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Chemical Pyrazolones

1–50 of 58 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 3-hydroxymethylantipyrine xenobiotic metabolic process Dioxins [Dioxins results in increased xenobiotic metabolic process] which results in increased chemical synthesis of 3-hydroxymethylantipyrine 1: Homo sapiens Urine   1
2. Aminopyrine lipid oxidation ammonium ferrous sulfate | Edetic Acid | Enzymes and Coenzymes | Flavin Mononucleotide | NADP | Sodium Chloride Aminopyrine inhibits the reaction [[Flavin Mononucleotide co-treated with Sodium Chloride co-treated with Edetic Acid co-treated with ammonium ferrous sulfate co-treated with NADP metabolite co-treated with Enzymes and Coenzymes] results in increased lipid oxidation] 1: Rattus norvegicus     1
3. Aminopyrine lipid oxidation ammonium ferrous sulfate | Edetic Acid | Enzymes and Coenzymes | Flavin Mononucleotide | Malondialdehyde | NADP | Sodium Chloride Aminopyrine inhibits the reaction [[[Flavin Mononucleotide co-treated with Sodium Chloride co-treated with Edetic Acid co-treated with ammonium ferrous sulfate co-treated with NADP metabolite co-treated with Enzymes and Coenzymes] results in increased lipid oxidation] which results in increased abundance of Malondialdehyde] 1: Rattus norvegicus     1
4. Aminopyrine oxidative demethylation Pargyline [Pargyline results in decreased oxidative demethylation] which results in decreased metabolism of Aminopyrine 1: Mus musculus Brain | Neurons 1 gene: CYP2C8 1
5. Aminopyrine negative regulation of inflammatory response Aminopyrine affects negative regulation of inflammatory response     1
6. Aminopyrine oxidative demethylation Selegiline [Selegiline results in decreased oxidative demethylation] which results in decreased metabolism of Aminopyrine 1: Mus musculus Brain | Neurons 1 gene: CYP2C8 1
7. Ampyrone testosterone biosynthetic process Ampyrone results in decreased testosterone biosynthetic process 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
8. Ampyrone steroid 17-alpha-monooxygenase activity Ampyrone results in decreased steroid 17-alpha-monooxygenase activity 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
9. CC 401 positive regulation of reactive oxygen species biosynthetic process 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole CC 401 inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Homo sapiens Breast | Cell Line, Tumor   1
10. Dipyrone steroid 17-alpha-monooxygenase activity Dipyrone results in decreased steroid 17-alpha-monooxygenase activity 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
11. Dipyrone carbonate dehydratase activity Dipyrone results in decreased carbonate dehydratase activity 1: Ovis aries Blood   1
12. Dipyrone testosterone biosynthetic process Dipyrone results in decreased testosterone biosynthetic process 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
13. Dipyrone progesterone biosynthetic process Dipyrone results in increased progesterone biosynthetic process 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
14. nafazatrom cell proliferation nafazatrom results in decreased cell proliferation 1: Rattus norvegicus Colon   1
15. nafazatrom cell proliferation nafazatrom results in increased cell proliferation 1: Rattus norvegicus Jejunum | Epithelial Cells   1
16. nafazatrom cell proliferation nafazatrom results in increased cell proliferation 1: Rattus norvegicus Colon | Epithelial Cells   1
17. Phenylbutazone cell proliferation IL2 Phenylbutazone inhibits the reaction [IL2 protein results in increased cell proliferation] 1: Mus musculus T-Lymphocytes | Cell Line
3 genes: BCAT1 | TGFB2 | TNF
1
18. Phenylbutazone cell proliferation Amino Acids, Peptides, and Proteins Phenylbutazone inhibits the reaction [Amino Acids, Peptides, and Proteins results in increased cell proliferation] 1: Mus musculus T-Lymphocytes | Cell Line
3 genes: BCAT1 | TGFB2 | TNF
1
19. Phenylbutazone apoptotic cell clearance Phenylbutazone results in increased apoptotic cell clearance 1: Mus musculus Macrophages | Cell Line 1 gene: HAVCR1 1
20. Phenylbutazone positive regulation of urine volume Alprostadil Phenylbutazone inhibits the reaction [Alprostadil results in increased positive regulation of urine volume] 1: Canis lupus familiaris Kidney   1
21. phenylmethylpyrazolone apoptotic chromosome condensation Carbon Monoxide phenylmethylpyrazolone inhibits the reaction [Carbon Monoxide results in increased apoptotic chromosome condensation] 1: Rattus norvegicus Brain   1
22. phenylmethylpyrazolone positive regulation of glutathione peroxidase activity APP phenylmethylpyrazolone inhibits the reaction [APP protein modified form results in decreased positive regulation of glutathione peroxidase activity] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
23. phenylmethylpyrazolone positive regulation of superoxide dismutase activity APP phenylmethylpyrazolone inhibits the reaction [APP protein modified form results in decreased positive regulation of superoxide dismutase activity] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured 1 gene: TNF 1
24. phenylmethylpyrazolone positive regulation of superoxide dismutase activity Rotenone phenylmethylpyrazolone inhibits the reaction [Rotenone results in decreased positive regulation of superoxide dismutase activity] 1: Rattus norvegicus Pars Compacta 1 gene: TNF 1
25. phenylmethylpyrazolone lipid oxidation Cisplatin | Thiobarbituric Acid Reactive Substances phenylmethylpyrazolone inhibits the reaction [[Cisplatin results in increased lipid oxidation] which results in increased abundance of Thiobarbituric Acid Reactive Substances] 1: Mus musculus Kidney   1
26. phenylmethylpyrazolone cell proliferation benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [phenylmethylpyrazolone analog results in decreased cell proliferation] 1: Homo sapiens Esophagus | Cell Line, Tumor
8 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | TNF | VEGFA
1
27. phenylmethylpyrazolone positive regulation of apoptotic process Paraquat phenylmethylpyrazolone inhibits the reaction [Paraquat results in increased positive regulation of apoptotic process] 1: Rattus norvegicus Cells
25 genes: AKT1 | BAX | CASP12 | CASP3 | CASP8 | CASP9 | DAXX | FADD | HIF1A | HMOX1 | IFNG | IL1B | IL6 | MAP3K5 | MAPK8 | MMP2 | MMP9 | NGF | NOS2 | NOS3 | RELA | SOD1 | TGFB1 | TNF | WDR35
1
28. phenylmethylpyrazolone glutathione metabolic process Glutathione [phenylmethylpyrazolone affects glutathione metabolic process] which results in increased abundance of Glutathione 1: Mus musculus Brain
2 genes: SOD1 | SOD2
1
29. phenylmethylpyrazolone glutathione metabolic process Rotenone phenylmethylpyrazolone inhibits the reaction [Rotenone affects glutathione metabolic process] 1: Rattus norvegicus Pars Compacta
2 genes: SOD1 | SOD2
1
30. phenylmethylpyrazolone apoptotic process phenylmethylpyrazolone analog results in increased apoptotic process 1: Homo sapiens Esophagus | Cell Line, Tumor
21 genes: AKT1 | APP | BAX | BCL2 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CYCS | DAXX | ERN1 | FADD | HMOX1 | IFNG | IL1B | MAP3K5 | NCF1 | NFKBIA | PARP1 | TNF
1
31. phenylmethylpyrazolone reactive oxygen species metabolic process cobaltous chloride phenylmethylpyrazolone inhibits the reaction [cobaltous chloride results in increased reactive oxygen species metabolic process] 1: Homo sapiens Trophoblasts | Cell Line
6 genes: BCL2 | EPHX2 | NDUFS1 | NDUFS4 | SOD1 | SOD2
1
32. phenylmethylpyrazolone membrane lipid catabolic process Streptozocin phenylmethylpyrazolone inhibits the reaction [Streptozocin results in increased membrane lipid catabolic process] 1: Mus musculus Pancreas   1
33. phenylmethylpyrazolone positive regulation of neuron apoptotic process Carbon Monoxide phenylmethylpyrazolone inhibits the reaction [Carbon Monoxide results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Neocortex
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
34. phenylmethylpyrazolone cell proliferation benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [phenylmethylpyrazolone analog results in decreased cell proliferation] 1: Homo sapiens Esophagus | Cell Line, Tumor
8 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | TNF | VEGFA
1
35. phenylmethylpyrazolone cell proliferation phenylmethylpyrazolone analog affects cell proliferation 1: Homo sapiens Stomach | Epithelial Cells | Cell Line
8 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | TNF | VEGFA
1
36. phenylmethylpyrazolone positive regulation of neuron apoptotic process Carbon Monoxide phenylmethylpyrazolone inhibits the reaction [Carbon Monoxide results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Hippocampus
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
37. phenylmethylpyrazolone lipid oxidation APP | Malondialdehyde phenylmethylpyrazolone inhibits the reaction [[APP protein modified form results in increased lipid oxidation] which results in increased abundance of Malondialdehyde] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
38. phenylmethylpyrazolone lipid oxidation APP phenylmethylpyrazolone inhibits the reaction [APP protein modified form results in increased lipid oxidation] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
39. phenylmethylpyrazolone positive regulation of neuron apoptotic process Carbon Monoxide phenylmethylpyrazolone inhibits the reaction [Carbon Monoxide results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Corpus Striatum
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
40. phenylmethylpyrazolone glutathione metabolic process Glutathione | Rotenone phenylmethylpyrazolone inhibits the reaction [[Rotenone affects glutathione metabolic process] which results in decreased abundance of Glutathione] 1: Rattus norvegicus Pars Compacta
2 genes: SOD1 | SOD2
1
41. phenylmethylpyrazolone apoptotic process benzyloxycarbonyl-valyl-alanyl-aspartic acid benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [phenylmethylpyrazolone analog results in increased apoptotic process] 1: Homo sapiens Esophagus | Cell Line, Tumor
21 genes: AKT1 | APP | BAX | BCL2 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CYCS | DAXX | ERN1 | FADD | HMOX1 | IFNG | IL1B | MAP3K5 | NCF1 | NFKBIA | PARP1 | TNF
1
42. phenylmethylpyrazolone reactive oxygen species metabolic process phenylmethylpyrazolone analog results in increased reactive oxygen species metabolic process 1: Homo sapiens Esophagus | Cell Line, Tumor
6 genes: BCL2 | EPHX2 | NDUFS1 | NDUFS4 | SOD1 | SOD2
1
43. phenylmethylpyrazolone positive regulation of oxidative stress-induced neuron death phenylmethylpyrazolone results in decreased positive regulation of oxidative stress-induced neuron death 1: Mus musculus Brain   1
44. phenylmethylpyrazolone reactive oxygen species metabolic process Acetylcysteine Acetylcysteine inhibits the reaction [phenylmethylpyrazolone analog results in increased reactive oxygen species metabolic process] 1: Homo sapiens Esophagus | Cell Line, Tumor
6 genes: BCL2 | EPHX2 | NDUFS1 | NDUFS4 | SOD1 | SOD2
1
45. phenylmethylpyrazolone positive regulation of nitric oxide biosynthetic process phenylmethylpyrazolone results in decreased positive regulation of nitric oxide biosynthetic process 1: Mus musculus Brain
8 genes: AGTR2 | AKT1 | ICAM1 | IFNG | IL1B | IL6 | SOD2 | TNF
1
46. phenylmethylpyrazolone angiogenesis cobaltous chloride phenylmethylpyrazolone inhibits the reaction [cobaltous chloride results in decreased angiogenesis] 1: Homo sapiens Human Umbilical Vein Endothelial Cells
10 genes: CASP8 | CCL12 | CCL2 | CXCL8 | FLT1 | HIF1A | HMOX1 | MMP2 | NOS3 | VEGFA
1
47. phenylmethylpyrazolone neuron death SLC1A1 phenylmethylpyrazolone inhibits the reaction [SLC1A1 gene mutant form results in increased neuron death] 1: Mus musculus Retinal Ganglion Cells 1 gene: CXCL2 1
48. phenylmethylpyrazolone cell proliferation phenylmethylpyrazolone analog results in decreased cell proliferation 1: Homo sapiens Esophagus | Cell Line, Tumor
8 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | TNF | VEGFA
1
49. phenylmethylpyrazolone musculoskeletal movement Apomorphine | Rotenone phenylmethylpyrazolone inhibits the reaction [Rotenone promotes the reaction [Apomorphine results in increased musculoskeletal movement]] 1: Rattus norvegicus     1
50. phenylmethylpyrazolone glutathione metabolic process phenylmethylpyrazolone affects glutathione metabolic process 1: Mus musculus Brain
2 genes: SOD1 | SOD2
1
1–50 of 58 results.