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Disease Pathologic Processes

These are exposure studies associated with the disease and all of its children.

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1–50 of 188 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Choi H, et al. (2008). Prenatal polycyclic aromatic hydrocarbon exposure is likely to contribute to the occurrence of small size for gestational age as well as preterm births among African Americans. 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | indeno(1,2,3-cd)pyrene | Polycyclic Aromatic Hydrocarbons Pregnant females United States air 1,12-benzoperylene | 1,2,5,6-dibenzanthracene | benz(a)anthracene | Benzo(a)pyrene | benzo(b)fluoranthene | benzo(k)fluoranthene | chrysene | indeno(1,2,3-cd)pyrene | Polycyclic Aromatic Hydrocarbons Details Fetal Growth Retardation | Premature Birth | Prenatal Exposure Delayed Effects
2. Perry MJ, et al. (2016). Organochlorine exposures measured at age 14 and in adulthood were associated with sperm disomy in this sample of high-exposure men, suggesting that the impacts of persistent pollutants on testicular maturation and function require further investigation. 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 Children | Infants or newborns | Study subjects Faroe Islands blood, cord | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,3',4,4',5-pentachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | PCB 180 | Polychlorinated Biphenyls Details Aneuploidy | male meiosis chromosome separation
3. Lopez-Espinosa MJ, et al. (2016). INfancia y Medio Ambiente (INMA) Project To our knowledge, this is the first study to report an association between prenatal exposure to some polychlorinated biphenyls and hexachlorobenzene and fetal growth: abdominal circumference during the first two trimesters of pregnancy, and biparietal diameter and femur length later in pregnancy. 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | PCB 180 | Polychlorinated Biphenyls Fetuses | Infants or newborns | Pregnant females Spain blood, cord | serum 2,2',3',4,4',5-hexachlorobiphenyl | 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene | Hexachlorobenzene | PCB 180 Details Fetal Growth Retardation
4. Casas M, et al. (2015). Children's Health and the Environment in the Faroes | Flemish Environment and Health Survey (FLEHS I) | INfancia y Medio Ambiente (INMA) Project | Norwegian Human Milk Study (HUMIS) | PELAGIE This study suggests that the association between low-level exposure to PCB153 and birth weight exists and follows an inverse linear exposure-response relationship with effects even at low levels, and that maternal smoking and ethnicity modify this association. race | tobacco 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Fetuses | Infants or newborns | Pregnant females Belgium|Faroe Islands|
France|Germany|
Greece|Greenland|
Norway|Poland|
Slovakia|Spain|
Ukraine
blood | milk, human | plasma, cord | serum | serum, cord 2,4,5,2',4',5'-hexachlorobiphenyl | Dichlorodiphenyl Dichloroethylene Details Birth Weight | Fetal Growth Retardation | Prenatal Exposure Delayed Effects
5. Waggoner JK, et al. (2013). Agricultural Health Study (AHS) In this large cohort of male farmers, pesticide use, in addition to farm machinery use, was associated with fatal injury. 2,4,5-Trichlorophenoxyacetic Acid | 2,4-Dichlorophenoxyacetic Acid | alachlor | butylate | Carbon Disulfide | Carbon Tetrachloride | cyanazine | metribuzin | Paraquat | Ziram Workers United States Details Death
6. No authors listed. (2000). This report describes the five deaths associated with 2,4-DCP exposure (presented in the order in which they were identified) and provides recommendations for preventing additional deaths. 2,4-dichlorophenol Workers France|United Kingdom|
United States
bile | blood | serum | stomach | urine 2,4-dichlorophenol Details Acute Disease | Burns, Chemical | Death | Poisoning | Seizures
7. Munger R, et al. (1997). We conclude that communities in southern Iowa with drinking water supplies contaminated with herbicides have elevated rates of intrauterine growth retardation compared to neighboring communities with different water supplies. 2,4-Dichlorophenoxyacetic Acid | 2-xylene | 3-xylene | 4-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane Pregnant females United States water, drinking 2,4-Dichlorophenoxyacetic Acid | 2-xylene | alachlor | Atrazine | bromodichloromethane | bromoform | chlorodibromomethane | Chloroform | cyanazine | metolachlor | tetrachloroethane | Xylenes Details Fetal Growth Retardation
8. Jiménez-Garza O, et al. (2017). Our results demonstrate alterations in the inflammation pathway at the epigenetic level associated with exposure to benzene. Acetone | Benzene | ethylbenzene | methyl acetate | methylethyl ketone | n-hexane | Toluene | Xylenes Workers Mexico air Acetone | Benzene | ethylbenzene | methyl acetate | methylethyl ketone | n-hexane | Toluene | Xylenes Details Inflammation | inflammatory response | methylation
9. Pedersen M, et al. (2012). Dietary exposure to acrylamide was associated with reduced birth weight and head circumference. Consumption of specific foods during pregnancy was associated with higher acrylamide exposure in utero diet Acrylamide | Tobacco Smoke Pollution Fetuses | Pregnant females Denmark|Greece|
Norway|Spain|
United Kingdom
blood, cord Acrylamide | Ethylene Oxide | glycidamide Details Birth Weight | Fetal Growth Retardation | Prenatal Exposure Delayed Effects | head development
10. Shirima CP, et al. (2015). We investigated the association between child growth and aflatoxin and fumonisin exposure in Tanzania. Aflatoxins | fumonisin B1 Children Tanzania, United Republic of plasma | urine aflatoxin-albumin adduct | fumonisin B1 Details Growth Disorders
11. López-Villarrubia E, et al. (2010). Our findings indicate the existence of a short-term association between current exposure levels to air pollutants and total mortality as well as mortality due to heart and respiratory diseases in both Canary cities studied along with evidence that the association on a given day may spread over several successive days. Air Pollutants Spain air Carbon Monoxide | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Death | Heart Diseases | Respiratory Tract Diseases
12. Dehbi HM, et al. (2017). National Survey of Health and Development (NSHD) | Southall And Brent Revisited (SABRE) Study We examined associations between air pollution and cardiovascular disease mortality in two British cohorts with over 25 years of follow-up; our results support a detrimental long-term effect for air pollutants on cardiovascular mortality. Air Pollutants Study subjects United Kingdom air, ambient Nitrogen Dioxide | Nitrogen Oxides | Particulate Matter | Smoke | Sulfur Dioxide Details Cardiovascular Diseases | Death
13. Schwartz J, et al. (2017). We conclude that there is a causal association of local air pollution with daily deaths at concentrations below U.S. EPA standards; the estimated attributable risk in Boston exceeded 1,800 deaths during the study period. Air Pollutants Study subjects United States air, ambient Nitrogen Dioxide | Particulate Matter | Soot Details Death
14. Andersen ZJ, et al. (2012). Danish Diet, Cancer, and Health Study (DCH) Long-term exposure to traffic-related air pollution may contribute to the development of ischemic but not hemorrhagic stroke, especially severe ischemic strokes leading to death within 30 days. Air Pollutants Study subjects Denmark Nitrogen Dioxide Details Brain Ischemia | Cerebral Hemorrhage | Stroke
15. Bentayeb M, et al. (2015). GAZEL Cohort Study We analyzed the association between long-term exposure to air pollution and mortality in a large French cohort (from 1989-2013), and found that long-term exposure to fine particular matter, nitrogen dioxide, sulfur dioxide and benzene is associated with an increased risk of non-accidental mortality. Air Pollutants Study subjects France air, ambient Benzene | Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Death
16. López-Abente G, et al. (2012). Statistically significant relative risks for colorectal cancer mortality at a municipal level were detected in the vicinity of mining industry, paper and wood production, food and beverage sector, metal production and processing installations, and ceramics. Air Pollutants Study subjects Spain air, outdoor 1,1,1-trichloroethane | Ammonia | anthracene | Antimony | Arsenicals | Arsenic | Benzene | beta-hexachlorocyclohexane | Cadmium | Cadmium Compounds | Carbon Dioxide | Carbon Monoxide | Carbon Tetrachloride | Chlorine | Chlorine Compounds | Chlorofluorocarbons | Chloroform | Chromium | Chromium Compounds | Cobalt | Diethylhexyl Phthalate | Dioxins | ethylene dichloride | Ethylene Oxide | Fluorine | Fluorine Compounds | Hexachlorobenzene | Hydrogen Cyanide | Lead | Manganese | Manganese Compounds | Mercury | Mercury Compounds | Methane | Methylene Chloride | naphthalene | Nickel | Nitrogen Oxides | Nitrous Oxide | Particulate Matter | Pentachlorophenol | Polychlorinated Biphenyls | Sulfur Oxides | Tetrachloroethylene | Thallium | trichlorobenzene | Trichloroethylene | Vanadium | Vanadium Compounds | Vinyl Chloride | Zinc | Zinc Compounds Details Colorectal Neoplasms | Death
17. Hansell A, et al. (2016). Office for National Statistics Longitudinal Study This large national study suggests that air pollution exposure has long-term effects on mortality that persist decades after exposure, and that historic air pollution exposures influence current estimates of associations between air pollution and mortality. Air Pollutants Study subjects United Kingdom air, ambient Particulate Matter | Soot | Sulfur Dioxide Details Death | Respiratory Tract Diseases
18. César AC, et al. (2015). Even at nitrogen oxides concentrations below the acceptable standard, there is association with deaths caused by respiratory diseases. Air Pollutants Study subjects Brazil air, ambient Carbon Monoxide | Nitrogen Oxides | Ozone | Particulate Matter Details Death | Respiration Disorders
19. Medina-Ramón M, et al. (2008). Worcester Heart Attack Study Residential exposure to traffic-related air pollution increases the mortality risk after hospitalization with acute heart failure. Air Pollutants Subjects with disease:Heart Failure United States Details Death
20. Zhang F, et al. (2011). Study on the association between ambient air pollution and daily cardiovascular and respiratory mortality in an urban district of Beijing. Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
21. Ranzi A, et al. (2011). No increased risk of mortality and morbidity was found in the entire area among people living close to incinerators. The internal analysis of the cohort based on dispersion modeling found excesses of mortality for some cancer types in the highest exposure categories, especially in women. People in the highest heavy metal exposure categories tended to have a lower socioeconomic status than those in the lowest categories. The interpretation of the findings is limited given the pilot nature of the study sex | socioeconomic status Air Pollutants Study subjects Italy waste, industrial Cadmium | Dioxins | Mercury | Metals, Heavy | Nitrogen Dioxide | Particulate Matter Details Breast Neoplasms | Colorectal Neoplasms | Death | Liver Neoplasms | Neoplasms | Stomach Neoplasms
22. Lin H, et al. (2017). Hourly peak concentration may capture health effects of ambient fine particulate matter pollution (PM2.5) better than daily averages; significant associations were found between hourly peak PM2.5 concentrations and cardiovascular mortality, particularly from ischemic heart diseases and cerebrovascular diseases. Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Ozone | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Cerebrovascular Disorders | Death | Myocardial Ischemia
23. O'Neal WT, et al. (2017). Reasons for Geographic And Racial Differences in Stroke (REGARDS) Long-term, but not short-term, exposure to particulate matter PM2.5 is associated with premature atrial contractions, suggesting a role for long-term PM2.5 in initiating supraventricular arrhythmias triggered by such contractions. Air Pollutants Controls for disease:Atrial Premature Complexes | Subjects with disease:Atrial Premature Complexes United States air, ambient Particulate Matter Details Atrial Premature Complexes
24. Filleul L, et al. (2003). We found a significant association between daily mortality and black smoke among the elderly in Bordeaux. age | sex Air Pollutants Study subjects France air Air Pollutants Details Death
25. Zhang P, et al. (2011). Long-term exposure to ambient air pollution is associated with the death of cardiovascular and cerebrovascular diseases among Chinese populations. The effects of air pollution were more evident in female that in male, and nonsmokers and residents with body mass index less than 18.5 were more vulnerable to outdoor air pollution. body mass index | sex | tobacco Air Pollutants Study subjects China air, ambient Nitrogen Dioxide | Particulate Matter | Sulfur Dioxide Details Cardiovascular Diseases | Cerebrovascular Disorders | Death
26. Zúñiga J, et al. (2016). There could be an association between the air pollution in Panama City (Panama) and an increase in cardiovascular and respiratory mortality. Air Pollutants | Nitrogen Dioxide | Ozone | Particulate Matter Study subjects Panama air, ambient Nitrogen Dioxide | Ozone | Particulate Matter Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
27. Penn SL, et al. (2017). Our findings reinforce the importance of pollutant-specific, location-specific, and source-specific models of health impacts in design of health-risk minimizing emissions control policies. Air Pollutants | Nitrogen Oxides | Particulate Matter | Sulfur Dioxide | Volatile Organic Compounds Study subjects United States air Nitrogen Oxides | Particulate Matter | Sulfur Dioxide | Volatile Organic Compounds Details Death
28. Pearce MS, et al. (2012). Particulate Matter and Perinatal Events Research (PAMPER) Association was observed between socio-economic deprivation and particulate matter on birth weight, with increasing effects of particulate matter in reducing birth weight seen with increasing socio-economic disadvantage. socioeconomic status Air Pollutants | Particulate Matter Fetuses | Pregnant females United Kingdom air Particulate Matter Details Birth Weight | Fetal Growth Retardation
29. Pope CA 3RD, et al. (2011). American Cancer Society Cancer Prevention Study II (ACS CPS-II) The exposure-response relationship associated with PM2.5 is qualitatively different for lung cancer versus cardiovascular mortality. At low exposure levels, cardiovascular deaths are projected to account for most of the burden of disease, whereas at high levels of PM2.5, lung cancer becomes proportionately more important. tobacco Air Pollutants | Particulate Matter Study subjects United States cigarette Particulate Matter Details Cardiovascular Diseases | Death | Lung Neoplasms
30. Goodman PG, et al. (2004). We assessed the associations of particulate pollution (black smoke) and temperature with age-standardized daily mortality rates over 17 years in Dublin, Ireland, using a polynomial distributed lag model of both temperature and particulate air pollution simultaneously through 40 days after exposure. Air Pollutants | Particulate Matter | Smoke Study subjects Ireland air Smoke Details Cardiovascular Diseases | Death | Respiratory Tract Diseases
31. Stevens GA, et al. (2008). In this study, we used data on exposure to 3 major environmental risks (unsafe water and sanitation, indoor air pollution from household solid fuel use, and ambient urban PM pollution) and on cause-specific mortality at the county level in Mexico to estimate the mortality effects of these 3 risks at the county level. socioeconomic status Air Pollutants | Particulate Matter | Water Pollutants Study subjects Mexico Details Death
32. Higuchi K, et al. (2012). This study showed that Mt. Sakurajima's volcanic activities increased the mortality of lung cancer and chronic obstructive pulmonary diseases in the Sakurajima-Tarumizu area, which has the largest amount of ashfall from the volcano in its vicinity. Air Pollutants | Silicon Dioxide Study subjects Japan Air Pollutants | Silicon Dioxide Details Death | Lung Neoplasms | Pulmonary Disease, Chronic Obstructive | Respiration Disorders
33. Monrad M, et al. (2017). Danish Diet, Cancer, and Health Study (DCH) We found long-term residential traffic-related air pollution to be associated with higher risk of atrial fibrillation. Air Pollutants | Vehicle Emissions Study subjects Denmark air, ambient Nitrogen Dioxide | Nitrogen Oxides Details Atrial Fibrillation
34. Zhang W, et al. (1994). We report early health effects and biological monitoring in persons occupationally exposed to tetraethyl lead in China for the years 1990-1992, including for gasoline depot workers and traffic police officers. Air Pollutants, Occupational | Tetraethyl Lead Workers China air, ambient | urine diethyllead | Lead | triethyllead Details Bradycardia | Tremor
35. Wu M, et al. (2010). These findings confirm the previously reported association between World Trade Center dust exposure and bronchiolar and interstitial lung disease. Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Workers United States lung Aluminum Silicates | Asbestos, Serpentine | Calcium Sulfate | Magnesium Silicates | Nanotubes, Carbon Details Bronchiolitis | Fibrosis | Metaplasia | Pneumonia
36. Moon KA, et al. (2013). Strong Heart Study (SHS) Low to moderate chronic arsenic exposure, as measured in urine, was prospectively associated with cardiovascular disease incidence and mortality. Arsenic Study subjects United States urine Arsenic Details Cardiovascular Diseases | Coronary Disease | Death | Stroke
37. Rahman M, et al. (2014). The result suggests that arsenic exposure from drinking water was associated with increased stroke mortality risk and was more significant in women compared to men. diet | sex Arsenic Controls for disease:Death | Subjects with disease:Death | Controls for disease:Stroke | Subjects with disease:Stroke | Study subjects Bangladesh water, well Arsenic Details Death | Stroke
38. Smith AH, et al. (1998). In conclusion, markedly increased cancer risks have been found in this study in Chile to be associated with arsenic in drinking water. Arsenic Study subjects Chile water, drinking Arsenic Details Death | Kidney Neoplasms | Lung Neoplasms | Skin Neoplasms | Urinary Bladder Neoplasms
39. Chen CJ, et al. (1996). In this study, we observed a significantly increased ischemic heart disease (ISHD) mortality among residents in the blackfoot disease (BFD)-endemic area, a significantly higher ISHD mortality for BFD patients than for age-, sex-, and residence-matched control subjects, and a dose-response relation between ISHD mortality and long-term exposure to ingested inorganic arsenic. age | disease Arsenic Controls for disease:Peripheral Vascular Diseases | Subjects with disease:Peripheral Vascular Diseases Taiwan, Province of China water, drinking Arsenic Details Death | Myocardial Ischemia
40. Wade TJ, et al. (2009). This is the first study to document increased arsenic-associated mortality in the Bayingnormen Inner Mongolia region of China. Arsenic Study subjects China water Arsenic Details Coronary Disease | Death | Neoplasms
41. Chen Y, et al. (2011). Exposure to arsenic in drinking water is adversely associated with mortality from heart disease, especially among smokers. tobacco Arsenic Study subjects Bangladesh urine | water, drinking Details Cardiovascular Diseases | Death | Myocardial Ischemia
42. Smith AH, et al. (2012). Taking together our findings in the present study and previous evidence of increased mortality from other causes of death, we conclude that arsenic in Antofagasta drinking water has resulted in the greatest increases in mortality in adults < 50 years of age ever associated with early-life environmental exposure. Arsenic Study subjects Chile Details Cardiovascular Diseases | Death | Female Urogenital Diseases | Kidney Diseases | Laryngeal Neoplasms | Liver Neoplasms | Male Urogenital Diseases | Neoplasms | Urinary Bladder Neoplasms
43. Guo X, et al. (2003). The present study indicated that there was a high odds ratio of subjective symptoms including cough, stomachache, palpitations, urination problems and spontaneous abortion amongst residents in the arsenic-affected village. Arsenic Controls for disease:Skin Diseases | Subjects with disease:Skin Diseases | Study subjects Mongolia water, well Arsenic Details Abortion, Spontaneous | Arrhythmias, Cardiac | Cough | Stomach Diseases | Urinary Bladder Diseases
44. D'Ippoliti D, et al. (2015). Results provide new evidence for risk assessment of low-medium concentrations of arsenic and contribute to the ongoing debate about the threshold-dose of effect, suggesting that even concentrations below 10 micrograms per liter carry a mortality risk. sex Arsenic Study subjects Italy Arsenic Details Death | Diabetes Mellitus | Lung Neoplasms | Myocardial Infarction | Peripheral Arterial Disease | Pulmonary Disease, Chronic Obstructive
45. Cui N, et al. (2016). Long-term exposure to arsenic is associated with upregulated mRNA expression for genes AHR and CYP1A1 in the blood, and blood CYP1A1 mRNA (but not AHR mRNA) is associated with prolonged corrected QT interval. diet Arsenic Study subjects China blood | water, drinking AHR | Arsenic | CYP1A1 Details Long QT Syndrome | regulation of heart rate
46. Paul S, et al. (2014). We infer that arsenic biotransformation leads to promoter hypomethylation of ERCC2, which in turn inhibits the normal functioning of the Cdk-activating kinase complex, thus affecting DNA repair; this effect was highest among the arsenic exposed individuals with dermatological lesions. Arsenic Controls for disease:Skin Diseases | Subjects with disease:Skin Diseases | Study subjects India blood | hair | leukocyte, mononuclear | nail | urine | water, drinking Arsenic | CDK7 | ERCC2 Details Micronuclei, Chromosome-Defective | Skin Diseases | positive regulation of DNA repair
47. Chen Y, et al. (2013). Health Effects of Arsenic Longitudinal Study (HEALS) Long-term arsenic exposure from drinking water (average 95 micrograms per liter; range, 0.1-790 micrograms per liter) was associated with subsequent QT-interval prolongation in women. sex Arsenic Controls for disease:Arrhythmias, Cardiac | Subjects with disease:Arrhythmias, Cardiac Bangladesh urine | water, well Arsenic Details Arrhythmias, Cardiac
48. Thurston GD, et al. (2016). American Cancer Society Cancer Prevention Study II (ACS CPS-II) Long-term fine particulate matter (PM2.5) exposures from fossil fuel combustion, especially coal burning but also from diesel traffic, were associated with increases in ischemic heart disease mortality in this nationwide population. Arsenic | Carbon | Chlorine | Iron | Lead | Manganese | Particulate Matter | Potassium | Selenium | Silicon | Soot | Sulfur Study subjects United States air, ambient | soil Arsenic | Calcium | Carbon | Chlorine | Iron | Lead | Manganese | Nickel | Particulate Matter | Potassium | Selenium | Silicon | Sodium | Soot | Sulfur | Vanadium | Zinc Details Death | Myocardial Ischemia
49. Keil AP, et al. (2017). Lee-Fraumeni Cohort Our analyses suggest that the excess deaths from causes other than respiratory cancers comprise the majority of the excess deaths caused by inhaled arsenic exposure. arsenic trioxide Workers United States air arsenic trioxide Details Death | Heart Diseases | Respiratory Tract Neoplasms
50. Kukkonen MK, et al. (2014). Our results support the hypothesis that the inflammasome is important in the development of fibrotic lung disease by associating the NLRP3 rs35829419 variant allele with increased risk of asbestos-related interstitial lung fibrosis, and the TGFB1 rs2241718 variant allele with decreased risk of asbestos-related visceral pleural fibrosis; polymorphisms in CARD8 and TIMP2 are proposed to modify the development and/or calcification of pleural thickenings. genetics Asbestos Subjects with gene influence:CARD8 | Subjects with gene influence:NLRP3 | Subjects with gene influence:TGFB1 | Subjects with gene influence:TIMP2 | Workers Finland Details Asbestosis | Calcinosis | Fibrosis | Occupational Diseases | Pleural Diseases
1–50 of 188 results.