These are exposure studies associated with the disease and all of its children.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Applebaum KM, et al. (2007).||We found increased basal cell carcinoma risk associated with high arsenic exposure among homozygous variants in nucleotide excision repair gene XPA; in subjects with two ERCC2 polymorphisms, there was a 2-fold increased risk of squamous cell carcinoma associated with elevated arsenic.||genetics||Arsenic||Subjects with gene influence:ERCC2 | Subjects with gene influence:XPA||United States||Details||Carcinoma, Basal Cell | Carcinoma, Squamous Cell|
|2.||Heck JE, et al. (2009).||This study supports the possibility of an increased risk of specific lung cancer histologic types (small-cell and squamous-cell carcinoma) at lower levels of arsenic exposure, as measured from toenail.||Arsenic||Controls for disease:Lung Neoplasms | Subjects with disease:Lung Neoplasms||United States||nail||Arsenic||Details||Carcinoma, Squamous Cell | Small Cell Lung Carcinoma|
|3.||Tseng CY, et al. (2012).||The current study suggests that Sulfur Dioxide exposure as an air pollutant may increase female lung cancer incidence and the associations with female lung cancer is much stronger for squamous cell carcinoma than for adenocarcinoma.||Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide||Subjects with disease:Lung Neoplasms||China||air||Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide||Details||Adenocarcinoma | Carcinoma, Squamous Cell|
|4.||Barros-Dios JM, et al. (2012).||The presence of airborne radon even at low concentrations poses a risk of developing lung cancer, with tobacco habit increasing considerably this risk.||tobacco||Radon||Controls for disease:Lung Neoplasms | Subjects with disease:Lung Neoplasms | Study subjects||Spain||Radon||Details||Adenocarcinoma | Carcinoma, Large Cell | Carcinoma, Squamous Cell | Lung Neoplasms | Small Cell Lung Carcinoma|
|5.||Leng S, et al. (2015).||Saccomanno Uranium Miner Cohort||An IL6 promoter variant was associated with lung cancer in uranium miners (exposed to radon) and never smokers in two external study populations; the associations are strongly supported by the functional relevance that the IL6 promoter SNP affects basal expression and carcinogen-induced IL6 secretion.||genetics||Radon||Controls for disease:Carcinoma, Squamous Cell | Subjects with disease:Carcinoma, Squamous Cell | Controls for disease:Lung Neoplasms | Subjects with disease:Lung Neoplasms | Workers||United States||Details||Carcinoma, Squamous Cell | Lung Neoplasms|
|6.||Rafiq R, et al. (2016).||Our findings indicate increased risk of esophageal squamous cell carcinoma due to secondhand smoking exposure in dose-dependent manner.||socioeconomic status | tobacco||Tobacco Smoke Pollution||Controls for disease:Esophageal Squamous Cell Carcinoma | Subjects with disease:Esophageal Squamous Cell Carcinoma||India||Details||Esophageal Squamous Cell Carcinoma|