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Chemical Mustard Compounds

1–50 of 496 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea DNA repair 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased DNA repair 1: Homo sapiens MCF-7 Cells
9 genes: ATM | CHEK1 | CHEK2 | ERCC3 | ERCC5 | FANCD2 | MGMT | PARP1 | RAD51
1
2. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea mitotic cell cycle arrest 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased mitotic cell cycle arrest 1: Homo sapiens MCF-7 Cells   1
3. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea apoptotic process 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in increased apoptotic process 1: Homo sapiens MCF-7 Cells
8 genes: ATM | CASP7 | CASP8 | CASP9 | CHEK1 | CHEK2 | ERCC3 | PARP1
1
4. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea cell proliferation 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in decreased cell proliferation 1: Homo sapiens MCF-7 Cells   1
5. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea cell proliferation 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in decreased cell proliferation] 1: Homo sapiens MCF-7 Cells   1
6. 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea cell proliferation 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine 4-cyclohexylmethoxy-5-nitrosopyrimidine-2,6-diamine promotes the reaction [1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea results in decreased cell proliferation] 1: Homo sapiens MCF-7 Cells   1
7. 2,2',2''-trichlorotriethylamine DNA alkylation 2,2',2''-trichlorotriethylamine results in increased DNA alkylation     1
8. 2-chloroethyl ethyl sulfide DNA alkylation 2-chloroethyl ethyl sulfide results in increased DNA alkylation     1
9. 2-chloroethyl ethyl sulfide positive regulation of cell death 2-chloroethyl ethyl sulfide results in increased positive regulation of cell death 1: Homo sapiens Keratinocytes | Cell Line
3 genes: IL1B | PTGS2 | TXNRD1
1
10. 2-chloroethyl ethyl sulfide protein poly-ADP-ribosylation 2-chloroethyl ethyl sulfide results in increased protein poly-ADP-ribosylation 1: Homo sapiens Keratinocytes | Cell Line 1 gene: PARP1 2
11. 2-chloroethyl ethyl sulfide positive regulation of NAD+ ADP-ribosyltransferase activity 2-chloroethyl ethyl sulfide results in increased positive regulation of NAD+ ADP-ribosyltransferase activity 1: Homo sapiens Keratinocytes | Cell Line   1
12. 2-chloroethyl ethyl sulfide protein poly-ADP-ribosylation veliparib veliparib inhibits the reaction [2-chloroethyl ethyl sulfide results in increased protein poly-ADP-ribosylation] 1: Homo sapiens Keratinocytes | Cell Line 1 gene: PARP1 1
13. 2-chloroethyl ethyl sulfide positive regulation of NAD+ ADP-ribosyltransferase activity veliparib veliparib inhibits the reaction [2-chloroethyl ethyl sulfide results in increased positive regulation of NAD+ ADP-ribosyltransferase activity] 1: Homo sapiens Keratinocytes | Cell Line   1
14. 2-chloroethyl ethyl sulfide protein poly-ADP-ribosylation Ethanol | Hydrochloric Acid [[Ethanol co-treated with Hydrochloric Acid] results in decreased hydrolysis of 2-chloroethyl ethyl sulfide] which results in increased protein poly-ADP-ribosylation 1: Homo sapiens Keratinocytes | Cell Line 1 gene: PARP1 1
15. 2-chloroethyl ethyl sulfide positive regulation of NAD+ ADP-ribosyltransferase activity Ethanol | Hydrochloric Acid [[Ethanol co-treated with Hydrochloric Acid] results in decreased hydrolysis of 2-chloroethyl ethyl sulfide] which results in increased positive regulation of NAD+ ADP-ribosyltransferase activity 1: Homo sapiens Keratinocytes | Cell Line   1
16. 2-chloroethyl ethyl sulfide protein poly-ADP-ribosylation PARP1 PARP1 protein promotes the reaction [2-chloroethyl ethyl sulfide results in increased protein poly-ADP-ribosylation] 1: Homo sapiens Keratinocytes | Cell Line 1 gene: PARP1 1
17. 2-chloroethyl ethyl sulfide positive regulation of apoptotic process 2-chloroethyl ethyl sulfide results in increased positive regulation of apoptotic process 1: Homo sapiens Keratinocytes | Cell Line
28 genes: ADRB2 | AKT1 | ATM | BAK1 | BAX | BCL2L1 | BIK | CASP2 | CASP3 | CASP6 | CASP8 | CASP9 | FOSL1 | IL1B | IL6 | JUN | MAPK8 | MAPK9 | MMP9 | NOS2 | PTGS2 | RELA | SMPD1 | SMPD2 | SNCA | SOD1 | TNF | TP53
1
18. 2-chloroethyl ethyl sulfide positive regulation of necrotic cell death 2-chloroethyl ethyl sulfide results in increased positive regulation of necrotic cell death 1: Homo sapiens Keratinocytes | Cell Line   1
19. 2-chloroethyl ethyl sulfide DNA alkylation 2-chloroethyl ethyl sulfide results in increased DNA alkylation 1: Homo sapiens Keratinocytes | Cell Line   1
20. 2-chloroethyl ethyl sulfide positive regulation of cell proliferation 2-chloroethyl ethyl sulfide results in decreased positive regulation of cell proliferation 1: Homo sapiens Keratinocytes | Cell Line
14 genes: ADRB2 | AKT1 | BCL2 | BCL2L1 | CCND1 | CDK2 | FOSL1 | IL1B | IL6 | JUN | MAPK1 | PTGS2 | RELA | TNF
1
21. 2-chloroethyl ethyl sulfide positive regulation of NAD metabolic process 2-chloroethyl ethyl sulfide results in increased positive regulation of NAD metabolic process 1: Homo sapiens Keratinocytes | Cell Line   1
22. 2-chloroethyl ethyl sulfide positive regulation of NAD metabolic process NAD [2-chloroethyl ethyl sulfide results in increased positive regulation of NAD metabolic process] which results in decreased abundance of NAD 1: Homo sapiens Keratinocytes | Cell Line   1
23. 2-chloroethyl ethyl sulfide positive regulation of NAD metabolic process veliparib veliparib inhibits the reaction [2-chloroethyl ethyl sulfide results in increased positive regulation of NAD metabolic process] 1: Homo sapiens Keratinocytes | Cell Line   1
24. 2-chloroethyl ethyl sulfide positive regulation of NAD metabolic process NAD | veliparib veliparib inhibits the reaction [[2-chloroethyl ethyl sulfide results in increased positive regulation of NAD metabolic process] which results in decreased abundance of NAD] 1: Homo sapiens Keratinocytes | Cell Line   1
25. 2-chloroethyl ethyl sulfide positive regulation of cell proliferation veliparib veliparib promotes the reaction [2-chloroethyl ethyl sulfide results in decreased positive regulation of cell proliferation] 1: Homo sapiens Keratinocytes | Cell Line
14 genes: ADRB2 | AKT1 | BCL2 | BCL2L1 | CCND1 | CDK2 | FOSL1 | IL1B | IL6 | JUN | MAPK1 | PTGS2 | RELA | TNF
1
26. 2-chloroethyl ethyl sulfide cell death 2-chloroethyl ethyl sulfide results in increased cell death 1: Homo sapiens Skin | Keratinocytes | Cells, Cultured 1 gene: FOSL2 1
27. 2-chloroethyl ethyl sulfide response to toxic substance Cholinesterase Inhibitors | Indomethacin [[Indomethacin binds to Cholinesterase Inhibitors] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
28. 2-chloroethyl ethyl sulfide response to toxic substance Cholinesterase Inhibitors | Diclofenac [[Diclofenac binds to Cholinesterase Inhibitors] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
29. 2-chloroethyl ethyl sulfide response to toxic substance Cholinesterase Inhibitors | Naproxen [[Naproxen binds to Cholinesterase Inhibitors] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
30. 2-chloroethyl ethyl sulfide response to toxic substance Ibuprofen | Pyridostigmine Bromide [[Ibuprofen binds to Pyridostigmine Bromide analog] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
31. 2-chloroethyl ethyl sulfide response to toxic substance Ibuprofen | Neostigmine [[Ibuprofen binds to Neostigmine analog] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
32. 2-chloroethyl ethyl sulfide response to toxic substance Indomethacin | Neostigmine [[Indomethacin binds to Neostigmine analog] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
33. 2-chloroethyl ethyl sulfide response to toxic substance Galantamine | Naproxen [[Naproxen binds to Galantamine] which results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
34. 2-chloroethyl ethyl sulfide response to toxic substance Diclofenac [Diclofenac results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Ear | Skin
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
35. 2-chloroethyl ethyl sulfide positive regulation of superoxide anion generation 2-chloroethyl ethyl sulfide results in increased positive regulation of superoxide anion generation 1: Mus musculus Lung
3 genes: CXCL1 | GSTP1 | SOD1
1
36. 2-chloroethyl ethyl sulfide prostaglandin metabolic process 2-chloroethyl ethyl sulfide results in increased prostaglandin metabolic process 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
37. 2-chloroethyl ethyl sulfide prostaglandin metabolic process Dinoprostone [2-chloroethyl ethyl sulfide results in increased prostaglandin metabolic process] which results in increased secretion of Dinoprostone 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
38. 2-chloroethyl ethyl sulfide prostaglandin metabolic process Epoprostenol [2-chloroethyl ethyl sulfide results in increased prostaglandin metabolic process] which results in decreased secretion of Epoprostenol metabolite 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
39. 2-chloroethyl ethyl sulfide positive regulation of neutrophil extravasation 2-chloroethyl ethyl sulfide results in increased positive regulation of neutrophil extravasation 1: Mus musculus Lung 1 gene: IL1A 1
40. 2-chloroethyl ethyl sulfide positive regulation of superoxide anion generation des-aspartate-angiotensin I des-aspartate-angiotensin I inhibits the reaction [2-chloroethyl ethyl sulfide results in increased positive regulation of superoxide anion generation] 1: Mus musculus Lung
3 genes: CXCL1 | GSTP1 | SOD1
1
41. 2-chloroethyl ethyl sulfide prostaglandin metabolic process des-aspartate-angiotensin I des-aspartate-angiotensin I promotes the reaction [2-chloroethyl ethyl sulfide results in increased prostaglandin metabolic process] 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
42. 2-chloroethyl ethyl sulfide prostaglandin metabolic process des-aspartate-angiotensin I | Dinoprostone des-aspartate-angiotensin I promotes the reaction [[2-chloroethyl ethyl sulfide results in increased prostaglandin metabolic process] which results in increased secretion of Dinoprostone] 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
43. 2-chloroethyl ethyl sulfide prostaglandin metabolic process des-aspartate-angiotensin I [des-aspartate-angiotensin I co-treated with 2-chloroethyl ethyl sulfide] results in increased prostaglandin metabolic process 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
44. 2-chloroethyl ethyl sulfide prostaglandin metabolic process des-aspartate-angiotensin I | Epoprostenol [[des-aspartate-angiotensin I co-treated with 2-chloroethyl ethyl sulfide] results in increased prostaglandin metabolic process] which results in increased secretion of Epoprostenol metabolite 1: Mus musculus Lung
6 genes: PDPN | PTGDS | PTGES | PTGES2 | PTGS2 | TNFRSF1A
1
45. 2-chloroethyl ethyl sulfide positive regulation of neutrophil extravasation des-aspartate-angiotensin I des-aspartate-angiotensin I inhibits the reaction [2-chloroethyl ethyl sulfide results in increased positive regulation of neutrophil extravasation] 1: Mus musculus Lung 1 gene: IL1A 1
46. 2-chloroethyl ethyl sulfide response to toxic substance Losartan [Losartan results in decreased response to toxic substance] which results in decreased susceptibility to 2-chloroethyl ethyl sulfide 1: Mus musculus Lung
13 genes: BAX | BCL2 | CAT | CCNB1 | CDK1 | CDK2 | FOS | FOSL2 | GSTP1 | MAPK1 | MAPK3 | MAPK9 | XPA
1
47. 2-chloroethyl ethyl sulfide leukocyte migration involved in inflammatory response 2-chloroethyl ethyl sulfide results in increased leukocyte migration involved in inflammatory response 1: Mus musculus Ear | Skin 1 gene: CCL2 1
48. 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid cell death 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid results in increased cell death 1: Homo sapiens Cell Line | Umbilical Veins | Endothelial Cells   1
49. 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid cell death 4-((2-chloroethyl)(2-mesyloxyethyl)amino)benzoylglutamic acid results in increased cell death 1: Homo sapiens Cell Line, Tumor | Ovary   1
50. 4-hydroxycyclophosphamide apoptotic process 4-hydroxycyclophosphamide results in increased apoptotic process 1: Rattus norvegicus Ovarian Follicle 1 gene: MAPK14 1
1–50 of 496 results.