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Disease Overweight

These phenotypes are associated with Overweight or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 7,556 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. apoptotic process Obesity Inferred via 72 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | Bezafibrate | bisphenol A | C646 compound | Cadmium | Caffeine | Capsaicin | Chlorpyrifos | Chromium | Clozapine | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Dihydrotestosterone | Enalapril | Estrogens | Fatty Acids, Nonesterified | Fenretinide | Fluoxetine | Folic Acid | Fructose | glabridin | Glutathione | Hydrocortisone | Lead | Lithium | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercury | Metformin | NAD | Naproxen | naringenin | Nicotine | Olanzapine | Oleanolic Acid | Orlistat | Particulate Matter | Pioglitazone | pirinixic acid | Plant Extracts | Poloxamer | Polychlorinated Biphenyls | Prednisolone | pregna-4,17-diene-3,16-dione | Quercetin | Quetiapine Fumarate | Resveratrol | Rimonabant | Rosiglitazone | Sertraline | sibutramine | Streptozocin | Sucrose | Telmisartan | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 17 genes: ADRB1 | AHR | AKT1 | CASP1 | CIDEA | CYCS | DDIT3 | EP300 | FOXO3 | GPX1 | HMOX1 | PARP1 | PPARD | SIRT1 | TF | TNF | TNFRSF1B 993
2. cell proliferation Obesity Inferred via 65 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | C646 compound | Cadmium | Caffeine | Capsaicin | Chlorpyrifos | Clozapine | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Dihydrotestosterone | Enalapril | Estrogens | Excitatory Amino Acid Agents | Fenretinide | Fluoxetine | Folic Acid | Fructose | glabridin | Glutathione | Halogenated Diphenyl Ethers | Harmine | Hydrocortisone | Lead | Lithium | Manganese | Mercury | Metformin | Methoxychlor | naringenin | Nicotine | Olanzapine | Oleanolic Acid | Orlistat | Particulate Matter | Pioglitazone | pirinixic acid | Plant Extracts | Polychlorinated Biphenyls | Polylysine | Prednisolone | Quercetin | Resveratrol | Rimonabant | Rosiglitazone | Streptozocin | Topiramate | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 10 genes: ACHE | AKT1 | CTF1 | GCG | GH1 | GLUL | GPX1 | PPARD | PYY | WNT3A 853
3. cell death Obesity Inferred via 55 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-chloroethyl ethyl sulfide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | Bezafibrate | bisphenol A | C646 compound | Cadmium | Caffeine | Capsaicin | Chlorpyrifos | Clozapine | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Enalapril | Estrogens | Excitatory Amino Acid Agents | Fatty Acids, Nonesterified | Fenretinide | Fluoxetine | Glutathione | Halogenated Diphenyl Ethers | Harmine | Lead | Lithium | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercury | Metformin | Methoxychlor | NAD | naringenin | Nicotine | Oleanolic Acid | Orlistat | Particulate Matter | pirinixic acid | Plant Extracts | Quercetin | Resveratrol | Rimonabant | Rosiglitazone | sibutramine | Streptozocin | Topiramate | Valproic Acid | Vehicle Emissions Inferred via 3 genes: CIDEA | HMOX1 | HTR2A 469
4. lipid catabolic process Obesity Inferred via 52 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Capsaicin | Chlorpyrifos | Cholesterol, Dietary | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Dihydrotestosterone | Enalapril | Ephedrine | Folic Acid | Fructose | glabridin | Glutathione | Hydrocortisone | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercury | Metformin | NAD | naringenin | Nicotine | Orlistat | Particulate Matter | Pioglitazone | Plant Extracts | Prednisolone | Quercetin | Resveratrol | Rimonabant | Rosiglitazone | sibutramine | Streptozocin | Telmisartan | Topiramate | Water Pollutants, Chemical | Yohimbine Inferred via 4 genes: IRS1 | LPL | PCK1 | PLIN1 467
5. response to oxidative stress Obesity Inferred via 51 chemicals: 4-hydroxy-2-nonenal | Acarbose | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Capsaicin | Clozapine | Cromolyn Sodium | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Enalapril | Estrogens | Fenretinide | Fluoxetine | Fructose | Glutathione | Glutathione Disulfide | Hydrocortisone | Lead | Lithium | Manganese | Mercury | NAD | Naproxen | Nicotine | Olanzapine | Particulate Matter | Pioglitazone | Plant Extracts | Quercetin | Quetiapine Fumarate | Resveratrol | Rimonabant | Risperidone | Rosiglitazone | Streptozocin | Telmisartan | Topiramate | Valproic Acid | Vehicle Emissions | Yohimbine Inferred via 16 genes: AKT1 | APOE | CA3 | CYCS | DDIT3 | ETFDH | GPX1 | GPX3 | HMOX1 | MMP9 | NEIL1 | NQO1 | PTGS2 | SIRT1 | SOD1 | SOD2 402
6. positive regulation of cell death Obesity Inferred via 45 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-chloroethyl ethyl sulfide | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Chlorpyrifos | Clozapine | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Environmental Pollutants | Fatty Acids, Nonesterified | Fenretinide | Fluoxetine | Fluvoxamine | Folic Acid | Glutathione | Halogenated Diphenyl Ethers | Hydrocortisone | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mianserin | Naproxen | Nicotine | Particulate Matter | Plant Extracts | Polychlorinated Biphenyls | Prednisolone | Quercetin | raspberry ketone | Resveratrol | Rosiglitazone | Sertraline | Streptozocin | Thallium | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions Inferred via 5 genes: AKR1C3 | EP300 | MIR34A | PTGS2 | UCP2 268
7. glutathione biosynthetic process Obesity Inferred via 44 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Chlorpyrifos | Clozapine | Cobalt | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Folic Acid | Fructose | Glutathione | Lead | Manganese | Mercury | Metformin | NAD | naringenin | Nicotine | Oleanolic Acid | Orlistat | Particulate Matter | Pioglitazone | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Telmisartan | Topiramate | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical | Yohimbine   404
8. superoxide dismutase activity Obesity Inferred via 43 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Capsaicin | Chlorpyrifos | Cholesterol, Dietary | cobaltiprotoporphyrin | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Fructose | Glutathione | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercury | Metformin | naringenin | Nicotine | Oleanolic Acid | Orlistat | Particulate Matter | Phthalic Acids | Pioglitazone | Plant Extracts | Prednisolone | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Telmisartan | Topiramate | Vehicle Emissions | Water Pollutants, Chemical | Yohimbine Inferred via 3 genes: NQO1 | SOD1 | SOD2 386
9. regulation of blood pressure Obesity Inferred via 42 chemicals: Acarbose | Acetylcysteine | Ascorbic Acid | Bezafibrate | Caffeine | Canrenoic Acid | Capsaicin | Cyclosporine | Dexfenfluramine | Dietary Sucrose | Diethylstilbestrol | Enalapril | Ephedrine | Fluoxetine | Folic Acid | Fructose | Glutathione | Hydrocortisone | Lead | Manganese | Mazindol | Mercury | Metformin | Mianserin | NAD | Naproxen | Nicotine | Orlistat | Particulate Matter | Pioglitazone | Plant Extracts | Quercetin | Rosiglitazone | Sertraline | sibutramine | Streptozocin | Telmisartan | Topiramate | Trazodone | Valproic Acid | Vehicle Emissions | Yohimbine Inferred via 10 genes: AHR | GNB3 | HMOX1 | LEP | NPY1R | POMC | PPARG | PTGS2 | SOD1 | SOD2 450
10. regulation of mitochondrial membrane potential Obesity Inferred via 42 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Capsaicin | Chlorpyrifos | Clozapine | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | Dietary Fats | Diethylhexyl Phthalate | Dihydrotestosterone | Ephedrine | Fenretinide | Fructose | Glutathione | Halogenated Diphenyl Ethers | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | naringenin | Nicotine | Olanzapine | Particulate Matter | Plant Extracts | Quercetin | Quetiapine Fumarate | Resveratrol | Risperidone | Rosiglitazone | sibutramine | Streptozocin | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 3 genes: SOD1 | SOD2 | UCP2 315
11. positive regulation of apoptotic process Obesity Inferred via 41 chemicals: 2-chloroethyl ethyl sulfide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | Barium | bisphenol A | Cadmium | Chlorpyrifos | Chromium | Cobalt | cobaltiprotoporphyrin | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Estrogens | Fatty Acids, Nonesterified | Fructose | Glutathione | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | naringenin | Nicotine | Olanzapine | Panax notoginseng extract | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 20 genes: ADRB1 | ADRB2 | AKT1 | CASP1 | CNR1 | CYP1B1 | DDIT3 | FOXO3 | HMOX1 | IDO1 | IL6 | KCNMA1 | MIR21 | MMP9 | PPARG | PTGS2 | SIRT1 | SOD1 | TNF | TRPV1 374
12. positive regulation of reactive oxygen species biosynthetic process Obesity Inferred via 41 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | cobaltiprotoporphyrin | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Enalapril | evodiamine | Fenretinide | Fluoxetine | Glutathione | GW 4064 | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | Mianserin | naringenin | Oleanolic Acid | Particulate Matter | pirinixic acid | Plant Extracts | Quercetin | raspberry ketone | Resveratrol | Rosiglitazone | Streptozocin | Thallium | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 1 gene: FOXO3 329
13. positive regulation of cell proliferation Obesity Inferred via 38 chemicals: 2-chloroethyl ethyl sulfide | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | Ascorbic Acid | bisphenol A | Calcifediol | Capsaicin | Chlorpyrifos | cobaltiprotoporphyrin | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Dihydrotestosterone | Fenretinide | Fluoxetine | Folic Acid | Glutathione | GW 4064 | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Margarine | Metformin | Methoxychlor | NAD | naringenin | Nicotine | Panax notoginseng extract | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Valproic Acid | Water Pollutants, Chemical Inferred via 24 genes: ADRB2 | AKR1C3 | AKT1 | CTF1 | F2 | FGF21 | GNAS | HTR2A | IGF2 | IL6 | INS | IRS1 | KITL | LEP | MIR21 | NAMPT | NPY5R | NTRK2 | PPARD | PTGS2 | SIRT1 | STS | TNF | WNT3A 330
14. membrane lipid catabolic process Obesity Inferred via 36 chemicals: 4-hydroxy-2-nonenal | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Capsaicin | Curcumin | Cyclosporine | deoxynivalenol | Dietary Carbohydrates | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Enalapril | Fructose | Glutathione | Glutathione Disulfide | Lead | Lithium | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | NAD | Naproxen | Nicotine | Pioglitazone | Plant Extracts | Quercetin | Quetiapine Fumarate | Resveratrol | Risperidone | Rosiglitazone | Streptozocin | Telmisartan | Topiramate | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Water Pollutants, Chemical Inferred via 1 gene: CYP1B1 214
15. reactive oxygen species biosynthetic process Obesity Inferred via 36 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | C646 compound | Cadmium | Chlorpyrifos | Cobalt | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Fluoxetine | Fructose | Glutathione | Halogenated Diphenyl Ethers | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercury | naringenin | Nicotine | Particulate Matter | Plant Extracts | Poloxamer | Quercetin | Resveratrol | sibutramine | Streptozocin | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical   386
16. glutathione metabolic process Obesity Inferred via 35 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | Cholesterol, Dietary | cobaltiprotoporphyrin | Curcumin | Cyclosporine | deoxynivalenol | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Enalapril | Environmental Pollutants | Fatty Acids, Nonesterified | Fenretinide | Fluoxetine | Folic Acid | Fructose | Glutathione | Glutathione Disulfide | Lead | Particulate Matter | Plant Extracts | Poloxamer | Quercetin | Resveratrol | Rosiglitazone | Sertraline | Streptozocin | Thallium | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid | Vehicle Emissions Inferred via 4 genes: GPX1 | GPX3 | SOD1 | SOD2 439
17. glutathione peroxidase activity Obesity Inferred via 35 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Chlorpyrifos | Cholesterol, Dietary | Clozapine | Curcumin | Cyclosporine | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Dietary Carbohydrates | Dietary Fats | Diethylnitrosamine | Folic Acid | Fructose | Lead | Manganese | Mercury | Metformin | naringenin | Nicotine | Orlistat | Particulate Matter | Pioglitazone | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Telmisartan | Vehicle Emissions | Water Pollutants, Chemical Inferred via 2 genes: GPX1 | GPX3 308
18. triglyceride biosynthetic process Obesity Inferred via 35 chemicals: 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate | Acetylcysteine | Bezafibrate | bisphenol A | Cadmium | Capsaicin | Cholesterol, Dietary | Clozapine | Curcumin | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Dietary Sugars | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Fatty Acids, Nonesterified | Folic Acid | Fructose | herbacetin | Metformin | naringenin | Nicotine | Particulate Matter | Pioglitazone | Plant Extracts | Polychlorinated Biphenyls | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Sucrose | Telmisartan | Valproic Acid | Water Pollutants, Chemical Inferred via 2 genes: ACSL1 | LPL 235
19. cholesterol biosynthetic process Obesity Inferred via 34 chemicals: 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol | 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate | Acetylcysteine | Aripiprazole | Bezafibrate | bisphenol A | Cadmium | Caffeine | Capsaicin | Cholesterol, Dietary | Clozapine | Curcumin | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Dietary Sugars | Diethylhexyl Phthalate | Diethylnitrosamine | Fatty Acids, Nonesterified | Fructose | herbacetin | Metformin | naringenin | Nicotine | Particulate Matter | Pioglitazone | Plant Extracts | Polychlorinated Biphenyls | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Telmisartan | Vehicle Emissions Inferred via 2 genes: ACLY | CES1 203
20. DNA damage response, detection of DNA damage Obesity Inferred via 33 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | cetilistat | Curcumin | deoxynivalenol | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Environmental Pollutants | Glutathione | Halogenated Diphenyl Ethers | Manganese | Metformin | NAD | naringenin | Nicotine | Particulate Matter | Plant Extracts | Polychlorinated Biphenyls | Quercetin | Resveratrol | Streptozocin | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 1 gene: PARP1 237
21. lipid oxidation Obesity Inferred via 32 chemicals: 4-hydroxy-2-nonenal | Acetylcysteine | Ascorbic Acid | bisphenol A | Chlorpyrifos | Cholesterol, Dietary | cobaltiprotoporphyrin | Curcumin | Cyclosporine | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Enalapril | Fatty Acids, Nonesterified | Fluoxetine | Folic Acid | Fructose | Glutathione | Lead | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | Panax notoginseng extract | Particulate Matter | Plant Extracts | Poloxamer | Prednisolone | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Vehicle Emissions | Water Pollutants, Chemical   271
22. detection of oxidative stress Obesity Inferred via 31 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | Clozapine | Curcumin | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Enalapril | Ephedrine | Fructose | Lead | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | Nicotine | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Sucrose | Telmisartan | Valproic Acid | Vehicle Emissions | Water Pollutants, Chemical Inferred via 1 gene: ADIPOQ 190
23. reactive oxygen species metabolic process Obesity Inferred via 29 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 4-hydroxy-2-nonenal | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Capsaicin | Chlorpyrifos | cobaltiprotoporphyrin | Curcumin | DDT | Diethylnitrosamine | Diethylstilbestrol | Fatty Acids, Nonesterified | Fructose | Glutathione | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | NAD | naringenin | Nicotine | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Vehicle Emissions Inferred via 2 genes: SOD1 | SOD2 186
24. mitotic cell cycle arrest Obesity Inferred via 28 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | C646 compound | Cadmium | Calcifediol | Chlorpyrifos | Curcumin | deoxynivalenol | Estrogens | Folic Acid | glabridin | Glutathione | Halogenated Diphenyl Ethers | Metformin | naringenin | Nicotine | Oleanolic Acid | Panax notoginseng extract | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Valproic Acid   142
25. negative regulation of cell proliferation Obesity Inferred via 27 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Chlorpyrifos | Curcumin | Cyclosporine | DDT | deoxynivalenol | Dichlorodiphenyl Dichloroethylene | Diethylstilbestrol | Fluoxetine | Glutathione | Metformin | Methoxychlor | NAD | Nicotine | Oleanolic Acid | Particulate Matter | Plant Extracts | Prednisone | Quercetin | Resveratrol | Rosiglitazone | Sertraline | Valproic Acid Inferred via 10 genes: BCHE | CEBPA | CYP1B1 | HMOX1 | IL6 | MIR21 | PPARG | PTGS2 | SOD2 | TNF 146
26. vasodilation Obesity Inferred via 27 chemicals: Acetylcysteine | AVE 7688 | Barium | Caffeine | Canrenoic Acid | Capsaicin | Cromolyn Sodium | Cyclosporine | Dietary Carbohydrates | Dietary Fats | Enalapril | Fructose | Glutathione | Glutathione Disulfide | Hydrocortisone | Metformin | Nicotine | Particulate Matter | Quercetin | Resveratrol | Rosiglitazone | Sertraline | Streptozocin | Telmisartan | Topiramate | Vehicle Emissions | Yohimbine Inferred via 5 genes: APOE | GPX1 | KCNMA1 | SOD2 | TNF 192
27. lipid biosynthetic process Obesity Inferred via 26 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Bezafibrate | bisphenol A | Caffeine | Clozapine | cobaltiprotoporphyrin | Curcumin | Cyclosporine | Dietary Fats | Dihydrotestosterone | Estrogens | Fluoxetine | Fructose | Hydrocortisone | Manganese | Orlistat | Phthalic Acids | Plant Extracts | pregna-4,17-diene-3,16-dione | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Sucrose | Topiramate | Valproic Acid Inferred via 8 genes: ACLY | ACSL1 | CNR1 | FASN | GCG | INS | SCD1 | SREBF1 225
28. cholesterol homeostasis Obesity Inferred via 26 chemicals: Acetylcysteine | Anticholesteremic Agents | Ascorbic Acid | bisphenol A | Calcifediol | Cholesterol, Dietary | Chromium | Curcumin | deoxynivalenol | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Enalapril | Folic Acid | Fructose | Manganese | Mercury | Metformin | Nicotine | Particulate Matter | Plant Extracts | Poloxamer | Quercetin | Resveratrol | Streptozocin | trans-3-(4'-hydroxyphenyl)-2-propenoic acid Inferred via 7 genes: AKT1 | APOE | LDLR | LPL | MIR34A | NPC1 | SIRT1 164
29. regulation of heart rate Obesity Inferred via 26 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | Bezafibrate | Caffeine | Capsaicin | Clozapine | Cyclosporine | Enalapril | Ephedrine | Fluoxetine | Hydrocortisone | Lead | Lithium | Mazindol | Mercury | Mianserin | NAD | Nicotine | Particulate Matter | Plant Extracts | sibutramine | Streptozocin | Telmisartan | Topiramate | Trazodone | Yohimbine Inferred via 2 genes: ADRB1 | PMCH 152
30. vasoconstriction Obesity Inferred via 26 chemicals: Acetylcysteine | AVE 7688 | Cadmium | Caffeine | Canrenoic Acid | Capsaicin | Cobalt | Curcumin | Cyclosporine | Dietary Carbohydrates | Dietary Fats | Enalapril | Fluoxetine | Fructose | Hydrocortisone | Nicotine | Particulate Matter | Plant Extracts | Prednisolone | Quercetin | Rosiglitazone | Sertraline | Streptozocin | Telmisartan | Vehicle Emissions | Yohimbine   192
31. glucose homeostasis Obesity Inferred via 25 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetylcysteine | bisphenol A | Cadmium | Cobalt | cobaltiprotoporphyrin | Curcumin | DDT | Dietary Carbohydrates | Dietary Fats | Diethylnitrosamine | Enalapril | Estrogens | Folic Acid | Fructose | Lead | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercury | Metformin | Panax notoginseng extract | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Streptozocin Inferred via 15 genes: ADIPOQ | AKT1 | CEBPA | CNR1 | FOXO3 | IL6 | INS | IRS1 | LEP | LEPR | PCK1 | PMCH | POMC | PPARG | SERPINE1 201
32. nitric oxide biosynthetic process Obesity Inferred via 25 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Capsaicin | Chlorpyrifos | Curcumin | Cyclosporine | Dietary Fats | Diethylnitrosamine | Fructose | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | naringenin | Particulate Matter | Pioglitazone | Plant Extracts | Quercetin | Resveratrol | sibutramine | Streptozocin | Telmisartan Inferred via 3 genes: AKT1 | CYP1B1 | NQO1 225
33. positive regulation of mitochondrial membrane potential Obesity Inferred via 25 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | Curcumin | Cyclosporine | Dichlorodiphenyl Dichloroethylene | Diethylhexyl Phthalate | Glutathione | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | Orlistat | Particulate Matter | Pioglitazone | Plant Extracts | Quercetin | Resveratrol | Rimonabant | Thallium | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid Inferred via 1 gene: AKT1 134
34. apoptotic DNA fragmentation Obesity Inferred via 25 chemicals: Acetylcysteine | Ascorbic Acid | Cadmium | Caffeine | Capsaicin | Curcumin | Cyclosporine | Enalapril | Fenretinide | Fluoxetine | Hydrocortisone | Lithium | manganese(III)-tetrakis(4-benzoic acid)porphyrin | naringenin | Nicotine | Particulate Matter | Plant Extracts | Prednisolone | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Telmisartan | Valproic Acid | Vehicle Emissions Inferred via 1 gene: HMGB2 134
35. triglyceride homeostasis Obesity Inferred via 24 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Anticholesteremic Agents | Ascorbic Acid | bisphenol A | Cadmium | Calcifediol | Cholesterol, Dietary | Chromium | Curcumin | deoxynivalenol | Dietary Carbohydrates | Dietary Fats | Dietary Sucrose | Folic Acid | Fructose | GW 4064 | Metformin | Nicotine | Plant Extracts | Poloxamer | Quercetin | Resveratrol | Streptozocin | trans-3-(4'-hydroxyphenyl)-2-propenoic acid Inferred via 5 genes: ANGPTL4 | APOE | LPL | MIR34A | PPARG 155
36. cell cycle Obesity Inferred via 24 chemicals: Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Capsaicin | Curcumin | Cyclosporine | Diethylstilbestrol | Dihydrotestosterone | Estrogens | Glutathione | Lithium | Naproxen | Nicotine | Orlistat | Plant Extracts | Prednisolone | Resveratrol | Rimonabant | Rosiglitazone | Streptozocin | Valproic Acid Inferred via 3 genes: AHR | DDIT3 | EP300 163
37. positive regulation of p38MAPK cascade Obesity Inferred via 23 chemicals: 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide | 4-hydroxy-2-nonenal | Acetylcysteine | alpha-naphthoflavone | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | cobaltiprotoporphyrin | Curcumin | Dietary Fats | Folic Acid | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Methoxychlor | naringenin | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Valproic Acid | Vehicle Emissions Inferred via 1 gene: LEP 189
38. protein oxidation Obesity Inferred via 23 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Cholesterol, Dietary | Curcumin | Dietary Fats | Diethylnitrosamine | Folic Acid | Glutathione | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | naringenin | Particulate Matter | Plant Extracts | Prednisolone | Quercetin | Resveratrol | Streptozocin | Vehicle Emissions Inferred via 1 gene: GPX1 179
39. positive regulation of superoxide dismutase activity Obesity Inferred via 22 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Chlorpyrifos | Cobalt | Curcumin | Cyclosporine | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Dihydrotestosterone | Fatty Acids, Nonesterified | Fluoxetine | Folic Acid | Fructose | Glutathione | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Panax notoginseng extract | Plant Extracts | Quercetin | Resveratrol | Streptozocin | Water Pollutants, Chemical Inferred via 1 gene: TNF 202
40. L-aspartate:2-oxoglutarate aminotransferase activity Obesity Inferred via 22 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Curcumin | Cyclosporine | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Fructose | herbacetin | Lead | Metformin | naringenin | Orlistat | Pioglitazone | pirinixic acid | Plant Extracts | Poloxamer | Quercetin | Resveratrol | Streptozocin   202
41. leukocyte migration involved in inflammatory response Obesity Inferred via 22 chemicals: 2-chloroethyl ethyl sulfide | Acetylcysteine | bisphenol A | Caffeine | Cromolyn Sodium | Curcumin | Cyclosporine | Dietary Carbohydrates | Dietary Fats | Diethylnitrosamine | Fructose | Metformin | Oleanolic Acid | Particulate Matter | Pioglitazone | Plant Extracts | Prednisolone | Quercetin | Resveratrol | Streptozocin | Telmisartan | Vehicle Emissions   171
42. positive regulation of multicellular organism growth Obesity Inferred via 21 chemicals: Acetylcysteine | bisphenol A | Caffeine | Canrenoic Acid | Chlorpyrifos | deoxynivalenol | Dietary Fats | Diethylnitrosamine | Fluoxetine | Lead | Manganese | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Margarine | Metformin | Nicotine | Plant Extracts | Resveratrol | Streptozocin | Valproic Acid | Water Pollutants, Chemical | Yohimbine Inferred via 3 genes: GH1 | GHRL | IGF2 151
43. lactate dehydrogenase activity Obesity Inferred via 21 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Caffeine | Chlorpyrifos | Clozapine | cobaltiprotoporphyrin | Curcumin | Dichlorodiphenyl Dichloroethylene | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Folic Acid | Metformin | NAD | Plant Extracts | Quercetin | Resveratrol | Streptozocin   162
44. alkaline phosphatase activity Obesity Inferred via 21 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Curcumin | Cyclosporine | Dietary Carbohydrates | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Firemaster 550 | Fructose | Halogenated Diphenyl Ethers | Lead | Metformin | naringenin | Pioglitazone | Plant Extracts | Quercetin | Resveratrol | Streptozocin | Telmisartan   157
45. spermatogenesis Obesity Inferred via 20 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | Cyclosporine | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylstilbestrol | Fluoxetine | Glutathione | mono(2-ethyl-5-hydroxyhexyl) phthalate | mono(2-ethyl-5-oxohexyl)phthalate | Olanzapine | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Water Pollutants, Chemical Inferred via 7 genes: AQP7 | CNR1 | CYP26B1 | HMGB2 | PMCH | SIRT1 | SOD1 157
46. hydrogen peroxide biosynthetic process Obesity Inferred via 20 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Cadmium | Chlorpyrifos | Cholesterol, Dietary | Curcumin | Cyclosporine | Dietary Fats | Glutathione | Manganese | Mercury | Metformin | NAD | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Streptozocin | Water Pollutants, Chemical Inferred via 2 genes: SOD1 | SOD2 166
47. positive regulation of glutathione peroxidase activity Obesity Inferred via 20 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Cobalt | Curcumin | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylnitrosamine | Dihydrotestosterone | Environmental Pollutants | Folic Acid | Glutathione | Mercury | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Thallium | Water Pollutants, Chemical   165
48. cell growth Obesity Inferred via 20 chemicals: 4-hydroxy-2-nonenal | Acetylcysteine | Ascorbic Acid | bisphenol A | Capsaicin | Chlorpyrifos | Cyclosporine | deoxynivalenol | Fluoxetine | Folic Acid | Glutathione | Hydrocortisone | manganese(III)-tetrakis(4-benzoic acid)porphyrin | naringenin | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | trans-3-(4'-hydroxyphenyl)-2-propenoic acid | Valproic Acid   97
49. positive regulation of nitric oxide biosynthetic process Obesity Inferred via 19 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | cobaltiprotoporphyrin | Curcumin | Cyclosporine | Dietary Fats | evodiamine | Fructose | Manganese | Metformin | Plant Extracts | Poloxamer | Prednisolone | Quercetin | Resveratrol | Rosiglitazone | Sertraline | Streptozocin Inferred via 9 genes: AKT1 | CRP | ESR1 | ICAM1 | IL6 | PTGS2 | SOD2 | TNF | TRPV1 178
50. superoxide anion generation Obesity Inferred via 19 chemicals: Acetylcysteine | Ascorbic Acid | bisphenol A | Curcumin | Cyclosporine | Dietary Fats | Diethylstilbestrol | Halogenated Diphenyl Ethers | Lead | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Oleanolic Acid | Particulate Matter | Plant Extracts | Quercetin | Resveratrol | Rosiglitazone | Streptozocin | Valproic Acid | Vehicle Emissions Inferred via 2 genes: SOD1 | SOD2 160
1–50 of 7,556 results.