostasis] 1: Rattus norvegicus Myocytes, Cardiac 1 gene: CASR 1
34. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole cell proliferation gemcitabine [gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in decreased cell proliferation 1: Homo sapiens Pancreas | Cell Line, Tumor   1
35. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy 3-methyladenine | gemcitabine 3-methyladenine inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
36. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy chloroquine diphosphate | gemcitabine chloroquine diphosphate inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
37. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy Acetylcysteine | gemcitabine Acetylcysteine inhibits the reaction [[gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy] 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
38. 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole autophagy gemcitabine [gemcitabine co-treated with 1-(2,3-dichlorobenzoyl)-5-methoxy-2-methyl-(2-(mopholin-4-yl)ethyl)-1H-indole] results in increased autophagy 1: Homo sapiens Pancreas | Cell Line, Tumor 1 gene: XBP1 1
39. 1,2,4-triazole cell proliferation 1,2,4-triazole analog results in decreased cell proliferation 1: Homo sapiens Hep G2 Cells 1 gene: VEGFA 1
40. 1,2,4-triazole angiogenesis Carbon Tetrachloride | Diethylnitrosamine 1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased angiogenesis] 1: Rattus norvegicus Liver
2 genes: EPHB4 | VEGFA
1
41. 1,2,4-triazole L-aspartate:2-oxoglutarate aminotransferase activity Carbon Tetrachloride | Diethylnitrosamine 1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased L-aspartate:2-oxoglutarate aminotransferase activity] 1: Rattus norvegicus Serum   1
42. 1,2,4-triazole lipid catabolic process Carbon Tetrachloride | Diethylnitrosamine 1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased lipid catabolic process] 1: Rattus norvegicus Liver   1
43. 1,2,4-triazole glutathione biosynthetic process Carbon Tetrachloride | Diethylnitrosamine 1,2,4-triazole analog inhibits the reaction [[Diethylnitrosamine co-treated with Carbon Tetrachloride] results in decreased glutathione biosynthetic process] 1: Rattus norvegicus Liver   1
44. 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide positive regulation of behavioral fear response flesinoxan 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide inhibits the reaction [flesinoxan affects positive regulation of behavioral fear response] 1: Rattus norvegicus     1
45. 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide positive regulation of behavioral fear response 8-Hydroxy-2-(di-n-propylamino)tetralin 1,2-benzisothiazol-3(2H)-one, 2-(4-(4-(7-chloro-2,3-dihydro-1,4-benzodioxin-5-yl)-1-piperazinyl)butyl)-, 1,1-dioxide inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin affects positive regulation of behavioral fear response] 1: Rattus norvegicus     1
46. (1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate) aerobic respiration mephedrone (1-(2-(bis(4-fluorophenyl)methoxy)ethyl)-4-(3-hydroxy-3-phenylpropyl) piperazinyl decanoate) inhibits the reaction [mephedrone results in decreased aerobic respiration] 1: Homo sapiens Cell Line, Tumor | Mitochondria   1
47. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of monocyte extravasation AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of monocyte extravasation] 1: Mus musculus Aorta   1
48. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of macrophage chemotaxis AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of macrophage chemotaxis] 1: Mus musculus Aorta   1
49. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of T cell chemotaxis AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of T cell chemotaxis] 1: Mus musculus Aorta   1
50. 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea positive regulation of superoxide anion generation AGT 1-(2-bromophenyl)-3-(7-cyano-3H-benzotriazol-4-yl)urea inhibits the reaction [AGT protein modified form results in increased positive regulation of superoxide anion generation] 1: Mus musculus Aorta
2 genes: AGT | CYBA
1
1–50 of 32,599 results.