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Disease Obesity

These diseases have comparable sets of interacting chemicals and genes to Obesity.

Via chemical associations

Similarity Index Common
Interacting
Chemicals
Insulin Resistance 0.18149 0.18149 51
Weight Gain 0.1794 0.1794 54
Glucose Intolerance 0.16268 0.16268 34
Diabetes Mellitus, Type 2 0.1375 0.1375 33
Non-alcoholic Fatty Liver Disease 0.13333 0.13333 26
Dyslipidemias 0.12832 0.12832 29
Fatty Liver 0.12766 0.12766 48
Hyperglycemia 0.1185 0.1185 41
Hyperlipidemias 0.11715 0.11715 28
Hyperinsulinism 0.11429 0.11429 20
Metabolic Syndrome 0.1027 0.1027 19
Diabetes Mellitus 0.09921 0.09921 25
Hypercholesterolemia 0.09562 0.09562 24
Diabetes Mellitus, Experimental 0.09205 0.09205 22
Depressive Disorder, Major 0.09174 0.09174 20
Cognition Disorders 0.09113 0.09113 37
Anxiety Disorders 0.09063 0.09063 30
Prenatal Exposure Delayed Effects 0.08945 0.08945 39
Atherosclerosis 0.08814 0.08814 26
Hypertriglyceridemia 0.08696 0.08696 20

Via marker/mechanism chemical associations

Similarity Index Common
Interacting
Chemicals
Insulin Resistance 0.18382 0.18382 25
Glucose Intolerance 0.17895 0.17895 17
Weight Gain 0.1686 0.1686 29
Diabetes Mellitus, Type 2 0.16071 0.16071 18
Dyslipidemias 0.15842 0.15842 16
Hypertriglyceridemia 0.13333 0.13333 14
Hyperinsulinism 0.12821 0.12821 10
Metabolic Syndrome 0.12 0.12 12
Hyperlipidemias 0.11765 0.11765 12
Diabetes Mellitus 0.11644 0.11644 17
Hyperglycemia 0.10843 0.10843 18
Birth Weight 0.10784 0.10784 11
Overweight 0.10606 0.10606 7
Non-alcoholic Fatty Liver Disease 0.10476 0.10476 11
Fatty Liver 0.10417 0.10417 25
Atherosclerosis 0.104 0.104 13
Puberty, Precocious 0.10256 0.10256 8
Hypercholesterolemia 0.09821 0.09821 11
Infertility, Female 0.09615 0.09615 10
Plaque, Atherosclerotic 0.09589 0.09589 7

Via therapeutic chemical associations

Similarity Index Common
Interacting
Chemicals
Weight Gain 0.15068 0.15068 22
Insulin Resistance 0.14724 0.14724 24
Fatty Liver 0.13072 0.13072 20
Non-alcoholic Fatty Liver Disease 0.10891 0.10891 11
Hyperglycemia 0.10363 0.10363 20
Diabetes Mellitus, Type 2 0.08759 0.08759 12
Glucose Intolerance 0.08661 0.08661 11
Dyslipidemias 0.08397 0.08397 11
Hyperlipidemias 0.08276 0.08276 12
Hypercholesterolemia 0.08 0.08 12
Diabetes Mellitus, Experimental 0.07692 0.07692 12
Liver Cirrhosis, Experimental 0.06667 0.06667 12
Hyperinsulinism 0.06604 0.06604 7
Liver Diseases 0.0625 0.0625 8
Atherosclerosis 0.0618 0.0618 11
Cognition Disorders 0.05946 0.05946 11
Brain Ischemia 0.05882 0.05882 9
Anxiety Disorders 0.05814 0.05814 10
Skin Neoplasms 0.05674 0.05674 8
Hypertrophy 0.0566 0.0566 6

Via gene associations

Similarity Index Common
Interacting
Genes
Insulin Resistance 0.13462 0.13462 28
Fatty Liver 0.12346 0.12346 30
Heart Failure 0.09653 0.09653 25
Diabetes Mellitus, Experimental 0.0963 0.0963 26
Atherosclerosis 0.08837 0.08837 19
Inflammation 0.08392 0.08392 24
Hypertension 0.08069 0.08069 28
Weight Gain 0.0717 0.0717 19
Diabetes Mellitus, Type 2 0.07042 0.07042 25
Diabetes Mellitus 0.06566 0.06566 13
Hyperlipidemias 0.06417 0.06417 12
Metabolic Syndrome 0.05789 0.05789 11
Carcinoma, Hepatocellular 0.05764 0.05764 23
Brain Ischemia 0.05677 0.05677 13
Alzheimer Disease 0.05512 0.05512 14
Cardiomegaly 0.05328 0.05328 13
Hyperinsulinism 0.05319 0.05319 10
Non-alcoholic Fatty Liver Disease 0.05189 0.05189 11
Reperfusion Injury 0.05019 0.05019 13
Seizures 0.04797 0.04797 13

Via marker/mechanism gene associations

Similarity Index Common
Interacting
Genes
Insulin Resistance 0.105 0.105 21
Fatty Liver 0.09322 0.09322 22
Heart Failure 0.08907 0.08907 22
Diabetes Mellitus, Experimental 0.08494 0.08494 22
Hypertension 0.07927 0.07927 26
Inflammation 0.07782 0.07782 20
Atherosclerosis 0.07353 0.07353 15
Weight Gain 0.0625 0.0625 16
Diabetes Mellitus, Type 2 0.06017 0.06017 21
Carcinoma, Hepatocellular 0.0582 0.0582 22
Diabetes Mellitus 0.05729 0.05729 11
Hyperlipidemias 0.05556 0.05556 10
Metabolic Syndrome 0.05435 0.05435 10
Alzheimer Disease 0.05372 0.05372 13
Brain Ischemia 0.05093 0.05093 11
Kidney Failure, Chronic 0.04348 0.04348 9
Albuminuria 0.04233 0.04233 8
Chemical and Drug Induced Liver Injury 0.04228 0.04228 23
Neoplasms 0.04167 0.04167 9
Liver Neoplasms 0.04152 0.04152 12

Via therapeutic gene associations

Similarity Index Common
Interacting
Genes
Non-alcoholic Fatty Liver Disease 0.27273 0.27273 3
Fatty Liver 0.25 0.25 4
Weight Gain 0.21429 0.21429 3
Insulin Resistance 0.21053 0.21053 4
Heart Failure 0.16667 0.16667 3
Glucose Intolerance 0.14286 0.14286 2
Poisoning 0.13333 0.13333 2
Myocardial Reperfusion Injury 0.11765 0.11765 2
Diabetes Mellitus, Type 2 0.11111 0.11111 2
Hyperkinesis 0.10526 0.10526 2
Diabetes Mellitus, Experimental 0.1 0.1 2
Cardiotoxicity 0.09091 0.09091 1
Coma 0.09091 0.09091 1
Coronary Restenosis 0.09091 0.09091 1
Hyperphagia 0.09091 0.09091 1
Obesity, Morbid 0.09091 0.09091 1
Scleroderma, Systemic 0.09091 0.09091 1
Tachycardia 0.09091 0.09091 1
Apnea 0.08333 0.08333 1
Death 0.08333 0.08333 1
Demyelinating Diseases 0.08333 0.08333 1
Encephalomyelitis, Autoimmune, Experimental 0.08333 0.08333 1
Hyperlipidemias 0.08333 0.08333 1
Hypothermia 0.08333 0.08333 1
Oral Ulcer 0.08333 0.08333 1
Paralysis 0.08333 0.08333 1
Stomach Diseases 0.08333 0.08333 1