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Chemical Tretinoin

1–50 of 711 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 4-hydroxyretinoic acid retinoid metabolic process tasquinimod [tasquinimod analog affects retinoid metabolic process] which results in decreased abundance of 4-hydroxyretinoic acid 1: Rattus norvegicus Liver   1
2. 4-hydroxyretinoic acid drug metabolic process 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid [4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid results in increased drug metabolic process] which results in increased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Lung | Cell Line, Tumor
4 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4
1
3. 4-hydroxyretinoic acid drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Microsomes, Liver
4 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4
1
4. 4-hydroxyretinoic acid drug metabolic process Paclitaxel [Paclitaxel results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Microsomes, Liver
4 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4
1
5. 4-hydroxyretinoic acid drug metabolic process Sulfaphenazole [Sulfaphenazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Microsomes, Liver
4 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4
1
6. 4-hydroxyretinoic acid retinoid metabolic process laquinimod [laquinimod analog affects retinoid metabolic process] which results in decreased abundance of 4-hydroxyretinoic acid 1: Rattus norvegicus Liver   1
7. 4-hydroxyretinoic acid pericardium morphogenesis triphenyl phosphate 4-hydroxyretinoic acid inhibits the reaction [triphenyl phosphate results in increased pericardium morphogenesis] 1: Danio rerio Embryo, Nonmammalian | Pericardium   1
8. 4-hydroxyretinoic acid drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Microsomes, Liver
4 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4
1
9. 4-hydroxyretinoic acid drug metabolic process furafylline [furafylline results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-hydroxyretinoic acid 1: Homo sapiens Microsomes, Liver
4 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4
1
10. 4-oxoretinoic acid drug metabolic process Sulfaphenazole [Sulfaphenazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Microsomes, Liver
5 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4 | SULT2A1
1
11. 4-oxoretinoic acid drug metabolic process Troleandomycin [Troleandomycin results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Microsomes, Liver
5 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4 | SULT2A1
1
12. 4-oxoretinoic acid drug metabolic process Paclitaxel [Paclitaxel results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Microsomes, Liver
5 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4 | SULT2A1
1
13. 4-oxoretinoic acid drug metabolic process 4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid [4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid results in increased drug metabolic process] which results in increased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Lung | Cell Line, Tumor
5 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4 | SULT2A1
1
14. 4-oxoretinoic acid drug metabolic process furafylline [furafylline results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Microsomes, Liver
5 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4 | SULT2A1
1
15. 4-oxoretinoic acid drug metabolic process Ketoconazole [Ketoconazole results in decreased drug metabolic process] which results in decreased chemical synthesis of 4-oxoretinoic acid 1: Homo sapiens Microsomes, Liver
5 genes: CYP1A1 | CYP2C8 | CYP2C9 | CYP3A4 | SULT2A1
1
16. 9-cis-4-oxo-13,14-dihydro-retinoic acid retinoid metabolic process laquinimod [laquinimod analog affects retinoid metabolic process] which results in decreased abundance of 9-cis-4-oxo-13,14-dihydro-retinoic acid 1: Rattus norvegicus Serum   1
17. 9-cis-4-oxo-13,14-dihydro-retinoic acid retinoid metabolic process tasquinimod [tasquinimod analog affects retinoid metabolic process] which results in decreased abundance of 9-cis-4-oxo-13,14-dihydro-retinoic acid 1: Rattus norvegicus Liver   1
18. 9-cis-4-oxo-13,14-dihydro-retinoic acid retinoid metabolic process tasquinimod [tasquinimod analog affects retinoid metabolic process] which results in decreased abundance of 9-cis-4-oxo-13,14-dihydro-retinoic acid 1: Rattus norvegicus Serum   1
19. 9-cis-4-oxo-13,14-dihydro-retinoic acid retinoid metabolic process laquinimod [laquinimod analog affects retinoid metabolic process] which results in decreased abundance of 9-cis-4-oxo-13,14-dihydro-retinoic acid 1: Rattus norvegicus Liver   1
20. alitretinoin cell proliferation Tetradecanoylphorbol Acetate alitretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased cell proliferation] 1: Homo sapiens T-Lymphocytes | Cells, Cultured
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
21. alitretinoin positive regulation of cell proliferation alitretinoin results in decreased positive regulation of cell proliferation 1: Mus musculus Keratinocytes | Cell Line, Transformed
47 genes: AKT1 | BCL2 | CAPN1 | CCND3 | CD38 | CD86 | CDKN1B | CIAO1 | EGFR | FGF1 | FN1 | GHRH | HBEGF | HGF | IFNG | IGF1 | IL1B | IL2 | IL24 | IL4 | IL5 | IL6 | INS | INSR | JUN | LEP | MAPK1 | NKX3-1 | NPM1 | ODC1 | PDGFB | PDX1 | PRAME | PTEN | PTGS2 | PTHLH | RARA | RARB | RARG | STAT1 | STS | TGFB1 | THBS1 | TNF | VEGFA | VEGFC | VIPR1
1
22. alitretinoin cell proliferation Calcitriol | Tretinoin [alitretinoin co-treated with Tretinoin co-treated with Calcitriol] results in increased cell proliferation 1: Homo sapiens Keratinocytes | Cells, Cultured
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
23. alitretinoin L-cystine transport Cystine [[alitretinoin results in decreased L-cystine transport] which results in decreased import of Cystine] which results in increased abundance of Cystine 1: Homo sapiens Induced Pluripotent Stem Cells | Extracellular Fluid   1
24. alitretinoin apoptotic process Cisplatin alitretinoin promotes the reaction [Cisplatin results in increased apoptotic process] 1: Homo sapiens Pancreas | Cell Line, Tumor
38 genes: AKT1 | APP | BAX | BCL2 | BCL2A1A | BCL2L11 | CAPN3 | CASP3 | CASP7 | CASP8 | CGB3 | DIO3 | FAS | FASTK | GAPDH | IFNG | IGFBP3 | IL1B | IL24 | IRF1 | ITGB2 | LCN2 | MAPK1 | MAPK3 | PARP1 | PRAME | PTEN | RB1 | RHOB | RPS6KA1 | RPS6KB1 | S100A8 | S100A9 | SERPINB9 | TNF | TNFRSF10A | TNFRSF10B | TNFSF10
1
25. alitretinoin positive regulation of cell proliferation RARG RARG gene mutant form inhibits the reaction [alitretinoin results in decreased positive regulation of cell proliferation] 1: Mus musculus Keratinocytes | Cell Line, Transformed
47 genes: AKT1 | BCL2 | CAPN1 | CCND3 | CD38 | CD86 | CDKN1B | CIAO1 | EGFR | FGF1 | FN1 | GHRH | HBEGF | HGF | IFNG | IGF1 | IL1B | IL2 | IL24 | IL4 | IL5 | IL6 | INS | INSR | JUN | LEP | MAPK1 | NKX3-1 | NPM1 | ODC1 | PDGFB | PDX1 | PRAME | PTEN | PTGS2 | PTHLH | RARA | RARB | RARG | STAT1 | STS | TGFB1 | THBS1 | TNF | VEGFA | VEGFC | VIPR1
1
26. alitretinoin T-helper 2 cell lineage commitment alitretinoin results in increased T-helper 2 cell lineage commitment 1: Mus musculus CD4-Positive T-Lymphocytes | Cells, Cultured   1
27. alitretinoin L-cystine transport Cystine | Ro 41-5253 Ro 41-5253 inhibits the reaction [[[alitretinoin results in decreased L-cystine transport] which results in decreased import of Cystine] which results in increased abundance of Cystine] 1: Homo sapiens Induced Pluripotent Stem Cells | Extracellular Fluid   1
28. alitretinoin lung epithelial cell differentiation alitretinoin affects lung epithelial cell differentiation 1: Homo sapiens Bronchi | Epithelial Cells | Cells, Cultured 1 gene: FOXA1 1
29. alitretinoin apoptotic process gemcitabine alitretinoin promotes the reaction [gemcitabine results in increased apoptotic process] 1: Homo sapiens Pancreas | Cell Line, Tumor
38 genes: AKT1 | APP | BAX | BCL2 | BCL2A1A | BCL2L11 | CAPN3 | CASP3 | CASP7 | CASP8 | CGB3 | DIO3 | FAS | FASTK | GAPDH | IFNG | IGFBP3 | IL1B | IL24 | IRF1 | ITGB2 | LCN2 | MAPK1 | MAPK3 | PARP1 | PRAME | PTEN | RB1 | RHOB | RPS6KA1 | RPS6KB1 | S100A8 | S100A9 | SERPINB9 | TNF | TNFRSF10A | TNFRSF10B | TNFSF10
1
30. alitretinoin cell proliferation alitretinoin results in decreased cell proliferation 1: Homo sapiens Muscles | Cell Line, Tumor
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
31. alitretinoin L-cystine transport Cystine [alitretinoin results in decreased L-cystine transport] which results in decreased import of Cystine 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
32. alitretinoin L-cystine transport Cystine | Ro 41-5253 Ro 41-5253 inhibits the reaction [[alitretinoin results in decreased L-cystine transport] which results in decreased import of Cystine] 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
33. alitretinoin cell proliferation alitretinoin results in decreased cell proliferation 1: Mus musculus Prostate
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
34. alitretinoin cell differentiation alitretinoin results in increased cell differentiation 1: Homo sapiens Muscles | Cell Line, Tumor
17 genes: AKT1 | CEBPB | CREB1 | FGF1 | FHL1 | HNF4A | MDK | MITF | PDX1 | PRAME | RHOA | RHOB | SEMA6B | SPP1 | TGFB1I1 | VEGFA | VEGFC
1
35. alitretinoin positive regulation of retinoic acid receptor signaling pathway alitretinoin results in increased positive regulation of retinoic acid receptor signaling pathway 1: Homo sapiens Bronchi | Epithelial Cells | Cells, Cultured   1
36. alitretinoin apoptotic process TO-901317 [TO-901317 co-treated with alitretinoin] results in increased apoptotic process 1: Mus musculus Insulin-Secreting Cells | Cell Line
38 genes: AKT1 | APP | BAX | BCL2 | BCL2A1A | BCL2L11 | CAPN3 | CASP3 | CASP7 | CASP8 | CGB3 | DIO3 | FAS | FASTK | GAPDH | IFNG | IGFBP3 | IL1B | IL24 | IRF1 | ITGB2 | LCN2 | MAPK1 | MAPK3 | PARP1 | PRAME | PTEN | RB1 | RHOB | RPS6KA1 | RPS6KB1 | S100A8 | S100A9 | SERPINB9 | TNF | TNFRSF10A | TNFRSF10B | TNFSF10
1
37. alitretinoin cell cycle alitretinoin results in decreased cell cycle 1: Homo sapiens Pancreas | Cell Line, Tumor
14 genes: CCNA2 | CCND3 | CDKN1A | CDKN1B | CDKN1C | KLK10 | KRT18 | MAPK1 | MAPK3 | NEDD9 | RB1 | RHOA | RPS6KA1 | RPS6KB1
1
38. alitretinoin positive regulation of G1/S transition of mitotic cell cycle INS | PDGFB alitretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased positive regulation of G1/S transition of mitotic cell cycle] 1: Homo sapiens Coronary Vessels | Muscle, Smooth, Vascular | Cells, Cultured
2 genes: ANXA1 | TERT
1
39. alitretinoin cholesterol efflux 22-hydroxycholesterol | APOA1 [22-hydroxycholesterol co-treated with alitretinoin] promotes the reaction [APOA1 protein results in increased cholesterol efflux] 2: Homo sapiens | Rattus norvegicus Fetus | Astrocytes | Cells, Cultured
5 genes: ABCA1 | ABCG1 | APOA1 | APOA2 | SCARB1
1
40. alitretinoin cell proliferation alitretinoin results in decreased cell proliferation 1: Homo sapiens Keratinocytes | Cell Line
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
41. alitretinoin cell proliferation alitretinoin results in increased cell proliferation 1: Homo sapiens Keratinocytes | Cells, Cultured
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
42. alitretinoin cell proliferation TO-901317 [TO-901317 co-treated with alitretinoin] results in decreased cell proliferation 1: Mus musculus Insulin-Secreting Cells | Cell Line
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
43. alitretinoin L-cystine transport Ro 41-5253 Ro 41-5253 inhibits the reaction [alitretinoin results in decreased L-cystine transport] 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
44. alitretinoin cell proliferation Tretinoin [alitretinoin co-treated with Tretinoin] results in increased cell proliferation 1: Homo sapiens Keratinocytes | Cells, Cultured
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
45. alitretinoin ornithine catabolic process alitretinoin results in decreased ornithine catabolic process 1: Homo sapiens Induced Pluripotent Stem Cells | Cells, Cultured   1
46. alitretinoin apoptotic process seocalcitol seocalcitol inhibits the reaction [alitretinoin results in increased apoptotic process] 1: Homo sapiens Pancreas | Cell Line, Tumor
38 genes: AKT1 | APP | BAX | BCL2 | BCL2A1A | BCL2L11 | CAPN3 | CASP3 | CASP7 | CASP8 | CGB3 | DIO3 | FAS | FASTK | GAPDH | IFNG | IGFBP3 | IL1B | IL24 | IRF1 | ITGB2 | LCN2 | MAPK1 | MAPK3 | PARP1 | PRAME | PTEN | RB1 | RHOB | RPS6KA1 | RPS6KB1 | S100A8 | S100A9 | SERPINB9 | TNF | TNFRSF10A | TNFRSF10B | TNFSF10
1
47. alitretinoin positive regulation of DNA-binding transcription factor activity alitretinoin results in decreased positive regulation of DNA-binding transcription factor activity 1: Homo sapiens Bronchi | Epithelial Cells | Cells, Cultured
15 genes: AKT1 | APP | ESR1 | ESR2 | FOXA1 | IL1B | IL4 | IL5 | IL6 | JUN | PPARG | PPARGC1A | PTEN | SMAD3 | TNF
1
48. alitretinoin apoptotic process CB 1093 CB 1093 inhibits the reaction [alitretinoin results in increased apoptotic process] 1: Homo sapiens Pancreas | Cell Line, Tumor
38 genes: AKT1 | APP | BAX | BCL2 | BCL2A1A | BCL2L11 | CAPN3 | CASP3 | CASP7 | CASP8 | CGB3 | DIO3 | FAS | FASTK | GAPDH | IFNG | IGFBP3 | IL1B | IL24 | IRF1 | ITGB2 | LCN2 | MAPK1 | MAPK3 | PARP1 | PRAME | PTEN | RB1 | RHOB | RPS6KA1 | RPS6KB1 | S100A8 | S100A9 | SERPINB9 | TNF | TNFRSF10A | TNFRSF10B | TNFSF10
1
49. alitretinoin apoptotic process arsenic trioxide alitretinoin promotes the reaction [arsenic trioxide results in increased apoptotic process] 1: Homo sapiens HL-60 Cells
38 genes: AKT1 | APP | BAX | BCL2 | BCL2A1A | BCL2L11 | CAPN3 | CASP3 | CASP7 | CASP8 | CGB3 | DIO3 | FAS | FASTK | GAPDH | IFNG | IGFBP3 | IL1B | IL24 | IRF1 | ITGB2 | LCN2 | MAPK1 | MAPK3 | PARP1 | PRAME | PTEN | RB1 | RHOB | RPS6KA1 | RPS6KB1 | S100A8 | S100A9 | SERPINB9 | TNF | TNFRSF10A | TNFRSF10B | TNFSF10
1
50. alitretinoin cell proliferation gemcitabine alitretinoin promotes the reaction [gemcitabine results in decreased cell proliferation] 1: Homo sapiens Pancreas | Cell Line, Tumor
20 genes: AKT1 | BAX | BCL2 | CXCL1 | EGFR | EMP1 | FGF1 | GH1 | GLUL | HGF | IGF1 | IL12A | IL12B | MET | PTEN | TACSTD2 | TGFB1 | TNF | TYR | VEGFA
1
1–50 of 711 results.