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Disease Hepatomegaly

These diseases have comparable sets of interacting chemicals and genes to Hepatomegaly.

Via chemical associations

Similarity Index Common
Interacting
Chemicals
Fatty Liver 0.18994 0.18994 102
Liver Neoplasms 0.18685 0.18685 108
Chemical and Drug Induced Liver Injury 0.16667 0.16667 222
Liver Diseases 0.16029 0.16029 88
Liver Neoplasms, Experimental 0.15888 0.15888 85
Weight Loss 0.15588 0.15588 106
Prenatal Exposure Delayed Effects 0.1405 0.1405 85
Hepatitis 0.138 0.138 69
Weight Gain 0.13772 0.13772 69
Necrosis 0.13737 0.13737 143
Carcinoma, Hepatocellular 0.13729 0.13729 74
Hyperplasia 0.13358 0.13358 72
Cholestasis 0.13274 0.13274 75
Liver Cirrhosis 0.13118 0.13118 61
Jaundice 0.12836 0.12836 62
Liver Failure, Acute 0.12581 0.12581 58
Kidney Diseases 0.1194 0.1194 112
Drug-Related Side Effects and Adverse Reactions 0.1147 0.1147 96
Edema 0.11271 0.11271 94
Fever 0.11248 0.11248 73

Via marker/mechanism chemical associations

Similarity Index Common
Interacting
Chemicals
Liver Neoplasms 0.19099 0.19099 89
Chemical and Drug Induced Liver Injury 0.17837 0.17837 193
Fatty Liver 0.17742 0.17742 77
Liver Diseases 0.1588 0.1588 74
Weight Loss 0.15838 0.15838 86
Liver Neoplasms, Experimental 0.15625 0.15625 70
Hepatitis 0.1435 0.1435 64
Carcinoma, Hepatocellular 0.14146 0.14146 58
Prenatal Exposure Delayed Effects 0.13953 0.13953 78
Cholestasis 0.13849 0.13849 68
Jaundice 0.13793 0.13793 60
Necrosis 0.13533 0.13533 113
Liver Failure, Acute 0.134 0.134 54
Hyperplasia 0.12445 0.12445 57
Liver Cirrhosis 0.12222 0.12222 44
Kidney Diseases 0.11934 0.11934 87
Edema 0.11925 0.11925 70
Fever 0.11397 0.11397 62
Liver Failure 0.11357 0.11357 41
Precancerous Conditions 0.11224 0.11224 44

Via therapeutic chemical associations

Similarity Index Common
Interacting
Chemicals
Weight Gain 0.18966 0.18966 22
Fatty Liver 0.144 0.144 18
Liver Cirrhosis 0.12821 0.12821 15
Liver Diseases 0.11579 0.11579 11
Hyperlipidemias 0.11404 0.11404 13
Non-alcoholic Fatty Liver Disease 0.10811 0.10811 8
Liver Neoplasms, Experimental 0.1068 0.1068 11
Hyperinsulinism 0.10667 0.10667 8
Cardiotoxicity 0.10448 0.10448 7
Hypercholesterolemia 0.1 0.1 12
Cell Transformation, Neoplastic 0.0989 0.0989 9
Carcinoma, Ehrlich Tumor 0.09722 0.09722 7
Hyperglycemia 0.09581 0.09581 16
Insulin Resistance 0.09028 0.09028 13
Weight Loss 0.0875 0.0875 14
Liver Cirrhosis, Experimental 0.08725 0.08725 13
Diabetic Cardiomyopathies 0.08197 0.08197 5
Skin Neoplasms 0.08182 0.08182 9
Mitochondrial Diseases 0.07937 0.07937 5
Hyperplasia 0.07843 0.07843 8

Via gene associations

Similarity Index Common
Interacting
Genes
Dyslipidemias 0.04688 0.04688 3
Splenomegaly 0.04688 0.04688 3
Lung Injury 0.04545 0.04545 3
Hyperoxia 0.04082 0.04082 2
Splenic Diseases 0.04082 0.04082 2
Hyperpigmentation 0.04 0.04 2
Diabetes Mellitus 0.03947 0.03947 3
Necrosis 0.03846 0.03846 4
Growth Disorders 0.03704 0.03704 3
Fatty Liver 0.03676 0.03676 5
Atrophy 0.03571 0.03571 2
Non-alcoholic Fatty Liver Disease 0.03409 0.03409 3
Cholestasis 0.03356 0.03356 5
Birth Weight 0.03333 0.03333 2
Liver Neoplasms 0.03315 0.03315 6
Cardiomegaly 0.03306 0.03306 4
Hypogonadism 0.03279 0.03279 2
Metabolism, Inborn Errors 0.03175 0.03175 2
Diabetes Mellitus, Experimental 0.03145 0.03145 5
Hyperlipidemias 0.03077 0.03077 2

Via marker/mechanism gene associations

Similarity Index Common
Interacting
Genes
Splenomegaly 0.04918 0.04918 3
Hyperoxia 0.04348 0.04348 2
Splenic Diseases 0.04348 0.04348 2
Hyperpigmentation 0.04255 0.04255 2
Diabetes Mellitus 0.04167 0.04167 3
Growth Disorders 0.03896 0.03896 3
Atrophy 0.03846 0.03846 2
Non-alcoholic Fatty Liver Disease 0.03659 0.03659 3
Lung Injury 0.03636 0.03636 2
Liver Neoplasms 0.03593 0.03593 6
Hypogonadism 0.03571 0.03571 2
Birth Weight 0.03509 0.03509 2
Dyslipidemias 0.0339 0.0339 2
Diabetes Mellitus, Experimental 0.03378 0.03378 5
Necrosis 0.03371 0.03371 3
Metabolism, Inborn Errors 0.03333 0.03333 2
Metabolic Syndrome 0.03125 0.03125 2
Infertility, Female 0.02857 0.02857 2
Cholestasis 0.02817 0.02817 4
Liver Diseases 0.02778 0.02778 3

Via therapeutic gene associations

Similarity Index Common
Interacting
Genes
Glucose Intolerance 0.125 0.125 1
Fatty Liver 0.08333 0.08333 1
Lung Injury 0.08333 0.08333 1
Obesity 0.07143 0.07143 1
Neoplasm Metastasis 0.05556 0.05556 1
Pancreatic Neoplasms 0.05556 0.05556 1
Neoplasm Invasiveness 0.04167 0.04167 1
Chemical and Drug Induced Liver Injury 0.03333 0.03333 1