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Disease Lung Diseases

These are exposure studies associated with the disease and all of its children.

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1–50 of 183 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Jung KH, et al. (2014). Columbia Center for Children's Environmental Health (CCCEH) Obese young children may be more likely to develop asthma in association with greater exposure to polycyclic aromatic hydrocarbons, and methylphenanthrenes in particular, than non-obese children. body mass index | disease | sex 1-methylphenanthrene | 2-methylphenanthrene | phenanthrene | pyrene Children | Controls for disease:Obesity | Subjects with disease:Obesity United States air 1-methylphenanthrene | 2-methylphenanthrene | phenanthrene | pyrene Details Asthma
2. Allen JG, et al. (2016). Our findings confirm the presence of diacetyl and other flavoring chemicals in flavored e-cigarettes. 2,3-pentanedione | Acetoin | Diacetyl United States e-cigarette 2,3-pentanedione | Acetoin | Diacetyl Details Bronchiolitis Obliterans
3. Hoppin JA, et al. (2007). Agricultural Health Study (AHS) These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence. 2,4,5-Trichlorophenoxyacetic Acid | Carbaryl | Carbofuran | chlorimuron ethyl | DDT | Diazinon | Dichlorvos | fenoprop | Heptachlor | Malathion | Permethrin Workers United States Details Agricultural Workers' Diseases | Bronchitis, Chronic
4. Hoppin JA, et al. (2002). Agricultural Health Study (AHS) Prevalence of wheeze was associated with individual pesticides independent of animals, crops, and grains. disease 2,4-Dichlorophenoxyacetic Acid | alachlor | Aldicarb | aluminum phosphide | Atrazine | Benomyl | butylate | Captan | Carbaryl | Carbofuran | chlorimuron ethyl | Chlorpyrifos | Coumaphos | cyanazine | Diazinon | Dicamba | Dichlorvos | EPTC | Fonofos | glyphosate | imazethapyr | Lindane | Malathion | Maneb | metalaxyl | metolachlor | metribuzin | Paraquat | Parathion | pendimethalin | Permethrin | Petroleum | Phorate | terbufos | tetrachloroisophthalonitrile | Trichlorfon | Trifluralin | Ziram Subjects with disease:Asthma | Subjects with disease:Ige Responsiveness, Atopic | Workers United States Details Agricultural Workers' Diseases | Respiratory Sounds
5. Hoppin JA, et al. (2008). Agricultural Health Study (AHS) These findings suggest that pesticides may contribute to atopic asthma, but not nonatopic asthma, among farm women. 2,4-Dichlorophenoxyacetic Acid | Carbamates | Carbaryl | Coumaphos | DDT | glyphosate | Hydrocarbons, Chlorinated | Malathion | metalaxyl | Organophosphates | Parathion | Permethrin | Pesticides | Phorate Study subjects United States Details Agricultural Workers' Diseases | Asthma
6. Elliott L, et al. (2006). National Health and Nutrition Examination Survey (NHANES) Exposure to 1,4-dichlorobenzene (a volatile organic compound related to the use of air fresheners, toilet bowl deodorants, and mothballs) at levels found in the US general population, may result in reduced pulmonary function. 4-dichlorobenzene | Volatile Organic Compounds Study subjects United States blood 1,1,1-trichloroethane | 2-xylene | 3-xylene | 4-dichlorobenzene | 4-xylene | Acetone | Benzene | ethylbenzene | methylethyl ketone | Styrene | Tetrachloroethylene | Toluene Details PULMONARY FUNCTION
7. Kioumourtzoglou MA, et al. (2013). Aerosol Research and Inhalation Epidemiology Study (ARIES) Results suggest that week-long exposures to traffic-related, primary organic species are associated with increased rate of total and cause-specific cardiovascular disease emergency hospital admissions. 9-fluorenone | acenaphthylene | benzo(b)fluoranthene | benzo(e)pyrene | benzo(k)fluoranthene | chrysene | Cyclohexane | cyclopenta(c,d)pyrene | docosane | dotriacontane | fluoranthene | hentriacontane | n-heneicosane | nonacosane | n-pentacosane | n-tricosane | octacosane | Particulate Matter | phenanthrene | pyrene | retene | Soot | tetracosane | tritriacontane Subjects with disease:Cardiovascular Diseases | Subjects with disease:Coronary Disease | Subjects with disease:Myocardial Infarction | Subjects with disease:Pulmonary Disease, Chronic Obstructive United States air 9-fluorenone | acenaphthylene | benzo(b)fluoranthene | benzo(e)pyrene | benzo(k)fluoranthene | chrysene | Cyclohexane | cyclopenta(c,d)pyrene | docosane | dotriacontane | fluoranthene | hentriacontane | n-heneicosane | nonacosane | n-pentacosane | n-tricosane | octacosane | phenanthrene | pyrene | retene | Soot | tetracosane | tritriacontane Details Cardiovascular Diseases | Coronary Disease | Myocardial Infarction | Pulmonary Disease, Chronic Obstructive
8. Lerro CC, et al. (2015). Agricultural Health Study (AHS) The associations between acetochlor use and lung cancer, colorectal cancer, melanoma and pancreatic cancer are suggestive; however, the lack of exposure-response trends, small number of exposed cases, and relatively short time between acetochlor use and cancer development prohibit definitive conclusions. acetochlor Workers United States Details Agricultural Workers' Diseases | Colorectal Neoplasms | Lung Neoplasms | Melanoma | Pancreatic Neoplasms
9. Lerro C, et al. (2014). Agricultural Health Study (AHS) The associations between acetochlor and colorectal and lung cancer are novel; however, due to lack of exposure-response trend, small number of exposed cases, and relatively short time between use and cancer development, these findings warrant caution in interpretation and further investigation. acetochlor Workers United States Details Agricultural Workers' Diseases | Colorectal Neoplasms | Lung Neoplasms
10. White N, et al. (2009). International Study of Asthma and Allergies in Childhood (ISAAC) The study showed a measurable health effect, both an excess of asthma symptoms in comparison with the rest of the city, and more frequent wheezing symptoms associated with an index of estimated petrochemical refinery emissions exposure. Air Pollutants Children South Africa Details Asthma
11. Xue X, et al. (2013). The hOGG1 Ser326Cys polymorphism might be associated with the risk of lung adenocarcinoma in Chinese non-smoking females. Furthermore, there is a significant gene-environment association between cooking oil fumes and hOGG1 326 Cys/Cys genotype in lung adenocarcinoma among female non-smokers. genetics Air Pollutants Controls for disease:Adenocarcinoma of lung | Subjects with disease:Adenocarcinoma of lung | Subjects with gene influence:OGG1 China Details Adenocarcinoma of lung
12. Salameh P, et al. (2012). Chronic bronchitis is associated with outdoor air pollution in Lebanon. Air Pollutants Controls for disease:Bronchitis, Chronic | Subjects with disease:Bronchitis, Chronic Lebanon Details Bronchitis, Chronic
13. Liu X, et al. (2012). Our results are consistent with the hypothesis that exposure to air pollution from fuel-fired power plants and volatile compounds coming from hazardous waste sites increases the risk of hospitalization for respiratory diseases. Air Pollutants Study subjects United States Air Pollutants Details Asthma | Pulmonary Disease, Chronic Obstructive | Respiratory Tract Infections
14. Karr C, et al. (2007). Subchronic and chronic particulate matter PM2.5 exposures were associated with increased risk of bronchiolitis hospitalization for infants. Air Pollutants Controls for disease:Bronchiolitis | Subjects with disease:Bronchiolitis | Infants or newborns United States air, outdoor Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter Details Bronchiolitis
15. Schildcrout JS, et al. (2006). Childhood Asthma Management Program (CAMP) This study reports the relation between ambient concentrations of five air pollutants and asthma exacerbations: lags in carbon monoxide and nitrogen dioxide were positively associated with both measures of asthma exacerbation, and the 3-day moving sum of sulfur dioxide levels was marginally related to asthma symptoms, but particulate matter PM10 and ozone were unrelated to exacerbations. Air Pollutants Children Canada|United States air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Asthma
16. Gorai AK, et al. (2016). Our results reveal no significant association between asthma rates and exposure of ambient air pollutants; however, there is a positive correlation between particulate matter PM2.5 and asthma discharge rates and a negative correlation between asthma rates and ozone, but these were not statistically significant, and can be better explained by local weather conditions; the research facilitates identification of hotspots for controlling the most affected populations from further environmental exposure, and for preventing or reducing the health impacts. Air Pollutants Study subjects United States air, ambient Ozone | Particulate Matter Details Asthma
17. Clark NA, et al. (2010). We observed a statistically significantly increased risk of asthma diagnosis with increased early life exposure to carbon monoxide, nitric oxide, nitrogen dioxide, particulate matter (PM10), sulfur dioxide, and black carbon and proximity to point sources. age Air Pollutants Controls for disease:Asthma | Subjects with disease:Asthma Canada Carbon Monoxide | Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Soot | Sulfur Dioxide Details Asthma
18. Ierodiakonou D, et al. (2016). Childhood Asthma Management Program (CAMP) Air pollution adversely influences lung function and methacholine responsiveness in asthmatic children, and treatment with controller medications might not protect but rather worsen the effects of carbon monoxide on methacholine responsiveness. disease Air Pollutants Subjects with disease:Asthma | Children Canada|United States air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Sulfur Dioxide Details response to bronchodilator
19. Bowatte G, et al. (2016). Melbourne Atopy Cohort Study (MACS) Traffic-related air pollution is associated with some respiratory outcomes in carriers of genetic polymorphisms in oxidative stress metabolism genes. genetics Air Pollutants Children | Subjects with gene influence:GSTM1 | Subjects with gene influence:GSTT1 Australia Details Asthma | Respiratory Sounds | Rhinitis, Allergic, Seasonal
20. Velická H, et al. (2015). These results suggest moderately strong associations between air pollutant concentrations and respiratory difficulties among asthmatic children and adolescents. disease Air Pollutants Subjects with disease:Asthma | Children Czech Republic air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Respiratory Sounds
21. Raun LH, et al. (2014). In Houston (Texas), ozone and nitrogen dioxide are important triggers of asthma attacks in a multi-pollutant model, and persons at highest risk are aged 46-66, African Americans, and males. age | race | sex Air Pollutants Subjects with disease:Asthma | Study subjects United States air, ambient Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Asthma
22. Shankardass K, et al. (2009). Children's Health Study (CHS) These results suggest that children from stressful households are more susceptible to the effects of traffic-related pollution and in utero tobacco smoke on the development of asthma. race | socioeconomic status | tobacco Air Pollutants Children United States Nitric Oxide Details Asthma
23. Lundström SL, et al. (2011). Several of the altered oxylipins have known or suspected bronchoprotective or anti-inflammatory effects, suggesting a possible reduced anti-inflammatory response in asthmatics following exposure to subway air. disease Air Pollutants Controls for disease:Asthma | Subjects with disease:Asthma Sweden lung 12,13-epoxy-9- keto-10-octadecenoic acid | 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid | 13-hydroxy-9,11-octadecadienoic acid | 13-Hydroxy-octadecatrienoic acid | 13-oxo-9,11-octadecadienoic acid | 15-hydroxy-5,8,11,13,17-eicosapentaenoic acid | 15-hydroxy-5,8,11,13-eicosatetraenoic acid | 15-hydroxyeicosatrienoic acid | 15-keto-5,8,11,13-eicosatetraenoic acid | 17-hydroxy-4,7,10,13,15,19-docosahexaenoic acid | 5,6-epoxy-8,11,14-eicosatrienoic acid | 5-hydroxy-6,8,11,14-eicosatetraenoic acid | 8,9-epoxyeicosatrienoic acid | 9,10,13-trihydroxyoctadec-11-enoic acid | 9,12,13-trihydroxy-10-octadecenoic acid | 9-hydroxy-10,12-octadecadienoic acid | 9-oxo-10,12-octadecadienoic acid | ALOX15 | Dinoprostone | Leukotriene B4 | PPARG | Prostaglandin D2 | PTGS1 | PTGS2 | Thromboxane B2 Details negative regulation of inflammatory response | oxylipin biosynthetic process
24. Shmool JL, et al. (2016). New York City Community Air Survey (NYCCAS) We leverage highly spatially-refined air pollution data to incorporate individual-level spatial exposure variation in a case-crossover analysis of daily ozone exposure and childhood asthma exacerbation events in New York City; incorporating case-level spatial exposure variation produced small, non-significant increases in excess risk estimates. Air Pollutants Subjects with disease:Asthma | Children United States air, ambient Ozone | Particulate Matter Details
25. Pun VC, et al. (2015). Nurses' Health Study (NHS) Particulate matter in the prior 1 and 12 months is associated with pulmonary embolism risk, and women with underlying health conditions may be more susceptible to pulmonary embolism after particulate matter exposure. sex Air Pollutants Study subjects United States air, ambient Particulate Matter Details Pulmonary Embolism
26. Chen E, et al. (2008). The physical and social environments interacted in predicting both biologic and clinical outcomes in children with asthma, suggesting that when pollution exposure is more modest, vulnerability to asthma exacerbations may be heightened in children with higher chronic stress. Air Pollutants | Nitrogen Dioxide Subjects with disease:Asthma | Children Canada IL13 | IL4 | IL5 | Nitrogen Dioxide Details Asthma
27. Barraza-Villarreal A, et al. (2008). Exposure to particulate matter <= 2.5 microns in aerodynamic diameter resulted in acute airway inflammation and decrease in lung function in both asthmatic and nonasthmatic children. Air Pollutants | Nitrogen Dioxide | Ozone | Particulate Matter Controls for disease:Asthma | Subjects with disease:Asthma | Children Mexico air Nitrogen Dioxide | Ozone | Particulate Matter Details Signs and Symptoms, Respiratory | regulation of inflammatory response
28. Sarnat SE, et al. (2012). The results indicate adverse effects of air pollution on the subclinical respiratory health of asthmatic children in this region and provide preliminary support for the use of air pollution monitors close to schools to track exposure and potential health risk in this population. disease Air Pollutants | Nitrogen Dioxide | Ozone | Particulate Matter | Soot | Vehicle Emissions Subjects with disease:Asthma | Children Mexico|United States air | air, ambient | air, indoor | air, outdoor Nitric Oxide | Nitrogen Dioxide | Ozone | Particulate Matter | Soot Details
29. Thompson AM, et al. (2010). In our analysis, exposure to ambient levels of ozone and sulfur dioxide was positively and significantly associated with a systemic inflammatory response as measured by systemic levels of interleukin 6 (IL6). Air Pollutants | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Controls for disease:Asthma | Subjects with disease:Asthma | Study subjects Canada air | blood | plasma Carbon Monoxide | IL6 | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details interleukin-6 biosynthetic process
30. Beelen R, et al. (2008). Netherlands Cohort Study on Diet and Cancer (NLCS) We found evidence for an association of exposure to black smoke and traffic with lung cancer incidence in people who had never smoked. diet | tobacco Air Pollutants | Nitrogen Dioxide | Particulate Matter | Smoke | Sulfur Dioxide Controls for disease:Lung Neoplasms | Subjects with disease:Lung Neoplasms | Study subjects Netherlands air, ambient Nitrogen Dioxide | Particulate Matter | Smoke | Sulfur Dioxide Details Lung Neoplasms
31. Morgenstern V, et al. (2007). We estimated long-term exposure to traffic-related air pollutants: significant associations were found between particulate matter PM2.5 and sneezing, runny/stuffed nose during the first and second years of life, and between nitrogen dioxide and dry cough at night (or bronchitis) during the first year of life. Air Pollutants | Nitrogen Dioxide | Particulate Matter | Vehicle Emissions Children | Study subjects Germany air, outdoor Nitrogen Dioxide | Particulate Matter Details Bronchitis | Cough | Sneezing
32. Kalappanavar NK, et al. (2012). The study provides a first evidence of the strong association between air pollution and development of airway diseases. Carbon particles in macrophages in the sputum can be used as a marker for air pollution. Air Pollutants | Particulate Matter Children India air | macrophage Carbon | Particulate Matter Details Lung Diseases
33. Pope CA 3RD, et al. (2011). American Cancer Society Cancer Prevention Study II (ACS CPS-II) The exposure-response relationship associated with PM2.5 is qualitatively different for lung cancer versus cardiovascular mortality. At low exposure levels, cardiovascular deaths are projected to account for most of the burden of disease, whereas at high levels of PM2.5, lung cancer becomes proportionately more important. tobacco Air Pollutants | Particulate Matter Study subjects United States cigarette Particulate Matter Details Cardiovascular Diseases | Death | Lung Neoplasms
34. Golini MN, et al. (2014). Living in areas with high Particulate Matter (10) levels due to incinerators was associated with increased morbidity levels for respiratory disorders among men. Air Pollutants | Particulate Matter Study subjects Italy Details Cardiovascular Diseases | Lung Diseases | Pulmonary Disease, Chronic Obstructive
35. Tsuji M, et al. (2012). Interleukin 22 (IL22) mRNA expression in blood samples is a useful biomarker for assessing the adverse health effects of polychlorinated biphenyls on allergic children, especially children with egg hypersensitivity, milk hypersensitivity, and asthma. diet | disease Air Pollutants | Polychlorinated Biphenyls Subjects with disease:Asthma | Children | Subjects with disease:Egg Hypersensitivity | Subjects with disease:Milk Hypersensitivity Japan blood | serum IL22 | Polychlorinated Biphenyls Details
36. Higuchi K, et al. (2012). This study showed that Mt. Sakurajima's volcanic activities increased the mortality of lung cancer and chronic obstructive pulmonary diseases in the Sakurajima-Tarumizu area, which has the largest amount of ashfall from the volcano in its vicinity. Air Pollutants | Silicon Dioxide Study subjects Japan Air Pollutants | Silicon Dioxide Details Death | Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Respiration Disorders
37. Li S, et al. (2011). There is moderately strong evidence of elevated risk of asthma close to major roads obtained in this population-based matched case-control study. socioeconomic status Air Pollutants | Vehicle Emissions Children United States Details Asthma
38. Oyana TJ, et al. (2004). There are 2 implications of the study findings: first, current traffic levels not only contribute to asthma and other respiratory disease exacerbations but may also contribute to high asthma prevalence on Buffalo's West Side in comparison with other Buffalo communities; and second, identification of asthma clusters along busily traveled roadways and the Peace Bridge Complex, in addition to other sites, indicates an etiological link between pollutants and high asthma prevalence rates. Air Pollutants | Vehicle Emissions Controls for disease:Asthma | Subjects with disease:Asthma United States Details Asthma
39. Gruzieva O, et al. (2017). Children, Allergy, Milieu, Stockholm, Epidemiological Survey (BAMSE) Our results indicate alterations in systemic inflammatory cytokine markers in 8-year old children in relation to early-life exposure to the traffic-related air pollutants nitrogen dioxide and particulate matter (PM10), and asthma influences some of the interactions. disease Air Pollutants | Vehicle Emissions Controls for disease:Asthma | Subjects with disease:Asthma | Children Sweden air, ambient | serum CXCL8 | IFNG | IL13 | IL1B | IL2 | IL4 | IL6 | Nitrogen Dioxide | Particulate Matter | TNF Details positive regulation of interleukin-10 secretion | positive regulation of interleukin-6 secretion | positive regulation of tumor necrosis factor production
40. Wier M, et al. (2009). We used our findings regarding traffic-related exposures and health hazards in the area to facilitate community education and action to address transportation-related health burdens on neighborhood residents. Air Pollutants | Vehicle Emissions Study subjects United States Air Pollutants Details Asthma
41. Andersson M, et al. (2011). Obstructive Lung Disease in Northern Sweden (OLIN) This study showed that already at low levels of exposure, vehicle traffic is related to an increased risk of wheeze among children. Air Pollutants | Vehicle Emissions Children Sweden Details Asthma | Respiratory Sounds
42. Sharifian SA, et al. (2011). This study investigates the effects of welding fumes on lung function and respiratory symptoms among welders of an automobile manufacturing plant in Iran. Air Pollutants, Occupational Workers Iran, Islamic Republic of Details Bronchitis, Chronic
43. Valiante DJ, et al. (2004). We examined highway construction trends, silicosis surveillance case data, and environmental exposure data to evaluate the risk of silicosis among highway repair workers. Air Pollutants, Occupational Subjects with disease:Silicosis | Workers United States Details Silicosis
44. Hinson AV, et al. (2014). The prevalence of respiratory symptoms and byssinosis among cotton mill workers in Benin is high and needs prompt attention of health care workers and policymakers. Air Pollutants, Occupational | Dust Workers Benin Details Byssinosis
45. Andreotti G, et al. (2010). Agricultural Health Study (AHS) Using data from the Agricultural Health Study, we examined the association between body mass index (BMI) and the risk of cancer at 17 sites and the interaction between BMI and pesticide use. body mass index | tobacco alachlor | Atrazine | Carbaryl | Carbofuran | chlorimuron ethyl | Chlorpyrifos | cyanazine | DDT | Diazinon | EPTC | Fonofos | glyphosate | Hydrocarbons, Chlorinated | imazethapyr | Malathion | methyl bromide | metolachlor | metribuzin | Organophosphates | pendimethalin | Permethrin | terbufos | Trifluralin Study subjects | Workers United States Details Agricultural Workers' Diseases | Breast Neoplasms | Colonic Neoplasms | Lung Neoplasms
46. Henneberger PK, et al. (2014). Agricultural Health Study (AHS) The findings from this study suggest that use of selected pesticides might be risk factors for exacerbation of symptoms among adult pesticide applicators with active allergic asthma. disease Aldicarb | butylate | cyanazine | glyphosate | metribuzin | Paraquat | pendimethalin Subjects with disease:Asthma | Controls for disease:Hypersensitivity | Subjects with disease:Hypersensitivity | Workers United States Details Agricultural Workers' Diseases | Asthma
47. Hoppin JA, et al. (2007). Agricultural Health Study (AHS) Among farmers, handling silage, high pesticide exposure events, and ever use of organochlorine and carbamate pesticides were associated with farmer's lung in mutually-adjusted models. Aldicarb | Carbamates | DDT | Hydrocarbons, Chlorinated | Lindane | Pesticides Study subjects | Workers United States Details Agricultural Workers' Diseases | Farmer's Lung
48. Purdue MP, et al. (2007). Agricultural Health Study (AHS) Our analysis of data from the Agricultural Health Study cohort suggests that, overall, use of organochlorine insecticides was not related to cancer risk. We did, however, observe associations among specific chemicals, some of which (lindane and NHL, chlordane/heptachlor and leukemia) are supported by previously published studies and warrant further investigation. Aldrin | Chlordan | DDT | Dieldrin | Heptachlor | Lindane | Toxaphene Workers United States Details Agricultural Workers' Diseases | Colonic Neoplasms | Leukemia | Lung Neoplasms | Lymphoma, Non-Hodgkin | Melanoma | Neoplasms | Rectal Neoplasms
49. Wu M, et al. (2010). These findings confirm the previously reported association between World Trade Center dust exposure and bronchiolar and interstitial lung disease. Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Workers United States lung Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Details Bronchiolitis | Fibrosis | Metaplasia | Pneumonia
50. Stamp LK, et al. (2015). We have replicated findings identifying dust exposure (grain and silica) and farm exposure as risk factors for granulomatosis with polyangiitis; we have shown activities associated with exposure to inhaled antigens (in particular those related to farming or gardening) may increase the risk of the disease. Antigens | Dust | Silicon Dioxide Controls for disease:Granulomatosis with Polyangiitis | Subjects with disease:Granulomatosis with Polyangiitis New Zealand Details Granulomatosis with Polyangiitis
1–50 of 183 results.