| 1. |
Beclomethasone
|
apoptotic process
|
|
Beclomethasone results in increased apoptotic process |
1: Homo sapiens |
Eosinophils |
22 genes: BCL2L13 | CASP9 | CHAC1 | CHEK2 | DDIT4 | DHCR24 | DIABLOA | EGLN3 | IGFBP3 | IL1B | IL2RA | MCM2 | NR3C1 | NR4A1 | PERP | PHLDA2 | RB1 | RBM25 | SGK1 | TNF | TP53INP1 | XIAP
|
1 |
| 2. |
Beclomethasone
|
lymphocyte activation
|
|
Beclomethasone results in decreased lymphocyte activation |
1: Homo sapiens |
Lung |
|
1 |
| 3. |
Beclomethasone
|
vasoconstriction
|
|
Beclomethasone results in increased vasoconstriction |
1: Homo sapiens |
Blood Vessels |
|
1 |
| 4. |
Beclomethasone
|
apoptotic process
|
Mifepristone
|
Mifepristone inhibits the reaction [Beclomethasone results in increased apoptotic process] |
1: Homo sapiens |
Eosinophils |
22 genes: BCL2L13 | CASP9 | CHAC1 | CHEK2 | DDIT4 | DHCR24 | DIABLOA | EGLN3 | IGFBP3 | IL1B | IL2RA | MCM2 | NR3C1 | NR4A1 | PERP | PHLDA2 | RB1 | RBM25 | SGK1 | TNF | TP53INP1 | XIAP
|
1 |
| 5. |
Beclomethasone
|
lymphocyte activation
|
|
Beclomethasone results in decreased lymphocyte activation |
1: Homo sapiens |
T-Lymphocytes |
|
1 |
| 6. |
Betamethasone
|
positive regulation of cellular extravasation
|
Phorbol Esters
|
Betamethasone inhibits the reaction [Phorbol Esters results in increased positive regulation of cellular extravasation] |
1: Mus musculus |
Ear | Skin |
1 gene: CCL2
|
1 |
| 7. |
Betamethasone
|
regulation of heart rate
|
Norepinephrine
|
Norepinephrine affects the reaction [Betamethasone affects regulation of heart rate] |
1: Rattus norvegicus |
Heart | Heart Atria |
|
1 |
| 8. |
Betamethasone
|
regulation of heart rate
|
|
Betamethasone affects regulation of heart rate |
1: Rattus norvegicus |
Heart | Heart Atria |
|
1 |
| 9. |
Betamethasone
|
regulation of blood pressure
|
|
Betamethasone results in increased regulation of blood pressure |
1: Ovis aries |
Cardiovascular System |
3 genes: ACE | AGTR2 | PTGS2
|
1 |
| 10. |
Betamethasone
|
apoptotic process
|
|
Betamethasone results in decreased apoptotic process |
1: Homo sapiens |
Epidermis |
1 gene: NR3C1
|
1 |
| 11. |
Betamethasone
|
positive regulation of cellular extravasation
|
Oxazolone
|
Betamethasone inhibits the reaction [Oxazolone results in increased positive regulation of cellular extravasation] |
1: Mus musculus |
Ear | Skin |
1 gene: CCL2
|
1 |
| 12. |
Betamethasone
|
histamine secretion mediated by immunoglobulin
|
|
Betamethasone results in decreased histamine secretion mediated by immunoglobulin |
1: Homo sapiens |
Basophils | Cells, Cultured |
|
1 |
| 13. |
betamethasone sodium phosphate
|
cell death
|
Benzalkonium Compounds
|
betamethasone sodium phosphate promotes the reaction [Benzalkonium Compounds results in increased cell death] |
2: Bos taurus | Homo sapiens |
Chondrocytes | Cells, Cultured |
|
1 |
| 14. |
Betamethasone Valerate
|
cell death
|
|
Betamethasone Valerate results in increased cell death |
1: Homo sapiens |
Langerhans Cells |
|
1 |
| 15. |
Dexamethasone
|
glucose homeostasis
|
|
Dexamethasone results in increased glucose homeostasis |
1: Mus musculus |
Blood |
73 genes: ADGRF5 | ADIPOQ | ADIPOR2 | ADRA1B | ADRA2A | AKT1 | AKT2 | ALMS1 | ASPSCR1 | BAD | C1QTNF3 | C5 | CD36 | CEBPA | CNR1 | CRTC2 | CRY2 | DBH | FABP5 | FITM2 | FOXO1 | FOXO3 | G6PC | G6PC2 | GCK | GK | GPR39 | HECTD4 | HIF1A | HNF1A | HNF4A | IGFBP5 | IL6 | INS | INSR | IRS1 | KCNB1 | LEP | MAP2K1 | MLXIPL | NCOR2 | NGFR | NMB | NOTCH2 | NR1H4 | PARK7 | PCK1 | PDE3B | PDK4 | PDX1 | PGD | POMC | PPARG | PRKAA2 | PTCH1 | PTPN2 | PYGL | RBP4 | RMI1 | RPH3AL | RPL11 | RPS6 | SERPINE1 | SIDT2 | SLC18A2 | SLC2A4 | SLC37A4 | SOX4 | STAT3 | STXBP5L | TRPV4 | UBA1 | WFS1
|
1 |
| 16. |
Dexamethasone
|
cell death
|
IL6
|
IL6 protein inhibits the reaction [Dexamethasone results in increased cell death] |
1: Homo sapiens |
Blood | Cell Line, Tumor |
23 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | BRINP1 | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | FOSL2 | GSDME | HMOX1 | HTR2A | IL17A | MAP3K10 | PMP22 | PTGER3 | TGFB2 | TRAF6 | VAPA
|
1 |
| 17. |
Dexamethasone
|
calcium-mediated signaling
|
|
Dexamethasone results in decreased calcium-mediated signaling |
1: Mus musculus |
Spleen | T-Lymphocytes | Cells, Cultured |
26 genes: AGTR1 | AGTR1A | ALMS1 | CARHSP1 | CCL3 | CXCL8 | CXCR4 | EDN1 | EDNRB | GRIN1 | GRIN2B | HTR2B | LAT | LRRK2 | MCOLN1 | MCTP1 | NUDT4 | PLCG1 | PPP1R9A | PPP1R9B | PPP3CA | RCAN1 | SELE | SPHK1 | TNF | TNFSF11
|
1 |
| 18. |
Dexamethasone
|
vasoconstriction
|
Cyclosporine
|
Dexamethasone inhibits the reaction [Cyclosporine results in increased vasoconstriction] |
1: Rattus norvegicus |
Kidney |
13 genes: ACE | AGT | AGTR1A | AVP | CAV1 | EDN1 | EDNRA | EDNRB | EDNRBA | HTR1A | HTR2B | SLC6A4 | TRPM4B.2
|
1 |
| 19. |
Dexamethasone
|
apoptotic DNA fragmentation
|
|
Dexamethasone results in increased apoptotic DNA fragmentation |
1: Mus musculus |
Lymph Nodes | T-Lymphocytes | Cells, Cultured |
8 genes: CASP3 | DFFB | ENDOG | H1F0 | HMGB1 | HMGB2 | KPNA1 | REL
|
1 |
| 20. |
Dexamethasone
|
cellular lipid catabolic process
|
1-Methyl-3-isobutylxanthine
| INS
| licarin A
|
[licarin A affects the susceptibility to [INS protein co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone]] which results in increased cellular lipid catabolic process |
1: Mus musculus |
Mesenchymal Stromal Cells | Cell Line, Tumor |
3 genes: ACADL | MT3 | PNPLA2
|
1 |
| 21. |
Dexamethasone
|
apoptotic process
|
|
Dexamethasone results in increased apoptotic process |
1: Mus musculus |
Thymus Gland | Thymocytes | Cells, Cultured |
325 genes: ACIN1 | ACVR1C | ADAM15 | ADRB1 | AHR | AIFM1 | AKT1 | AKT2 | ALDOC | APBB1 | API5 | APP | AREL1 | ARG2 | ASAH2 | ATG5 | AVP | BAD | BADA | BAG4 | BAG6 | BAK1 | BAX | BBC3 | BCAP31 | BCL10 | BCL2 | BCL2A1A | BCL2B | BCL2L1 | BCL2L11 | BCL2L13 | BCL2L2 | BCL7B | BCLAF1 | BIK | BIRC2 | BIRC3 | BIRC5 | BMF | BMF2 | BNIP3 | BOK | BRAT1 | C19ORF12 | C1D | C1QBP | C3ORF38 | CAPN3 | CARD14 | CARD6 | CASP1 | CASP2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP8AP2 | CASP8L2 | CASP9 | CCAR1 | CCKBR | CCL6 | CD14 | CD2 | CD27 | CDCA7 | CDK1 | CFLAR | CHAC1 | CHI3L1 | CIDEA | CIDEC | CITED1 | CRADD | CST3 | CTNNBL1 | CTSC | CTSH | CXCR4 | CYCS | DAD1 | DAP | DAPK1 | DDIT3 | DDIT4 | DFFB | DHCR24 | DIABLO | DIABLOA | DIDO1 | DIO3 | DLC1 | DPEP1 | DPF1 | DRAM2 | DYNLL1 | DYRK2 | EBAG9 | ECE1 | EI24 | EIF5A | ELMO1 | ELMO2 | EP300 | EPHA7 | EPO | ERBB4 | ERN1 | ERN2 | ERO1L | ESPL1 | EVA1A | FAIM | FAM162A | FAM32A | FAP | FAS | FASL | FASLG | FASTK | FGF8 | FGFR2 | FGFR3 | FOXO1 | FOXO3 | G0S2 | GABARAP | GADD45A | GADD45B | GADD45G | GAPDH | GAS2 | GAS6 | GJA1 | GPER1 | GPX1 | GREM1 | GRK5 | GSN | GULP1 | GZMA | HCAR2 | HIF3A | HINT1 | HIP1R | HIPK2 | HMOX1 | HRAS | HTT | IER3 | IFIT2 | IFNG | IGFBP3 | IL17A | IL1A | IL1B | IL2RA | IRF1 | ITGB2 | ITPR1 | JADE1 | JAK2 | JTB | KLF11 | LALBA | LCK | LCN2 | LGALS1 | LGALS12 | LGALS7 | LSP1 | LTBR | MADD | MAGEH1 | MAL | MAP2K6 | MAP3K10 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MCL1 | MCM2 | MEF2C | MFN2 | MIEN1 | MINDY3 | MKNK2 | MT3 | MUL1 | NAE1 | NCF1 | NFKB1 | NFKBIA | NGFR | NISCH | NME3 | NME6 | NOC2L | NOTCH2 | NR3C1 | NR4A1 | NTN1 | OPA1 | PARM1 | PARP1 | PAWR | PCSK9 | PDCD2 | PDCD5 | PDCD6 | PDCD6IP | PDCD7 | PEA15 | PEA15A | PHLDA2 | PHLDA3 | PIM1 | PIM2 | PIM3 | PKN2 | PLAGL1 | PLEKHF1 | PLK3 | POU4F2 | PPARD | PPID | PPP1R13L | PPP1R15A | PPP2CA | PRDX3 | PRDX5 | PRKCA | PRKCB | PRKCDB | PRUNE2 | PSME3 | PTEN | PTK2B | PYCARD | RACK1 | RAD21 | RB1 | RBM25 | RFFL | RFK | RHOB | RNF130 | ROCK1 | RPL11 | RPS3 | RPS6KB1 | RRAGC | RRP1B | RTN3 | S100A8 | S100A9 | SAP30BP | SCML2 | SFRP2 | SGK1 | SGMS1 | SH3KBP1 | SIRT1 | SIX1 | SLTM | SQSTM1 | SRGN | STEAP3 | STK17B | STK26 | STK4 | SULF1 | TAOK1 | TAOK2 | TAX1BP1A | TF | TGFBR1 | TGFBR2 | TIA1 | TICAM1 | TM2D1 | TMBIM4 | TMEM14A | TMEM173 | TNF | TNFAIP3 | TNFAIP8 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TNFRSF9 | TNFSF10 | TNFSF12 | TNFSF9 | TNIP2 | TP53 | TP63 | TPX2 | TRADD | TRAF1 | TRAF4 | TRIB3 | TRIM35 | TRP53 | TRP53INP1 | TRPV2 | UBE2D3 | UNC5B | USP53 | UXT | VDAC1 | WNT1 | WT1 | WWOX | XIAP | YARS | YPEL3 | ZBTB16 | ZFP36L1 | ZMAT3
|
1 |
| 22. |
Dexamethasone
|
lipid biosynthetic process
|
fat cell differentiation
| INS1
| mansonone G
| rosiglitazone
|
mansonone G inhibits the reaction [[[Dexamethasone co-treated with rosiglitazone co-treated with INS1 protein] results in increased fat cell differentiation] which results in increased lipid biosynthetic process] |
1: Mus musculus |
3T3-L1 Cells |
17 genes: ACLY | ACSL1 | ACSL4 | ACSS2 | AGPS | CH25H | CNR1 | FASN | FAXDC2 | FDFT1 | GCG | INS | MSMO1 | PRKAA2 | SCD | SCD1 | SREBF1
|
1 |
| 23. |
Dexamethasone
|
xenobiotic metabolic process
|
benzyloxyresorufin
|
[Dexamethasone results in increased xenobiotic metabolic process] which results in decreased alkylation of benzyloxyresorufin |
1: Mus musculus |
Liver |
57 genes: AADAC | AHR | AIP | AKR1C1 | ALDH3A1 | AOC2 | AOC3 | AOX1 | ARNT | ARNT2 | CES1 | CES2 | CES3 | CMBL | CYP1A2 | CYP1B1 | CYP2B10 | CYP2B3 | CYP2B6 | CYP2C11 | CYP2C19 | CYP2C8 | CYP2C9 | CYP2E1 | CYP3A4 | CYP3A5 | CYP3A7 | DPEP1 | EPHX1 | EPHX2 | FMO1 | FMO3 | GSTA4 | GSTM2 | GSTO2 | GSTP1 | HNF4A | HSP90AB1 | MGST1 | MGST2 | MGST3 | NCEH1 | NQO1 | NR1I2 | POR | PTGS1 | RORA | RORC | S100A9 | SULT1A1 | SULT1A2 | SULT1B1 | SULT1ST1 | SULT1ST3 | UGT1A6 | UGT1A9 | UGT2B15
|
1 |
| 24. |
Dexamethasone
|
leukocyte degranulation
|
|
Dexamethasone results in decreased leukocyte degranulation |
1: Rattus norvegicus |
Mast Cells | Cell Line |
1 gene: HCK
|
1 |
| 25. |
Dexamethasone
|
positive regulation of sequestering of triglyceride
|
1-Methyl-3-isobutylxanthine
| INS
| mono-(2-ethylhexyl)phthalate
|
mono-(2-ethylhexyl)phthalate promotes the reaction [[1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Dexamethasone] results in increased positive regulation of sequestering of triglyceride] |
1: Ursus maritimus |
Adipocytes | Cells, Cultured |
4 genes: CIDEA | FITM2 | LPL | PLIN5
|
1 |
| 26. |
Dexamethasone
|
fat cell differentiation
|
1-Methyl-3-isobutylxanthine
| INS1
|
[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased fat cell differentiation |
1: Mus musculus |
3T3-L1 Cells |
48 genes: ADGRF5 | AKT2 | ALMS1 | AP1S2 | ARID5B | ARL6 | ARXES2 | ATF5 | BBS1 | BBS7 | BSCL2 | C1QTNF3 | CCND1 | CEBPA | CEBPB | CEBPD | EGR2 | EP300 | FAM120B | FOXO1 | GDF10 | GPX1 | GRK5 | GSK3B | HMGA2 | IL11 | INHBB | INSR | KLF4 | LPIN1 | MED1 | METRNL | MTCH2 | NOC3L | NR4A1 | NR4A3 | OSBPL8 | PIAS1 | PID1 | PLCB1 | PPARG | RETN | RUNX1T1 | SOCS1 | SREBF1 | TRIM32 | VIM | WNT5B
|
3 |
| 27. |
Dexamethasone
|
hepatocyte differentiation
|
alkaline phosphatase activity
| Ascorbic Acid
| Butyric Acid
| Carbon Tetrachloride
| Dimethyl Sulfoxide
| EGF
| HGF
| Niacinamide
| Oncostatin M
|
[[EGF protein co-treated with Oncostatin M co-treated with Dexamethasone co-treated with Niacinamide co-treated with Ascorbic Acid] affects the reaction [[HGF protein co-treated with Dimethyl Sulfoxide co-treated with Butyric Acid] results in increased hepatocyte differentiation]] affects the reaction [Carbon Tetrachloride affects alkaline phosphatase activity] |
1: Mus musculus |
Embryonic Stem Cells |
8 genes: ANXA1 | APC | CPS1 | CYP1A1 | HNF1B | HNF4A | PCK1 | WNT1
|
1 |
| 28. |
Dexamethasone
|
cell death
|
Dizocilpine Maleate
|
Dizocilpine Maleate inhibits the reaction [Dexamethasone results in increased cell death] |
1: Rattus norvegicus |
Cerebellum | Neurons | Cells, Cultured |
23 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | BRINP1 | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | FOSL2 | GSDME | HMOX1 | HTR2A | IL17A | MAP3K10 | PMP22 | PTGER3 | TGFB2 | TRAF6 | VAPA
|
1 |
| 29. |
Dexamethasone
|
cell differentiation
|
|
Dexamethasone results in increased cell differentiation |
1: Homo sapiens |
Umbilical Cord | Hematopoietic Stem Cells |
315 genes: AAMP | ABCB5 | ABHD5 | ACVR1C | ADIRF | AGO2 | AGRN | AKT1 | ANGPT1 | ANGPTL4 | ANKRD49 | ANKS4B | ARHGAP22 | ARHGAP24 | ARHGEF2 | ARHGEF28 | ARNT | ASCL1A | ASCL1B | ATOH8 | BAG6 | BCL7B | BEX1 | BHLHE41 | BMP2 | BMP4 | BMP6 | BMP7 | BMP8A | BMPR1A | BNC1 | C9ORF24 | CAPRIN2 | CBFA2T3 | CCDC136 | CDC42 | CDH2 | CDK6 | CDYL | CEBPA | CEBPB | CEND1 | CENPF | CEP131 | CHRDL1 | CITED1 | CITED2 | CLGN | CLIC4 | CLPTM1 | COL13A1 | COL15A1 | CPLX2 | CREB1 | CSF1 | CSRP2 | CSRP3 | CTBP2 | CTGF | CTNNA2 | CTNNB1 | DCLK1 | DHCR7 | DLD | DLK1 | DLL4 | DMKN | DNER | DOCK7 | DUSP6 | EDA | EDARADD | EFNA2A | EFNB1 | EGFL6 | EID2 | ELAVL3 | EOMES | EP300 | EREG | EXT2 | F11R | FAM120B | FAM210B | FGF10 | FGF2 | FGF4 | FGF8 | FGFR3 | FHL1 | FLNB | FLT1 | FNBP1 | FOXO1 | FRZB | FZD5 | GADD45B | GADD45G | GLI1 | GLI2 | GNA12 | GPER1 | GPM6B | GRB2 | GSK3B | HAND2 | HENMT1 | HERC4 | HES6 | HIF1A | HIST1H4B | HLX | HNF4A | HNRNPU | HSPA1L | HSPA2 | HUWE1 | IFT81 | IGSF9 | IHH | INA | INHA | INHBA | INHBB | INSC | IQCG | ITGAV | JAK2 | JMJD6 | KAZALD1 | KDR | KIF2A | KIT | KLF4 | KLHL10 | LAMA5 | LFNG | LGALS3 | LHX6 | LRRC8A | LRRK2 | LZIC | MAL | MAPK7 | MCL1 | MDFI | MDGA1 | MDK | MEA1 | MEF2C | MGP | MICALCL | MLF1 | MMP19 | MOSMO | MOSPD1 | MYF5 | MYF6 | MYOG | NAV1 | NDE1 | NDRG2 | NDRG4 | NEUROG1 | NGFR | NGRN | NKD1 | NOG | NOTCH1 | NOTCH2 | NOTCH2NLA | NPAS4A | NR1D1 | NR2C2 | NR6A1 | NRP1 | NRP1A | NRP2 | NTRK2 | NUDT21 | ODF2 | ONECUT1 | OSR2 | PAFAH1B1A | PARD3 | PDLIM7 | PDX1 | PGF | PKDCC | PMP22 | POU4F2 | PPARD | PPDPFB | PPP1R9B | PRDM16 | PRKX | PRMT7 | PSME4 | PTBP3 | PTK2B | PTMA | PTPRU | RAB29 | RACGAP1 | RAI14 | RARRES2 | RASAL1 | RASGRP1 | RASGRP4 | RBM24A | RBM45 | RFNG | RHOA | RHOB | RIMBP3 | RIMS1 | RIPOR2 | RNF114 | ROBO1 | ROBO3 | ROBO4 | RORC | RPL4 | RPS3A | RPS7 | RUNX2 | SCRIB | SDC2 | SEMA3AA | SEMA3B | SEMA4F | SEMA4G | SEMA7A | SEPT12 | SERPINE2 | SETD2 | SFMBT1 | SFRP1 | SFRP2 | SH2B3 | SIK1 | SIRT1 | SLC22A16 | SLC2A14 | SLC7A5 | SLCO4C1 | SLIT2 | SLIT3 | SMAD5 | SMOC1 | SORT1 | SOX11 | SOX19A | SOX9 | SPAG4 | SPAST | SPATA18 | SPATA2 | SPP1 | SQSTM1 | SRRM4 | SUV39H1 | SUV39H2 | SYNE1 | SYT2 | TBX18 | TCF12 | TCF21 | TCF23 | TDRD9 | TDRKH | TENM3 | TENM4 | TFF1 | TGFBR1 | TGFBR2 | THOC5 | TLE3 | TMTC3 | TNFRSF12A | TNFSF11 | TNFSF12 | TNP1 | TP53 | TP63 | TRAPPC9 | TSNAX | TWIST1 | TWIST2 | TYMP | UBE2V1 | UHRF2 | UNC13A | UNC45B | USP42 | VAMP5 | VEGFA | VEGFC | VEGFD | VIPAS39 | VPS25 | WNT1 | WNT11 | WNT4 | YIPF3 | YTHDF2 | ZBTB1 | ZBTB7A | ZEB1 | ZFP281 | ZHX3 | ZIC1 | ZNF750 | ZPR1 | ZSCAN21
|
1 |
| 30. |
Dexamethasone
|
fat cell differentiation
|
1-Methyl-3-isobutylxanthine
| INS1
| N-phenylmaleimide
|
[N-phenylmaleimide analog co-treated with 1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased fat cell differentiation |
1: Mus musculus |
3T3-L1 Cells |
48 genes: ADGRF5 | AKT2 | ALMS1 | AP1S2 | ARID5B | ARL6 | ARXES2 | ATF5 | BBS1 | BBS7 | BSCL2 | C1QTNF3 | CCND1 | CEBPA | CEBPB | CEBPD | EGR2 | EP300 | FAM120B | FOXO1 | GDF10 | GPX1 | GRK5 | GSK3B | HMGA2 | IL11 | INHBB | INSR | KLF4 | LPIN1 | MED1 | METRNL | MTCH2 | NOC3L | NR4A1 | NR4A3 | OSBPL8 | PIAS1 | PID1 | PLCB1 | PPARG | RETN | RUNX1T1 | SOCS1 | SREBF1 | TRIM32 | VIM | WNT5B
|
1 |
| 31. |
Dexamethasone
|
oxidation-reduction process
|
benzyloxyresorufin
|
[Dexamethasone results in increased oxidation-reduction process] which results in decreased alkylation of benzyloxyresorufin |
2: Mus musculus | Rattus norvegicus |
Liver |
402 genes: ABCC1 | ABCC4 | ACAD11 | ACAD8 | ACAD9 | ACADL | ACADM | ACADVL | ACOX1 | ACOX2 | ADH1 | ADH1C | ADH4 | ADHFE1 | AGPS | AHNAK | AIFM1 | AIFM2 | AKR1A1 | AKR1B1 | AKR1B3 | AKR1B7 | AKR1C1 | AKR1C3 | AKR1CL | ALDH16A1 | ALDH18A1 | ALDH1A1 | ALDH1A3 | ALDH1A7 | ALDH1B1 | ALDH1L1 | ALDH1L2 | ALDH2 | ALDH3A1 | ALDH3A2A | ALDH4A1 | ALDH8A1 | ALDH9A1B | ALOX12B | ALOX5 | ALOX5AP | AOC2 | AOC3 | AOX1 | ASPH | BBOX1 | BCKDHA | BCKDHB | BDH1 | BDH2 | BMP2 | CAT | CBR1 | CDO1 | CH25H | CIAO3 | CMAH | COQ7 | COX1 | COX2 | COX3 | CP | CRYL1 | CRYZL1 | CTBP2 | CYB561 | CYB5A | CYB5R1 | CYB5R2 | CYB5R3 | CYBB | CYP11A1 | CYP17A1 | CYP19A1 | CYP1A1 | CYP1A2 | CYP1B1 | CYP20A1 | CYP24A1 | CYP27A1 | CYP27A7 | CYP27B1 | CYP2A1 | CYP2A2 | CYP2A6 | CYP2B1 | CYP2B10 | CYP2B15 | CYP2B2 | CYP2B3 | CYP2B6 | CYP2B9 | CYP2C11 | CYP2C19 | CYP2C38 | CYP2C8 | CYP2C9 | CYP2D4 | CYP2D9 | CYP2E1 | CYP2F2 | CYP2K6 | CYP2R1 | CYP2S1 | CYP3A11 | CYP3A13 | CYP3A16 | CYP3A18 | CYP3A23/3A1 | CYP3A25 | CYP3A4 | CYP3A44 | CYP3A5 | CYP3A65 | CYP3A7 | CYP3A9 | CYP3C1 | CYP46A1.3 | CYP4A14 | CYP4A3 | CYP4A8 | CYP4B1 | CYP4F6 | CYP4T8 | CYP4Z1 | CYP51 | CYP51A1 | CYP7A1 | CYP7B1 | CYP8B1 | D2HGDH | DAO.2 | DBH | DCXR | DECR1 | DECR2 | DEGS1 | DEGS2 | DHCR24 | DHCR7 | DHFR2 | DHRS3 | DHRS4L2 | DHRS7 | DHRS7C | DHRS7CB | DIO2 | DIO3 | DLD | DMGDH | DOHH | DPYDB | DUS3L | EHHADH | ENOX1 | ENTPD1 | EPX | ERO1L | ETFA | ETFDH | ETHE1 | FADS1 | FADS2 | FADS3 | FADS6 | FAR2 | FASN | FAXDC2 | FBP2 | FDX1 | FDXR | FH | FMO1 | FMO3 | FMO4 | FMO5 | FOXRED2 | FTO | FXN | G6PD | GAPDH | GAPDHS | GCDHA | GFOD1 | GLRX | GLUD1B | GMPR | GMPR2 | GPD1 | GPD1B | GPD1L | GPX1 | GPX1A | GPX3 | GSR | GSTK1 | GSTO1 | GSTO2 | H6PD | HAAO | HADH | HADHA | HADHB | HAO1 | HIBADH | HIBADHB | HIGD1A | HIGD2A | HMGCR | HMGCRA | HMOX1 | HMOX2 | HMOX2B | HPDL | HPGD | HSD11B1 | HSD11B1LA | HSD11B2 | HSD17B1 | HSD17B10 | HSD17B12 | HSD17B12A | HSD17B12B | HSD17B14 | HSD17B2 | HSD17B6 | HSD17B7 | HSDL2 | IDH1 | IDH2 | IDH3A | IDH3G | IFI30 | IMPDH1 | IMPDH2 | JMJD6 | KCNAB1 | KDM1A | KDM5C | KMO | LBR | LDHA | LDHB | LDHD | LOX | LOXL1 | LOXL2 | LOXL3 | LOXL3B | LOXL4 | MAO | MAOA | MAOB | MARC2 | MDH1 | MDH1AA | MDH2 | ME1 | ME3 | MECR | MGST1 | MICAL1 | MICAL3B | MPO | MSMO1 | MSRB1A | MSRB1B | MSRB2 | MTHFD1B | MTHFD1L | MTHFD2 | MTHFR | NCF1 | ND2 | ND4 | ND5 | ND6 | NDUFA12 | NDUFA2 | NDUFA3 | NDUFA4 | NDUFA5 | NDUFA7 | NDUFA8 | NDUFB1 | NDUFB11 | NDUFB2 | NDUFB4 | NDUFB5 | NDUFB6 | NDUFB8 | NDUFB9 | NDUFC2 | NDUFS1 | NDUFS2 | NDUFS3 | NDUFS4 | NDUFS6 | NDUFS7 | NDUFV2 | NNT | NOS1 | NOS2 | NOS3 | NOX4 | NQO1 | NSDHL | OGDH | OGDHA | OGDHB | P3H2 | P3H3 | P4HA2 | P4HTM | PAM | PARK7 | PCBD1 | PCYOX1 | PDHA1 | PDHB | PDIA4 | PGD | PGK1 | PHF2 | PHGDH | PHYHD1 | PIR | PLOD2 | PNPO | POR | PRDX2 | PRDX3 | PRDX4 | PRDX5 | PRDX6 | PRXL2A | PTGIS | PTGR1 | PTGS1 | PTGS2 | PXDN | PYCR1 | RDH12 | RDH13 | RDH14 | RDH5 | RETSAT | RFESD | RIOX1 | RNLS | RRM1 | RRM2 | SCD | SCD1 | SCD2 | SCD3 | SCDB | SCO2 | SDHA | SDHC | SDHD | SELENBP1 | SELENOT1B | SESN1 | SMOX | SOD1 | SOD2 | SOD3 | SORD | SQLE | SQLEA | SQOR | SRD5A2A | SRXN1 | STEAP3 | SUMF1 | SURF1 | TDH | TDO2 | TDO2A | TH | TM7SF2 | TMLHE | TMX1 | TRH | TXN | TXNL1 | TXNRD1 | TYW5 | UQCR10 | UQCRC1 | UQCRC2 | UQCRQ | USP40 | VAT1 | VCAM1 | VKORC1 | WWOX | XDH | YWHAH | YWHAQA
|
1 |
| 32. |
Dexamethasone
|
apoptotic process
|
|
Dexamethasone results in increased apoptotic process |
1: Rattus norvegicus |
Liver | Cell Line, Tumor |
325 genes: ACIN1 | ACVR1C | ADAM15 | ADRB1 | AHR | AIFM1 | AKT1 | AKT2 | ALDOC | APBB1 | API5 | APP | AREL1 | ARG2 | ASAH2 | ATG5 | AVP | BAD | BADA | BAG4 | BAG6 | BAK1 | BAX | BBC3 | BCAP31 | BCL10 | BCL2 | BCL2A1A | BCL2B | BCL2L1 | BCL2L11 | BCL2L13 | BCL2L2 | BCL7B | BCLAF1 | BIK | BIRC2 | BIRC3 | BIRC5 | BMF | BMF2 | BNIP3 | BOK | BRAT1 | C19ORF12 | C1D | C1QBP | C3ORF38 | CAPN3 | CARD14 | CARD6 | CASP1 | CASP2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP8AP2 | CASP8L2 | CASP9 | CCAR1 | CCKBR | CCL6 | CD14 | CD2 | CD27 | CDCA7 | CDK1 | CFLAR | CHAC1 | CHI3L1 | CIDEA | CIDEC | CITED1 | CRADD | CST3 | CTNNBL1 | CTSC | CTSH | CXCR4 | CYCS | DAD1 | DAP | DAPK1 | DDIT3 | DDIT4 | DFFB | DHCR24 | DIABLO | DIABLOA | DIDO1 | DIO3 | DLC1 | DPEP1 | DPF1 | DRAM2 | DYNLL1 | DYRK2 | EBAG9 | ECE1 | EI24 | EIF5A | ELMO1 | ELMO2 | EP300 | EPHA7 | EPO | ERBB4 | ERN1 | ERN2 | ERO1L | ESPL1 | EVA1A | FAIM | FAM162A | FAM32A | FAP | FAS | FASL | FASLG | FASTK | FGF8 | FGFR2 | FGFR3 | FOXO1 | FOXO3 | G0S2 | GABARAP | GADD45A | GADD45B | GADD45G | GAPDH | GAS2 | GAS6 | GJA1 | GPER1 | GPX1 | GREM1 | GRK5 | GSN | GULP1 | GZMA | HCAR2 | HIF3A | HINT1 | HIP1R | HIPK2 | HMOX1 | HRAS | HTT | IER3 | IFIT2 | IFNG | IGFBP3 | IL17A | IL1A | IL1B | IL2RA | IRF1 | ITGB2 | ITPR1 | JADE1 | JAK2 | JTB | KLF11 | LALBA | LCK | LCN2 | LGALS1 | LGALS12 | LGALS7 | LSP1 | LTBR | MADD | MAGEH1 | MAL | MAP2K6 | MAP3K10 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MCL1 | MCM2 | MEF2C | MFN2 | MIEN1 | MINDY3 | MKNK2 | MT3 | MUL1 | NAE1 | NCF1 | NFKB1 | NFKBIA | NGFR | NISCH | NME3 | NME6 | NOC2L | NOTCH2 | NR3C1 | NR4A1 | NTN1 | OPA1 | PARM1 | PARP1 | PAWR | PCSK9 | PDCD2 | PDCD5 | PDCD6 | PDCD6IP | PDCD7 | PEA15 | PEA15A | PHLDA2 | PHLDA3 | PIM1 | PIM2 | PIM3 | PKN2 | PLAGL1 | PLEKHF1 | PLK3 | POU4F2 | PPARD | PPID | PPP1R13L | PPP1R15A | PPP2CA | PRDX3 | PRDX5 | PRKCA | PRKCB | PRKCDB | PRUNE2 | PSME3 | PTEN | PTK2B | PYCARD | RACK1 | RAD21 | RB1 | RBM25 | RFFL | RFK | RHOB | RNF130 | ROCK1 | RPL11 | RPS3 | RPS6KB1 | RRAGC | RRP1B | RTN3 | S100A8 | S100A9 | SAP30BP | SCML2 | SFRP2 | SGK1 | SGMS1 | SH3KBP1 | SIRT1 | SIX1 | SLTM | SQSTM1 | SRGN | STEAP3 | STK17B | STK26 | STK4 | SULF1 | TAOK1 | TAOK2 | TAX1BP1A | TF | TGFBR1 | TGFBR2 | TIA1 | TICAM1 | TM2D1 | TMBIM4 | TMEM14A | TMEM173 | TNF | TNFAIP3 | TNFAIP8 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TNFRSF9 | TNFSF10 | TNFSF12 | TNFSF9 | TNIP2 | TP53 | TP63 | TPX2 | TRADD | TRAF1 | TRAF4 | TRIB3 | TRIM35 | TRP53 | TRP53INP1 | TRPV2 | UBE2D3 | UNC5B | USP53 | UXT | VDAC1 | WNT1 | WT1 | WWOX | XIAP | YARS | YPEL3 | ZBTB16 | ZFP36L1 | ZMAT3
|
1 |
| 33. |
Dexamethasone
|
apoptotic DNA fragmentation
|
|
Dexamethasone results in increased apoptotic DNA fragmentation |
1: Mus musculus |
Lymphoid Tissue | Cell Line, Tumor |
8 genes: CASP3 | DFFB | ENDOG | H1F0 | HMGB1 | HMGB2 | KPNA1 | REL
|
1 |
| 34. |
Dexamethasone
|
positive regulation of granulocyte macrophage colony-stimulating factor production
|
lipoteichoic acid
|
Dexamethasone inhibits the reaction [lipoteichoic acid affects positive regulation of granulocyte macrophage colony-stimulating factor production] |
1: Homo sapiens |
Respiratory System | Myocytes, Smooth Muscle | Cells, Cultured |
4 genes: IL12B | IL18 | IL1B | RASGRP1
|
1 |
| 35. |
Dexamethasone
|
cell death
|
Ibuprofen
|
[Dexamethasone co-treated with Ibuprofen] results in increased cell death |
1: Mus musculus |
Intestine, Small |
23 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | BRINP1 | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | FOSL2 | GSDME | HMOX1 | HTR2A | IL17A | MAP3K10 | PMP22 | PTGER3 | TGFB2 | TRAF6 | VAPA
|
1 |
| 36. |
Dexamethasone
|
apoptotic process
|
|
Dexamethasone results in increased apoptotic process |
1: Rattus norvegicus |
Stomach | Epithelial Cells | Cells, Cultured |
325 genes: ACIN1 | ACVR1C | ADAM15 | ADRB1 | AHR | AIFM1 | AKT1 | AKT2 | ALDOC | APBB1 | API5 | APP | AREL1 | ARG2 | ASAH2 | ATG5 | AVP | BAD | BADA | BAG4 | BAG6 | BAK1 | BAX | BBC3 | BCAP31 | BCL10 | BCL2 | BCL2A1A | BCL2B | BCL2L1 | BCL2L11 | BCL2L13 | BCL2L2 | BCL7B | BCLAF1 | BIK | BIRC2 | BIRC3 | BIRC5 | BMF | BMF2 | BNIP3 | BOK | BRAT1 | C19ORF12 | C1D | C1QBP | C3ORF38 | CAPN3 | CARD14 | CARD6 | CASP1 | CASP2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP8AP2 | CASP8L2 | CASP9 | CCAR1 | CCKBR | CCL6 | CD14 | CD2 | CD27 | CDCA7 | CDK1 | CFLAR | CHAC1 | CHI3L1 | CIDEA | CIDEC | CITED1 | CRADD | CST3 | CTNNBL1 | CTSC | CTSH | CXCR4 | CYCS | DAD1 | DAP | DAPK1 | DDIT3 | DDIT4 | DFFB | DHCR24 | DIABLO | DIABLOA | DIDO1 | DIO3 | DLC1 | DPEP1 | DPF1 | DRAM2 | DYNLL1 | DYRK2 | EBAG9 | ECE1 | EI24 | EIF5A | ELMO1 | ELMO2 | EP300 | EPHA7 | EPO | ERBB4 | ERN1 | ERN2 | ERO1L | ESPL1 | EVA1A | FAIM | FAM162A | FAM32A | FAP | FAS | FASL | FASLG | FASTK | FGF8 | FGFR2 | FGFR3 | FOXO1 | FOXO3 | G0S2 | GABARAP | GADD45A | GADD45B | GADD45G | GAPDH | GAS2 | GAS6 | GJA1 | GPER1 | GPX1 | GREM1 | GRK5 | GSN | GULP1 | GZMA | HCAR2 | HIF3A | HINT1 | HIP1R | HIPK2 | HMOX1 | HRAS | HTT | IER3 | IFIT2 | IFNG | IGFBP3 | IL17A | IL1A | IL1B | IL2RA | IRF1 | ITGB2 | ITPR1 | JADE1 | JAK2 | JTB | KLF11 | LALBA | LCK | LCN2 | LGALS1 | LGALS12 | LGALS7 | LSP1 | LTBR | MADD | MAGEH1 | MAL | MAP2K6 | MAP3K10 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MCL1 | MCM2 | MEF2C | MFN2 | MIEN1 | MINDY3 | MKNK2 | MT3 | MUL1 | NAE1 | NCF1 | NFKB1 | NFKBIA | NGFR | NISCH | NME3 | NME6 | NOC2L | NOTCH2 | NR3C1 | NR4A1 | NTN1 | OPA1 | PARM1 | PARP1 | PAWR | PCSK9 | PDCD2 | PDCD5 | PDCD6 | PDCD6IP | PDCD7 | PEA15 | PEA15A | PHLDA2 | PHLDA3 | PIM1 | PIM2 | PIM3 | PKN2 | PLAGL1 | PLEKHF1 | PLK3 | POU4F2 | PPARD | PPID | PPP1R13L | PPP1R15A | PPP2CA | PRDX3 | PRDX5 | PRKCA | PRKCB | PRKCDB | PRUNE2 | PSME3 | PTEN | PTK2B | PYCARD | RACK1 | RAD21 | RB1 | RBM25 | RFFL | RFK | RHOB | RNF130 | ROCK1 | RPL11 | RPS3 | RPS6KB1 | RRAGC | RRP1B | RTN3 | S100A8 | S100A9 | SAP30BP | SCML2 | SFRP2 | SGK1 | SGMS1 | SH3KBP1 | SIRT1 | SIX1 | SLTM | SQSTM1 | SRGN | STEAP3 | STK17B | STK26 | STK4 | SULF1 | TAOK1 | TAOK2 | TAX1BP1A | TF | TGFBR1 | TGFBR2 | TIA1 | TICAM1 | TM2D1 | TMBIM4 | TMEM14A | TMEM173 | TNF | TNFAIP3 | TNFAIP8 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TNFRSF9 | TNFSF10 | TNFSF12 | TNFSF9 | TNIP2 | TP53 | TP63 | TPX2 | TRADD | TRAF1 | TRAF4 | TRIB3 | TRIM35 | TRP53 | TRP53INP1 | TRPV2 | UBE2D3 | UNC5B | USP53 | UXT | VDAC1 | WNT1 | WT1 | WWOX | XIAP | YARS | YPEL3 | ZBTB16 | ZFP36L1 | ZMAT3
|
1 |
| 37. |
Dexamethasone
|
apoptotic process
|
|
Dexamethasone results in increased apoptotic process |
1: Rattus norvegicus |
Hippocampus |
325 genes: ACIN1 | ACVR1C | ADAM15 | ADRB1 | AHR | AIFM1 | AKT1 | AKT2 | ALDOC | APBB1 | API5 | APP | AREL1 | ARG2 | ASAH2 | ATG5 | AVP | BAD | BADA | BAG4 | BAG6 | BAK1 | BAX | BBC3 | BCAP31 | BCL10 | BCL2 | BCL2A1A | BCL2B | BCL2L1 | BCL2L11 | BCL2L13 | BCL2L2 | BCL7B | BCLAF1 | BIK | BIRC2 | BIRC3 | BIRC5 | BMF | BMF2 | BNIP3 | BOK | BRAT1 | C19ORF12 | C1D | C1QBP | C3ORF38 | CAPN3 | CARD14 | CARD6 | CASP1 | CASP2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP8AP2 | CASP8L2 | CASP9 | CCAR1 | CCKBR | CCL6 | CD14 | CD2 | CD27 | CDCA7 | CDK1 | CFLAR | CHAC1 | CHI3L1 | CIDEA | CIDEC | CITED1 | CRADD | CST3 | CTNNBL1 | CTSC | CTSH | CXCR4 | CYCS | DAD1 | DAP | DAPK1 | DDIT3 | DDIT4 | DFFB | DHCR24 | DIABLO | DIABLOA | DIDO1 | DIO3 | DLC1 | DPEP1 | DPF1 | DRAM2 | DYNLL1 | DYRK2 | EBAG9 | ECE1 | EI24 | EIF5A | ELMO1 | ELMO2 | EP300 | EPHA7 | EPO | ERBB4 | ERN1 | ERN2 | ERO1L | ESPL1 | EVA1A | FAIM | FAM162A | FAM32A | FAP | FAS | FASL | FASLG | FASTK | FGF8 | FGFR2 | FGFR3 | FOXO1 | FOXO3 | G0S2 | GABARAP | GADD45A | GADD45B | GADD45G | GAPDH | GAS2 | GAS6 | GJA1 | GPER1 | GPX1 | GREM1 | GRK5 | GSN | GULP1 | GZMA | HCAR2 | HIF3A | HINT1 | HIP1R | HIPK2 | HMOX1 | HRAS | HTT | IER3 | IFIT2 | IFNG | IGFBP3 | IL17A | IL1A | IL1B | IL2RA | IRF1 | ITGB2 | ITPR1 | JADE1 | JAK2 | JTB | KLF11 | LALBA | LCK | LCN2 | LGALS1 | LGALS12 | LGALS7 | LSP1 | LTBR | MADD | MAGEH1 | MAL | MAP2K6 | MAP3K10 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MCL1 | MCM2 | MEF2C | MFN2 | MIEN1 | MINDY3 | MKNK2 | MT3 | MUL1 | NAE1 | NCF1 | NFKB1 | NFKBIA | NGFR | NISCH | NME3 | NME6 | NOC2L | NOTCH2 | NR3C1 | NR4A1 | NTN1 | OPA1 | PARM1 | PARP1 | PAWR | PCSK9 | PDCD2 | PDCD5 | PDCD6 | PDCD6IP | PDCD7 | PEA15 | PEA15A | PHLDA2 | PHLDA3 | PIM1 | PIM2 | PIM3 | PKN2 | PLAGL1 | PLEKHF1 | PLK3 | POU4F2 | PPARD | PPID | PPP1R13L | PPP1R15A | PPP2CA | PRDX3 | PRDX5 | PRKCA | PRKCB | PRKCDB | PRUNE2 | PSME3 | PTEN | PTK2B | PYCARD | RACK1 | RAD21 | RB1 | RBM25 | RFFL | RFK | RHOB | RNF130 | ROCK1 | RPL11 | RPS3 | RPS6KB1 | RRAGC | RRP1B | RTN3 | S100A8 | S100A9 | SAP30BP | SCML2 | SFRP2 | SGK1 | SGMS1 | SH3KBP1 | SIRT1 | SIX1 | SLTM | SQSTM1 | SRGN | STEAP3 | STK17B | STK26 | STK4 | SULF1 | TAOK1 | TAOK2 | TAX1BP1A | TF | TGFBR1 | TGFBR2 | TIA1 | TICAM1 | TM2D1 | TMBIM4 | TMEM14A | TMEM173 | TNF | TNFAIP3 | TNFAIP8 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TNFRSF9 | TNFSF10 | TNFSF12 | TNFSF9 | TNIP2 | TP53 | TP63 | TPX2 | TRADD | TRAF1 | TRAF4 | TRIB3 | TRIM35 | TRP53 | TRP53INP1 | TRPV2 | UBE2D3 | UNC5B | USP53 | UXT | VDAC1 | WNT1 | WT1 | WWOX | XIAP | YARS | YPEL3 | ZBTB16 | ZFP36L1 | ZMAT3
|
2 |
| 38. |
Dexamethasone
|
positive regulation of lipid storage
|
1-Methyl-3-isobutylxanthine
| INS
| rosiglitazone
|
rosiglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased positive regulation of lipid storage] |
1: Mus musculus |
3T3-L1 Cells |
10 genes: ACACB | AKT1 | APOB | C3 | HILPDA | IKBKE | NFKB1 | NR1H2 | PLIN5 | TMEM135
|
1 |
| 39. |
Dexamethasone
|
bone growth
|
|
Dexamethasone results in decreased bone growth |
1: Rattus norvegicus |
Femur |
1 gene: LEP
|
1 |
| 40. |
Dexamethasone
|
regulation of blood pressure
|
|
Dexamethasone results in increased regulation of blood pressure |
1: Rattus norvegicus |
Blood Vessels |
43 genes: ACE | ACTA2 | ACVRL1 | AGT | AGTR1A | AHR | AOC3 | ATP1A2 | CALCA | COL1A2 | ECE1 | EDN1 | EDNRA | EDNRB | EDNRBA | EPHX2 | GCH1 | HMOX1 | LEP | MYH6 | NISCH | NOS2 | NOS3 | NPPA | NPPB | NPR1 | NPR2 | NPR3 | NPY | NPY1R | POMC | PPARG | PTGS1 | PTGS2 | REN | RENBP | SCNN1A | SGK1 | SOD1 | SOD2 | SULT1A1 | TAC1 | TRPV4
|
1 |
| 41. |
Dexamethasone
|
lipid biosynthetic process
|
1-Methyl-3-isobutylxanthine
| INS1
|
[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased lipid biosynthetic process |
1: Mus musculus |
3T3-L1 Cells |
17 genes: ACLY | ACSL1 | ACSL4 | ACSS2 | AGPS | CH25H | CNR1 | FASN | FAXDC2 | FDFT1 | GCG | INS | MSMO1 | PRKAA2 | SCD | SCD1 | SREBF1
|
1 |
| 42. |
Dexamethasone
|
fat cell differentiation
|
Ascorbic Acid
| beta-glycerophosphoric acid
| Firemaster 550
| INS1
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased fat cell differentiation |
1: Mus musculus |
Bone Marrow Cells | Cells, Cultured |
48 genes: ADGRF5 | AKT2 | ALMS1 | AP1S2 | ARID5B | ARL6 | ARXES2 | ATF5 | BBS1 | BBS7 | BSCL2 | C1QTNF3 | CCND1 | CEBPA | CEBPB | CEBPD | EGR2 | EP300 | FAM120B | FOXO1 | GDF10 | GPX1 | GRK5 | GSK3B | HMGA2 | IL11 | INHBB | INSR | KLF4 | LPIN1 | MED1 | METRNL | MTCH2 | NOC3L | NR4A1 | NR4A3 | OSBPL8 | PIAS1 | PID1 | PLCB1 | PPARG | RETN | RUNX1T1 | SOCS1 | SREBF1 | TRIM32 | VIM | WNT5B
|
1 |
| 43. |
Dexamethasone
|
positive regulation of osteoblast differentiation
|
Ascorbic Acid
| beta-glycerophosphoric acid
|
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased positive regulation of osteoblast differentiation |
1: Homo sapiens |
Adipose Tissue | Mesenchymal Stromal Cells | Cells, Cultured |
45 genes: ATP6AP1 | BMP2 | BMP4 | BMP6 | BMP7 | BMPR1A | CEBPA | CEBPB | CEBPD | CTNNB1 | CYR61 | DLX5 | FAM20C | FBN2 | FGF2 | GDF10 | GJA1 | GNAS | HGF | IFI204 | IFITM1 | IGF1 | IHH | IL6 | IL6R | IL6ST | ILK | JAG1 | LMNA | LTF | MEF2C | MSX2 | NPPC | PDLIM7 | RUNX2 | SCUBE2 | SFRP2 | SMAD1 | SMAD5 | SOX11 | TP63 | VEGFA | WNT10B | WNT4 | ZHX3
|
1 |
| 44. |
Dexamethasone
|
protein oxidation
|
COL2A1
| Freund's Adjuvant
|
Dexamethasone inhibits the reaction [[Freund's Adjuvant co-treated with COL2A1 protein] results in increased protein oxidation] |
1: Bos taurus |
Spleen |
4 genes: APOA1 | APOA2 | GPX1 | SUMF1
|
1 |
| 45. |
Dexamethasone
|
cell proliferation
|
|
Dexamethasone results in decreased cell proliferation |
1: Homo sapiens |
Lung | Fibroblasts | Cells, Cultured |
218 genes: ACE | ACHE | ADRA1B | ADRA1D | AKT1 | APPL1 | AR | AREG | ARHGEF1 | ASAH2 | ASCC3 | AXIN2 | BAD | BAK1 | BAX | BCAT1 | BCL2 | BCL2L1 | BHLHE41 | BMP4 | BOK | BRAT1 | BRCA2 | CBFA2T3 | CCKBR | CD5 | CD74 | CD81 | CDK1 | CDK4 | CDK5RAP3 | CDK7 | CDK9 | CDV3 | CENPF | CFB | CITED1 | CITED2 | CKLF | CKS1B | CLK1 | CNOT11 | COPS2 | CRIP1 | CSF1 | CSF1R | CTNNB1 | CXCL1 | CYP1A1 | CYR61 | DDIT4 | DICER1 | DKC1 | DLG1 | DLX5 | DPH1 | DTYMK | EDNRA | EGFR | ELF5 | ELN | EMP1 | EMP2 | EPO | EPS8 | ERBB2 | ERBB4 | EREG | FBXL7 | FER | FES | FGF2 | FOXC1 | FSCN1 | GAS6 | GCG | GDNF | GH1 | GLI2 | GLUL | GNAI2 | GNG2 | GNL3 | GOLPH3 | GPX1 | GSK3B | H3F3A | HD | HGF | HMGA2 | HRAS | HTR1A | IFNAR2 | IGF1 | IGFBP4 | IL12A | IL12B | IL15RA | IL18 | IL1A | IL2RA | IL5RA | ILK | INSIG1 | IRF2 | IRS2 | ISG20 | KAT2A | KDM1A | KIF2C | KITLG | LAMA5 | LARP1 | LIPA | LIPG | LRP1 | LY6E | MAP2K1 | MAP4K1 | MIF | MKI67 | MORF4L1 | MRPS27 | MT3 | MYB | MYC | MYH10 | NAB2 | NCF1 | NEDD8 | NPY | NR6A1 | NRG1 | NUPR1 | ORC1 | ORC2 | PAK1IP1 | PARK7 | PCNA | PDK1 | PDPN | PDS5B | PDXK | PES1 | PICALM | PIM1 | PIM2 | POLA1 | PPARD | PRDM4 | PRG4 | PRKAR1B | PRKDC | PRL | PTEN | PTMA | RAC1 | RAPGEF3 | RASGRP4 | RETNLB | RHBDF1 | RPL23A | RPS27 | RRN3 | S100B | SCRIB | SERPINF1 | SIX1 | SKI | SLC29A2 | SNAPC4 | SORL1 | SOX11 | SOX2 | SRC | STAT3 | STAT4 | TACC1 | TACC2 | TBX1 | TCF19 | TGFA | TGFB1 | TGFB2 | TGFBI | THOC5 | THOC7 | TNF | TNFSF13B | TNFSF9 | TOP2A | TP53 | TP63 | TPX2 | TUSC2 | TXN | TXNRD1 | UBA1 | UCHL1 | UHRF1 | UHRF2 | USP13 | USP28 | USP8 | USPL1 | VEGFA | VEGFD | VPS25 | VPS36 | VTN | WDR12 | WNT3A | YAP1 | ZEB1 | ZFP36L1 | ZFP36L2 | ZMYND11 | ZPR1
|
1 |
| 46. |
Dexamethasone
|
cell death
|
|
Dexamethasone results in decreased cell death |
1: Rattus norvegicus |
Substantia Nigra | Microglia |
23 genes: ATP6AP1 | AXIN2 | BCL10 | BNIP3 | BRINP1 | CAMP | CDKN1B | CIDEA | CTSD | EIF4G2 | EMP1 | EMP2 | FOSL2 | GSDME | HMOX1 | HTR2A | IL17A | MAP3K10 | PMP22 | PTGER3 | TGFB2 | TRAF6 | VAPA
|
1 |
| 47. |
Dexamethasone
|
protein modification process
|
Flutamide
|
Dexamethasone promotes the reaction [Flutamide results in increased protein modification process] |
1: Rattus norvegicus |
Hepatocytes | Cells, Cultured |
1 gene: PARP1
|
1 |
| 48. |
Dexamethasone
|
hepatocyte differentiation
|
Ascorbic Acid
| Butyric Acid
| Carbon Tetrachloride
| Dimethyl Sulfoxide
| EGF
| GATA4
| HGF
| Niacinamide
| Oncostatin M
|
Carbon Tetrachloride inhibits the reaction [[[EGF protein co-treated with Oncostatin M co-treated with Dexamethasone co-treated with Niacinamide co-treated with Ascorbic Acid] affects the reaction [[HGF protein co-treated with Dimethyl Sulfoxide co-treated with Butyric Acid] results in increased hepatocyte differentiation]] which results in increased expression of GATA4 protein] |
1: Mus musculus |
Embryonic Stem Cells |
8 genes: ANXA1 | APC | CPS1 | CYP1A1 | HNF1B | HNF4A | PCK1 | WNT1
|
1 |
| 49. |
Dexamethasone
|
apoptotic process
|
Mifepristone
|
Mifepristone inhibits the reaction [Dexamethasone results in increased apoptotic process] |
1: Canis lupus familiaris |
Tendons | Cells, Cultured |
325 genes: ACIN1 | ACVR1C | ADAM15 | ADRB1 | AHR | AIFM1 | AKT1 | AKT2 | ALDOC | APBB1 | API5 | APP | AREL1 | ARG2 | ASAH2 | ATG5 | AVP | BAD | BADA | BAG4 | BAG6 | BAK1 | BAX | BBC3 | BCAP31 | BCL10 | BCL2 | BCL2A1A | BCL2B | BCL2L1 | BCL2L11 | BCL2L13 | BCL2L2 | BCL7B | BCLAF1 | BIK | BIRC2 | BIRC3 | BIRC5 | BMF | BMF2 | BNIP3 | BOK | BRAT1 | C19ORF12 | C1D | C1QBP | C3ORF38 | CAPN3 | CARD14 | CARD6 | CASP1 | CASP2 | CASP3 | CASP4 | CASP6 | CASP7 | CASP8 | CASP8AP2 | CASP8L2 | CASP9 | CCAR1 | CCKBR | CCL6 | CD14 | CD2 | CD27 | CDCA7 | CDK1 | CFLAR | CHAC1 | CHI3L1 | CIDEA | CIDEC | CITED1 | CRADD | CST3 | CTNNBL1 | CTSC | CTSH | CXCR4 | CYCS | DAD1 | DAP | DAPK1 | DDIT3 | DDIT4 | DFFB | DHCR24 | DIABLO | DIABLOA | DIDO1 | DIO3 | DLC1 | DPEP1 | DPF1 | DRAM2 | DYNLL1 | DYRK2 | EBAG9 | ECE1 | EI24 | EIF5A | ELMO1 | ELMO2 | EP300 | EPHA7 | EPO | ERBB4 | ERN1 | ERN2 | ERO1L | ESPL1 | EVA1A | FAIM | FAM162A | FAM32A | FAP | FAS | FASL | FASLG | FASTK | FGF8 | FGFR2 | FGFR3 | FOXO1 | FOXO3 | G0S2 | GABARAP | GADD45A | GADD45B | GADD45G | GAPDH | GAS2 | GAS6 | GJA1 | GPER1 | GPX1 | GREM1 | GRK5 | GSN | GULP1 | GZMA | HCAR2 | HIF3A | HINT1 | HIP1R | HIPK2 | HMOX1 | HRAS | HTT | IER3 | IFIT2 | IFNG | IGFBP3 | IL17A | IL1A | IL1B | IL2RA | IRF1 | ITGB2 | ITPR1 | JADE1 | JAK2 | JTB | KLF11 | LALBA | LCK | LCN2 | LGALS1 | LGALS12 | LGALS7 | LSP1 | LTBR | MADD | MAGEH1 | MAL | MAP2K6 | MAP3K10 | MAP3K5 | MAPK1 | MAPK14 | MAPK3 | MCL1 | MCM2 | MEF2C | MFN2 | MIEN1 | MINDY3 | MKNK2 | MT3 | MUL1 | NAE1 | NCF1 | NFKB1 | NFKBIA | NGFR | NISCH | NME3 | NME6 | NOC2L | NOTCH2 | NR3C1 | NR4A1 | NTN1 | OPA1 | PARM1 | PARP1 | PAWR | PCSK9 | PDCD2 | PDCD5 | PDCD6 | PDCD6IP | PDCD7 | PEA15 | PEA15A | PHLDA2 | PHLDA3 | PIM1 | PIM2 | PIM3 | PKN2 | PLAGL1 | PLEKHF1 | PLK3 | POU4F2 | PPARD | PPID | PPP1R13L | PPP1R15A | PPP2CA | PRDX3 | PRDX5 | PRKCA | PRKCB | PRKCDB | PRUNE2 | PSME3 | PTEN | PTK2B | PYCARD | RACK1 | RAD21 | RB1 | RBM25 | RFFL | RFK | RHOB | RNF130 | ROCK1 | RPL11 | RPS3 | RPS6KB1 | RRAGC | RRP1B | RTN3 | S100A8 | S100A9 | SAP30BP | SCML2 | SFRP2 | SGK1 | SGMS1 | SH3KBP1 | SIRT1 | SIX1 | SLTM | SQSTM1 | SRGN | STEAP3 | STK17B | STK26 | STK4 | SULF1 | TAOK1 | TAOK2 | TAX1BP1A | TF | TGFBR1 | TGFBR2 | TIA1 | TICAM1 | TM2D1 | TMBIM4 | TMEM14A | TMEM173 | TNF | TNFAIP3 | TNFAIP8 | TNFRSF10B | TNFRSF11B | TNFRSF12A | TNFRSF19 | TNFRSF1A | TNFRSF9 | TNFSF10 | TNFSF12 | TNFSF9 | TNIP2 | TP53 | TP63 | TPX2 | TRADD | TRAF1 | TRAF4 | TRIB3 | TRIM35 | TRP53 | TRP53INP1 | TRPV2 | UBE2D3 | UNC5B | USP53 | UXT | VDAC1 | WNT1 | WT1 | WWOX | XIAP | YARS | YPEL3 | ZBTB16 | ZFP36L1 | ZMAT3
|
1 |
| 50. |
Dexamethasone
|
negative regulation of interleukin-17 production
|
|
Dexamethasone results in increased negative regulation of interleukin-17 production |
1: Mus musculus |
T-Lymphocytes |
7 genes: IFNG | IL12A | IL12B | TGFB1 | TLR4 | TNFSF4 | TUSC2
|
1 |
Illuminating how chemicals affect human health.
Pregnadienetriols