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Chemical Pregnanes

1–50 of 2,201 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Pesticides [Pesticides results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
2. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Soil Pollutants [Soil Pollutants results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
3. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione results in increased progesterone receptor signaling pathway 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
4. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway alpha-hexachlorocyclohexane [alpha-hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
5. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway beta-hexachlorocyclohexane [beta-hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
6. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Hexachlorocyclohexane [Hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
7. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway delta-hexachlorocyclohexane [delta-hexachlorocyclohexane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
8. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Aldrin [Aldrin results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
9. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Dieldrin [Dieldrin results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
10. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Endrin [Endrin results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
11. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway o,p'-DDT [o,p'-DDT results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
12. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway DDT [DDT results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
13. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Dichlorodiphenyl Dichloroethylene [Dichlorodiphenyl Dichloroethylene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
14. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Dichlorodiphenyldichloroethane [Dichlorodiphenyldichloroethane results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
15. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Chlordan [Chlordan results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
16. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Heptachlor [Heptachlor results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
17. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Toxaphene [Toxaphene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
18. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway phenanthrene [phenanthrene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
19. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway pyrene [pyrene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
20. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway Benzo(a)pyrene [Benzo(a)pyrene results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
21. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 2,2',3,3',4,4',5-heptachlorobiphenyl [2,2',3,3',4,4',5-heptachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
22. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway PCB 180 [PCB 180 results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
23. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 3,4,5,3',4'-pentachlorobiphenyl [3,4,5,3',4'-pentachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
24. 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione progesterone receptor signaling pathway 2,3',4,4',5-pentachlorobiphenyl [2,3',4,4',5-pentachlorobiphenyl results in decreased progesterone receptor signaling pathway] which results in decreased susceptibility to 16 alpha-ethyl-21-hydroxy-19-nor-4-pregnene-3,20-dione 1: Homo sapiens Osteoblasts | Cell Line, Tumor 1 gene: PGR 1
25. 17,20-dihydroxy-4-pregnen-3-one androgen receptor signaling pathway 17,20-dihydroxy-4-pregnen-3-one results in increased androgen receptor signaling pathway 1: Gnathopogon caerulescens Sertoli Cells   1
26. 17-alpha-Hydroxypregnenolone C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
27. 17-alpha-Hydroxypregnenolone C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line   1
28. 17-alpha-Hydroxypregnenolone C21-steroid hormone metabolic process Fluconazole [Fluconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
29. 17-alpha-Hydroxypregnenolone C21-steroid hormone metabolic process Fluconazole [Fluconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line   1
30. 17-alpha-Hydroxypregnenolone steroid biosynthetic process Colforsin [Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor 1 gene: CYP17A1 1
31. 17-alpha-Hydroxypregnenolone negative regulation of steroid hormone biosynthetic process Tramadol [Tramadol results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
32. 17-alpha-Hydroxypregnenolone steroid biosynthetic process Promethazine [Promethazine affects steroid biosynthetic process] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor 1 gene: CYP17A1 1
33. 17-alpha-Hydroxypregnenolone steroid biosynthetic process Cetirizine [Cetirizine affects steroid biosynthetic process] which results in increased chemical synthesis of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor 1 gene: CYP17A1 1
34. 17-alpha-Hydroxypregnenolone steroid biosynthetic process fexofenadine [fexofenadine affects steroid biosynthetic process] which affects the chemical synthesis of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor 1 gene: CYP17A1 1
35. 17-alpha-Hydroxypregnenolone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor 1 gene: CYP17A1 1
36. 17-alpha-Hydroxypregnenolone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Rattus norvegicus Testis 1 gene: CYP17A1 1
37. 17-alpha-Hydroxypregnenolone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxypregnenolone 1: Rattus norvegicus Adrenal Glands 1 gene: CYP17A1 1
38. 17-alpha-Hydroxyprogesterone C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line   1
39. 17-alpha-Hydroxyprogesterone C21-steroid hormone metabolic process Ketoconazole [Ketoconazole affects C21-steroid hormone metabolic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
40. 17-alpha-Hydroxyprogesterone C21-steroid hormone metabolic process Fluconazole [Fluconazole affects C21-steroid hormone metabolic process] which affects the abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
41. 17-alpha-Hydroxyprogesterone C21-steroid hormone metabolic process Fluconazole [Fluconazole affects C21-steroid hormone metabolic process] which results in increased abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line   1
42. 17-alpha-Hydroxyprogesterone steroid biosynthetic process Colforsin [Colforsin results in increased steroid biosynthetic process] which results in increased secretion of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
3 genes: CYP11A1 | CYP17A1 | CYP21A2
1
43. 17-alpha-Hydroxyprogesterone negative regulation of steroid hormone biosynthetic process Venlafaxine Hydrochloride [Venlafaxine Hydrochloride results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
44. 17-alpha-Hydroxyprogesterone negative regulation of steroid hormone biosynthetic process Tramadol [Tramadol results in increased negative regulation of steroid hormone biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor   1
45. 17-alpha-Hydroxyprogesterone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Homo sapiens Adrenal Cortex | Cell Line, Tumor
3 genes: CYP11A1 | CYP17A1 | CYP21A2
1
46. 17-alpha-Hydroxyprogesterone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Rattus norvegicus Testis
3 genes: CYP11A1 | CYP17A1 | CYP21A2
1
47. 17-alpha-Hydroxyprogesterone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Rattus norvegicus Adrenal Glands
3 genes: CYP11A1 | CYP17A1 | CYP21A2
1
48. 17-alpha-Hydroxyprogesterone steroid biosynthetic process Atorvastatin [Atorvastatin results in decreased steroid biosynthetic process] which results in decreased abundance of 17-alpha-Hydroxyprogesterone 1: Rattus norvegicus Plasma
3 genes: CYP11A1 | CYP17A1 | CYP21A2
1
49. 17-alpha-Hydroxyprogesterone positive regulation of lipid storage 1-Methyl-3-isobutylxanthine | Dexamethasone | INS | Rosiglitazone 17-alpha-Hydroxyprogesterone inhibits the reaction [[Dexamethasone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased positive regulation of lipid storage] 1: Homo sapiens Subcutaneous Fat | Stem Cells | Cells, Cultured   1
50. 17-alpha-Hydroxyprogesterone positive regulation of lipid storage 1-Methyl-3-isobutylxanthine | INS | Rosiglitazone [17-alpha-Hydroxyprogesterone co-treated with Rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased positive regulation of lipid storage 1: Homo sapiens Subcutaneous Fat | Stem Cells | Cells, Cultured   1
1–50 of 2,201 results.