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Chemical Pyrazolones

1–50 of 58 results.
  Chemical Phenotype Co-Mentioned Terms Interaction Organisms Anatomy Inference Network References
1. 3-hydroxymethylantipyrine xenobiotic metabolic process Dioxins [Dioxins results in increased xenobiotic metabolic process] which results in increased chemical synthesis of 3-hydroxymethylantipyrine 1: Homo sapiens Urine   1
2. Aminopyrine negative regulation of inflammatory response Aminopyrine affects negative regulation of inflammatory response     1
3. Aminopyrine oxidative demethylation Selegiline [Selegiline results in decreased oxidative demethylation] which results in decreased metabolism of Aminopyrine 1: Mus musculus Brain | Neurons 1 gene: CYP2C8 1
4. Aminopyrine oxidative demethylation Pargyline [Pargyline results in decreased oxidative demethylation] which results in decreased metabolism of Aminopyrine 1: Mus musculus Brain | Neurons 1 gene: CYP2C8 1
5. Aminopyrine lipid oxidation ammonium ferrous sulfate | Edetic Acid | Enzymes and Coenzymes | Flavin Mononucleotide | NADP | Sodium Chloride Aminopyrine inhibits the reaction [[Flavin Mononucleotide co-treated with Sodium Chloride co-treated with Edetic Acid co-treated with ammonium ferrous sulfate co-treated with NADP metabolite co-treated with Enzymes and Coenzymes] results in increased lipid oxidation] 1: Rattus norvegicus     1
6. Aminopyrine lipid oxidation ammonium ferrous sulfate | Edetic Acid | Enzymes and Coenzymes | Flavin Mononucleotide | Malondialdehyde | NADP | Sodium Chloride Aminopyrine inhibits the reaction [[[Flavin Mononucleotide co-treated with Sodium Chloride co-treated with Edetic Acid co-treated with ammonium ferrous sulfate co-treated with NADP metabolite co-treated with Enzymes and Coenzymes] results in increased lipid oxidation] which results in increased abundance of Malondialdehyde] 1: Rattus norvegicus     1
7. Ampyrone testosterone biosynthetic process Ampyrone results in decreased testosterone biosynthetic process 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
8. Ampyrone steroid 17-alpha-monooxygenase activity Ampyrone results in decreased steroid 17-alpha-monooxygenase activity 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
9. CC 401 positive regulation of reactive oxygen species biosynthetic process 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole CC 401 inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Homo sapiens Breast | Cell Line, Tumor   1
10. Dipyrone carbonate dehydratase activity Dipyrone results in decreased carbonate dehydratase activity 1: Ovis aries Blood   1
11. Dipyrone testosterone biosynthetic process Dipyrone results in decreased testosterone biosynthetic process 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
12. Dipyrone progesterone biosynthetic process Dipyrone results in increased progesterone biosynthetic process 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
13. Dipyrone steroid 17-alpha-monooxygenase activity Dipyrone results in decreased steroid 17-alpha-monooxygenase activity 1: Homo sapiens Adrenal Glands | Cell Line, Tumor   1
14. Edaravone membrane lipid catabolic process Streptozocin Edaravone inhibits the reaction [Streptozocin results in increased membrane lipid catabolic process] 1: Mus musculus Pancreas   1
15. Edaravone reactive oxygen species metabolic process cobaltous chloride Edaravone inhibits the reaction [cobaltous chloride results in increased reactive oxygen species metabolic process] 1: Homo sapiens Trophoblasts | Cell Line
6 genes: BCL2 | EPHX2 | NDUFS1 | NDUFS4 | SOD1 | SOD2
1
16. Edaravone angiogenesis cobaltous chloride Edaravone inhibits the reaction [cobaltous chloride results in decreased angiogenesis] 1: Homo sapiens Human Umbilical Vein Endothelial Cells
10 genes: CASP8 | CCL12 | CCL2 | CXCL8 | FLT1 | HIF1A | HMOX1 | MMP2 | NOS3 | VEGFA
1
17. Edaravone cell proliferation Edaravone analog results in decreased cell proliferation 1: Homo sapiens Esophagus | Cell Line, Tumor
7 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | VEGFA
1
18. Edaravone cell proliferation Edaravone analog affects cell proliferation 1: Homo sapiens Stomach | Epithelial Cells | Cell Line
7 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | VEGFA
1
19. Edaravone apoptotic process Edaravone analog results in increased apoptotic process 1: Homo sapiens Esophagus | Cell Line, Tumor
21 genes: AKT1 | APP | BAX | BCL2 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CYCS | DAXX | ERN1 | FADD | HMOX1 | IFNG | IL1B | MAP3K5 | NCF1 | NFKBIA | PARP1 | TNF
1
20. Edaravone cell proliferation benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Edaravone analog results in decreased cell proliferation] 1: Homo sapiens Esophagus | Cell Line, Tumor
7 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | VEGFA
1
21. Edaravone cell proliferation benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [Edaravone analog results in decreased cell proliferation] 1: Homo sapiens Esophagus | Cell Line, Tumor
7 genes: AKT1 | BAX | BCL2 | CXCL1 | NCF1 | TGFB1 | VEGFA
1
22. Edaravone apoptotic process benzyloxycarbonyl-valyl-alanyl-aspartic acid benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Edaravone analog results in increased apoptotic process] 1: Homo sapiens Esophagus | Cell Line, Tumor
21 genes: AKT1 | APP | BAX | BCL2 | CASP12 | CASP3 | CASP7 | CASP8 | CASP9 | CYCS | DAXX | ERN1 | FADD | HMOX1 | IFNG | IL1B | MAP3K5 | NCF1 | NFKBIA | PARP1 | TNF
1
23. Edaravone regulation of mitochondrial membrane potential Edaravone analog affects regulation of mitochondrial membrane potential 1: Homo sapiens Esophagus | Cell Line, Tumor
6 genes: BAX | BCL2 | NDUFS1 | SOD1 | SOD2 | UCP2
1
24. Edaravone reactive oxygen species metabolic process Edaravone analog results in increased reactive oxygen species metabolic process 1: Homo sapiens Esophagus | Cell Line, Tumor
6 genes: BCL2 | EPHX2 | NDUFS1 | NDUFS4 | SOD1 | SOD2
1
25. Edaravone reactive oxygen species metabolic process Acetylcysteine Acetylcysteine inhibits the reaction [Edaravone analog results in increased reactive oxygen species metabolic process] 1: Homo sapiens Esophagus | Cell Line, Tumor
6 genes: BCL2 | EPHX2 | NDUFS1 | NDUFS4 | SOD1 | SOD2
1
26. Edaravone positive regulation of reactive oxygen species biosynthetic process APP Edaravone inhibits the reaction [APP protein modified form results in increased positive regulation of reactive oxygen species biosynthetic process] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured 1 gene: IL4 1
27. Edaravone lipid oxidation APP Edaravone inhibits the reaction [APP protein modified form results in increased lipid oxidation] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
28. Edaravone lipid oxidation APP | Malondialdehyde Edaravone inhibits the reaction [[APP protein modified form results in increased lipid oxidation] which results in increased abundance of Malondialdehyde] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
29. Edaravone positive regulation of superoxide dismutase activity APP Edaravone inhibits the reaction [APP protein modified form results in decreased positive regulation of superoxide dismutase activity] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured 1 gene: TNF 1
30. Edaravone positive regulation of glutathione peroxidase activity APP Edaravone inhibits the reaction [APP protein modified form results in decreased positive regulation of glutathione peroxidase activity] 1: Rattus norvegicus Hippocampus | Neurons | Cells, Cultured   1
31. Edaravone positive regulation of oxidative stress-induced neuron death Edaravone results in decreased positive regulation of oxidative stress-induced neuron death 1: Mus musculus Brain   1
32. Edaravone lipid oxidation Edaravone results in decreased lipid oxidation 1: Mus musculus Brain   1
33. Edaravone positive regulation of nitric oxide biosynthetic process Edaravone results in decreased positive regulation of nitric oxide biosynthetic process 1: Mus musculus Brain
8 genes: AGTR2 | AKT1 | ICAM1 | IFNG | IL1B | IL6 | SOD2 | TNF
1
34. Edaravone glutathione metabolic process Edaravone affects glutathione metabolic process 1: Mus musculus Brain
2 genes: SOD1 | SOD2
1
35. Edaravone glutathione metabolic process Glutathione [Edaravone affects glutathione metabolic process] which results in increased abundance of Glutathione 1: Mus musculus Brain
2 genes: SOD1 | SOD2
1
36. Edaravone lipid oxidation Cisplatin Edaravone inhibits the reaction [Cisplatin results in increased lipid oxidation] 1: Mus musculus Kidney   1
37. Edaravone lipid oxidation Cisplatin | Thiobarbituric Acid Reactive Substances Edaravone inhibits the reaction [[Cisplatin results in increased lipid oxidation] which results in increased abundance of Thiobarbituric Acid Reactive Substances] 1: Mus musculus Kidney   1
38. Edaravone apoptotic chromosome condensation Carbon Monoxide Edaravone inhibits the reaction [Carbon Monoxide results in increased apoptotic chromosome condensation] 1: Rattus norvegicus Brain   1
39. Edaravone nuclear fragmentation involved in apoptotic nuclear change Carbon Monoxide Edaravone inhibits the reaction [Carbon Monoxide results in increased nuclear fragmentation involved in apoptotic nuclear change] 1: Rattus norvegicus Brain   1
40. Edaravone positive regulation of neuron apoptotic process Carbon Monoxide Edaravone inhibits the reaction [Carbon Monoxide results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Neocortex
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
41. Edaravone positive regulation of neuron apoptotic process Carbon Monoxide Edaravone inhibits the reaction [Carbon Monoxide results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Hippocampus
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
42. Edaravone positive regulation of neuron apoptotic process Carbon Monoxide Edaravone inhibits the reaction [Carbon Monoxide results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Corpus Striatum
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
43. Edaravone positive regulation of apoptotic process Paraquat Edaravone inhibits the reaction [Paraquat results in increased positive regulation of apoptotic process] 1: Rattus norvegicus Cells
25 genes: AKT1 | BAX | CASP12 | CASP3 | CASP8 | CASP9 | DAXX | FADD | HIF1A | HMOX1 | IFNG | IL1B | IL6 | MAP3K5 | MAPK8 | MMP2 | MMP9 | NGF | NOS2 | NOS3 | RELA | SOD1 | TGFB1 | TNF | WDR35
1
44. Edaravone neuron death SLC1A1 Edaravone inhibits the reaction [SLC1A1 gene mutant form results in increased neuron death] 1: Mus musculus Retinal Ganglion Cells 1 gene: CXCL2 1
45. Edaravone positive regulation of neuron apoptotic process Rotenone Edaravone inhibits the reaction [Rotenone results in increased positive regulation of neuron apoptotic process] 1: Rattus norvegicus Pars Compacta
8 genes: BAX | CASP3 | CASP9 | CCL3 | IL1B | MAPK8 | PRNP | TNF
1
46. Edaravone positive regulation of superoxide dismutase activity Rotenone Edaravone inhibits the reaction [Rotenone results in decreased positive regulation of superoxide dismutase activity] 1: Rattus norvegicus Pars Compacta 1 gene: TNF 1
47. Edaravone glutathione metabolic process Rotenone Edaravone inhibits the reaction [Rotenone affects glutathione metabolic process] 1: Rattus norvegicus Pars Compacta
2 genes: SOD1 | SOD2
1
48. Edaravone glutathione metabolic process Glutathione | Rotenone Edaravone inhibits the reaction [[Rotenone affects glutathione metabolic process] which results in decreased abundance of Glutathione] 1: Rattus norvegicus Pars Compacta
2 genes: SOD1 | SOD2
1
49. Edaravone musculoskeletal movement Apomorphine | Rotenone Edaravone inhibits the reaction [Rotenone promotes the reaction [Apomorphine results in increased musculoskeletal movement]] 1: Rattus norvegicus     1
50. nafazatrom cell proliferation nafazatrom results in increased cell proliferation 1: Rattus norvegicus Jejunum | Epithelial Cells   1
1–50 of 58 results.