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Disease Disorders of Environmental Origin

These phenotypes are associated with Disorders of Environmental Origin or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 859 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. DNA damage response, detection of DNA damage Disorders of Environmental Origin Inferred via 5 chemicals: Acrolein | Formaldehyde | metolachlor | Ozone | Particulate Matter   34
2. cell proliferation Disorders of Environmental Origin Inferred via 5 chemicals: Acrolein | Formaldehyde | metolachlor | Ozone | Particulate Matter   31
3. response to oxidative stress Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 22
4. reactive oxygen species biosynthetic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   22
5. apoptotic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   61
6. cell death Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   22
7. inflammatory response Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   16
8. negative regulation of cell proliferation Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | metolachlor | Particulate Matter   7
9. membrane lipid catabolic process Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Hexachlorocyclohexane | Tobacco Smoke Pollution   25
10. response to oxidative stress Disorders of Environmental Origin Inferred via 4 chemicals: 1,6-hexamethylene diisocyanate | Acrolein | Ozone | Particulate Matter   9
11. cell death Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   17
12. apoptotic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   20
13. glutathione peroxidase activity Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   4
14. positive regulation of cell death Multiple Chemical Sensitivity Inferred via 4 chemicals: Acetaminophen | Aspirin | Pentachlorophenol | Tobacco Smoke Pollution   22
15. glutathione biosynthetic process Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   10
16. positive regulation of cell death Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Chlorine | Formaldehyde | Particulate Matter   19
17. superoxide dismutase activity Disorders of Environmental Origin Inferred via 4 chemicals: Acrolein | Formaldehyde | Ozone | Particulate Matter   6
18. regulation of mitochondrial membrane potential Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 13
19. regulation of blood pressure Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 12
20. glutathione metabolic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 15
21. positive regulation of JNK cascade Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution   7
22. cell proliferation Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   44
23. protein oxidation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   4
24. leukocyte chemotaxis Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
25. nitric oxide biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Formaldehyde | Particulate Matter   4
26. positive regulation of reactive oxygen species biosynthetic process Disorders of Environmental Origin Inferred via 3 chemicals: Formaldehyde | Ozone | Particulate Matter   10
27. positive regulation of apoptotic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   9
28. cell cycle Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   15
29. lipid catabolic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   14
30. regulation of heart rate Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   6
31. lipid oxidation Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   9
32. positive regulation of collagen biosynthetic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Aspirin | Tobacco Smoke Pollution   4
33. glutathione biosynthetic process Multiple Chemical Sensitivity Inferred via 3 chemicals: Acetaminophen | Hexachlorocyclohexane | Tobacco Smoke Pollution   28
34. lipid oxidation Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Ozone | Particulate Matter   6
35. positive regulation of cytokine production involved in inflammatory response Disorders of Environmental Origin Inferred via 3 chemicals: Formaldehyde | Ozone | Particulate Matter   4
36. cell migration Disorders of Environmental Origin Inferred via 3 chemicals: Acrolein | Chlorine | Particulate Matter   5
37. negative regulation of cell proliferation Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 5
38. reactive oxygen species metabolic process Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 10
39. vasodilation Multiple Chemical Sensitivity Inferred via 2 chemicals: Aspirin | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 14
40. mitochondrion organization Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 4
41. superoxide dismutase activity Multiple Chemical Sensitivity Inferred via 2 chemicals: Acetaminophen | Tobacco Smoke Pollution Inferred via 1 gene: SOD2 13
42. positive regulation of autophagosome assembly Disorders of Environmental Origin Inferred via 2 chemicals: Formaldehyde | Particulate Matter   3
43. positive regulation of monocyte extravasation Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   3
44. swimming behavior Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   2
45. positive regulation of neutrophil extravasation Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   4
46. lymphocyte chemotaxis Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   4
47. glutathione metabolic process Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   5
48. detection of oxidative stress Disorders of Environmental Origin Inferred via 2 chemicals: Acrolein | Particulate Matter   4
49. positive regulation of cellular response to oxidative stress Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   5
50. DNA methylation Disorders of Environmental Origin Inferred via 2 chemicals: Ozone | Particulate Matter   7
1–50 of 859 results.