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Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities

These phenotypes are associated with Congenital, Hereditary, and Neonatal Diseases and Abnormalities or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 243,896 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. cell proliferation Abnormalities, Drug-Induced Inferred via 118 chemicals: 1,10-phenanthroline | 1,4-anthraquinone | 3,4,5,3',4'-pentachlorobiphenyl | 3,5,6-trichloro-2-pyridinol | 4,4'-hexafluorisopropylidene diphenol | 4-aminophenol | Acetaminophen | Amitriptyline | Amphetamine | Anthraquinones | Arachidonic Acid | arsenic acid | Aspirin | Azacitidine | Benzene | bisphenol A | boric acid | Busulfan | Butylated Hydroxytoluene | butylparaben | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Calcium | Cannabidiol | Capsaicin | Chlordecone | Chloroquine | Cisplatin | Cladribine | Cocaine | Colchicine | cyanoginosin LR | cyclopamine | Cyclophosphamide | Cytarabine | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Diethylstilbestrol | Dihydrotestosterone | Disulfiram | Doxorubicin | Ellagic Acid | Enalapril | Estradiol | Ethanol | Ethinyl Estradiol | Folic Acid | Freund's Adjuvant | Genistein | Halothane | Herbicides | Hydroxyurea | Ibuprofen | Isotretinoin | Ketoconazole | mancozeb | Maneb | manganese chloride | Methamphetamine | Methimazole | Methotrexate | Methoxychlor | methylmercuric chloride | Methylmercury Compounds | Methylnitrosourea | metolachlor | Mibefradil | Morphine | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | naphthalene | neocuproine | Nicotine | Nifedipine | nitrofen | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | Ouabain | Oxamic Acid | Oxygen | Parathion | Paroxetine | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Piperonyl Butoxide | Plant Preparations | propiconazole | propylparaben | pyrazolanthrone | pyrene | Quercetin | Raloxifene Hydrochloride | Reactive Oxygen Species | retinol palmitate | Roxarsone | Smoke | Sodium Salicylate | Sulfasalazine | Tetrachlorodibenzodioxin | Thalidomide | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | trichostatin A | Triclosan | Triiodothyronine | Urethane | Valproic Acid | Verapamil | vinclozolin | Vitamin A | Warfarin | XAV939   1122
2. apoptotic process Abnormalities, Drug-Induced Inferred via 102 chemicals: 1,10-phenanthroline | 2,3-dimethoxy-1,4-naphthoquinone | 6-formylindolo(3,2-b)carbazole | Acetaminophen | Acetazolamide | Amitriptyline | Amphetamine | Arachidonic Acid | Aspirin | Azacitidine | bisphenol A | Butylated Hydroxytoluene | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Calcium | Capsaicin | Cefotaxime | Chlorambucil | Chloroquine | Cisplatin | Cladribine | Clomipramine | Cocaine | Colchicine | cyanoginosin LR | cyclopamine | Cyclophosphamide | Cytarabine | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Diethylstilbestrol | Dihydrotestosterone | Disulfiram | Doxorubicin | Ellagic Acid | Enalapril | Estradiol | Ethanol | Ethinyl Estradiol | Folic Acid | Genistein | Haloperidol | Halothane | Hydroxyurea | Ibuprofen | Isotretinoin | kenpaullone | Ketoconazole | Maneb | manganese chloride | Methadone | Methamphetamine | Methimazole | Methotrexate | methoxyacetic acid | methylmercuric chloride | Methylmercury Compounds | Methylnitrosourea | Morphine | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | neocuproine | Nicotine | Nifedipine | nitrofen | Ouabain | Oxygen | Paroxetine | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Piroxicam | Plant Preparations | pyrazolanthrone | Quercetin | Raloxifene Hydrochloride | Reactive Oxygen Species | retinol palmitate | SCH 23390 | Selenium | Smoke | Sodium Salicylate | Sulfasalazine | Terbutaline | Tetrachlorodibenzodioxin | Thalidomide | Tobacco Smoke Pollution | Tretinoin | trichostatin A | Triclosan | Triiodothyronine | Valproic Acid | Verapamil | vinclozolin | Vitamin A | Warfarin | Zidovudine   1403
3. cell death Abnormalities, Drug-Induced Inferred via 90 chemicals: 3',5'-dimethylacetaminophen | 4-aminophenol | Acetaminophen | Amitriptyline | Arachidonic Acid | arsenic acid | Aspirin | Azacitidine | bisphenol A | Bupropion | Busulfan | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Calcium | Capsaicin | Carbamazepine | Chlorambucil | Chloroquine | Cisplatin | Cladribine | Cocaine | Colchicine | cyclopamine | Cytarabine | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Disulfiram | Doxorubicin | Dronabinol | Ellagic Acid | Enalapril | Endocrine Disruptors | epoxiconazole | Estradiol | Ethanol | Ethinyl Estradiol | Genistein | Haloperidol | Hydroxyurea | Ibuprofen | Ketoconazole | mancozeb | Maneb | manganese chloride | Methadone | Methamphetamine | Methimazole | Methotrexate | Methoxychlor | methylmercuric chloride | Methylmercury Compounds | Mibefradil | Misoprostol | Morphine | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | naphthalene | Nicotine | Nifedipine | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | Ouabain | Oxygen | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Piroxicam | pyrazolanthrone | Quercetin | Quinine | Raloxifene Hydrochloride | Reactive Oxygen Species | Selenium | Smoke | Tetrachlorodibenzodioxin | Thalidomide | Tobacco Smoke Pollution | Tretinoin | Triamcinolone Acetonide | Trichloroethylene | trichostatin A | Triclosan | Trinitrotoluene | Valproic Acid | Verapamil | Vitamin A | Warfarin | Zidovudine   560
4. positive regulation of cell death Abnormalities, Drug-Induced Inferred via 86 chemicals: 1,10-phenanthroline | 4-aminophenol | 6-formylindolo(3,2-b)carbazole | abamectin | Acetaminophen | Amitriptyline | Arachidonic Acid | arsenic acid | Aspirin | Azacitidine | benz(a)anthracene | Benzene | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | Cannabidiol | Carbamazepine | Chlorambucil | Chloroquine | Cisplatin | Cladribine | Colchicine | Cyclophosphamide | Cytarabine | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | dicrotophos | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Dronabinol | Estradiol | Ethanol | Ethinyl Estradiol | Folic Acid | Freund's Adjuvant | Genistein | Herbicides | Hydroxyurea | Ibuprofen | Isotretinoin | Ketoconazole | mancozeb | Maneb | manganese chloride | Methamphetamine | Methanol | Methotrexate | methoxyacetic acid | methylmercuric chloride | Methylmercury Compounds | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | naphthalene | Nicotine | Nifedipine | O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate | Ouabain | Oxygen | Parathion | Paroxetine | Pentachlorophenol | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Piperonyl Butoxide | Piroxicam | Plant Preparations | pyrazolanthrone | Quercetin | Raloxifene Hydrochloride | Reactive Oxygen Species | Smoke | Sodium Salicylate | Tetrachlorodibenzodioxin | Thalidomide | Tobacco Smoke Pollution | Tretinoin | Triamcinolone Acetonide | trichostatin A | Triclosan | Valproic Acid | Verapamil   449
5. cell proliferation Fetal Growth Retardation Inferred via 79 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulfonyl)phenyl-2(5H)-furanone | 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Alcohols | Amiodarone | Arsenic | Aspirin | Atrazine | Azacitidine | Benzo(a)pyrene | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | bisphenol A | Busulfan | Cadmium | Cadmium Chloride | cadmium oxide | Caffeine | candesartan | Chlormequat | Chloroquine | Cocaine | DDT | decabromobiphenyl ether | Decitabine | Dexamethasone | diallyl trisulfide | Diethylhexyl Phthalate | diethyl phthalate | Diquat | Emodin | Enalapril | Ethanol | fenvalerate | Fluorouracil | Folic Acid | fumonisin B1 | ginsenoside Rg1 | Glucose | Hexachlorobenzene | Homocysteine | Ibuprofen | Indomethacin | Ketoconazole | Lead | lead acetate | Lipopolysaccharides | Manganese | Melatonin | Mercaptopurine | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | nitrofen | Oxygen | Particulate Matter | perfluorooctanoic acid | Phenobarbital | Phenytoin | Polychlorinated Biphenyls | Polycyclic Aromatic Hydrocarbons | Propylthiouracil | prothioconazole | pyrazolanthrone | Resveratrol | sanguinarine | Smoke | T-2 Toxin | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Triclosan | Tunicamycin | Valproic Acid | Vitamin E | Warfarin Inferred via 1 gene: ORC1 1012
6. apoptotic process Fetal Growth Retardation Inferred via 76 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | Acetylcysteine | Amiodarone | Angiotensin-Converting Enzyme Inhibitors | Arsenic | Aspirin | Atrazine | Azacitidine | Benzo(a)pyrene | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | Betamethasone | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | candesartan | Chloroquine | Cocaine | DDT | decabromobiphenyl ether | Decitabine | Dexamethasone | diallyl trisulfide | Diethylhexyl Phthalate | Diquat | Emodin | Enalapril | Ethanol | Fluorouracil | Folic Acid | fumonisin B1 | Glucose | Hexachlorobenzene | Hexachlorocyclohexane | Homocysteine | Ibuprofen | Indomethacin | Ketoconazole | Lead | lead acetate | Lipopolysaccharides | Magnesium Sulfate | Malondialdehyde | Manganese | Melatonin | Mercaptopurine | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | nitrofen | Nitrogen Dioxide | Oxygen | Particulate Matter | Pentazocine | perfluorooctanoic acid | Phenobarbital | Phenytoin | Piroxicam | Polychlorinated Biphenyls | Propylthiouracil | pyrazolanthrone | Resveratrol | sanguinarine | Smoke | T-2 Toxin | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Triclosan | Tunicamycin | Valproic Acid | Vitamin E | Warfarin   1325
7. apoptotic process Long QT Syndrome Inferred via 74 chemicals: Acetaminophen | Albuterol | Amiodarone | Amitriptyline | Arsenic Trioxide | Astemizole | Atenolol | Atropine | Azithromycin | belinostat | Caffeine | Chloroquine | Chlorpromazine | Ciprofloxacin | Citalopram | Clarithromycin | Clomipramine | Clozapine | Cocaine | Daunorubicin | Desipramine | Dexmedetomidine | Diatrizoate | Digoxin | Diltiazem | Diphenhydramine | Dobutamine | Donepezil | Dopamine | Doxorubicin | Epinephrine | Epirubicin | Ethanol | ezogabine | Fingolimod Hydrochloride | Fluoxetine | Glyburide | Haloperidol | Hydrocortisone | Hydroxychloroquine | Idarubicin | Imatinib Mesylate | Imipramine | Indapamide | Iohexol | Irbesartan | Isoproterenol | Ketoconazole | LAQ824 | Lidocaine | Magnesium Sulfate | Maprotiline | Methadone | Metoprolol | Milrinone | Mitoxantrone | Nicotine | Nifedipine | Nortriptyline | Ofloxacin | Olanzapine | Papaverine | Paroxetine | Phenytoin | Pimozide | Potassium | Propranolol | Quetiapine Fumarate | Quinidine | romidepsin | Simvastatin | Terfenadine | Thioctic Acid | Valsartan Inferred via 1 gene: PTEN 846
8. regulation of heart rate Long QT Syndrome Inferred via 72 chemicals: Acetaminophen | Adrenergic beta-Antagonists | Ajmaline | Albuterol | Amiodarone | Amitriptyline | Atenolol | Atropine | bedaquiline | Bepridil | Bisoprolol | Caffeine | Cisapride | Clomipramine | Clozapine | Cocaine | Desflurane | Desipramine | Dexmedetomidine | Digitalis Glycosides | Digoxin | Diltiazem | Diphenhydramine | Disopyramide | Dobutamine | dofetilide | Domperidone | Donepezil | Dopamine | Doxorubicin | Enalaprilat | Epinephrine | Ethanol | Fentanyl | Fingolimod Hydrochloride | Flecainide | Fluoxetine | Haloperidol | Hydrocortisone | ibutilide | Imipramine | Indapamide | Isoproterenol | Lidocaine | Lorazepam | Magnesium Sulfate | Maprotiline | Metoprolol | Mexiletine | Mianserin | Milrinone | Moclobemide | Neostigmine | Nicotine | Nifedipine | Nortriptyline | Ofloxacin | Papaverine | Paroxetine | Pentamidine | Prenylamine | Propranolol | Quinidine | R 56865 | sertindole | Simvastatin | Sotalol | sparfloxacin | Terfenadine | Timolol | Trazodone | Triazolam Inferred via 1 gene: SCN5A 821
9. cell proliferation Neural Tube Defects Inferred via 70 chemicals: 2-Acetylaminofluorene | 2-oxothiazolidine-4-carboxylic acid | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Alcohols | alpha-Tocopherol | Amitriptyline | antimycin | Arachidonic Acid | Arsenic | arsenic acid | Arsenic Trioxide | Azacitidine | Benomyl | Benzene | Benzo(a)pyrene | Betaine | Bromodeoxyuridine | Cadmium | Cadmium Chloride | Caffeine | Chloroquine | Cholecalciferol | Cocaine | Colchicine | Cyclophosphamide | Cyproterone Acetate | Diethylhexyl Phthalate | Ethanol | Fingolimod Hydrochloride | Fluorouracil | Folic Acid | Freund's Adjuvant | fumonisin B1 | Glucose | Heparin | Homocysteine | Hydroxyurea | Isoflavones | Leflunomide | Lidocaine | Lipopolysaccharides | Lithium | mancozeb | Methotrexate | mono-(2-ethylhexyl)phthalate | Morphine | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | Nicotine | Nitric Oxide | Nitroprusside | ochratoxin A | Paraoxon | Phenobarbital | Phenytoin | Piperonyl Butoxide | Quercetin | Resveratrol | Smoke | sodium arsenate | sodium arsenite | Streptozocin | Thymidine | Tretinoin | Valproic Acid | Vitamin A | Vitamin E | Zinc Inferred via 3 genes: PAX3 | PYY | SKI 981
10. regulation of blood pressure Long QT Syndrome Inferred via 70 chemicals: Acetaminophen | Adrenergic beta-Antagonists | Albuterol | Amantadine | Amitriptyline | Antidepressive Agents, Tricyclic | Atenolol | Atropine | Bepridil | Bisoprolol | Caffeine | Chloroquine | Chlorpromazine | Cisapride | Clomipramine | Cocaine | Desflurane | Desipramine | Dexmedetomidine | Digitalis Glycosides | Digoxin | Diltiazem | Dimercaprol | Diphenhydramine | Disopyramide | Dobutamine | Domperidone | Dopamine | Doxapram | Droperidol | Enalaprilat | Epinephrine | Ethanol | Fentanyl | Flecainide | Fluoxetine | Glyburide | Haloperidol | Hydrocortisone | Imipramine | Indapamide | Irbesartan | Isoproterenol | Lidocaine | Magnesium | Magnesium Sulfate | Maprotiline | Meperidine | Mesoridazine | Methadone | Metoprolol | Mexiletine | Mianserin | Milrinone | Neostigmine | Nicotine | Nifedipine | Nortriptyline | Ondansetron | Papaverine | Pentamidine | Potassium | Propranolol | Quinidine | Simvastatin | Sotalol | Thioctic Acid | Timolol | Trazodone | Valsartan Inferred via 1 gene: POMC 877
11. cell death Fetal Growth Retardation Inferred via 69 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acrylamide | Amiodarone | Aspirin | Azacitidine | Benzo(a)pyrene | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | bisphenol A | Busulfan | Cadmium | Cadmium Chloride | Caffeine | Carbamazepine | Chloroquine | Cocaine | decabromobiphenyl ether | Decitabine | Dexamethasone | diallyl trisulfide | Diquat | Enalapril | Ethanol | fenvalerate | Fluorouracil | fumonisin B1 | ginsenoside Rg1 | Glucose | Hexachlorobenzene | Hexachlorocyclohexane | Homocysteine | Ibuprofen | Indomethacin | Ketoconazole | Lead | lead acetate | Lipopolysaccharides | Manganese | Melatonin | Mercaptopurine | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | Nitrogen Dioxide | Oxygen | Particulate Matter | perfluorooctanoic acid | Phenobarbital | Phenytoin | Piroxicam | Polycyclic Aromatic Hydrocarbons | pyrazolanthrone | Resveratrol | sanguinarine | Smoke | T-2 Toxin | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tolmetin | Tretinoin | Triclosan | Tunicamycin | Valproic Acid | Vitamin E | Warfarin   472
12. cell death Long QT Syndrome Inferred via 66 chemicals: Acetaminophen | Albuterol | Amantadine | Amiodarone | Amitriptyline | Amphotericin B | Arsenic Trioxide | Atropine | Azathioprine | belinostat | Bepridil | Caffeine | Carbamazepine | Ceftriaxone | Chloroquine | Chlorpromazine | cifenline | Clozapine | Cocaine | Daunorubicin | Desflurane | Desipramine | Digoxin | Diltiazem | Dopamine | Doxorubicin | Dronedarone | Epirubicin | Ethanol | Eugenol | Fingolimod Hydrochloride | Fluoxetine | Glyburide | halofantrine | Haloperidol | Idarubicin | Imatinib Mesylate | Imipramine | Indapamide | Isoproterenol | Itraconazole | Ketoconazole | Lidocaine | Magnesium | Maprotiline | Methadone | Metoprolol | Mitoxantrone | nefazodone | Nicotine | Nifedipine | Nortriptyline | Ofloxacin | Papaverine | pazopanib | Pentamidine | Phenytoin | Primaquine | Probucol | Propranolol | Quinidine | Quinine | Simvastatin | Sunitinib | Thioctic Acid | Timolol   414
13. response to oxidative stress Abnormalities, Drug-Induced Inferred via 63 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | 4-aminophenol | 7-aminocephalosporanic acid | Acetaminophen | Amitriptyline | Arachidonic Acid | Aspirin | bisphenol A | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | Caffeine | Calcium | Capsaicin | Cefepime | Chloroquine | Cisplatin | Cladribine | Clomipramine | Cocaine | Colchicine | Cyclophosphamide | Daunorubicin | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Disulfiram | Doxorubicin | Enalapril | Endrin | Estradiol | Ethanol | Genistein | Haloperidol | Halothane | Isotretinoin | manganese chloride | Methamphetamine | Methimazole | methylmercuric chloride | Methylmercury Compounds | Misoprostol | Morphine | Nicotine | Nifedipine | nitrofen | Nitrofurantoin | Ouabain | Oxygen | Phenobarbital | Plant Preparations | Quercetin | Reactive Oxygen Species | Selenium | Smoke | Sulfasalazine | Tetrachlorodibenzodioxin | Thalidomide | Thiram | Tobacco Smoke Pollution | Tretinoin | trichostatin A | Valproic Acid | Vitamin A Inferred via 1 gene: CAT 363
14. cell proliferation Long QT Syndrome Inferred via 62 chemicals: Acetaminophen | Albuterol | Amiodarone | Amitriptyline | Amphotericin B | Arsenic Trioxide | Astemizole | Atenolol | Atropine | Azithromycin | Caffeine | Chloroquine | Chlorpromazine | Ciprofloxacin | Citalopram | Clozapine | Cocaine | Daunorubicin | Desflurane | Desipramine | Diatrizoate | Diltiazem | Diphenhydramine | Donepezil | Dopamine | Doxorubicin | Epinephrine | Ethanol | Eugenol | Fingolimod Hydrochloride | Fluoxetine | Hydrocortisone | Hydroxychloroquine | Idarubicin | Imatinib Mesylate | Imipramine | Indapamide | Isoproterenol | Itraconazole | Ketoconazole | LAQ824 | Lidocaine | Maprotiline | Milrinone | Mitoxantrone | N-(1-(2,3-dimethoxyphenyl)-4-methyl-3-penten-1-yl)-1-(5-bromofurfuryl)-1-piperidyl-4-amine | nefazodone | Nicotine | Nifedipine | Ofloxacin | Olanzapine | Papaverine | Paroxetine | Phenytoin | Pimozide | Propranolol | Quinidine | SB939 compound | Simvastatin | Sunitinib | Terfenadine | Thioctic Acid Inferred via 2 genes: CYP1A1 | PTEN 555
15. apoptotic process Neural Tube Defects Inferred via 61 chemicals: 2-Acetylaminofluorene | Acetaminophen | Acetylcysteine | Air Pollutants | alpha-Tocopherol | Amitriptyline | antimycin | Arachidonic Acid | Arsenic | Arsenic Trioxide | Azacitidine | Benzo(a)pyrene | Betaine | Cadmium | Cadmium Chloride | Caffeine | Chlorambucil | Chloroquine | Cholecalciferol | Cocaine | Colchicine | Cyclophosphamide | Diethylhexyl Phthalate | Ethanol | Fingolimod Hydrochloride | Fluorouracil | Folic Acid | fumonisin B1 | Glucose | Haloperidol | Heparin | Homocysteine | Hydroxyurea | Isoflavones | Leflunomide | Leucovorin | Lidocaine | Lipopolysaccharides | Lithium | Methotrexate | mono-(2-ethylhexyl)phthalate | Morphine | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | Nicotine | Nitric Oxide | Nitroprusside | ochratoxin A | Phenobarbital | Phenytoin | Quercetin | Resveratrol | Smoke | sodium arsenite | Streptozocin | Thymidine | Tretinoin | Valproic Acid | Vitamin A | Vitamin E | Zinc Inferred via 2 genes: IFNG | PAX3 1299
16. regulation of mitochondrial membrane potential Abnormalities, Drug-Induced Inferred via 60 chemicals: 6-formylindolo(3,2-b)carbazole | Acetaminophen | Amitriptyline | Amphetamine | Arachidonic Acid | Aspirin | bisphenol A | Bupropion | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Calcium | Capsaicin | Chlorambucil | Cisplatin | Cladribine | Cocaine | cyanoginosin LR | Daunorubicin | Dexamethasone | Diethylhexyl Phthalate | Dihydrotestosterone | Disulfiram | Doxorubicin | Ellagic Acid | Estradiol | Ethanol | Haloperidol | Lithium Carbonate | manganese chloride | Methamphetamine | methoxyacetic acid | Methylmercury Compounds | Misoprostol | Morphine | neocuproine | Nicotine | Nifedipine | nitrofen | Ouabain | Oxygen | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Plant Preparations | pyrazolanthrone | Quercetin | Reactive Oxygen Species | Selenium | Sulfasalazine | Terbutaline | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Triclosan | Valproic Acid | Verapamil | Vitamin A | Zidovudine   322
17. positive regulation of cell death Fetal Growth Retardation Inferred via 59 chemicals: Acetylcysteine | Acrylamide | Amiodarone | Arsenic | Aspirin | Atrazine | Azacitidine | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | Carbamazepine | Chloroquine | Decitabine | Dexamethasone | Diethylhexyl Phthalate | Diquat | Emodin | Ethanol | Fluorouracil | Folic Acid | fumonisin B1 | ginsenoside Rg1 | Glucose | Ibuprofen | Indomethacin | Ketoconazole | Lead | lead acetate | Lipopolysaccharides | Malondialdehyde | Manganese | Melatonin | Mercaptopurine | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | Oxygen | Particulate Matter | perfluorooctanoic acid | Phenobarbital | Phenytoin | Piroxicam | Polychlorinated Biphenyls | Polycyclic Aromatic Hydrocarbons | Propylthiouracil | pyrazolanthrone | Resveratrol | Smoke | Tetrachlorodibenzodioxin | Thallium | Tobacco Smoke Pollution | Tretinoin | Triclosan | Tunicamycin | Valproic Acid   327
18. apoptotic DNA fragmentation Abnormalities, Drug-Induced Inferred via 57 chemicals: 1,2-naphthoquinone | 1,4-anthraquinone | Acetaminophen | Amitriptyline | Arachidonic Acid | Aspirin | Azacitidine | Cadmium | Cadmium Chloride | Caffeine | Calcium | Cannabidiol | Capsaicin | Chloroquine | Cisplatin | Cladribine | Clomipramine | Cocaine | Colchicine | cyanoginosin LR | Cyclophosphamide | Cytarabine | Daunorubicin | Dexamethasone | Disulfiram | Doxorubicin | Enalapril | Estradiol | Ethanol | Genistein | Haloperidol | Halothane | Hydroxyurea | Ibuprofen | Isotretinoin | Methadone | methylmercuric chloride | Morphine | neocuproine | Nicotine | Nifedipine | Ouabain | Oxygen | Phenobarbital | pyrazolanthrone | Quercetin | Reactive Oxygen Species | Smoke | Sodium Salicylate | Sulfasalazine | Terbutaline | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | Valproic Acid | Verapamil | Vitamin A   341
19. cell death Neural Tube Defects Inferred via 57 chemicals: 2-oxothiazolidine-4-carboxylic acid | 3',5'-dimethylacetaminophen | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | alpha-Tocopherol | Amitriptyline | antimycin | Arachidonic Acid | arsenic acid | Arsenic Trioxide | Azacitidine | Benzo(a)pyrene | Cadmium | Cadmium Chloride | Caffeine | Carbamazepine | Chlorambucil | Chloroquine | Cocaine | Colchicine | Dronabinol | Ethanol | Fingolimod Hydrochloride | Fluorouracil | fumonisin B1 | Glucose | Haloperidol | Heparin | Homocysteine | Hydroxyurea | Leflunomide | Lidocaine | Lipopolysaccharides | Lithium | mancozeb | Methotrexate | Morphine | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | Nicotine | Nitric Oxide | Nitroprusside | ochratoxin A | Phenobarbital | Phenytoin | Quercetin | Resveratrol | Smoke | sodium arsenate | sodium arsenite | Streptozocin | Tretinoin | Valproic Acid | Vitamin A | Vitamin E | Zinc   462
20. positive regulation of apoptotic process Abnormalities, Drug-Induced Inferred via 56 chemicals: 6-formylindolo(3,2-b)carbazole | Acetaminophen | Aspirin | bisphenol A | butylparaben | Cadmium | Cadmium Chloride | Cannabidiol | Carbamazepine | Chlorambucil | Chloroquine | Cisplatin | cyanoginosin LR | Cyclophosphamide | Cytarabine | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Ellagic Acid | Estradiol | Ethanol | Genistein | Herbicides | Ibuprofen | Ketoconazole | mancozeb | manganese chloride | Methamphetamine | Methotrexate | methoxyacetic acid | methylmercuric chloride | Methylmercury Compounds | Nicotine | nitrofen | Oxygen | Parathion | perfluorooctane sulfonic acid | Plant Preparations | pyrazolanthrone | Quercetin | Quinine | quinone | Reactive Oxygen Species | tebuconazole | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | trichostatin A | Valproic Acid | Verapamil | Warfarin | Ziram Inferred via 1 gene: WNT11 389
21. cell proliferation Congenital Abnormalities Inferred via 55 chemicals: 2,4-decadienal | 2-oxothiazolidine-4-carboxylic acid | Aflatoxin B1 | Alitretinoin | alpha-naphthoflavone | Benzo(a)pyrene | beta-Naphthoflavone | bisphenol A | Cadmium | Cadmium Chloride | cadmium sulfate | Copper | Cyclophosphamide | cypermethrin | daidzein | DDT | Dichlorodiphenyldichloroethane | Diethylhexyl Phthalate | Epinephrine | Ethanol | fenvalerate | Folic Acid | Genistein | Glucose | Griseofulvin | Herbicides | Ifosfamide | imidacloprid | Lead | Lipopolysaccharides | Mechlorethamine | Mercaptopurine | Mercuric Chloride | Methylmercury Compounds | Oxygen | Particulate Matter | perfluorooctane sulfonic acid | phenanthrene | Phenytoin | Phytoestrogens | Propylthiouracil | pyrene | Pyrimethamine | Ribavirin | Simazine | Tetrachlorodibenzodioxin | titanium dioxide | Tretinoin | tributyl phosphate | Triclosan | tris(1,3-dichloro-2-propyl)phosphate | Tritolyl Phosphates | Valproic Acid | Vincristine | Vitamin E Inferred via 1 gene: SIX1 504
22. membrane lipid catabolic process Abnormalities, Drug-Induced Inferred via 55 chemicals: 1,10-phenanthroline | 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Amitriptyline | Anthraquinones | Arachidonic Acid | Aspirin | Benzene | bisphenol A | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | Calcium | Capsaicin | Cisplatin | Clomipramine | Cocaine | Colchicine | Cyclophosphamide | Daunorubicin | Dexamethasone | Diethylhexyl Phthalate | Diethylstilbestrol | Disulfiram | Doxorubicin | Enalapril | Endrin | Estradiol | Ethanol | Haloperidol | Halothane | Herbicides | Ibuprofen | Isotretinoin | Ketoconazole | Lithium Carbonate | methylmercuric chloride | Methylmercury Compounds | Nicotine | Nifedipine | Oxygen | Phenobarbital | Piperonyl Butoxide | Plant Preparations | Quercetin | Reactive Oxygen Species | retinol palmitate | Selenium | Smoke | Sodium Salicylate | Tetrachlorodibenzodioxin | Thalidomide | Tobacco Smoke Pollution | Tretinoin | Vitamin A   289
23. cell proliferation Heart Defects, Congenital Inferred via 54 chemicals: 3,4,3',4'-tetrachlorobiphenyl | 3,4,5,3',4'-pentachlorobiphenyl | Acitretin | Albendazole | Alitretinoin | Alprostadil | Arachidonic Acid | arsenic acid | Ascorbic Acid | Benzo(a)pyrene | bisphenol A | Cadmium Chloride | Caffeine | Carvedilol | Cocaine | Copper | Cyproterone Acetate | Diethylstilbestrol | Doxorubicin | Estradiol | Estrogens | Ethanol | Folic Acid | Formaldehyde | Homocysteine | Indomethacin | Isotretinoin | Lithium | Lithium Chloride | Lovastatin | Mycophenolic Acid | Niacinamide | nitrofen | nonylphenol | Paroxetine | Phenobarbital | Phenytoin | Progesterone | pyrene | Streptozocin | Sulfasalazine | Tetrachlorodibenzodioxin | Thalidomide | Theophylline | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | Triiodothyronine | Valproic Acid | Vitamin A | Vitamin E | Warfarin | XAV939 | Zinc Inferred via 4 genes: EDNRA | TBX1 | TGFB2 | VEGFA 613
24. cell proliferation Craniofacial Abnormalities Inferred via 53 chemicals: 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide | 3,4,5,3',4'-pentachlorobiphenyl | 6-methyl-2-(phenylethynyl)pyridine | Acitretin | Arachidonic Acid | Arsenic Trioxide | Benzene | Benzophenanthridines | bisphenol A | bisphenol F | Chlorpyrifos | cyclopamine | decamethrin | Dexamethasone | Dichloroacetic Acid | Disulfiram | Estradiol | Ethanol | ethyl tert-butyl ether | Fluorouracil | Glucocorticoids | glyphosate | Hydrocortisone | Imatinib Mesylate | Isotretinoin | Ketamine | Lead | lead acetate | Leflunomide | Methimazole | Methotrexate | Nitric Oxide | nitrofen | Nitroprusside | ochratoxin A | Permethrin | phenanthrene | Phenobarbital | Phenytoin | Plant Extracts | Polycyclic Aromatic Hydrocarbons | pyrene | Reactive Oxygen Species | sodium arsenate | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | Valproic Acid | Vitamin A | Vitamin E | Warfarin | XAV939 | Zinc Inferred via 14 genes: CTNNB1 | DLX5 | EDNRA | EGFR | FOXC2 | LRP2 | PAX3 | PTEN | SIX1 | SKI | SMAD4 | TBX1 | TGFB2 | TP63 695
25. positive regulation of cell death Neural Tube Defects Inferred via 53 chemicals: Acetaminophen | Acetylcysteine | alpha-Tocopherol | Amitriptyline | Arachidonic Acid | Arsenic | arsenic acid | Arsenic Trioxide | Azacitidine | Benomyl | Benzene | Bromodeoxyuridine | Cadmium | Cadmium Chloride | Caffeine | Carbamazepine | Chlorambucil | Chloroquine | Cholecalciferol | Colchicine | Cyclophosphamide | Cytochalasin D | Diethylhexyl Phthalate | Dronabinol | Ethanol | Fluorouracil | Folic Acid | Freund's Adjuvant | fumonisin B1 | Glucose | Hydroxyurea | Leflunomide | Lipopolysaccharides | mancozeb | Methotrexate | mono-(2-ethylhexyl)phthalate | Mycophenolic Acid | N-acetyl-4-benzoquinoneimine | Nicotine | Nitric Oxide | ochratoxin A | Paraoxon | Phenobarbital | Phenytoin | Piperonyl Butoxide | Quercetin | Resveratrol | Smoke | sodium arsenite | Streptozocin | Tretinoin | Valproic Acid | Zinc   345
26. positive regulation of cell proliferation Abnormalities, Drug-Induced Inferred via 53 chemicals: 4,4'-hexafluorisopropylidene diphenol | 6-formylindolo(3,2-b)carbazole | Aspirin | bisphenol A | boric acid | butylparaben | Cadmium Chloride | Calcium | Capsaicin | Chloroquine | Cisplatin | cyanoginosin LR | Cytarabine | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Diethylstilbestrol | Dihydrotestosterone | Disulfiram | Doxorubicin | Estradiol | Ethanol | Ethinyl Estradiol | Fluconazole | Folic Acid | Genistein | Ketoconazole | Methotrexate | Methoxychlor | monobutyl phthalate | Mycophenolic Acid | Nicotine | Oxygen | Paroxetine | Phenobarbital | Plant Preparations | pyrazolanthrone | Quercetin | Reactive Oxygen Species | Roxarsone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | trichostatin A | Triclosan | Triiodothyronine | triphenyltin hydroxide | Valproic Acid | vinclozolin | Warfarin   287
27. positive regulation of apoptotic process Fetal Growth Retardation Inferred via 52 chemicals: 8-oxo-7-hydrodeoxyguanosine | Acetylcysteine | Acrylamide | Amiodarone | Arsenic | Aspirin | Atrazine | Benzo(a)pyrene | benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | bisphenol A | Cadmium | Cadmium Chloride | Carbamazepine | Chloroquine | Decitabine | Dexamethasone | diallyl trisulfide | Diethylhexyl Phthalate | Emodin | Ethanol | Fluorouracil | fumonisin B1 | ginsenoside Rg1 | Glucose | Ibuprofen | Indomethacin | Ketoconazole | Lead | lead acetate | Lipopolysaccharides | Manganese | Melatonin | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | nitrofen | Oxygen | Particulate Matter | perfluorooctanoic acid | pyrazolanthrone | Resveratrol | sanguinarine | T-2 Toxin | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Tunicamycin | Valproic Acid | Vitamin E | Warfarin Inferred via 3 genes: MMP2 | NOS3 | SOD1 367
28. positive regulation of reactive oxygen species biosynthetic process Abnormalities, Drug-Induced Inferred via 52 chemicals: 1,10-phenanthroline | 1,2-naphthoquinone | 3,4,5,3',4'-pentachlorobiphenyl | 4,4'-hexafluorisopropylidene diphenol | 6-formylindolo(3,2-b)carbazole | Acetaminophen | Amitriptyline | benz(a)anthracene | Benzene | bisphenol A | Cadmium | Cadmium Chloride | Cannabidiol | Cisplatin | cyanoginosin LR | Dexamethasone | Dichlorodiphenyl Dichloroethylene | dicrotophos | Disulfiram | Doxorubicin | Dronabinol | Ellagic Acid | Enalapril | Estradiol | Ethanol | Genistein | Ibuprofen | Ketoconazole | mancozeb | manganese chloride | Methamphetamine | Methotrexate | methylmercuric chloride | monobutyl phthalate | Oxygen | perfluorooctane sulfonic acid | Plant Preparations | propiconazole | pyrazolanthrone | pyrene | Quercetin | quinone | Reactive Oxygen Species | Sodium Salicylate | Tetrachlorodibenzodioxin | Thiram | Tobacco Smoke Pollution | Tretinoin | Trichloroethylene | trichostatin A | Valproic Acid | Verapamil   236
29. apoptotic process Heart Defects, Congenital Inferred via 51 chemicals: Acitretin | Alitretinoin | Alprostadil | Arachidonic Acid | Ascorbic Acid | Benzo(a)pyrene | bisphenol A | Cadmium Chloride | Caffeine | Carvedilol | Cefotaxime | Clomipramine | Cocaine | Copper | Diethylstilbestrol | domoic acid | Doxorubicin | Estradiol | Estrogens | Ethanol | Folic Acid | Formaldehyde | Homocysteine | Indomethacin | Isotretinoin | Lithium | Lithium Chloride | Lovastatin | Mycophenolic Acid | Naproxen | Niacinamide | nitrofen | nonylphenol | Paroxetine | Phenobarbital | Phenytoin | Progesterone | Streptozocin | Sulfasalazine | Tetrachlorodibenzodioxin | Thalidomide | Theophylline | Ticlopidine | Tobacco Smoke Pollution | Tretinoin | Triiodothyronine | Valproic Acid | Vitamin A | Vitamin E | Warfarin | Zinc Inferred via 3 genes: ABL1 | AHR | ECE1 718
30. lipid catabolic process Fetal Growth Retardation Inferred via 51 chemicals: 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acrylamide | Adrenergic beta-Antagonists | Alcohols | Amiodarone | Arsenic | Aspirin | Atrazine | Benzo(a)pyrene | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | Charcoal | Chloroquine | Cocaine | decabromobiphenyl ether | Dexamethasone | Dietary Sucrose | Diethylhexyl Phthalate | Dimethoate | Diquat | Enalapril | Ethanol | Fluorouracil | fumonisin B1 | Glucose | Hexachlorobenzene | Indomethacin | lead acetate | Lipopolysaccharides | Magnesium Sulfate | Manganese | Melatonin | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | Oxygen | Particulate Matter | perfluorooctanoic acid | Phenobarbital | Propylthiouracil | pyrazolanthrone | Resveratrol | T-2 Toxin | Testosterone | Tobacco Smoke Pollution | Vitamin E | Warfarin   319
31. cell proliferation Abnormalities, Multiple Inferred via 50 chemicals: 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone | 2,2',4,4'-tetrabromodiphenyl ether | Acitretin | alpha-Tocopherol | Arachidonic Acid | Atrazine | bisphenol A | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Chlorpyrifos | Cladribine | Cocaine | Copper | cupric chloride | Cyclophosphamide | Dibutyl Phthalate | Diclofenac | Estradiol | Flame Retardants | glyphosate | hexabromocyclododecane | Imatinib Mesylate | Isotretinoin | Leflunomide | Lithium Chloride | Manganese | Methotrexate | methylmercuric chloride | Methylmercury Compounds | methylparaben | neocuproine | nonylphenol | perfluorooctane sulfonic acid | phenanthrene | Phenobarbital | Phenytoin | Polycyclic Aromatic Hydrocarbons | pyrazolanthrone | pyrene | Ro 41-5253 | Sodium Salicylate | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | trichostatin A | tris(1,3-dichloro-2-propyl)phosphate | Valproic Acid | Vitamin A Inferred via 4 genes: CTNNB1 | GSK3B | PTEN | TP63 524
32. cell cycle Abnormalities, Drug-Induced Inferred via 50 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | 4,4'-hexafluorisopropylidene diphenol | Acetaminophen | Acridines | Aspirin | Azacitidine | bisphenol A | Cadmium | Caffeine | Capsaicin | Chloroquine | Cisplatin | Cladribine | Cocaine | Colchicine | Cyclophosphamide | Cytarabine | Daunorubicin | Dexamethasone | Diethylstilbestrol | Dihydrotestosterone | Doxorubicin | Ellagic Acid | Estradiol | Genistein | Herbicides | Hydroxyurea | Ibuprofen | Isotretinoin | Methimazole | Methotrexate | Morphine | Mycophenolic Acid | Nicotine | Nifedipine | nitrofen | Ouabain | Pesticides | pyrazolanthrone | Quinine | Raloxifene Hydrochloride | Reactive Oxygen Species | Tetrachlorodibenzodioxin | Thalidomide | Tobacco Smoke Pollution | Tretinoin | Triiodothyronine | Valproic Acid | Vitamin A | Zidovudine Inferred via 1 gene: RHOA 297
33. regulation of blood pressure Abnormalities, Drug-Induced Inferred via 49 chemicals: Acetaminophen | Amitriptyline | Amphetamine | Aspirin | Benzodiazepines | Bupropion | Caffeine | Calcium | Capsaicin | Chlordiazepoxide | Chloroquine | Clomipramine | Cocaine | Dexamethasone | Diethylstilbestrol | Dimethadione | Disulfiram | Dronabinol | Enalapril | Ethanol | Ethinyl Estradiol | Folic Acid | Haloperidol | Halothane | Ibuprofen | Methadone | Methimazole | Mibefradil | Misoprostol | Morphine | Mycophenolic Acid | Nicotine | Nifedipine | Ouabain | Oxygen | perfluorooctane sulfonic acid | Phenobarbital | Quercetin | SCH 23390 | Smoke | Sotalol | Terbutaline | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Urethane | Valproic Acid | Verapamil | Warfarin | xanthone   615
34. positive regulation of cell proliferation Fetal Growth Retardation Inferred via 48 chemicals: 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acrylamide | Arsenic | Aspirin | Atrazine | Benzo(a)pyrene | bisphenol A | Cadmium Chloride | Chloroquine | Decitabine | Dexamethasone | diallyl trisulfide | Diethylhexyl Phthalate | Diquat | Emodin | Ethanol | Fluorouracil | Folic Acid | fumonisin B1 | ginsenoside Rg1 | Glucose | Ketoconazole | lead acetate | Lipopolysaccharides | Manganese | Melatonin | Methotrexate | Miconazole | Nicotine | Oxygen | Particulate Matter | perfluorooctanoic acid | Phenobarbital | Polycyclic Aromatic Hydrocarbons | pyrazolanthrone | Resveratrol | sanguinarine | T-2 Toxin | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Triclosan | Tunicamycin | Valproic Acid | Vitamin E | Warfarin Inferred via 3 genes: AGT | IGF1R | IGF2 250
35. response to oxidative stress Fetal Growth Retardation Inferred via 48 chemicals: Acetylcysteine | Alcohols | Amiodarone | Angiotensin-Converting Enzyme Inhibitors | Arsenic | Aspirin | Benzo(a)pyrene | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | candesartan | Chloroquine | Cocaine | DDT | decabromobiphenyl ether | Dexamethasone | Dietary Sucrose | Diquat | Enalapril | Ethanol | Fluorouracil | Glucose | Hexachlorocyclohexane | Homocysteine | Indomethacin | Lead | Lipopolysaccharides | Manganese | Melatonin | Methamphetamine | Methylmercury Compounds | Nicotine | nitrofen | Nitrogen Dioxide | Oxygen | Particulate Matter | Phenobarbital | Propylthiouracil | Resveratrol | Smoke | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tolmetin | Tretinoin | Valproic Acid | Vitamin E Inferred via 2 genes: MMP2 | SOD1 386
36. glutathione biosynthetic process Fetal Growth Retardation Inferred via 48 chemicals: 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acrylamide | Alcohols | Arsenic | Atrazine | Benzo(a)pyrene | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | Charcoal | Chloroquine | DDT | decabromobiphenyl ether | Decitabine | Dexamethasone | Diethylhexyl Phthalate | Dimethoate | Ethanol | Folic Acid | fumonisin B1 | Glucose | Hexachlorobenzene | Hexachlorocyclohexane | Indomethacin | Ketoconazole | Lead | lead acetate | Lipopolysaccharides | Manganese | Melatonin | Methamphetamine | Methotrexate | Methylmercury Compounds | Nicotine | Oxygen | Particulate Matter | Phenobarbital | Phenytoin | Propylthiouracil | Resveratrol | Smoke | T-2 Toxin | Testosterone | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Vitamin E   270
37. apoptotic process Abnormalities, Multiple Inferred via 47 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acitretin | alpha-Tocopherol | Arachidonic Acid | Atrazine | bisphenol A | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Chlorpyrifos | Cladribine | Cocaine | Copper | cupric chloride | Cyclophosphamide | Dibutyl Phthalate | Diclofenac | Estradiol | hexabromocyclododecane | Imatinib Mesylate | Isotretinoin | kenpaullone | Leflunomide | Lithium Chloride | Manganese | Methotrexate | methoxyacetic acid | methylmercuric chloride | Methylmercury Compounds | methylparaben | neocuproine | nonylphenol | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | pyrazolanthrone | Ro 41-5253 | Sodium Salicylate | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | trichostatin A | tris(1,3-dichloro-2-propyl)phosphate | Uridine | Valproic Acid | Vitamin A Inferred via 4 genes: FGFR2 | GPER1 | PTEN | TP63 547
38. lipid catabolic process Abnormalities, Drug-Induced Inferred via 47 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Arachidonic Acid | Aspirin | bisphenol A | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | Caffeine | Calcium | Chloroquine | Cisplatin | Cocaine | cyanoginosin LR | cyclopamine | Cyclophosphamide | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Dihydrotestosterone | Doxorubicin | Ellagic Acid | Enalapril | Ethanol | Ethinyl Estradiol | Freund's Adjuvant | Genistein | Halothane | Lithium Carbonate | manganese chloride | Methamphetamine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | neocuproine | Nicotine | Oxygen | perfluorooctane sulfonic acid | Phenobarbital | Plant Preparations | pyrazolanthrone | Quercetin | Selenium | Sulfasalazine | Tobacco Smoke Pollution | Warfarin   327
39. response to oxidative stress Neural Tube Defects Inferred via 47 chemicals: 2-oxothiazolidine-4-carboxylic acid | Acetaminophen | Acetylcysteine | Air Pollutants | Alcohols | alpha-Tocopherol | Amitriptyline | antimycin | Arachidonic Acid | Arsenic | Arsenic Trioxide | Benzo(a)pyrene | Cadmium | Cadmium Chloride | Caffeine | Chloroquine | Cocaine | Colchicine | Cyclophosphamide | Ethanol | Fluorouracil | Glucose | Haloperidol | Heparin | Homocysteine | Lidocaine | Lipopolysaccharides | Lithium | methylmercury hydroxide | Morphine | Nicotine | Nitric Oxide | Nitroprusside | ochratoxin A | Phenobarbital | Quercetin | Resveratrol | Smoke | sodium arsenate | sodium arsenite | Streptozocin | Thymidine | Tretinoin | Valproic Acid | Vitamin A | Vitamin E | Zinc   422
40. reactive oxygen species biosynthetic process Abnormalities, Drug-Induced Inferred via 46 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | 6-formylindolo(3,2-b)carbazole | Acetaminophen | Arachidonic Acid | arsenic acid | Benzene | bisphenol A | Cadmium | Cadmium Chloride | Chloroquine | Cisplatin | Cocaine | cyanoginosin LR | Dexamethasone | Dibutyl Phthalate | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Disulfiram | Doxorubicin | Ellagic Acid | Estradiol | Ethanol | Ethinyl Estradiol | Genistein | Lithium Carbonate | manganese chloride | methylmercuric chloride | Methylmercury Compounds | neocuproine | Nicotine | Oxygen | perfluorooctane sulfonic acid | Plant Preparations | pyrazolanthrone | Quercetin | quinone | Smoke | Sulfasalazine | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | Trinitrotoluene | Urethane | Valproic Acid | Verapamil | Zidovudine   261
41. positive regulation of cell death Abnormalities, Multiple Inferred via 45 chemicals: 1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone | 2,2',4,4'-tetrabromodiphenyl ether | alpha-Tocopherol | Arachidonic Acid | Atrazine | benz(a)anthracene | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | Carbamazepine | Chlorpyrifos | Cladribine | Copper | cupric chloride | Cyclophosphamide | Dibutyl Phthalate | Diclofenac | Estradiol | Flame Retardants | glyphosate | hexabromocyclododecane | Imatinib Mesylate | Isotretinoin | Leflunomide | Lithium Chloride | Manganese | Methotrexate | methoxyacetic acid | methylmercuric chloride | Methylmercury Compounds | nonylphenol | perfluorooctane sulfonic acid | phenanthrene | Phenobarbital | Phenytoin | Polycyclic Aromatic Hydrocarbons | pyrazolanthrone | Ro 41-5253 | Sodium Salicylate | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | trichostatin A | Valproic Acid   177
42. regulation of mitochondrial membrane potential Fetal Growth Retardation Inferred via 44 chemicals: Acetylcysteine | Amiodarone | Arsenic | Aspirin | Benzo(a)pyrene | benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone | bisphenol A | Cadmium | Cadmium Chloride | Caffeine | Cocaine | Decitabine | Dexamethasone | diallyl trisulfide | Diethylhexyl Phthalate | Emodin | Ethanol | Fluorouracil | fumonisin B1 | ginsenoside Rg1 | Glucose | Indomethacin | lead acetate | Lipopolysaccharides | Manganese | Melatonin | Methamphetamine | Methylmercury Compounds | Nicotine | nitrofen | Oxygen | Particulate Matter | Phenobarbital | Phenytoin | pyrazolanthrone | Resveratrol | T-2 Toxin | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution | Tretinoin | Triclosan | Tunicamycin | Valproic Acid | Vitamin E Inferred via 1 gene: SOD1 250
43. cell death Craniofacial Abnormalities Inferred via 44 chemicals: 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide | 6-methyl-2-(phenylethynyl)pyridine | Arachidonic Acid | Arsenic Trioxide | Benzophenanthridines | bisphenol A | Carbamazepine | Chlorpyrifos | cyclopamine | decamethrin | Dexamethasone | Dextromethorphan | Dichloroacetic Acid | Disulfiram | Estradiol | Ethanol | Fluorouracil | Glucocorticoids | Imatinib Mesylate | Ketamine | Lead | lead acetate | Leflunomide | Methimazole | Methotrexate | Nitric Oxide | Nitroprusside | ochratoxin A | Permethrin | Phenobarbital | Phenytoin | Plant Extracts | Polycyclic Aromatic Hydrocarbons | Reactive Oxygen Species | sodium arsenate | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | Triamcinolone Acetonide | Valproic Acid | Vitamin A | Vitamin E | Warfarin | Zinc Inferred via 1 gene: TGFB2 272
44. apoptotic process Congenital Abnormalities Inferred via 44 chemicals: Aflatoxin B1 | Alitretinoin | alpha-naphthoflavone | Benzo(a)pyrene | beta-Naphthoflavone | Bexarotene | bisphenol A | Cadmium | Cadmium Chloride | Copper | Cyclophosphamide | cypermethrin | daidzein | DDT | Dichlorodiphenyldichloroethane | Diethylhexyl Phthalate | Epinephrine | Ethanol | Folic Acid | Genistein | Glucose | Lead | Lipopolysaccharides | Mechlorethamine | Mercaptopurine | Mercuric Chloride | Methylmercury Compounds | Oxygen | Particulate Matter | perfluorooctane sulfonic acid | phenyl-N-tert-butylnitrone | Phenytoin | Propylthiouracil | Pyrimethamine | Ribavirin | Simazine | Tetrachlorodibenzodioxin | titanium dioxide | Tretinoin | Triclosan | tris(1,3-dichloro-2-propyl)phosphate | Valproic Acid | Vincristine | Vitamin E Inferred via 1 gene: SIX1 503
45. DNA damage response, detection of DNA damage Abnormalities, Drug-Induced Inferred via 44 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | abamectin | Acetaminophen | arsenic acid | bisphenol A | butylparaben | Cadmium | Cadmium Chloride | Cisplatin | Cocaine | Cyclophosphamide | Dexamethasone | Dibutyl Phthalate | Diethylhexyl Phthalate | Diethylstilbestrol | Doxorubicin | Ellagic Acid | Estradiol | Ethanol | Hydroxyurea | mancozeb | Maneb | manganese chloride | Methylmercury Compounds | Methylnitrosourea | metolachlor | neocuproine | Nicotine | Oxygen | Pentachlorophenol | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | propylparaben | Quercetin | quinone | Selenium | Thalidomide | Thiram | Triclosan | triphenyltin hydroxide | Urethane | Valproic Acid | Zidovudine   234
46. superoxide dismutase activity Fetal Growth Retardation Inferred via 43 chemicals: 2,4,5,2',4',5'-hexachlorobiphenyl | 2,4-Dichlorophenoxyacetic Acid | 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acrylamide | Amiodarone | Arsenic | Atrazine | Benzo(a)pyrene | bisphenol A | Cadmium | Cadmium Chloride | Chloroquine | Cocaine | DDT | decabromobiphenyl ether | Dexamethasone | Diethylhexyl Phthalate | Diquat | Emodin | Ethanol | Fluorouracil | fumonisin B1 | Glucose | Indomethacin | Lead | lead acetate | Lipopolysaccharides | Magnesium Sulfate | Manganese | Melatonin | Methotrexate | Nicotine | Oxygen | Particulate Matter | perfluorooctanoic acid | Phenobarbital | Resveratrol | Smoke | T-2 Toxin | Testosterone | Tobacco Smoke Pollution | Vitamin E Inferred via 1 gene: SOD1 254
47. apoptotic DNA fragmentation Neural Tube Defects Inferred via 43 chemicals: 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | alpha-Tocopherol | Amitriptyline | Arachidonic Acid | Arsenic Trioxide | Azacitidine | Cadmium | Cadmium Chloride | Caffeine | Chloroquine | Cocaine | Colchicine | Cyclophosphamide | Ethanol | Fluorouracil | fumonisin B1 | Glucose | Haloperidol | Heparin | Homocysteine | Hydroxyurea | Lidocaine | Lipopolysaccharides | Lithium | Morphine | Nicotine | Nitric Oxide | Nitroprusside | ochratoxin A | Phenobarbital | Quercetin | Resveratrol | Smoke | sodium arsenite | Streptozocin | Thymidine | Tretinoin | Valproic Acid | Vitamin A | Vitamin E | Zinc Inferred via 1 gene: CECR2 293
48. lipid oxidation Abnormalities, Drug-Induced Inferred via 43 chemicals: 1,10-phenanthroline | 2,3-dimethoxy-1,4-naphthoquinone | 2,4-Dichlorophenoxyacetic Acid | 4,4'-hexafluorisopropylidene diphenol | 4-aminophenol | Acetaminophen | Aspirin | bisphenol A | boric acid | butylparaben | Cadmium Chloride | Calcium | Carbamazepine | Cisplatin | cyanoginosin LR | Cyclophosphamide | Daunorubicin | Dexamethasone | Dibutyl Phthalate | Doxorubicin | Ellagic Acid | Enalapril | Estradiol | Ethanol | Genistein | Ibuprofen | mancozeb | Maneb | manganese chloride | Methamphetamine | Methotrexate | monobutyl phthalate | Oxygen | Pesticides | Piperonyl Butoxide | propiconazole | Quercetin | Reactive Oxygen Species | Selenium | Sulfasalazine | Thalidomide | Tobacco Smoke Pollution | Triclosan   201
49. cell death Abnormalities, Multiple Inferred via 43 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 3,4-dichloroaniline | 6-bromoindirubin-3'-oxime | alpha-Tocopherol | Arachidonic Acid | bisphenol A | Butyrates | Cadmium | Cadmium Chloride | Caffeine | Carbamazepine | Chlorpyrifos | Cladribine | Cocaine | Copper | cupric chloride | Dextromethorphan | Dibutyl Phthalate | Diclofenac | Estradiol | Flame Retardants | hexabromocyclododecane | Imatinib Mesylate | Leflunomide | Lithium Chloride | Manganese | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Misoprostol | nonylphenol | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Polycyclic Aromatic Hydrocarbons | pyrazolanthrone | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | trichostatin A | tris(1,3-dichloro-2-propyl)phosphate | Valproic Acid | Vitamin A   212
50. glutathione biosynthetic process Abnormalities, Drug-Induced Inferred via 43 chemicals: 6-formylindolo(3,2-b)carbazole | Acetaminophen | Arachidonic Acid | Benzene | bisphenol A | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | Caffeine | Chloroquine | Cisplatin | cyanoginosin LR | cyclopamine | Cyclophosphamide | Dexamethasone | Dibutyl Phthalate | Diethylhexyl Phthalate | Doxorubicin | Ellagic Acid | Ethanol | Folic Acid | Freund's Adjuvant | Genistein | Ketoconazole | manganese chloride | Methamphetamine | Methimazole | Methotrexate | methylmercuric chloride | Methylmercury Compounds | naphthalene | Nicotine | Oxygen | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | Plant Preparations | Quercetin | Selenium | Smoke | Sulfasalazine | Tetrachlorodibenzodioxin | Tobacco Smoke Pollution   316
1–50 of 243,896 results.