Skip navigation

Chemical Pregnanes

1–50 of 1,985 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Dichlorodiphenyldichloroethane [Dichlorodiphenyldichloroethane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
2. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 3,4,5,3',4'-pentachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
3. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Pesticides [Pesticides results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
4. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Dieldrin [Dieldrin results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
5. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway alpha-hexachlorocyclohexane [alpha-hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
6. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway delta-hexachlorocyclohexane [delta-hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
7. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Dichlorodiphenyl Dichloroethylene [Dichlorodiphenyl Dichloroethylene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
8. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway phenanthrene [phenanthrene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
9. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Endrin [Endrin results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
10. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 2,3',4,4',5-pentachlorobiphenyl [2,3',4,4',5-pentachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
11. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Toxaphene [Toxaphene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
12. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Lindane [Lindane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
13. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway PCB 180 [PCB 180 results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
14. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway DDT [DDT results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
15. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Aldrin [Aldrin results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
16. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Benzo(a)pyrene [Benzo(a)pyrene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
17. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway beta-hexachlorocyclohexane [beta-hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
18. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway pyrene [pyrene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
19. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway o,p'-DDT [o,p'-DDT results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
20. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Chlordan [Chlordan results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
21. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Heptachlor [Heptachlor results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
22. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 2,2',3,3',4,4',5-heptachlorobiphenyl [2,2',3,3',4,4',5-heptachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
23. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Soil Pollutants [Soil Pollutants results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
24. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased progesterone receptor signaling pathway 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
25. 17,20-dihydroxy-4-pregnen-3-one androgen receptor signaling pathway 17,20-dihydroxy-4-pregnen-3-one results in increased androgen receptor signaling pathway 1: Gnathopogon caerulescens Sertoli Cells   1
26. 20-hydroximino-4,16-pregnadien-3-one androgen biosynthetic process 20-hydroximino-4,16-pregnadien-3-one results in decreased androgen biosynthetic process 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: CYP17A1 1
27. 20-hydroximino-4,16-pregnadien-3-one positive regulation of cell proliferation 20-hydroximino-4,16-pregnadien-3-one results in increased positive regulation of cell proliferation 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: AR 1
28. 20-hydroximino-4,16-pregnadien-3-one androgen biosynthetic process Dihydrotestosterone [20-hydroximino-4,16-pregnadien-3-one results in decreased androgen biosynthetic process] which results in decreased chemical synthesis of Dihydrotestosterone 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: CYP17A1 1
29. 20-hydroximino-4,16-pregnadien-3-one positive regulation of cell proliferation Dihydrotestosterone 20-hydroximino-4,16-pregnadien-3-one inhibits the reaction [Dihydrotestosterone results in increased positive regulation of cell proliferation] 1: Homo sapiens Prostate | Cell Line, Tumor 1 gene: AR 1
30. 20-hydroximino-4,16-pregnadien-3-one positive regulation of testosterone secretion 20-hydroximino-4,16-pregnadien-3-one results in decreased positive regulation of testosterone secretion 1: Homo sapiens Serum   1
31. Aldosterone apoptotic process NOL3 NOL3 protein inhibits the reaction [Aldosterone results in increased apoptotic process] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
14 genes: AQP2 | CASP3 | DAB2 | FASLG | GAS6 | HMOX1 | JAK2 | MAPK1 | MAPK14 | MAPK3 | NR3C1 | PRKCA | PRKD1 | SGK1
1
32. Aldosterone negative regulation of cell proliferation alachlor alachlor inhibits the reaction [Aldosterone results in increased negative regulation of cell proliferation] 1: Homo sapiens Liver | Cell Line, Tumor
10 genes: AGT | CAV1 | HMOX1 | IL6 | JAK2 | PPARG | PRKCA | TGFB1 | TRIM24 | TSG101
1
33. Aldosterone mineralocorticoid receptor signaling pathway Dimethoate Dimethoate inhibits the reaction [Aldosterone results in increased mineralocorticoid receptor signaling pathway] 1: Homo sapiens Muscle, Smooth, Vascular | Cells, Cultured
2 genes: JAK2 | NR3C2
1
34. Aldosterone mineralocorticoid receptor activity Methoxychlor Methoxychlor inhibits the reaction [Aldosterone results in increased mineralocorticoid receptor activity] 1: Homo sapiens Muscle, Smooth, Vascular | Cells, Cultured 1 gene: NR3C2 1
35. Aldosterone regulation of blood pressure Angiotensin-Converting Enzyme Inhibitors | Nifedipine [Nifedipine promotes the reaction [Angiotensin-Converting Enzyme Inhibitors results in decreased regulation of blood pressure]] which results in decreased abundance of Aldosterone 1: Homo sapiens Cardiovascular System
18 genes: ACE | ACTA2 | AGT | AGTR1A | AGTR2 | ATP1A1 | CYP11B2 | EDN1 | EDNRA | HMOX1 | NPPA | NPPB | POMC | PPARG | REN | SCNN1A | SGK1 | SOD1
1
36. Aldosterone mineralocorticoid receptor activity alachlor alachlor inhibits the reaction [Aldosterone results in increased mineralocorticoid receptor activity] 1: Homo sapiens Muscle, Smooth, Vascular | Cells, Cultured 1 gene: NR3C2 1
37. Aldosterone negative regulation of cell proliferation Atrazine Atrazine metabolite inhibits the reaction [Aldosterone results in increased negative regulation of cell proliferation] 1: Homo sapiens Liver | Cell Line, Tumor
10 genes: AGT | CAV1 | HMOX1 | IL6 | JAK2 | PPARG | PRKCA | TGFB1 | TRIM24 | TSG101
1
38. Aldosterone mineralocorticoid receptor signaling pathway Dichlorodiphenyl Dichloroethylene Dichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased mineralocorticoid receptor signaling pathway] 1: Homo sapiens Muscle, Smooth, Vascular | Cells, Cultured
2 genes: JAK2 | NR3C2
1
39. Aldosterone reactive oxygen species metabolic process Aldosterone results in increased reactive oxygen species metabolic process 1: Rattus norvegicus Liver
2 genes: CTGF | SOD1
1
40. Aldosterone negative regulation of cell proliferation fipronil fipronil inhibits the reaction [Aldosterone results in increased negative regulation of cell proliferation] 1: Homo sapiens Liver | Cell Line, Tumor
10 genes: AGT | CAV1 | HMOX1 | IL6 | JAK2 | PPARG | PRKCA | TGFB1 | TRIM24 | TSG101
1
41. Aldosterone vasoconstriction Phenylephrine Aldosterone promotes the reaction [Phenylephrine results in increased vasoconstriction] 1: Homo sapiens Blood Vessels
6 genes: ACE | AGT | AGTR1A | CAV1 | EDN1 | EDNRA
1
42. Aldosterone DNA damage response, detection of DNA damage tempol tempol inhibits the reaction [Aldosterone results in increased DNA damage response, detection of DNA damage] 1: Rattus norvegicus Liver   1
43. Aldosterone mineralocorticoid receptor activity DDT DDT inhibits the reaction [Aldosterone results in increased mineralocorticoid receptor activity] 1: Homo sapiens Muscle, Smooth, Vascular | Cells, Cultured 1 gene: NR3C2 1
44. Aldosterone reactive oxygen species biosynthetic process Aldosterone results in increased reactive oxygen species biosynthetic process 1: Sus scrofa Kidney Tubules, Proximal | Cell Line   1
45. Aldosterone negative regulation of cell proliferation Methoxychlor Methoxychlor inhibits the reaction [Aldosterone results in increased negative regulation of cell proliferation] 1: Homo sapiens Liver | Cell Line, Tumor
10 genes: AGT | CAV1 | HMOX1 | IL6 | JAK2 | PPARG | PRKCA | TGFB1 | TRIM24 | TSG101
1
46. Aldosterone glutathione biosynthetic process Aldosterone results in increased glutathione biosynthetic process 1: Sus scrofa Kidney Tubules, Proximal | Cell Line 1 gene: GCLC 1
47. Aldosterone negative regulation of cell proliferation Dichlorodiphenyl Dichloroethylene Dichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased negative regulation of cell proliferation] 1: Homo sapiens Liver | Cell Line, Tumor
10 genes: AGT | CAV1 | HMOX1 | IL6 | JAK2 | PPARG | PRKCA | TGFB1 | TRIM24 | TSG101
1
48. Aldosterone apoptotic process CASP8 | NOL3 NOL3 protein affects the reaction [CASP8 protein affects the reaction [Aldosterone results in increased apoptotic process]] 1: Rattus norvegicus Myocytes, Cardiac | Cells, Cultured
14 genes: AQP2 | CASP3 | DAB2 | FASLG | GAS6 | HMOX1 | JAK2 | MAPK1 | MAPK14 | MAPK3 | NR3C1 | PRKCA | PRKD1 | SGK1
1
49. Aldosterone apoptotic process Spironolactone Spironolactone inhibits the reaction [Aldosterone results in increased apoptotic process] 1: Rattus norvegicus Podocytes | Cells, Cultured
14 genes: AQP2 | CASP3 | DAB2 | FASLG | GAS6 | HMOX1 | JAK2 | MAPK1 | MAPK14 | MAPK3 | NR3C1 | PRKCA | PRKD1 | SGK1
1
50. Aldosterone negative regulation of cell proliferation acephate acephate inhibits the reaction [Aldosterone results in increased negative regulation of cell proliferation] 1: Homo sapiens Liver | Cell Line, Tumor
10 genes: AGT | CAV1 | HMOX1 | IL6 | JAK2 | PPARG | PRKCA | TGFB1 | TRIM24 | TSG101
1
1–50 of 1,985 results.