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Disease Hepatomegaly

These diseases have comparable sets of interacting chemicals and genes to Hepatomegaly.

Via chemical associations

Similarity Index Common
Interacting
Chemicals
Liver Neoplasms 0.1876 0.1876 112
Fatty Liver 0.17882 0.17882 103
Chemical and Drug Induced Liver Injury 0.17178 0.17178 235
Weight Loss 0.16366 0.16366 118
Liver Neoplasms, Experimental 0.16065 0.16065 89
Liver Diseases 0.15965 0.15965 91
Prenatal Exposure Delayed Effects 0.14422 0.14422 91
Necrosis 0.1434 0.1434 152
Carcinoma, Hepatocellular 0.14183 0.14183 79
Hepatitis 0.1368 0.1368 71
Cholestasis 0.13527 0.13527 79
Weight Gain 0.13494 0.13494 73
Jaundice 0.132 0.132 66
Hyperplasia 0.12966 0.12966 73
Kidney Diseases 0.12759 0.12759 123
Liver Cirrhosis 0.12757 0.12757 62
Liver Failure, Acute 0.12266 0.12266 59
Hypertrophy 0.11607 0.11607 52
Drug-Related Side Effects and Adverse Reactions 0.11525 0.11525 99
Inflammation 0.11391 0.11391 104

Via marker/mechanism chemical associations

Similarity Index Common
Interacting
Chemicals
Liver Neoplasms 0.19287 0.19287 92
Chemical and Drug Induced Liver Injury 0.18132 0.18132 200
Fatty Liver 0.1692 0.1692 78
Weight Loss 0.16637 0.16637 94
Liver Diseases 0.16176 0.16176 77
Liver Neoplasms, Experimental 0.16157 0.16157 74
Prenatal Exposure Delayed Effects 0.14609 0.14609 84
Carcinoma, Hepatocellular 0.14524 0.14524 61
Hepatitis 0.14223 0.14223 65
Cholestasis 0.13972 0.13972 70
Jaundice 0.13933 0.13933 62
Necrosis 0.13797 0.13797 117
Liver Failure, Acute 0.13012 0.13012 54
Hyperplasia 0.12288 0.12288 58
Kidney Diseases 0.12182 0.12182 91
Liver Cirrhosis 0.12097 0.12097 45
Edema 0.11881 0.11881 72
Hypertrophy 0.11528 0.11528 43
Acute Kidney Injury 0.11433 0.11433 79
Precancerous Conditions 0.11386 0.11386 46

Via therapeutic chemical associations

Via gene associations

Similarity Index Common
Interacting
Genes
Hepatic Insufficiency 0.15517 0.15517 9
Cholestasis, Extrahepatic 0.1125 0.1125 9
Liver Cirrhosis, Biliary 0.1 0.1 9
Pulmonary Disease, Chronic Obstructive 0.05952 0.05952 5
Cholestasis 0.05806 0.05806 9
Non-alcoholic Fatty Liver Disease 0.05556 0.05556 6
Diabetes Mellitus, Experimental 0.05488 0.05488 9
Diabetic Nephropathies 0.05435 0.05435 5
Necrosis 0.05405 0.05405 6
Ureteral Obstruction 0.05195 0.05195 4
Kidney Failure, Chronic 0.05102 0.05102 5
Kidney Diseases 0.0493 0.0493 7
Occupational Diseases 0.04615 0.04615 3
Diabetic Angiopathies 0.04286 0.04286 3
Liver Neoplasms 0.04255 0.04255 8
Hypertension 0.04132 0.04132 10
Acute Kidney Injury 0.0411 0.0411 6
Dyslipidemias 0.0411 0.0411 3
Fatty Liver 0.0411 0.0411 6
Hyperlipidemias 0.0411 0.0411 3
Splenomegaly 0.0411 0.0411 3

Via marker/mechanism gene associations

Similarity Index Common
Interacting
Genes
Hepatic Insufficiency 0.16364 0.16364 9
Cholestasis, Extrahepatic 0.11688 0.11688 9
Liver Cirrhosis, Biliary 0.10345 0.10345 9
Pulmonary Disease, Chronic Obstructive 0.06173 0.06173 5
Diabetes Mellitus, Experimental 0.05882 0.05882 9
Non-alcoholic Fatty Liver Disease 0.05882 0.05882 6
Kidney Failure, Chronic 0.05435 0.05435 5
Ureteral Obstruction 0.05405 0.05405 4
Occupational Diseases 0.04839 0.04839 3
Cholestasis 0.04698 0.04698 7
Acute Kidney Injury 0.04615 0.04615 6
Diabetic Angiopathies 0.04615 0.04615 3
Liver Neoplasms 0.04598 0.04598 8
Splenomegaly 0.04286 0.04286 3
Hyperglycemia 0.04225 0.04225 3
Atherosclerosis 0.04167 0.04167 4
Metabolic Syndrome 0.04167 0.04167 3
Sepsis 0.04167 0.04167 3
Infertility, Male 0.04124 0.04124 4
Necrosis 0.04124 0.04124 4

Via therapeutic gene associations

Similarity Index Common
Interacting
Genes
Glucose Intolerance 0.11111 0.11111 1
Fatty Liver 0.08333 0.08333 1
Lung Injury 0.08333 0.08333 1
Obesity 0.07143 0.07143 1
Pancreatic Neoplasms 0.05556 0.05556 1
Neoplasm Metastasis 0.05 0.05 1
Neoplasm Invasiveness 0.04 0.04 1
Chemical and Drug Induced Liver Injury 0.0303 0.0303 1