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Disease Chemical and Drug Induced Liver Injury

These phenotypes are associated with Chemical and Drug Induced Liver Injury or its descendants. A phenotype has an inferred association via a curated chemical interaction or a gene-GO annotation or both.

1–50 of 7,322 results.
  Phenotype Disease Chemical Inference Network Gene Inference Network References
1. cell proliferation Chemical and Drug Induced Liver Injury Inferred via 506 chemicals: 1,2,4-triazole | 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole | 1,2-Dimethylhydrazine | 1,3-dichloro-2-propanol | 1-(4-(1-((E)-4-cyclohexyl-3-trifluoromethylbenzyloxyimino)-ethyl)-2-ethylbenzyl)-azetidine-3-carboxylic acid | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 16,16-Dimethylprostaglandin E2 | 18alpha-glycyrrhetinic acid | 1-Naphthylisothiocyanate | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,4-dichlorophenol | 2,4-Dinitrophenol | 2-Acetylaminofluorene | 3,4,5,3',4'-pentachlorobiphenyl | 3-amino-1-methyl-5H-pyrido(4,3-b)indole | 3-methylquercetin | 4,4'-hexafluorisopropylidene diphenol | 4-biphenylamine | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 4-nitrophenol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-phenylbutyric acid | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 6-methyl-2-(phenylethynyl)pyridine | 9,10-Dimethyl-1,2-benzanthracene | A 771726 | Acetaminophen | Acetylcysteine | acifluorfen | Acitretin | Acrolein | Adenosine Triphosphate | ado-trastuzumab emtansine | Adrenal Cortex Hormones | Aflatoxin B1 | Albendazole | Alcohols | Alendronate | Alitretinoin | allicin | Allopurinol | allyl isothiocyanate | allyl sulfide | alpha-naphthoflavone | alpha-Tocopherol | Alprazolam | Alprostadil | Aluminum Chloride | Aluminum Oxide | Amino Acids, Peptides, and Proteins | Amiodarone | Amitriptyline | Amlodipine | Amodiaquine | Amphotericin B | amphotericin B, deoxycholate drug combination | Androgens | andrographolide | Apigenin | Arecoline | Arsenic | arsenic disulfide | Arsenic Trioxide | arsenite | Artesunate | Ascorbic Acid | Aspirin | Astemizole | astin B | Atenolol | Atorvastatin | Atrazine | Atropine | Auranofin | Axitinib | Azacitidine | Azoxymethane | baicalein | benoxaprofen | Benzbromarone | Benzene | Benzo(a)pyrene | Berberine | beta Carotene | Betaine | bicalutamide | Bile Acids and Salts | Bilirubin | Biliverdine | bisphenol A | boric acid | Bortezomib | Bosentan | Budesonide | Buprenorphine | Busulfan | Buthionine Sulfoximine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caffeic acid | candesartan | Canertinib | Capsaicin | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Carboplatin | Carmustine | Carnitine | Carvedilol | Catechin | Celecoxib | ceric oxide | cerivastatin | cerous chloride | chelerythrine | Chenodeoxycholic Acid | chloroacetaldehyde | Chlorodiphenyl (54% Chlorine) | Chlorogenic Acid | Chloroquine | Chlorpromazine | Chlorpyrifos | Cholesterol | Cholic Acid | chromium hexavalent ion | Cimetidine | ciprofibrate | Ciprofloxacin | Cisplatin | Citalopram | Clodronic Acid | Clofibrate | Clotrimazole | Clozapine | cobaltous chloride | Cocaine | coenzyme Q10 | Colchicine | Copper | Copper Sulfate | corosolic acid | Crizotinib | cucurbitacin E | cumene hydroperoxide | cupric chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclophosphamide | Cyclosporine | cylindrospermopsin | cyproconazole | Cyproheptadine | Cyproterone Acetate | Cytarabine | Dactinomycin | Dantrolene | Dasatinib | Daunorubicin | DDT | decabromobiphenyl ether | decamethrin | Deferoxamine | Deoxycholic Acid | deoxynivalenol | Desflurane | Desipramine | Dexamethasone | diallyl disulfide | diallyl trisulfide | Diazinon | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dieldrin | Dietary Fats | Diethylhexyl Phthalate | diethyl maleate | Diethylnitrosamine | diethyl phthalate | Diethylstilbestrol | dihydromyricetin | Diltiazem | Dimethyl Sulfoxide | dioscin | Diosmin | Diphenhydramine | Dipyridamole | Diquat | Disulfiram | Ditiocarb | Docetaxel | Donepezil | Doxorubicin | Drugs, Chinese Herbal | Dust | efavirenz | Emodin | Enalapril | Endosulfan | epigallocatechin gallate | Erlotinib Hydrochloride | Estradiol | Ethanol | Ethinyl Estradiol | Etoposide | Eugenol | Fenbendazole | fialuridine | Fish Oils | Flame Retardants | Flavonoids | Fluorouracil | Fluoxetine | Flurbiprofen | Flutamide | Fluvastatin | Folic Acid | folpet | Formaldehyde | Fructose | fumonisin B1 | Fungal Polysaccharides | furan | Furazolidone | Furosemide | gadolinium chloride | Galactosamine | Gefitinib | Genistein | Gliotoxin | Glucocorticoids | Glutathione | Glycyrrhizic Acid | glyphosate | Grape Seed Extract | Griseofulvin | Halogenated Diphenyl Ethers | Halothane | Harmine | Hemin | Heparin | hesperetin | Hesperidin | hexabromocyclododecane | Histamine | Hydralazine | Hydrocarbons, Chlorinated | Hydrogen Peroxide | hydroquinone | Hydroxyapatites | hydroxyflutamide | Hydroxyurea | hyperoside | Ibuprofen | Imatinib Mesylate | imidacloprid | Imipramine | imperatorin | Indoles | Indomethacin | Irinotecan | Iron | Isoflurane | Isotretinoin | Itraconazole | Ketoconazole | Lansoprazole | lanthanum oxide | Lapatinib | Lead | lead acetate | lead nitrate | Leflunomide | Lipids | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lithium | lonidamine | Lopinavir | Losartan | Lovastatin | lumiracoxib | Lutein | Lycopene | magnolol | Malathion | Maneb | manganese chloride | mangiferin | manumycin | Maprotiline | Mebendazole | Medroxyprogesterone Acetate | Melatonin | Meloxicam | Melphalan | Mequindox | Mercaptopurine | Mercuric Chloride | Mercury | Mesna | Metformin | Methamphetamine | Methapyrilene | Methimazole | Methionine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Mibefradil | microcystin | Mifepristone | Minocycline | mithramycin A | Mitotane | Monocrotaline | Monocrotophos | morin | Morphine | Mycophenolic Acid | myricitrin | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | N-acetyl-4-benzoquinoneimine | Naltrexone | Nandrolone Decanoate | Nanotubes, Carbon | naringenin | naringin | necrostatin-1 | nefazodone | Nelfinavir | Nevirapine | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nicotine | Nifedipine | Niflumic Acid | nimesulide | Nimodipine | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | ochratoxin A | Octreotide | Ofloxacin | Olanzapine | Oleanolic Acid | Omeprazole | Orlistat | Oxaliplatin | Oxygen | oxymatrine | Ozone | Paclitaxel | Paraquat | Paroxetine | Particulate Matter | Penicillamine | Pentoxifylline | perfluorododecanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Permethrin | phenanthrene | Phenobarbital | Phentolamine | Phenylbutazone | Phenytoin | Phloretin | Phytochemicals | pimagedine | Pioglitazone | piperine | Piperonyl Butoxide | pirinixic acid | Plant Extracts | Plant Preparations | Polyethylene Glycols | Polylactic Acid-Polyglycolic Acid Copolymer | Polysaccharides | potassium bromate | potassium chromate(VI) | Potassium Dichromate | Prazosin | Prednisolone | Pregabalin | Pregnenolone Carbonitrile | Proadifen | Probenecid | Progesterone | propiconazole | Propolis | Propranolol | Propylthiouracil | puag-haad | Putrescine | Pyrazinamide | pyrazolanthrone | pyrene | Pyrogallol | Pyruvaldehyde | Quercetin | Quinacrine | Quinidine | Raloxifene Hydrochloride | Ramipril | Ranitidine | Reactive Oxygen Species | Reserpine | Resveratrol | Ribavirin | Rifampin | Risedronic Acid | Ritonavir | rofecoxib | Rosiglitazone | Rotenone | Rutin | S-Adenosylmethionine | saikosaponin | salvianolic acid B | Saponins | Saquinavir | SB 203580 | sesamin | sesamol | Sevoflurane | Silver | Silybin | Silymarin | Simvastatin | Smoke | sodium arsenate | sodium arsenite | Sodium Cholate | Sodium Fluoride | Sodium Selenite | Sorafenib | Spermidine | Spironolactone | SRT1720 | Streptozocin | Sulfasalazine | sulforafan | Sulindac | Tacrolimus | Tamoxifen | tangeretin | Tapentadol | Taurine | Taurochenodeoxycholic Acid | Taurocholic Acid | Taurolithocholic Acid | tauroursodeoxycholic acid | Temozolomide | Terfenadine | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | tetrahydrocurcumin | tetrathiomolybdate | Thalidomide | theaflavin | Thioacetamide | Thioctic Acid | thymoquinone | Tiopronin | titanium dioxide | Tolbutamide | Tretinoin | Trichloroethylene | Triiodothyronine | tri-o-cresyl phosphate | triphenyl phosphate | tris(1,3-dichloro-2-propyl)phosphate | tris(2,3-dibromopropyl)isocyanurate | Troglitazone | U 0126 | Ursodeoxycholic Acid | ursolic acid | usnic acid | Valproic Acid | Vehicle Emissions | Verapamil | Vincristine | Vitamin A | Vitamin E | Vitamin K 3 | Warfarin | Zearalenone | zileuton | Zinc | zinc chloride | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate | Zoledronic Acid Inferred via 12 genes: BAX | CHRM3 | CTNNB1 | CXCL1 | IGF1 | IL18 | IL1A | PARK7 | PRKDC | SORL1 | TNF | VEGFA 3998
2. apoptotic process Chemical and Drug Induced Liver Injury Inferred via 493 chemicals: 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole | 1,2-Dimethylhydrazine | 1,3-dichloro-2-propanol | 16,16-Dimethylprostaglandin E2 | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,3-dimethoxy-1,4-naphthoquinone | 2,4-dichlorophenol | 2-Acetylaminofluorene | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | 3-methylquercetin | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-phenylbutyric acid | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | A 771726 | Acetaminophen | Acetylcysteine | Acitretin | Acrolein | Adenosine Triphosphate | Aflatoxin B1 | Aldosterone | Alendronate | alisol B 23-acetate | Alitretinoin | Allopurinol | alpha-Linolenic Acid | alpha-naphthoflavone | alpha-Tocopherol | Alprazolam | Alprostadil | Aluminum Chloride | Amino Acids, Peptides, and Proteins | Amiodarone | Amitriptyline | Amlodipine | Amoxicillin | Amsacrine | andrographolide | anethole | Angiotensin-Converting Enzyme Inhibitors | Apigenin | Arecoline | Arsenic | arsenic disulfide | Arsenic Trioxide | arsenite | Artesunate | Ascorbic Acid | Aspirin | Astemizole | astin B | Atenolol | Atorvastatin | Atrazine | Atropine | Auranofin | Axitinib | Azacitidine | Azoxymethane | baicalein | Benzo(a)pyrene | Berberine | beta Carotene | Betaine | Bezafibrate | bicalutamide | Bilirubin | bisphenol A | Bortezomib | Bosentan | Bromocriptine | Budesonide | Buthionine Sulfoximine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caffeic acid | candesartan | Canertinib | Capsaicin | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Carboplatin | Carmustine | Carnitine | Carvedilol | Catechin | Celecoxib | Cephalothin | ceric oxide | cerivastatin | cerous chloride | chelerythrine | Chenodeoxycholic Acid | Chlorambucil | Chloramphenicol | Chlormethiazole | chloroacetaldehyde | Chloroquine | Chlorpromazine | Chlorpyrifos | Cholesterol | Cholic Acid | Choline | Chromium | chromium hexavalent ion | Cimetidine | cinnabar | Ciprofloxacin | Cisplatin | Citalopram | Clarithromycin | Clodronic Acid | Clofibrate | Clotrimazole | Clozapine | cobaltous chloride | Cocaine | coenzyme Q10 | Colchicine | Copper | Copper Sulfate | corosolic acid | Creatine | cucurbitacin E | cupric chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclophosphamide | Cyclosporine | Cytarabine | Dacarbazine | Dactinomycin | Danazol | Dantrolene | Dasatinib | Daunorubicin | DDT | decabromobiphenyl ether | decamethrin | Deferoxamine | Deoxycholic Acid | deoxynivalenol | Desipramine | Dexamethasone | Dexmedetomidine | diallyl disulfide | diallyl trisulfide | Diatrizoate Meglumine | Diazinon | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | diethyl maleate | Diethylnitrosamine | Diethylstilbestrol | Digoxin | dihydromyricetin | Diltiazem | Dimethylnitrosamine | Dimethyl Sulfoxide | Diosmin | Diphenhydramine | Dipyridamole | Diquat | Disulfiram | Ditiocarb | Docetaxel | Donepezil | Doxorubicin | Doxycycline | Drugs, Chinese Herbal | ebselen | Emodin | Enalapril | Endosulfan | epigallocatechin gallate | Epirubicin | erdosteine | Erlotinib Hydrochloride | Estradiol | Estramustine | Ethanol | Ethinyl Estradiol | Etoposide | Fatty Acids | Fenofibrate | Fish Oils | Flavonoids | Floxuridine | Fluorouracil | Fluoxetine | flupirtine | Flutamide | Folic Acid | Formaldehyde | formylchromone | Fosinopril | Fructose | fumonisin B1 | Furazolidone | Galactosamine | Gefitinib | Genistein | germacrone | Gliclazide | Gliotoxin | Glucocorticoids | Glutathione | Glyburide | glycine propionyl carnitine | Glycochenodeoxycholic Acid | Glycodeoxycholic Acid | Glycyrrhizic Acid | Grape Seed Extract | Haloperidol | Halothane | Hemin | Heparin | hesperetin | hexabromocyclododecane | Hexachlorocyclohexane | Histamine | Hyaluronic Acid | Hydralazine | Hydrogen Peroxide | hydroquinone | Hydroxyapatites | Hydroxyurea | Ibuprofen | Imatinib Mesylate | Imipramine | Indinavir | Indoles | Indomethacin | Irbesartan | Irinotecan | Iron | Isoflurane | isoliquiritigenin | Isoniazid | Isotretinoin | Ketoconazole | Lansoprazole | Lapatinib | Lead | lead acetate | lead nitrate | Leflunomide | Leucovorin | Levofloxacin | Limonene | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lisinopril | Lithium | Losartan | Lovastatin | lumiracoxib | Lutein | Lycopene | Magnesium Oxide | magnolol | Malathion | Malondialdehyde | Maneb | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | manumycin | Maprotiline | Mebendazole | Medroxyprogesterone Acetate | Melatonin | Meloxicam | Melphalan | Memantine | Mercaptopurine | Mercuric Chloride | Mercury | Mesalamine | Metformin | Methamphetamine | Methapyrilene | Methimazole | Methionine | Methotrexate | methyleugenol | methylmercuric chloride | Methylmercury Compounds | Methylprednisolone | Metyrapone | microcystin | Mifepristone | Minocycline | mithramycin A | Mitotane | MitoTEMPO | montelukast | Morphine | Mycophenolic Acid | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | N-acetyl-4-benzoquinoneimine | NAD | Naltrexone | Nandrolone Decanoate | Nanotubes, Carbon | Naproxen | naringin | Nelfinavir | Niacin | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nicotine | Nifedipine | Niflumic Acid | nimesulide | Nimodipine | Nitric Oxide | NOC 18 | nodularin | Nortriptyline | obeticholic acid | ochratoxin A | Octreotide | Ofloxacin | Olanzapine | Oleanolic Acid | olmesartan | Omeprazole | Orlistat | Oxaliplatin | Oxaprozin | Oxygen | Ozone | Paclitaxel | paeonol | Palmitates | Paraquat | Paroxetine | Particulate Matter | Penicillamine | Pentoxifylline | Peptides | perfluorooctane sulfonic acid | perfluorooctanoic acid | Perindopril | Phenobarbital | phenyl-N-tert-butylnitrone | Phenytoin | Phytochemicals | pimagedine | Pioglitazone | pirinixic acid | Piroxicam | Plant Extracts | Plant Preparations | Poloxamer | Polyphenols | Polysaccharides | potassium bromate | Potassium Dichromate | Pravastatin | Prazosin | Prednisolone | Progesterone | Propofol | Propolis | Propranolol | Propylthiouracil | puerarin | Putrescine | Pyrazinamide | pyrazolanthrone | Pyrogallol | Pyruvaldehyde | Quercetin | Quetiapine Fumarate | Quinacrine | Quinidine | Raloxifene Hydrochloride | Ramipril | Ranitidine | Reactive Oxygen Species | Reserpine | Resveratrol | Ribavirin | Rifampin | Risedronic Acid | Ritonavir | rofecoxib | Rosiglitazone | Rotenone | Roxithromycin | Rutin | S-Adenosylmethionine | safingol | Salicylates | Salicylic Acid | salvianolic acid B | Saponins | Saquinavir | SB 203580 | Scopolamine | Selenium | senecionine | Sertraline | sesamin | sesamol | Sevoflurane | Silver | Silybin | Silymarin | Simvastatin | Smoke | S-Nitroso-N-Acetylpenicillamine | sodium arsenite | Sodium Fluoride | Sodium Selenite | Sorafenib | Spermidine | Spironolactone | SRT1720 | Stavudine | Streptozocin | Sulfasalazine | sulforafan | Sulindac | Tacrine | Tacrolimus | Tamoxifen | Taurocholic Acid | Taurolithocholic Acid | tauroursodeoxycholic acid | Tea | Telmisartan | Temozolomide | TEMPO | Terfenadine | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thalidomide | theaflavin | Thiamethoxam | Thioacetamide | Thioctic Acid | Thioguanine | thymoquinone | Ticlopidine | Tiopronin | titanium dioxide | Tolbutamide | Tramadol | Tretinoin | tributyrin | Triiodothyronine | triptolide | tris(1,3-dichloro-2-propyl)phosphate | tris(2,3-dibromopropyl)isocyanurate | Troglitazone | troxerutin | U 0126 | uranyl acetate | Uridine | Ursodeoxycholic Acid | ursolic acid | Valproic Acid | Vehicle Emissions | Venlafaxine Hydrochloride | Verapamil | Vincristine | Vitamin A | Vitamin E | Vitamin K 3 | Warfarin | Zearalenone | Zidovudine | zileuton | Zinc | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate | Zoledronic Acid Inferred via 19 genes: AHR | AIFM1 | ATG5 | BAX | GADD45A | GSN | HMOX1 | IFNA2 | IFNG | IL17A | IL1A | IL1B | ITPR1 | LCN2 | MAP3K5 | POLR2G | TF | TGFBR1 | TNF 4812
3. cell death Chemical and Drug Induced Liver Injury Inferred via 398 chemicals: 1-aminobenzotriazole | 1-Naphthylisothiocyanate | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,4-Dinitrophenol | 2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester | 3',5'-dimethylacetaminophen | 3-methylquercetin | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 4-nitrophenol | 4-oxo-2-nonenal | 4-phenylbutyric acid | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 6-methyl-2-(phenylethynyl)pyridine | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | Adenosine Triphosphate | Aflatoxin B1 | Albendazole | Alitretinoin | Allopurinol | Alloxan | allyl alcohol | alpha-Linolenic Acid | alpha-naphthoflavone | alpha-Tocopherol | Aluminum | Aluminum Oxide | Amiodarone | Amitriptyline | Amlodipine | Amodiaquine | Amphotericin B | amphotericin B, deoxycholate drug combination | Amsacrine | Apigenin | Arsenic Trioxide | arsenite | Ascorbic Acid | Aspirin | Atorvastatin | Atropine | Auranofin | Azacitidine | Azathioprine | baicalein | Bentonite | Benzo(a)pyrene | beta Carotene | Bezafibrate | bisphenol A | Blood Glucose | Bortezomib | Bromocriptine | Bupropion | Busulfan | Buthionine Sulfoximine | Butylated Hydroxyanisole | Cadmium | Cadmium Chloride | caffeic acid | Capsaicin | Carbamazepine | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Carboplatin | Carmustine | Carnosine | Carvedilol | Catechin | Ceftriaxone | Celecoxib | ceric oxide | Chlorambucil | Chloramphenicol | Chlorogenic Acid | Chloroquine | Chlorpromazine | Chlorpyrifos | Chlorzoxazone | Cholesterol | Cimetidine | Cisplatin | clivorine | Clozapine | cobaltous chloride | Cocaine | Colchicine | Copper | Copper Sulfate | Creatine | cucurbitacin E | cumene hydroperoxide | cupric chloride | Curcumin | Cyanamide | Cycloheximide | Cyclosporine | cylindrospermopsin | Cystine | Cytarabine | Dacarbazine | Dactinomycin | Dantrolene | Dapsone | Dasatinib | Daunorubicin | decabromobiphenyl ether | decamethrin | Deferoxamine | deoxynivalenol | Desflurane | Desipramine | Dexamethasone | Dextromethorphan | diallyl trisulfide | Dichloroacetic Acid | Dichlorvos | Diclofenac | Dieldrin | Dietary Fats | diethyl maleate | Digoxin | Diltiazem | Dimethylformamide | Dipyridamole | Diquat | Disulfiram | Ditiocarb | Docetaxel | Doxorubicin | Doxycycline | Dronedarone | Drugs, Chinese Herbal | Dust | dysprosium oxide | Enalapril | Endosulfan | epigallocatechin gallate | Epirubicin | erbium oxide | Erlotinib Hydrochloride | Estradiol | Ethanol | Ethinyl Estradiol | Ethosuximide | Etoposide | Eugenol | Ezetimibe | ferric chloride | fialuridine | fipronil | Flame Retardants | Fluorouracil | Fluoxetine | Flutamide | Fluvastatin | Formaldehyde | fucoxanthin | fumonisin B1 | Furazolidone | Furosemide | gadolinium chloride | gadolinium oxide | Galactosamine | Gefitinib | Gemfibrozil | Genistein | Gliclazide | Gliotoxin | Glucocorticoids | Glutathione | Glyburide | Glycochenodeoxycholic Acid | Griseofulvin | Halogenated Diphenyl Ethers | Haloperidol | Harmine | Hemin | Heparin | hexabromocyclododecane | Hexachlorocyclohexane | Histamine | Hydralazine | Hydrochlorothiazide | Hydrogen Peroxide | hydroquinone | Hydroxyurea | hyperoside | Ibuprofen | Imatinib Mesylate | Imipramine | imperatorin | Indomethacin | Irinotecan | Iron | Isoflurane | Isoniazid | Itraconazole | Ketoconazole | Ketoprofen | lanthanum oxide | Lead | lead acetate | Leflunomide | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lithium | Losartan | Lovastatin | Lutein | Maneb | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Maprotiline | Mefloquine | Melatonin | Meloxicam | Melphalan | Memantine | Mercaptopurine | Mercuric Chloride | Mercury | Metformin | Methamphetamine | Methapyrilene | Methimazole | Methionine | Methotrexate | Methyldopa | methylmercuric chloride | Methylmercury Compounds | Methylprednisolone | Mibefradil | Mifepristone | Minocycline | Mitotane | morin | Morphine | Mycophenolic Acid | myricitrin | N-acetyl-4-benzoquinoneimine | NAD | Naltrexone | Nanotubes, Carbon | naringenin | naringin | necrostatin-1 | nefazodone | Nelfinavir | neodymium oxide | Nickel | nickel chloride | Nicotine | Nifedipine | nimesulide | Nimodipine | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | nodularin | Nortriptyline | ochratoxin A | Octreotide | Ofloxacin | Oleanolic Acid | oltipraz | Omeprazole | Orlistat | Oxaliplatin | Oxygen | Ozone | Paclitaxel | paeonol | Palmitates | Paraquat | Particulate Matter | pazopanib | Penicillamine | Pentamidine | Pentoxifylline | perfluorooctane sulfonic acid | perfluorooctanoic acid | Permethrin | Phenelzine | Phenobarbital | Phenytoin | pimagedine | pirinixic acid | Piroxicam | Plant Extracts | Plant Oils | Polyethylene Glycols | Polylactic Acid-Polyglycolic Acid Copolymer | Polymyxin B | potassium bromate | Potassium Dichromate | Proadifen | Probenecid | Progesterone | Propranolol | Putrescine | pyrazolanthrone | pyrazole | pyrazolone | Pyruvaldehyde | Quercetin | Quinacrine | Quinidine | Quinine | Raloxifene Hydrochloride | Reactive Oxygen Species | Reserpine | Resveratrol | retrorsine | Ribavirin | Rifampin | Ritonavir | Rivastigmine | rofecoxib | Rosiglitazone | Rotenone | Rutin | Salicylic Acid | salvianolic acid B | samarium oxide | Saponins | SB 203580 | schizandrin B | Selenium | Sevoflurane | Silver | Silybin | Simvastatin | Smoke | S-Nitroso-N-Acetylpenicillamine | sodium arsenate | sodium arsenite | Sodium Fluoride | Sodium Selenite | sodium tetrasulfide | Sorafenib | SRT1720 | Streptozocin | sulforafan | Sulindac | Tacrolimus | Tamoxifen | tangeretin | Tapentadol | Taurine | tauroursodeoxycholic acid | Temozolomide | Tenofovir | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | Thalidomide | Thiabendazole | Thiamethoxam | Thioacetamide | Thioctic Acid | thymoquinone | titanium dioxide | Tolbutamide | Tolmetin | toosendanin | Tramadol | Tretinoin | Trichloroethylene | Trinitrotoluene | triphenyl phosphate | triptolide | tris(1,3-dichloro-2-propyl)phosphate | Troglitazone | trovafloxacin | U 0126 | Ursodeoxycholic Acid | ursolic acid | usnic acid | Valproic Acid | Vehicle Emissions | Verapamil | Vincristine | Vitamin A | Vitamin E | Vitamin K 3 | Warfarin | Zearalenone | Zidovudine | Zinc | zinc chloride | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate Inferred via 2 genes: HMOX1 | IL17A 2686
4. lipid catabolic process Chemical and Drug Induced Liver Injury Inferred via 301 chemicals: 1,2,4-triazole | 1,2-Dimethylhydrazine | 18alpha-glycyrrhetinic acid | 1-bromopropane | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 3,4,5,3',4'-pentachlorobiphenyl | 3-Hydroxybutyric Acid | 3-methylquercetin | 4-nitrophenol | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 6-methyl-2-(phenylethynyl)pyridine | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetone | Acetylcysteine | Acrylamide | Acrylonitrile | Adenosine Triphosphate | Aflatoxin B1 | Alcohols | Alloxan | allyl isothiocyanate | allyl methyl disulfide | alpha-Linolenic Acid | alpha-Tocopherol | Alprostadil | Aluminum | Aluminum Chloride | Amiodarone | Apigenin | Arsenic | Arsenic Trioxide | arsenite | Artesunate | Ascorbic Acid | Aspirin | Atenolol | Atorvastatin | Atrazine | Auranofin | Bentonite | Benzo(a)pyrene | Berberine | Betaine | bifendate | Bilirubin | bisphenol A | bromobenzene | Bromocriptine | Buprenorphine | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caffeic acid | canadine | Carbon Tetrachloride | Carnitine | Carvedilol | Catechin | Charcoal | Chlormethiazole | Chlorodiphenyl (54% Chlorine) | Chlorogenic Acid | Chloroquine | chloroquine diphosphate | Chlorpyrifos | Cholesterol | Cholesterol, Dietary | Choline | chromium hexavalent ion | Cimetidine | Ciprofloxacin | Cisplatin | Clofibrate | cobaltous chloride | Cocaine | coenzyme Q10 | Copper | Copper Sulfate | cumene hydroperoxide | cupric chloride | Curcumin | Cyanamide | cyanoginosin LR | Cyclophosphamide | Cyclosporine | Cysteamine | decabromobiphenyl ether | decamethrin | deoxynivalenol | Dexamethasone | diallyl disulfide | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | dihydromyricetin | diisononyl phthalate | Dimethoate | dimethyl mercury | Dimethylnitrosamine | dioscin | diphenyldiselenide | Diquat | Ditiocarb | Donepezil | Doxorubicin | Doxycycline | Drugs, Chinese Herbal | ebselen | eleostearic acid | Enalapril | Endosulfan | Ephedrine | epigallocatechin gallate | Ethambutol | Ethanol | Ethinyl Estradiol | Ethylene Glycol | Famotidine | ferric chloride | fipronil | Flavonoids | Fluorouracil | Fomepizole | Formaldehyde | Fructose | fumonisin B1 | Fungal Polysaccharides | Galactosamine | Gemfibrozil | Genistein | Glutathione | Glyburide | glycine propionyl carnitine | Grape Seed Extract | Grape Seed Proanthocyanidins | Griseofulvin | Halothane | Hemin | Heparin | hesperetin | Hesperidin | Hyaluronic Acid | Hydrogen Peroxide | Hydroxyapatites | hyperoside | Imatinib Mesylate | imidacloprid | Indomethacin | Irinotecan | Iron | Iron-Dextran Complex | Isoniazid | Lansoprazole | lead acetate | lead chloride | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Losartan | Lovastatin | Lutein | Lycopene | Malathion | manganese chloride | mangiferin | Melatonin | Mequindox | Mercuric Chloride | Mercury | Mesalamine | Mesna | Metformin | Methamphetamine | Methionine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Mifepristone | Minocycline | Mitotane | morin | myricitrin | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | N-Acetylcysteinamide | NAD | Nandrolone Decanoate | naringenin | naringin | Nelfinavir | Niacin | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nicotine | ochratoxin A | Octreotide | Ofloxacin | Omeprazole | Orlistat | Oxygen | Paraquat | Particulate Matter | Penicillamine | perfluorooctane sulfonic acid | perfluorooctanoic acid | Permethrin | Phenobarbital | Phentolamine | pimagedine | Pioglitazone | piperine | Plant Extracts | Plant Oils | Plant Preparations | Polysaccharides | potassium bromate | Potassium Dichromate | Pravastatin | Progesterone | propacetamol | Propolis | Propoxur | Propranolol | Propylthiouracil | puerarin | Pyrazinamide | pyrazolanthrone | Pyruvaldehyde | Quercetin | Quinacrine | Quinidine | Ranitidine | Resveratrol | Rifampin | Ritonavir | rofecoxib | Rosiglitazone | Rotenone | Rutin | Salicylic Acid | Saponins | Saquinavir | SB 203580 | SB 657510 | Scopolamine | Selenium | Silver | Silymarin | Simvastatin | sodium arsenite | sodium bichromate | Sodium Fluoride | Sodium Selenite | Streptozocin | Styrene | Sulfasalazine | sulforafan | tangeretin | Tapentadol | Taurine | Telmisartan | tert-Butylhydroperoxide | tetrabromobisphenol A | tetrahydrocurcumin | tetrathiomolybdate | Thiamethoxam | Thioacetamide | Thioctic Acid | thymoquinone | Thyroxine | titanium dioxide | Tolbutamide | Tramadol | tri-o-cresyl phosphate | triphenyl phosphate | triptolide | tris(2,3-dibromopropyl)isocyanurate | troxerutin | U 0126 | uranyl acetate | ursolic acid | vanillin | Venlafaxine Hydrochloride | Vitamin E | Vitamin K 3 | Warfarin | Yohimbine | Zearalenone | Zinc | zinc chloride | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate   1978
5. positive regulation of cell death Chemical and Drug Induced Liver Injury Inferred via 292 chemicals: 1-Naphthylisothiocyanate | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2''-galloylhyperin | 3-methylquercetin | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-phenylbutyric acid | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | A 771726 | abamectin | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | Adenosine Triphosphate | Aflatoxin B1 | allyl isothiocyanate | allyl sulfide | Alpha-Amanitin | alpha-Tocopherol | Aluminum Oxide | Amiodarone | Amitriptyline | Antineoplastic Agents | Apigenin | Arsenic | Arsenic Trioxide | arsenite | artemetin | Ascorbic Acid | Aspirin | Atorvastatin | Atrazine | Auranofin | Azacitidine | Azathioprine | Bentonite | Benzene | Bilirubin | Biological Products | bisphenol A | Bortezomib | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | caffeic acid | Carbamazepine | Carboplatin | Carmustine | Catechin | Celecoxib | ceric oxide | cerivastatin | chelerythrine | Chenodeoxycholic Acid | Chlorambucil | chloroacetaldehyde | Chlorogenic Acid | Chloroquine | chloroquine diphosphate | Chlorpromazine | Chlorpyrifos | Cholesterol | chromium hexavalent ion | chrysophanic acid | Cisplatin | Clotrimazole | Clozapine | cobaltous chloride | coenzyme Q10 | Colchicine | Copper | Copper Sulfate | cupric chloride | Curcumin | Cycloheximide | Cyclophosphamide | Cyclosporine | cylindrospermopsin | Cystine | Cytarabine | Dasatinib | Daunorubicin | Deferoxamine | Deoxycholic Acid | deoxynivalenol | Dexamethasone | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Diethylhexyl Phthalate | Digoxin | Dimethyl Sulfoxide | diosbulbin B | Diquat | Disulfiram | Docetaxel | Doxorubicin | Drugs, Chinese Herbal | Dust | Emodin | Endosulfan | Environmental Pollutants | epigallocatechin gallate | Epirubicin | erdosteine | Erlotinib Hydrochloride | Estradiol | Ethanol | Ethinyl Estradiol | Ethionamide | Etoposide | Fenofibrate | Flame Retardants | Fluorouracil | Fluoxetine | Flutamide | Fluvastatin | Fluvoxamine | Folic Acid | Formaldehyde | fumonisin B1 | Gefitinib | Genistein | Glutathione | glyphosate | Halogenated Diphenyl Ethers | Hemin | hesperetin | hexabromocyclododecane | Hydrocarbons, Chlorinated | Hydrogen Peroxide | hydroquinone | Hydroxyurea | Ibuprofen | Imatinib Mesylate | Indomethacin | Iopamidol | Irinotecan | isoliquiritigenin | Isoniazid | Isotretinoin | Ketoconazole | Lansoprazole | Lead | lead acetate | lead chloride | lead nitrate | Leflunomide | Levetiracetam | Lipids | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lithocholic Acid | Lomustine | Lovastatin | lucidone | Malondialdehyde | Maneb | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Melatonin | Meloxicam | Mercaptopurine | Mercuric Chloride | Methamphetamine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Methylprednisolone | Metyrapone | montelukast | Mycophenolic Acid | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | N-acetyl-4-benzoquinoneimine | Nanotubes, Carbon | Naproxen | necrostatin-1 | nefazodone | Nevirapine | Niacin | Nickel | nickel chloride | nickel sulfate | Nicotine | Nifedipine | nimesulide | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | obeticholic acid | ochratoxin A | Oxaliplatin | Oxygen | Paclitaxel | Palmitates | Paraquat | Paroxetine | Particulate Matter | Pentachlorophenol | Pentoxifylline | perfluorooctane sulfonic acid | perfluorooctanoic acid | Perhexiline | phenanthrene | Phenobarbital | Phenytoin | physcione | Phytochemicals | piperine | Piperonyl Butoxide | Piroxicam | Plant Extracts | Plant Preparations | Polysaccharides | Porphyrins | potassium bromate | potassium chromate(VI) | Pravastatin | Prednisolone | Proadifen | Probenecid | Propranolol | Propylthiouracil | puerarin | pyrazolanthrone | Pyruvaldehyde | Quercetin | Raloxifene Hydrochloride | Reactive Oxygen Species | Reserpine | Resveratrol | Rifampin | Rosiglitazone | Rotenone | Rutin | Salicylic Acid | SB 203580 | Sertraline | Silver | Silymarin | Simvastatin | Smoke | sodium arsenite | Sodium Fluoride | Sodium Selenite | sodium tetrasulfide | Streptozocin | sulforafan | Tacrolimus | Tamoxifen | Taurine | Taurocholic Acid | Temozolomide | Tenofovir | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | tetrathiomolybdate | Thalidomide | Thallium | Thioacetamide | Thioctic Acid | Thioguanine | Thioridazine | Ticlopidine | Ticrynafen | titanium dioxide | Tretinoin | tri-o-cresyl phosphate | triphenyl phosphate | triptolide | Troglitazone | trovafloxacin | U 0126 | usnic acid | Valproic Acid | Vehicle Emissions | Verapamil | Vincristine | Vinyl Chloride | Vitamin B 12 | Vitamin K 3 | yangonin | Zearalenone | Zinc | zinc chloride | Zinc Oxide | zinc protoporphyrin Inferred via 5 genes: AIFM1 | HMGB1 | IL1B | MIR34A | PTGS2 2057
6. glutathione biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 275 chemicals: 1,2,4-triazole | 18alpha-glycyrrhetinic acid | 1-bromopropane | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 3-methylquercetin | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | Alcohols | Aldosterone | Alloxan | allyl isothiocyanate | allyl methyl disulfide | alpha-Linolenic Acid | alpha-naphthoflavone | alpha-Tocopherol | Aluminum | Aluminum Chloride | Amodiaquine | andrographolide | Apigenin | Arecoline | Arsenic | Arsenic Trioxide | arsenite | Artesunate | Ascorbic Acid | astin B | Atenolol | Atorvastatin | Atrazine | baicalein | Bentonite | Benzbromarone | Benzene | Benzo(a)pyrene | Berberine | Betaine | bifendate | Bilirubin | bisphenol A | Bortezomib | Buthionine Sulfoximine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caraway oil | Carbon Tetrachloride | Carmustine | Carnitine | Carvedilol | Ceftriaxone | Charcoal | Chlormethiazole | Chlorodiphenyl (54% Chlorine) | Chlorogenic Acid | Chloroquine | chloroquine diphosphate | Chlorpyrifos | Cholic Acid | chromium hexavalent ion | Cimetidine | Ciprofloxacin | Cisplatin | Clozapine | cobaltous chloride | coenzyme Q10 | Copper | Copper Sulfate | Curcumin | cyanoginosin LR | Cyclophosphamide | Cyclosporine | cylindrospermopsin | DDT | decabromobiphenyl ether | decamethrin | deoxynivalenol | Dexamethasone | diallyl disulfide | Dichloroacetic Acid | Dichlorvos | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | diethyl maleate | Diethylnitrosamine | dihydromyricetin | diisononyl phthalate | Dimethoate | dimethyl mercury | Dimethylnitrosamine | diosbulbin B | dioscin | Doxorubicin | Drugs, Chinese Herbal | eleostearic acid | epigallocatechin gallate | Epirubicin | Ethambutol | Ethanol | Famotidine | ferric chloride | Fish Oils | Floxacillin | Flutamide | Folic Acid | Fomepizole | Formaldehyde | Fructose | fumonisin B1 | Fungal Polysaccharides | Galactosamine | Genistein | Glutathione | Glyburide | glycine propionyl carnitine | glyphosate | Grape Seed Extract | Grape Seed Proanthocyanidins | Hemin | hesperetin | Hesperidin | hexabromocyclododecane | hexachlorobutadiene | Hexachlorocyclohexane | Hyaluronic Acid | Hydrogen Peroxide | Hydroxyapatites | hyperoside | INCB018424 | Indomethacin | Irinotecan | Iron | Isoniazid | Ketoconazole | Lansoprazole | lanthanum oxide | Lead | lead acetate | Limonene | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lycopene | Malathion | manganese chloride | mangiferin | Melatonin | Meloxicam | Mercuric Chloride | Mercury | Mesalamine | Mesna | Metformin | Methamphetamine | Methimazole | Methionine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Mifepristone | Monocrotophos | morin | myricitrin | N-Acetylcysteinamide | NAD | Nandrolone Decanoate | naringenin | naringin | necrostatin-1 | Niacinamide | Nickel | Nicotine | N-Methyl-3,4-methylenedioxyamphetamine | ochratoxin A | Oleanolic Acid | olmesartan | Omeprazole | Orlistat | Oxygen | Ozone | paeonol | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | Phenobarbital | Phenytoin | pimagedine | Pioglitazone | piperine | Plant Extracts | Plant Preparations | Polylactic Acid-Polyglycolic Acid Copolymer | Polysaccharides | potassium bromate | Potassium Dichromate | Proadifen | propacetamol | Propolis | Propoxur | Propylthiouracil | Pyrazinamide | Pyruvaldehyde | Quercetin | Quinidine | Resveratrol | retrorsine | Rifampin | Rosiglitazone | Rotenone | Rutin | Salicylic Acid | salvianolic acid B | Saponins | SB 203580 | SB 657510 | schisandrol A | schizandrer A | schizandrin B | schizandrin C | schizandrol B | Scopolamine | Selenium | Silver | Silymarin | Smoke | sodium arsenite | Sodium Fluoride | Sodium Selenite | Streptozocin | Sulfasalazine | sulforafan | Tacrine | Tacrolimus | tangeretin | Taurine | Telmisartan | TEMPO | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | tetrahydrocurcumin | Thiamethoxam | Thioacetamide | Thioctic Acid | thymoquinone | Thyroxine | titanium dioxide | tri-o-cresyl phosphate | triphenyl phosphate | tris(2,3-dibromopropyl)isocyanurate | Troglitazone | troxerutin | U 0126 | uranyl acetate | ursolic acid | Vehicle Emissions | Venlafaxine Hydrochloride | Vitamin B 12 | Vitamin E | Vitamin K 3 | Yohimbine | Zearalenone | Zinc | zinc chloride | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate Inferred via 2 genes: GCLC | GCLM 1842
7. response to oxidative stress Chemical and Drug Induced Liver Injury Inferred via 263 chemicals: 1,2-Dimethylhydrazine | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester | 3,4,5,3',4'-pentachlorobiphenyl | 3-methylquercetin | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acarbose | Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrolein | Adenosine Triphosphate | Alcohols | allyl alcohol | allyl sulfide | alpha-naphthoflavone | alpha-Tocopherol | Alprazolam | Amino Acids, Peptides, and Proteins | Amiodarone | Amitriptyline | Amlodipine | Amodiaquine | Angiotensin-Converting Enzyme Inhibitors | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atenolol | Atorvastatin | Auranofin | Azathioprine | Benzo(a)pyrene | Berberine | Bilirubin | Biological Products | bisphenol A | Bortezomib | Bromocriptine | bromodichloromethane | Budesonide | Buthionine Sulfoximine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caffeic acid | candesartan | Capsaicin | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Carboplatin | Carnitine | Carvedilol | Ceftriaxone | Celecoxib | Cephaloridine | chelerythrine | Chloramphenicol | Chlorodiphenyl (54% Chlorine) | Chloroquine | ciklavit | Cisplatin | Citalopram | Clozapine | Cocaine | coenzyme Q10 | Colchicine | Copper | cumene hydroperoxide | Curcumin | Cyclophosphamide | Cyclosporine | Cystine | Dapsone | Daunorubicin | DDT | decabromobiphenyl ether | Deferoxamine | Deoxycholic Acid | deoxynivalenol | Dexamethasone | Dexmedetomidine | Dextroamphetamine | Dextromethorphan | Dichlorodiphenyl Dichloroethylene | Diclofenac | Dietary Fats | Dietary Sucrose | diethyl maleate | Diethylnitrosamine | Diltiazem | Dimethylnitrosamine | Diosmin | diphenyldiselenide | Dipyridamole | Diquat | Disulfiram | Docetaxel | Doxorubicin | eleostearic acid | Enalapril | Erythromycin Estolate | Estradiol | Ethanol | Fish Oils | Flavonoids | Fluorouracil | Fluoxetine | flupirtine | Fluvastatin | Fructose | gallium arsenide | Genistein | Gliclazide | Glucocorticoids | Glutathione | Glyburide | Glycochenodeoxycholic Acid | Glycodeoxycholic Acid | Haloperidol | Halothane | Heparin | hesperetin | Hexachlorocyclohexane | Hydrogen Peroxide | Imipramine | Indomethacin | Irbesartan | Iron | Isoniazid | Isotretinoin | Ketotifen | Lead | lead chloride | Lipopolysaccharides | Lithium | Losartan | Lovastatin | Lutein | Malathion | manganese chloride | manumycin | Mefloquine | Melatonin | Meloxicam | Mercury | Methamphetamine | Methimazole | Methionine | methylmercuric chloride | Methylmercury Compounds | Methylphenidate | Methylprednisolone | Mifepristone | Minocycline | Morphine | NAD | Naproxen | naringin | Nelfinavir | Niacin | nickel chloride | Nicotine | Nifedipine | nimesulide | Nimodipine | Nitric Oxide | Nitrofurantoin | ochratoxin A | Olanzapine | olmesartan | Oxaliplatin | Oxygen | Ozone | Paraquat | Particulate Matter | Penicillamine | Pentoxifylline | Peptides | Permethrin | Phenelzine | Phenobarbital | phenyl-N-tert-butylnitrone | Pioglitazone | Plant Extracts | Plant Oils | Plant Preparations | Polyethylene Glycols | Polylactic Acid-Polyglycolic Acid Copolymer | Potassium Dichromate | Pravastatin | Progesterone | Propofol | Propranolol | Propylthiouracil | punicic acid | Quercetin | Quetiapine Fumarate | Quinidine | Ramipril | Reactive Oxygen Species | Reserpine | Resveratrol | Rifampin | Risperidone | Ritonavir | rofecoxib | Rosiglitazone | Rotenone | Rutin | S-Adenosylmethionine | Saponins | Saquinavir | schizandrin B | Scopolamine | Selenium | Sevoflurane | Silver | Silybin | Silymarin | Simvastatin | Smoke | sodium arsenate | sodium arsenite | Sodium Nitrite | Sodium Selenite | Sorafenib | Spironolactone | Streptozocin | Sulfasalazine | sulforafan | Sulindac | Tacrine | Tacrolimus | Tamoxifen | Taurine | Tea | Telmisartan | tert-Butylhydroperoxide | Tetrachlorodibenzodioxin | tetrahydrocurcumin | Thalidomide | Thioacetamide | Thioctic Acid | Thiram | Tiopronin | titanium dioxide | Tolmetin | Tretinoin | Troglitazone | Ursodeoxycholic Acid | Valproic Acid | Vehicle Emissions | Vitamin A | Vitamin E | Vitamin K 3 | Yohimbine | Zearalenone | Zinc | Zinc Sulfate Inferred via 19 genes: ABCC1 | ABCC2 | AIFM1 | APOE | CA3 | CAR3 | CAT | GCLC | GCLM | GSR | HMOX1 | LCN2 | MMP2 | MMP9 | PARK7 | PTGS2 | SOD1 | SOD2 | SOD3 2127
8. positive regulation of apoptotic process Chemical and Drug Induced Liver Injury Inferred via 252 chemicals: 1,3-dichloro-2-propanol | 18alpha-glycyrrhetinic acid | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,4-dichlorophenol | 2-fluoro-N-methyl-4-(7-(quinolin-6-yl-methyl)imidazo(1,2-b)(1,2,4)triazin-2-yl)benzamide | 2''-galloylhyperin | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 4-methylthioamphetamine | 4-nitrophenol | 4-phenylbutyric acid | 6-formylindolo(3,2-b)carbazole | 6-methyl-2-(phenylethynyl)pyridine | Acetaminophen | acetochlor | Acetylcysteine | acifluorfen | Acrylamide | Alloxan | alpha-naphthoflavone | alpha-Tocopherol | Amiodarone | andrographolide | Antineoplastic Agents | Apigenin | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Aspirin | Atorvastatin | Atrazine | Benzo(a)pyrene | Bilirubin | Biological Products | BIRB 796 | bisphenol A | Blood Glucose | Bortezomib | bromodichloromethane | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | caffeic acid | Carbamazepine | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Carvedilol | ceric oxide | Chlorambucil | Chlorodiphenyl (54% Chlorine) | Chloroquine | Chlorpyrifos | Choline | Chromium | chromium hexavalent ion | Cimetidine | Cisplatin | Clotrimazole | cobaltous chloride | Copper | Copper Sulfate | cucurbitacin E | Curcumin | cyanoginosin LR | Cyclophosphamide | Cycloserine | Cyclosporine | Cytarabine | Dactinomycin | Daunorubicin | decamethrin | Deferoxamine | deoxynivalenol | Dexamethasone | Dextroamphetamine | diallyl disulfide | diallyl trisulfide | Diazinon | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Dimethylnitrosamine | dioscin | Disulfiram | Docetaxel | Doxorubicin | Drugs, Chinese Herbal | ebselen | Emodin | Endosulfan | epigallocatechin gallate | Erlotinib Hydrochloride | Estradiol | Ethanol | ethylene dichloride | Etoposide | Fluorouracil | Flutamide | Fluvastatin | Formaldehyde | Fructose | fumonisin B1 | Fungal Polysaccharides | Galactosamine | Gefitinib | Genistein | Gliotoxin | Glutathione | glyphosate | Hemin | hesperetin | Hesperidin | Histamine | Hydrogen Peroxide | hydroquinone | Hydroxyapatites | hyperoside | Ibuprofen | Indocyanine Green | Indomethacin | Iopamidol | Isoniazid | Itraconazole | Ketoconazole | Lapatinib | Lead | lead acetate | lead chloride | lead nitrate | Lipids | Lipopolysaccharides | lonidamine | Lovastatin | Ly-364947 | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | manumycin | Melatonin | Meloxicam | Melphalan | Memantine | Mercuric Chloride | Metformin | Methamphetamine | Methionine | Methotrexate | Methoxsalen | methyleugenol | methylmercuric chloride | Methylmercury Compounds | Minocycline | morin | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | Nanotubes, Carbon | naringenin | necrostatin-1 | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nicotine | Nimodipine | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | obeticholic acid | ochratoxin A | Olanzapine | Oxaliplatin | Oxygen | Paclitaxel | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | perfluorooctanoic acid | Perhexiline | Phycocyanin | Phytochemicals | pimagedine | piperine | Plant Extracts | Plant Preparations | Polylactic Acid-Polyglycolic Acid Copolymer | Polysaccharides | Potassium Dichromate | Progesterone | Propofol | puag-haad | puerarin | Putrescine | pyrazolanthrone | Quercetin | Quinine | Reactive Oxygen Species | Resveratrol | Rifampin | Rosiglitazone | Rotenone | salvianolic acid B | SB 203580 | selenomethylselenocysteine | sesamin | Silver | Silybin | Silymarin | Simvastatin | sodium arsenite | sodium bichromate | Sodium Fluoride | Sodium Nitrite | Sodium Selenite | solanesol | Sorafenib | Streptozocin | sulforafan | Sulindac | Tacrolimus | Tamoxifen | Taurine | tauroursodeoxycholic acid | tebuconazole | Temozolomide | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thioacetamide | Thioguanine | Ticrynafen | Tretinoin | tri-o-cresyl phosphate | triptolide | tris(1,3-dichloro-2-propyl)phosphate | Troglitazone | U 0126 | Ursodeoxycholic Acid | ursolic acid | usnic acid | Valproic Acid | Vehicle Emissions | Verapamil | Vincristine | Vitamin E | Vitamin K 3 | Warfarin | Zearalenone | Zinc | zinc protoporphyrin | Zoledronic Acid Inferred via 26 genes: AIFM1 | BAX | CLU | CTNNB1 | GADD45A | HMGB1 | HMOX1 | IFNG | IL18 | IL1B | IL6 | ITPR1 | KNG1 | MAP3K5 | MIR21 | MIR221 | MIR29B2 | MIR29C | MMP2 | MMP9 | NOX4 | PRKDC | PTGS2 | SOD1 | TGFBR1 | TNF 2088
9. reactive oxygen species biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 248 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 3,4,5,3',4'-pentachlorobiphenyl | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | 3-methylquercetin | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetaminophen | Acetylcysteine | Acrylamide | Adenosine Triphosphate | Aflatoxin B1 | Aldosterone | alpha-naphthoflavone | Aluminum Chloride | Amiodarone | andrographolide | Apigenin | Arecoline | Arsenic | Arsenic Trioxide | arsenite | Artesunate | Ascorbic Acid | Atorvastatin | Atrazine | Azathioprine | baicalein | Benzene | Benzo(a)pyrene | benzonidazole | Berberine | Bilirubin | bisphenol A | Buthionine Sulfoximine | Butylated Hydroxyanisole | Cadmium | Cadmium Chloride | caffeic acid | Carbon Tetrachloride | Carmustine | Catechin | ceric oxide | Chloroquine | Chlorpyrifos | Cholesterol | Choline | chromium hexavalent ion | Ciprofloxacin | Cisplatin | cobaltous chloride | Cocaine | coenzyme Q10 | Copper | Copper Sulfate | cucurbitacin E | cupric chloride | Curcumin | cyanoginosin LR | Cyclosporine | cylindrospermopsin | decabromobiphenyl ether | decamethrin | Deferoxamine | deoxynivalenol | Dexamethasone | diallyl disulfide | diallyl trisulfide | Diazinon | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | dihydromyricetin | diisononyl phthalate | Dimethylformamide | Dimethyl Sulfoxide | dioscin | diphenyldiselenide | Diquat | Disulfiram | Docetaxel | Doxorubicin | Drugs, Chinese Herbal | dysprosium oxide | ebselen | Emodin | Endosulfan | epigallocatechin gallate | Epirubicin | erbium oxide | Estradiol | Ethanol | Ethinyl Estradiol | Etoposide | Fenofibrate | Flame Retardants | Flavonoids | Fluoxetine | Flutamide | Fomepizole | Formaldehyde | Fructose | fucoxanthin | fumonisin B1 | Furazolidone | gadolinium oxide | Galactosamine | Gefitinib | Genistein | Glutathione | Grape Seed Proanthocyanidins | Halogenated Diphenyl Ethers | Hemin | Hesperidin | Hydrogen Peroxide | hydroquinone | hyperoside | Imatinib Mesylate | imperatorin | Indomethacin | Iron | isoliquiritigenin | Ketoprofen | lanthanum oxide | lead acetate | lead nitrate | Leflunomide | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lycopene | magnolol | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Melatonin | Mercaptopurine | Mercuric Chloride | Mercury | Methionine | methylmercuric chloride | Methylmercury Compounds | MitoTEMPO | Monocrotaline | morin | Nanotubes, Carbon | naringenin | naringin | necrostatin-1 | nefazodone | neodymium oxide | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nicotine | nimesulide | Nitric Oxide | ochratoxin A | octamethylcyclotetrasiloxane | Oxygen | Ozone | paeonol | Palmitates | Paraquat | Particulate Matter | Penicillamine | perfluorooctane sulfonic acid | Phloretin | Phytochemicals | Phytol | pimagedine | Plant Extracts | Plant Preparations | Poloxamer | Polyethylene Glycols | Polylactic Acid-Polyglycolic Acid Copolymer | Polyphenols | potassium bromate | Potassium Dichromate | Pravastatin | propacetamol | Propofol | propylene dichloride | puerarin | pyrazolanthrone | Pyruvaldehyde | Quercetin | Quinacrine | Resveratrol | Ritonavir | Rotenone | Rutin | samarium oxide | Saponins | SB 203580 | Scopolamine | sesamin | Silver | Silymarin | Smoke | sodium arsenite | sodium bichromate | sodium bisulfite | Sodium Fluoride | Streptozocin | Styrene | Sulfasalazine | sulforafan | Tacrolimus | Tamoxifen | Taurine | tauroursodeoxycholic acid | Tea | Temozolomide | TEMPO | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | tetrahydrocurcumin | Thalidomide | Thioacetamide | Thioctic Acid | Ticlopidine | titanium dioxide | Tretinoin | Trinitrotoluene | triphenyl phosphate | triptolide | tris(1,3-dichloro-2-propyl)phosphate | troxerutin | U 0126 | Valproic Acid | vanillin | Vehicle Emissions | Verapamil | Vitamin E | Vitamin K 3 | Zearalenone | Zidovudine | zinc chloride | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate | zingerone Inferred via 1 gene: NOX4 1709
10. superoxide dismutase activity Chemical and Drug Induced Liver Injury Inferred via 245 chemicals: 18alpha-glycyrrhetinic acid | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | 4-nitrophenol | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | Alloxan | allyl isothiocyanate | allyl methyl disulfide | alpha-Linolenic Acid | alpha-naphthoflavone | alpha-Tocopherol | Aluminum | Aluminum Chloride | Amiodarone | andrographolide | Apigenin | Arsenic | Arsenic Trioxide | arsenite | Artesunate | Ascorbic Acid | Atenolol | Atorvastatin | Atrazine | Auranofin | Benzo(a)pyrene | Berberine | Betaine | bifendate | Bilirubin | bisphenol A | Buprenorphine | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caffeic acid | Capsaicin | Carbon Tetrachloride | Carnitine | Carvedilol | Chloranil | Chlorodiphenyl (54% Chlorine) | Chlorogenic Acid | Chloroquine | Chlorpyrifos | Cholesterol, Dietary | Choline | Cimetidine | Cisplatin | cobaltous chloride | Cocaine | coenzyme Q10 | Copper | Copper Sulfate | cupric chloride | Curcumin | cyanoginosin LR | Cyclophosphamide | Cyclosporine | cylindrospermopsin | DDT | decabromobiphenyl ether | decamethrin | Deoxycholic Acid | deoxynivalenol | Dexamethasone | diallyl disulfide | Dicamba | Dichloroacetic Acid | Dichlorvos | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | dioscin | Diquat | Ditiocarb | Donepezil | Doxorubicin | Drugs, Chinese Herbal | Dust | eleostearic acid | Emodin | Endosulfan | epigallocatechin gallate | Epirubicin | Ethambutol | Ethanol | Ethylene Glycol | Famotidine | Ficusin | fipronil | Fish Oils | Fluorouracil | Flutamide | Formaldehyde | Fructose | fucoxanthin | fumonisin B1 | Fungal Polysaccharides | Galactosamine | Genistein | Glutathione | Glyburide | glycine propionyl carnitine | Glycocholic Acid | Glycyrrhizic Acid | glyphosate | Grape Seed Extract | Grape Seed Proanthocyanidins | Hemin | hesperetin | Hesperidin | hexabromocyclododecane | Hyaluronic Acid | Hydrogen Peroxide | Hydroxyapatites | hyperoside | Indomethacin | Isoniazid | Lansoprazole | Lead | lead acetate | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lutein | Lycopene | Malathion | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Melatonin | Meloxicam | Mequindox | Mercuric Chloride | Mercury | Metformin | Methionine | Methotrexate | Methylene Blue | methylmercuric chloride | Mitotane | morin | Nandrolone Decanoate | naringenin | naringin | Niacinamide | Nickel | nickel chloride | Nicotine | ochratoxin A | Oleanolic Acid | olmesartan | Omeprazole | Orlistat | Oxygen | Ozone | paeonol | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | perfluorooctanoic acid | Permethrin | Pesticides | Phenobarbital | pimagedine | Pioglitazone | piperine | Plant Extracts | Plant Oils | Plant Preparations | Polylactic Acid-Polyglycolic Acid Copolymer | Polysaccharides | potassium bromate | Potassium Dichromate | Probenecid | propacetamol | Propofol | Propoxur | puerarin | Pyrazinamide | Quercetin | Ranitidine | Resveratrol | Rifampin | Rosiglitazone | Rotenone | Rutin | Salicylic Acid | Saponins | SB 203580 | SB 657510 | schizandrin B | Scopolamine | Selenium | sesamin | Silver | Silymarin | Simvastatin | Smoke | sodium arsenite | Sodium Cholate | Sodium Fluoride | Sodium Selenite | Streptozocin | Styrene | sulforafan | tangeretin | Taurine | Taurocholic Acid | Telmisartan | tert-Butylhydroperoxide | tetrabromobisphenol A | tetrahydrocurcumin | Thioacetamide | Thioctic Acid | Thiram | thymoquinone | Thyroxine | titanium dioxide | Trichlorfon | tri-o-cresyl phosphate | triphenyl phosphate | triptolide | tris(2,3-dibromopropyl)isocyanurate | troxerutin | uranyl acetate | ursolic acid | Vehicle Emissions | Venlafaxine Hydrochloride | Vitamin E | Yohimbine | Zearalenone | Zinc | zinc chloride | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate Inferred via 3 genes: SOD1 | SOD2 | SOD3 1708
11. positive regulation of reactive oxygen species biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 240 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,4-Dinitrophenol | 2''-galloylhyperin | 3,4,5,3',4'-pentachlorobiphenyl | 3-methylquercetin | 4,4'-hexafluorisopropylidene diphenol | 4-nitrophenol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 6-methyl-2-(phenylethynyl)pyridine | Acetaminophen | acetochlor | Acetylcarnitine | Acetylcysteine | Acrylamide | Adenosine Triphosphate | Aflatoxin B1 | Allopurinol | allyl isothiocyanate | allyl sulfide | alpha-naphthoflavone | alpha-Tocopherol | Aluminum Chloride | Amino Acids, Peptides, and Proteins | Amitriptyline | Amodiaquine | Amoxicillin | Amoxicillin-Potassium Clavulanate Combination | andrographolide | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Atorvastatin | Atrazine | Auranofin | Bentonite | Benzbromarone | Benzene | Benzo(a)pyrene | Biological Products | bisphenol A | Blood Glucose | Bortezomib | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | caffeic acid | Carbon Tetrachloride | ceric oxide | Chlorogenic Acid | Chlorpromazine | Chlorpyrifos | Cholesterol | Choline | chrysophanic acid | Cisplatin | Clotrimazole | cobaltous chloride | coenzyme Q10 | Copper | Copper Sulfate | cupric chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclosporine | Dactinomycin | Deferoxamine | deoxynivalenol | Dexamethasone | diallyl disulfide | diallyl trisulfide | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | diethyl phthalate | Dimethyl Sulfoxide | dioscin | Diquat | Disulfiram | Ditiocarb | Docetaxel | Doxorubicin | Drugs, Chinese Herbal | Dust | Emodin | Enalapril | Endosulfan | epigallocatechin gallate | Epirubicin | erdosteine | Erlotinib Hydrochloride | Estradiol | Ethanol | ethylene dichloride | Etoposide | Eugenol | Fluoxetine | Flutamide | Formaldehyde | Fungal Polysaccharides | Gefitinib | Genistein | Glutathione | glyphosate | Grape Seed Extract | Grape Seed Proanthocyanidins | Hemin | Hyaluronic Acid | Hydrogen Peroxide | hydroquinone | hyperoside | Ibuprofen | Irinotecan | Iron | Isoniazid | Ketoconazole | Lead | lead acetate | lead chloride | lead nitrate | Lipids | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | liquiritigenin | liquiritin | Lutein | magnolol | Malondialdehyde | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Melatonin | Memantine | Mercuric Chloride | Metformin | Methamphetamine | Methionine | Methotrexate | Methylene Chloride | methylmercuric chloride | MitoTEMPO | Monocrotaline | morin | Nanotubes, Carbon | naringenin | naringin | nefazodone | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nitric Oxide | obeticholic acid | Oleanolic Acid | Oxygen | oxymatrine | Ozone | Palmitates | Paraquat | Particulate Matter | perfluorododecanoic acid | perfluorooctane sulfonic acid | perfluorooctanoic acid | Perhexiline | Permethrin | phenanthrene | Phycocyanin | Phytochemicals | piperine | pirinixic acid | Plant Extracts | Plant Preparations | Polysaccharides | potassium bromate | Potassium Dichromate | Prazosin | Probenecid | propiconazole | Propranolol | puag-haad | puerarin | pyrazolanthrone | pyrene | Pyruvaldehyde | Quercetin | Reactive Oxygen Species | Resveratrol | Rifampin | Rosiglitazone | Rotenone | Salicylic Acid | SB 203580 | scutellarin | sesamin | Silver | Silymarin | sodium arsenite | sodium bichromate | Sodium Fluoride | Sodium Selenite | solanesol | SRT1720 | Streptozocin | sulforafan | Taurine | Tea | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetrachloroethylene | Thallium | Thiram | Ticlopidine | Ticrynafen | titanium dioxide | Tretinoin | Trichloroethylene | triptolide | tris(1,3-dichloro-2-propyl)phosphate | Troglitazone | U 0126 | usnic acid | Valproic Acid | Vehicle Emissions | Verapamil | Vitamin E | Vitamin K 3 | Zearalenone | Zinc | Zinc Oxide | zinc protoporphyrin | Zoledronic Acid | zomepirac Inferred via 2 genes: IL4 | PARK7 1790
12. regulation of mitochondrial membrane potential Chemical and Drug Induced Liver Injury Inferred via 236 chemicals: 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole | 1,2-Dimethylhydrazine | 1,3-dichloro-2-propanol | 1-aminobenzotriazole | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,4-dichlorophenol | 3-Hydroxybutyric Acid | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrolein | Adenosine Triphosphate | Aflatoxin B1 | alpha-Linolenic Acid | alpha-naphthoflavone | alpha-Tocopherol | Aluminum Chloride | Amiodarone | Amitriptyline | Amlodipine | Amodiaquine | andrographolide | Apigenin | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Aspirin | astin B | Atorvastatin | Auranofin | Benzbromarone | Benzo(a)pyrene | Berberine | bicalutamide | bisphenol A | Bortezomib | Bupropion | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | Capsaicin | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Celecoxib | cerivastatin | Chenodeoxycholic Acid | Chlorambucil | chloroacetaldehyde | Chlorogenic Acid | Chlorpromazine | Chlorpyrifos | Ciprofloxacin | Cisplatin | Clodronic Acid | Clozapine | cobaltous chloride | Cocaine | Copper | corosolic acid | cupric chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclosporine | Dactinomycin | dan-shen root extract | Dasatinib | Daunorubicin | decamethrin | Deferoxamine | Deoxycholic Acid | Dexamethasone | Dexmedetomidine | diallyl trisulfide | Diazinon | Dichlorvos | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | dihydromyricetin | Disulfiram | Docetaxel | Donepezil | Doxorubicin | Drugs, Chinese Herbal | Emodin | Endosulfan | Ephedrine | epigallocatechin gallate | Epirubicin | Estradiol | Ethanol | Etoposide | Fenofibrate | Flame Retardants | Flavonoids | Fluorouracil | Flutamide | Fluvastatin | Fructose | fumonisin B1 | Glutathione | Glyburide | Glycochenodeoxycholic Acid | Grape Seed Extract | Halogenated Diphenyl Ethers | Haloperidol | Hemin | Heparin | hexabromocyclododecane | Hyaluronic Acid | Hydrogen Peroxide | hydroquinone | Imatinib Mesylate | Indomethacin | Irinotecan | Iron | Isoflurane | Lansoprazole | lead acetate | Limonene | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Lycopene | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Melatonin | Methamphetamine | Methylene Blue | Methylmercury Compounds | Mifepristone | Minocycline | Monocrotophos | morin | Morphine | Nanotubes, Carbon | naringenin | naringin | necrostatin-1 | nefazodone | Niacinamide | Nickel | nickel chloride | Nicotine | Nifedipine | Nitric Oxide | Nortriptyline | ochratoxin A | Olanzapine | Oxygen | Paclitaxel | Paraquat | Particulate Matter | Penicillamine | Pentoxifylline | perfluorooctane sulfonic acid | Phenelzine | Phenobarbital | Phenytoin | pimagedine | Plant Extracts | Plant Preparations | Polyethylene Glycols | Polylactic Acid-Polyglycolic Acid Copolymer | Proadifen | Propolis | puerarin | Pyrazinamide | pyrazolanthrone | Pyruvaldehyde | Quercetin | Quetiapine Fumarate | Quinacrine | Reactive Oxygen Species | Resveratrol | Risperidone | Rosiglitazone | Rotenone | salvianolic acid B | Saponins | SB 203580 | Selenium | senecionine | sesamin | sesamol | Sevoflurane | Silver | Silybin | Simvastatin | sodium arsenite | Sodium Fluoride | Sodium Selenite | Sorafenib | SRT1720 | Streptozocin | Sulfasalazine | sulforafan | Sulindac | Tacrolimus | Tamoxifen | Taurine | tauroursodeoxycholic acid | Temozolomide | Terfenadine | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | tetrathiomolybdate | thymoquinone | Ticlopidine | Tretinoin | triptolide | Troglitazone | Ursodeoxycholic Acid | Valproic Acid | Vehicle Emissions | Verapamil | Vincristine | Vinyl Chloride | Vitamin A | Vitamin E | Vitamin K 3 | Zearalenone | Zidovudine | Zinc | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate | Zoledronic Acid Inferred via 4 genes: BAX | PARK7 | SOD1 | SOD2 1795
13. membrane lipid catabolic process Chemical and Drug Induced Liver Injury Inferred via 235 chemicals: 2-methyl-3-(2-((4-nitrooxybutyloxy)carbonyl)vinyl)phenyl ursodeoxycholic acid ester | 3,4,5,3',4'-pentachlorobiphenyl | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 8-epi-prostaglandin F2alpha | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Acyclovir | Alcohols | Allopurinol | Alloxan | allyl alcohol | allyl sulfide | alpha-Linolenic Acid | alpha-Tocopherol | Aluminum | Amino Acids, Peptides, and Proteins | Amiodarone | Amitriptyline | Amlodipine | Arsenic | Ascorbic Acid | Aspirin | Atenolol | Atorvastatin | Atropine | Benzene | Benzo(a)pyrene | beta Carotene | Bilirubin | bisphenol A | Bromocriptine | Buthionine Sulfoximine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium | Cadmium Chloride | caffeic acid | Capsaicin | Carbenicillin | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Carmustine | Carnitine | Carvedilol | Catechin | Cefotiam | Ceftriaxone | Celecoxib | Cephaloridine | Cephalothin | Chlorodiphenyl (54% Chlorine) | chloroquine diphosphate | Chlorpromazine | Cholesterol | Cholic Acid | Choline | ciklavit | Cinnarizine | Cisplatin | Clofibrate | Clotrimazole | cobaltous chloride | Cocaine | coenzyme Q10 | Colchicine | Copper | Copper Sulfate | Creatine | cumene hydroperoxide | cupric chloride | Curcumin | Cyclophosphamide | Cyclosporine | Daunorubicin | decabromobiphenyl ether | Deferoxamine | Deoxycholic Acid | deoxynivalenol | Dexamethasone | Dextroamphetamine | Diclofenac | Diethylhexyl Phthalate | diethyl maleate | Diethylnitrosamine | Diethylstilbestrol | Dimethylnitrosamine | Diosmin | diphenyldiselenide | Dipyridamole | Diquat | Disulfiram | Ditiocarb | Doxorubicin | ebselen | eleostearic acid | Enalapril | Epirubicin | essential 303 forte | Estradiol | Ethanol | ferric chloride | Fish Oils | Flavonoids | Fructose | Gemfibrozil | Glutathione | Glyburide | Glycodeoxycholic Acid | Haloperidol | Halothane | Hemin | Heparin | Hesperidin | hexabromocyclododecane | Hexachlorocyclohexane | Hydrogen Peroxide | Ibuprofen | Indomethacin | Iron | Iron-Dextran Complex | Isoniazid | Isotretinoin | Ketoconazole | Lansoprazole | Lead | Leucovorin | Lipopolysaccharides | Lithium | Lomustine | Losartan | Lovastatin | lucidone | Lutein | Lycopene | magnolol | Malathion | Malondialdehyde | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Melatonin | Methapyrilene | Methionine | Methoxsalen | methylmercuric chloride | Methylmercury Compounds | Methylprednisolone | Metyrapone | Mexiletine | Miconazole | NAD | Naproxen | Niacin | Nickel | nickel chloride | Nicotine | Nifedipine | nimesulide | Nimodipine | Nitric Oxide | ochratoxin A | Octreotide | olmesartan | Omeprazole | Oxygen | Ozone | Paraquat | Penicillamine | Pentoxifylline | Phenobarbital | phenyl-N-tert-butylnitrone | pimagedine | Pioglitazone | Piperonyl Butoxide | Plant Extracts | Plant Preparations | potassium bromate | Proadifen | Probenecid | Promethazine | Propofol | Propranolol | Propylthiouracil | punicic acid | Quercetin | Quetiapine Fumarate | Quinacrine | Quinidine | Ramipril | Reactive Oxygen Species | Reserpine | Resveratrol | Rifampin | Risperidone | Rosiglitazone | Rotenone | Roxithromycin | Rutin | S-Adenosylmethionine | Salicylic Acid | Scopolamine | Selenium | Sevoflurane | Silybin | Silymarin | Simvastatin | Smoke | S-Nitroso-N-Acetylpenicillamine | sodium arsenate | sodium arsenite | Sodium Selenite | Spironolactone | Streptozocin | Tacrolimus | Tamoxifen | Taurine | Telmisartan | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetracycline | Thalidomide | Thioctic Acid | Thioridazine | Thyroxine | Ticlopidine | Tretinoin | Ursodeoxycholic Acid | vanillin | Vitamin A | Vitamin E | Vitamin K 3 | Zinc | Zinc Sulfate   1905
14. lipid oxidation Chemical and Drug Induced Liver Injury Inferred via 227 chemicals: 1,3-dichloro-2-propanol | 2,2'-dithienyl diselenide | 2,3-dimethoxy-1,4-naphthoquinone | 2-Acetylaminofluorene | 2-fluoro-N-methyl-4-(7-(quinolin-6-yl-methyl)imidazo(1,2-b)(1,2,4)triazin-2-yl)benzamide | 4,4'-hexafluorisopropylidene diphenol | 4-nitrophenol | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 8-epi-prostaglandin F2alpha | Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | allicin | Alloxan | alpha-Tocopherol | Aluminum Chloride | Aluminum Oxide | Amlodipine | andrographolide | Anthocyanins | Apigenin | aroclor 1260 | Arsenic | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atenolol | Atrazine | baicalein | barium chloride | Benzo(a)pyrene | beta Carotene | Biflavonoids | bisphenol A | Blood Glucose | boric acid | Buthionine Sulfoximine | Butylated Hydroxyanisole | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Carvedilol | Catechin | Chlorpyrifos | Cholesterol | Cholesterol, Dietary | Choline | chromium hexavalent ion | Cisplatin | Clotrimazole | cobaltous chloride | coenzyme Q10 | Copper | Copper Sulfate | cumene hydroperoxide | cupric chloride | Curcumin | cyanoginosin LR | Cyclophosphamide | Cyclosporine | cyfluthrin | cylindrospermopsin | Daunorubicin | decamethrin | Deoxycholic Acid | Dexamethasone | diallyl disulfide | diallyl trisulfide | Diazinon | Dichlorvos | Diclofenac | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Dihydralazine | Dimethoate | Dimethylnitrosamine | diphenyldiselenide | Doxorubicin | eleostearic acid | Enalapril | Endosulfan | epigallocatechin gallate | Estradiol | Ethanol | Eugenol | Fenofibrate | Fluoxetine | Flutamide | Fructose | Genistein | Glutathione | Grape Seed Extract | Grape Seed Proanthocyanidins | Hemin | Hydrogen Peroxide | hydroquinone | Ibuprofen | Imipramine | Indomethacin | Irinotecan | Iron | Iron-Dextran Complex | isoliquiritigenin | Lead | lead acetate | lead chloride | lead nitrate | Limonene | Lipid Peroxides | Lipids | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | liquiritigenin | liquiritin | Lutein | Lycopene | Magnesium Oxide | Malondialdehyde | Maneb | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Melatonin | Meloxicam | Mercuric Chloride | Metformin | Methamphetamine | Methionine | Methotrexate | Methoxsalen | Methylene Blue | Methylprednisolone | Mirtazapine | Monocrotaline | Nanotubes, Carbon | naringin | Nickel | nickel sulfate | obeticholic acid | ochratoxin A | Omeprazole | Oxygen | oxymatrine | Ozone | Paraquat | Particulate Matter | Pentoxifylline | perfluorododecanoic acid | perfluorooctanoic acid | Perindopril | Permethrin | Pesticides | phenanthrene | Phloretin | phloretin isonicotinyl hydrazone | Phycocyanin | Phytochemicals | pimagedine | Piperonyl Butoxide | Plant Extracts | Poloxamer | Polylactic Acid-Polyglycolic Acid Copolymer | poly(methyl vinyl ether-co-maleic anhydride) | Polysaccharides | potassium bromate | Potassium Dichromate | Pregabalin | Proadifen | propiconazole | Propolis | puag-haad | puerarin | punicic acid | Pyrazinamide | Quercetin | Reactive Oxygen Species | Resveratrol | Rosiglitazone | Rotenone | Rutin | S-Adenosylmethionine | salecan | scutellarin | Selenium | sesamin | sesamol | Sevoflurane | Silver | Silymarin | Simvastatin | sodium arsenate | sodium arsenite | Sodium Cholate | Sodium Fluoride | Sodium Nitrite | Sodium Selenite | solanesol | SRT1720 | Streptozocin | Sulfasalazine | sulforafan | Tamoxifen | Taurine | Tea | tert-Butylhydroperoxide | tetrahydrocurcumin | Thalidomide | Thioacetamide | Thiobarbituric Acid Reactive Substances | Thioctic Acid | Thiophanate | thymoquinone | Thyroxine | vanillin | Vehicle Emissions | Vincristine | Vitamin E | Vitamin K 3 | Zearalenone | zileuton | Zinc | zinc protoporphyrin | Zinc Sulfate   1552
15. positive regulation of cell proliferation Chemical and Drug Induced Liver Injury Inferred via 204 chemicals: 1,2-Dimethylhydrazine | 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 1-Naphthylisothiocyanate | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-Acetylaminofluorene | 2-fluoro-N-methyl-4-(7-(quinolin-6-yl-methyl)imidazo(1,2-b)(1,2,4)triazin-2-yl)benzamide | 4,4'-diaminodiphenylmethane | 4,4'-hexafluorisopropylidene diphenol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 4-phenylbutyric acid | 6-formylindolo(3,2-b)carbazole | 9,10-Dimethyl-1,2-benzanthracene | Acetylcysteine | Acrylamide | Aflatoxin B1 | Alitretinoin | allyl sulfide | alpha-Tocopherol | Aluminum Chloride | Amino Acids, Peptides, and Proteins | Apigenin | Arsenic | arsenic disulfide | Arsenic Trioxide | arsenite | Ascorbic Acid | Aspirin | Atorvastatin | Atrazine | baicalein | Benzo(a)pyrene | beta Carotene | bicalutamide | Biological Products | bisphenol A | boric acid | Bortezomib | bromodichloromethane | Butylated Hydroxyanisole | Cadmium Chloride | caffeic acid | Capsaicin | Carboplatin | Catechin | chelerythrine | Chlorodiphenyl (54% Chlorine) | Chloroquine | Chlorpyrifos | chromium hexavalent ion | Cisplatin | Clotrimazole | cobaltous chloride | Copper | cupric chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclosporine | Cytarabine | Daunorubicin | deoxynivalenol | Dexamethasone | diallyl disulfide | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dieldrin | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Dimethyl Sulfoxide | Diosmin | Diquat | Disulfiram | Doxorubicin | Drugs, Chinese Herbal | Emodin | Endosulfan | epigallocatechin gallate | Erlotinib Hydrochloride | Estradiol | Ethanol | Ethinyl Estradiol | ethylene dichloride | Etoposide | Fenbendazole | Fenofibrate | fipronil | Fluconazole | flumequine | Fluorouracil | Fluoxetine | Flutamide | Folic Acid | fumonisin B1 | Fungal Polysaccharides | furan | Genistein | Glutathione | glyphosate | hexabromocyclododecane | Hydrogen Peroxide | hyperoside | Imatinib Mesylate | Irinotecan | Iron | isoliquiritigenin | Itraconazole | Ketoconazole | Lapatinib | lead acetate | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | liquiritigenin | Ly-364947 | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Melatonin | Mercuric Chloride | Metformin | Methotrexate | Methoxsalen | Methylene Chloride | methyleugenol | methyl isobutyl ketone | Miconazole | Monocrotaline | morin | Mycophenolic Acid | NAD | Nanotubes, Carbon | naringenin | Niacinamide | Nickel | nickel chloride | Nicotine | Nimodipine | Nitric Oxide | ochratoxin A | Oxaliplatin | Oxygen | Paclitaxel | Paraquat | Paroxetine | Particulate Matter | perfluorooctanoic acid | Permethrin | Phenobarbital | Phytochemicals | piperine | Plant Extracts | Plant Preparations | Polyphenols | Polysaccharides | Porphyrins | Probenecid | prochloraz | Progesterone | Propofol | Propolis | puag-haad | pyrazolanthrone | Pyrogallol | Quercetin | Reactive Oxygen Species | Resveratrol | Salicylic Acid | SB 203580 | scutellarin | Silver | Silybin | Silymarin | sodium arsenite | Sodium Selenite | Sorafenib | Styrene | sulforafan | Tamoxifen | Tea | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetrachloroethylene | tetrathiomolybdate | Thioacetamide | Thioguanine | thymoquinone | titanium dioxide | Tretinoin | Trichloroethylene | Triiodothyronine | triphenyl phosphate | tris(1,3-dichloro-2-propyl)phosphate | tris(2,3-dibromopropyl)isocyanurate | trovafloxacin | U 0126 | ursolic acid | Valproic Acid | Vincristine | Vitamin E | Warfarin | Zearalenone | Zinc | Zinc Oxide | zinc protoporphyrin Inferred via 27 genes: CDC25B | CLU | CSF3 | CTNNB1 | CXCL10 | FLT1 | HMGB1 | IFNG | IGF1 | IL11 | IL18 | IL1B | IL4 | IL6 | KITL | LGALS3 | MED1 | MIR1290 | MIR132 | MIR141 | MIR21 | MST1R | PTGS2 | SHC1 | TGFBR1 | TNF | VEGFA 1255
16. glutathione metabolic process Chemical and Drug Induced Liver Injury Inferred via 200 chemicals: 1,3-dichloro-2-propanol | 2,2'-dithienyl diselenide | 2,3-dimethoxy-1,4-naphthoquinone | 2''-galloylhyperin | 4,4'-hexafluorisopropylidene diphenol | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | Alloxan | allyl isothiocyanate | alpha-Tocopherol | Aluminum Chloride | Aluminum Oxide | Amodiaquine | aroclor 1260 | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Aspirin | Atrazine | barium chloride | Benzbromarone | Benzo(a)pyrene | beta Carotene | Biflavonoids | bisphenol A | Blood Glucose | boric acid | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Catechin | ceric oxide | Chlorpyrifos | Cholesterol | Cholesterol, Dietary | chromium hexavalent ion | Cisplatin | cobaltous chloride | coenzyme Q10 | Copper | Curcumin | Cycloheximide | Cyclophosphamide | Cyclosporine | Dactinomycin | decabromobiphenyl ether | Deferoxamine | Dexamethasone | diallyl trisulfide | Dichlorvos | Diclofenac | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Dimethoate | diosbulbin B | Disulfiram | Doxorubicin | eleostearic acid | Emodin | Enalapril | Endosulfan | Environmental Pollutants | epigallocatechin gallate | Estradiol | Ethanol | Eugenol | Fenofibrate | Flavonoids | Fluoxetine | Flutamide | Fructose | Genistein | Glutathione | Glyburide | glyphosate | Hemin | Hydrogen Peroxide | Ibuprofen | Iron-Dextran Complex | Ketoconazole | Lead | lead acetate | lead chloride | lead nitrate | Levofloxacin | Limonene | Lipids | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | liquiritigenin | liquiritin | Lutein | Lycopene | Magnesium Oxide | Maneb | manganese chloride | mangiferin | Melatonin | Mercuric Chloride | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Methylprednisolone | Mirtazapine | MitoTEMPO | Monocrotaline | Nanotubes, Carbon | naringin | nefazodone | Nimodipine | obeticholic acid | Omeprazole | Oxygen | Paraquat | Particulate Matter | Peptides | perfluorooctane sulfonic acid | phenanthrene | Phytochemicals | pimagedine | Plant Extracts | Plant Oils | Poloxamer | Polylactic Acid-Polyglycolic Acid Copolymer | poly(methyl vinyl ether-co-maleic anhydride) | potassium bromate | Potassium Dichromate | Pregabalin | Proadifen | Propolis | Propranolol | Propylthiouracil | puag-haad | puerarin | punicic acid | Pyrazinamide | pyrene | Pyruvaldehyde | Quercetin | Reactive Oxygen Species | Resveratrol | Rosiglitazone | Rotenone | S-Adenosylmethionine | salecan | Selenium | Sertraline | sesamol | Silver | Silymarin | Simvastatin | sodium arsenate | sodium arsenite | Sodium Cholate | Sodium Fluoride | Sodium Nitrite | Sodium Selenite | solanesol | SRT1720 | Streptozocin | Sulfasalazine | sulforafan | Tamoxifen | Taurine | Tea | tert-Butylhydroperoxide | tetrahydrocurcumin | Thallium | Thioacetamide | Thioctic Acid | Thiophanate | thymoquinone | Ticlopidine | Ticrynafen | titanium dioxide | Tretinoin | triphenyl phosphate | Troglitazone | U 0126 | usnic acid | Valproic Acid | vanillin | Vehicle Emissions | Verapamil | Vincristine | Vitamin E | Zearalenone | Zinc | zinc protoporphyrin | zomepirac Inferred via 13 genes: GCLC | GCLM | GSR | GSTA4 | GSTM1 | GSTM2 | GSTM3 | GSTM4 | GSTO1 | GSTP1 | GSTT1 | SOD1 | SOD2 1560
17. regulation of blood pressure Chemical and Drug Induced Liver Injury Inferred via 199 chemicals: Acarbose | Acetaminophen | Acetylcarnitine | Acetylcysteine | Adenosine Triphosphate | Aldosterone | Alloxan | alpha-Tocopherol | Alprazolam | Alprostadil | Amitriptyline | Amlodipine | Amoxapine | Angiotensin-Converting Enzyme Inhibitors | Arecoline | Arsenic | Ascorbic Acid | Aspirin | Atenolol | Atomoxetine Hydrochloride | Atorvastatin | Atrazine | Atropine | Baclofen | Benzodiazepines | Bezafibrate | Bosentan | Bromocriptine | Buprenorphine | Bupropion | Buthionine Sulfoximine | candesartan | Capsaicin | Carbidopa | Carnitine | Carvedilol | Celecoxib | cerivastatin | Chloramphenicol | Chlordiazepoxide | Chloroquine | Chlorpromazine | Chlorthalidone | Choline | Cimetidine | Cisapride | Clofibrate | Cocaine | Copper | Cyclosporine | Cyproheptadine | Desflurane | Desipramine | Dexamethasone | Dexmedetomidine | Dextroamphetamine | Dextromethorphan | Diclofenac | Dietary Sucrose | Diethylstilbestrol | Digoxin | Dihydralazine | Diltiazem | Diphenhydramine | Dipyridamole | Disopyramide | Disulfiram | Ditiocarb | Drugs, Chinese Herbal | Dust | Enalapril | Enflurane | entacapone | Ephedrine | Ethanol | Ethinyl Estradiol | Ethinyl Estradiol-Norgestrel Combination | Famotidine | Fenofibrate | Fluoxetine | Folic Acid | Fosinopril | Fructose | Furosemide | Gliclazide | Glucocorticoids | Glutathione | Glyburide | Haloperidol | Halothane | Hemin | Heparin | Histamine | Hydralazine | Hydrochlorothiazide | Ibuprofen | Imipramine | Indoles | Indomethacin | Inulin | Iopamidol | Irbesartan | Iron | Isoflurane | Labetalol | Lead | Limonene | Lipids | Lipopolysaccharides | Lisinopril | Losartan | lumiracoxib | magnolol | Maprotiline | Melatonin | Mercury | Metformin | Methimazole | Methionine | Methyldopa | Methylphenidate | Methylprednisolone | Mexiletine | Mibefradil | Mifepristone | Morphine | Mycophenolic Acid | NAD | Naltrexone | Nandrolone Decanoate | Naproxen | Niacin | Nickel | Nicotine | Nifedipine | nimesulide | Nimodipine | Nitric Oxide | Nortriptyline | Octreotide | olmesartan | Ondansetron | Orlistat | Oxygen | Ozone | Particulate Matter | Penicillamine | Pentamidine | Pentoxifylline | perfluorooctane sulfonic acid | Perhexiline | Perindopril | Phenelzine | Phenobarbital | Phentolamine | Pioglitazone | Plant Extracts | Polyethylene Glycols | Pravastatin | Prazosin | Propofol | Propranolol | Quercetin | Quinidine | Ramipril | Ranitidine | rentiapril | Reserpine | Ritodrine | rofecoxib | Rosiglitazone | Scopolamine | Sertraline | Sevoflurane | Simvastatin | Smoke | sodium arsenite | Spironolactone | Streptozocin | Sulindac | Sulpiride | Tacrine | Tacrolimus | tasosartan | Taurocholic Acid | Telmisartan | Tetrachlorodibenzodioxin | Thioctic Acid | Thyroxine | Ticrynafen | Tolbutamide | Trazodone | Troglitazone | Valproic Acid | Venlafaxine Hydrochloride | Verapamil | Vitamin E | Warfarin | Yohimbine Inferred via 5 genes: AHR | HMOX1 | PTGS2 | SOD1 | SOD2 2327
18. apoptotic DNA fragmentation Chemical and Drug Induced Liver Injury Inferred via 188 chemicals: 1,2-Dimethylhydrazine | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Adenosine Triphosphate | Aflatoxin B1 | Alendronate | alpha-Tocopherol | Alprostadil | Amiodarone | Amitriptyline | Apigenin | Arsenic Trioxide | Artesunate | Ascorbic Acid | Aspirin | Atenolol | Atorvastatin | Auranofin | Azacitidine | Bortezomib | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | caffeic acid | Capsaicin | Carbon Tetrachloride | Carboplatin | Carvedilol | Celecoxib | ceric oxide | cerivastatin | chelerythrine | Chenodeoxycholic Acid | Chloroquine | Cisplatin | Citalopram | Clofibrate | Cocaine | Colchicine | cupric chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclophosphamide | Cyclosporine | Cytarabine | Dactinomycin | Daunorubicin | Deoxycholic Acid | Dexamethasone | Diclofenac | diethyl maleate | Dimethyl Sulfoxide | Dipyridamole | Disulfiram | Docetaxel | Donepezil | Doxorubicin | Doxycycline | Enalapril | Epirubicin | Estradiol | Estramustine | Ethanol | Etoposide | Flavonoids | Fluorouracil | Fluoxetine | fumonisin B1 | Galactosamine | Genistein | Gliotoxin | Glucocorticoids | Glyburide | Glycochenodeoxycholic Acid | Glycodeoxycholic Acid | Haloperidol | Halothane | Heparin | Hydrogen Peroxide | Hydroxyurea | Ibuprofen | Imipramine | Indoles | Indomethacin | Irinotecan | Isoniazid | Isotretinoin | Lansoprazole | lead nitrate | Lipopolysaccharides | Lithium | Losartan | Lovastatin | Malathion | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Medroxyprogesterone Acetate | Melatonin | Methionine | methylmercuric chloride | Methylprednisolone | Mifepristone | Minocycline | Mitotane | Morphine | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | naringenin | naringin | Nickel | Nicotine | Nifedipine | nimesulide | Nitric Oxide | nodularin | ochratoxin A | olmesartan | Omeprazole | Oxaliplatin | Oxygen | Paclitaxel | Particulate Matter | Pentoxifylline | Perindopril | Phenobarbital | Plant Extracts | Prednisolone | Propranolol | pyrazolanthrone | Pyrrolizidine Alkaloids | Pyruvaldehyde | Quercetin | Reactive Oxygen Species | Resveratrol | Risedronic Acid | rofecoxib | Rosiglitazone | Rotenone | S-Adenosylmethionine | sesamin | Silver | Simvastatin | Smoke | S-Nitroso-N-Acetylpenicillamine | sodium arsenite | Sodium Selenite | Spermidine | Spironolactone | Stavudine | Streptozocin | Sulfasalazine | sulforafan | Sulindac | Tacrine | Tacrolimus | tangeretin | Taurine | tauroursodeoxycholic acid | Tea | Telmisartan | Terfenadine | Tetrachlorodibenzodioxin | Thalidomide | Tolbutamide | Tretinoin | tributyrin | triphenyl phosphate | triptolide | Troglitazone | U 0126 | Uridine | Ursodeoxycholic Acid | Valproic Acid | Vehicle Emissions | Verapamil | Vincristine | Vitamin A | Vitamin E | Vitamin K 3 | Zearalenone | Zinc | zinc chloride | Zinc Sulfate | Zoledronic Acid Inferred via 1 gene: HMGB1 1690
19. DNA damage response, detection of DNA damage Chemical and Drug Induced Liver Injury Inferred via 185 chemicals: 1,3-dichloro-2-propanol | 1-aminobenzotriazole | 1-Naphthylisothiocyanate | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2-Acetylaminofluorene | 3,4,5,3',4'-pentachlorobiphenyl | 3-methylquercetin | 4-biphenylamine | 4-nitrophenol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | 5-(1-(3-fluorophenyl)-1H-pyrazol-4-yl)-2H-tetrazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 9,10-Dimethyl-1,2-benzanthracene | abamectin | Acetaminophen | acetochlor | Acetylcarnitine | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | alachlor | Aldosterone | Alloxan | allyl isothiocyanate | alpha-naphthoflavone | alpha-Tocopherol | Aluminum Chloride | Amphotericin B | Arecoline | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Atrazine | Azathioprine | Bentonite | Benzo(a)pyrene | Berberine | beta Carotene | bisphenol A | Buthionine Sulfoximine | Butylated Hydroxyanisole | Cadmium | Cadmium Chloride | captafol | Carbon Tetrachloride | Carvedilol | Charcoal | Chlorogenic Acid | chromium hexavalent ion | Cisplatin | cobaltous chloride | Cocaine | coenzyme Q10 | Copper | cupric chloride | Curcumin | Cycloheximide | Cyclophosphamide | cylindrospermopsin | decamethrin | Deferoxamine | deoxynivalenol | Dexamethasone | diallyl trisulfide | Diazinon | Dichlorvos | Diclofenac | Dicofol | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | Dimethylformamide | dimethyl mercury | Dimethylnitrosamine | Diosmin | Diquat | Ditiocarb | Doxorubicin | Dronedarone | Environmental Pollutants | epigallocatechin gallate | Estradiol | Ethambutol | Ethanol | Etoposide | fipronil | Fish Oils | Flame Retardants | folpet | Formaldehyde | fumonisin B1 | Glutathione | glyphosate | Grape Seed Extract | Grape Seed Proanthocyanidins | Halogenated Diphenyl Ethers | Hemin | hexabromocyclododecane | Hydralazine | Hydrogen Peroxide | hydroquinone | Hydroxyurea | imidacloprid | Inulin | Isoniazid | Lithocholic Acid | Losartan | Maneb | manganese chloride | Melatonin | Mercaptopurine | Mercuric Chloride | Metformin | Methionine | Methylene Blue | methyleugenol | Methylmercury Compounds | NAD | Nandrolone Decanoate | Nanotubes, Carbon | naringin | Niacinamide | Nickel | Nicotine | ochratoxin A | octamethylcyclotetrasiloxane | Oxygen | Ozone | Paclitaxel | Paraquat | Particulate Matter | Pentachlorophenol | perfluorooctane sulfonic acid | Permethrin | Phenobarbital | Phenytoin | Plant Extracts | Polylactic Acid-Polyglycolic Acid Copolymer | Polysaccharides | Potassium Dichromate | Pregnenolone Carbonitrile | propacetamol | propylene dichloride | Pyrazinamide | Quercetin | Resveratrol | Rifampin | Rotenone | Selenium | senecionine | Silver | Silymarin | Simvastatin | sodium arsenite | sodium bichromate | Spironolactone | Streptozocin | sulforafan | Taurine | Temozolomide | tert-Butylhydroperoxide | Thalidomide | theaflavin | Thioacetamide | Thiram | titanium dioxide | tris(2,3-dibromopropyl)isocyanurate | U 0126 | usnic acid | Valproic Acid | Vehicle Emissions | vinylidene chloride | Vitamin E | Vitamin K 3 | Zearalenone | Zidovudine | Zinc | Zinc Oxide | Zinc Sulfate | zingerone Inferred via 1 gene: DDB1 1482
20. glutathione peroxidase activity Chemical and Drug Induced Liver Injury Inferred via 179 chemicals: 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 3,4,5,3',4'-pentachlorobiphenyl | 4-nitrophenol | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | Alloxan | allyl isothiocyanate | allyl methyl disulfide | almond oil | alpha-Linolenic Acid | Aluminum Chloride | andrographolide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atenolol | Atorvastatin | Atrazine | Benzo(a)pyrene | benzonidazole | Berberine | Betaine | bifendate | bisphenol A | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | Carbon Tetrachloride | Chlorogenic Acid | Chloroquine | Chlorpyrifos | Cholesterol, Dietary | Choline | chromium hexavalent ion | Cisplatin | Clozapine | cobaltous chloride | Copper | Copper Sulfate | Curcumin | Cyclophosphamide | Cyclosporine | decabromobiphenyl ether | deoxynivalenol | Dexamethasone | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | Diethylnitrosamine | diosbulbin B | dioscin | diphenyldiselenide | Diquat | Ditiocarb | Doxorubicin | eleostearic acid | Emodin | epigallocatechin gallate | essential 303 forte | Ethanol | Ficusin | Fish Oils | Fluorouracil | Formaldehyde | Fructose | Genistein | Glyburide | Glycyrrhizic Acid | Grape Seed Proanthocyanidins | hesperetin | Hesperidin | hexabromocyclododecane | Hydrogen Peroxide | Hydroxyapatites | hyperoside | Indomethacin | Lead | lead acetate | Lipopolysaccharides | Lycopene | Malathion | Malondialdehyde | manganese chloride | mangiferin | Melatonin | Meloxicam | Mequindox | Mercuric Chloride | Mercury | Metformin | Methamphetamine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Microcystins | Mifepristone | morin | naringenin | naringin | nickel chloride | Nicotine | ochratoxin A | Orlistat | Oxygen | Ozone | Paraquat | Particulate Matter | Pesticides | Phenobarbital | Phytochemicals | Pioglitazone | piperine | Plant Extracts | Plant Preparations | Polysaccharides | potassium bromate | Potassium Dichromate | Probenecid | propacetamol | Propofol | Propylthiouracil | puerarin | Pyruvaldehyde | Quercetin | Ranitidine | Resveratrol | Rosiglitazone | Rotenone | Rutin | Salicylic Acid | salvianolic acid B | Saponins | Scopolamine | Selenium | Silver | Silymarin | Simvastatin | Smoke | sodium arsenite | Sodium Fluoride | Sodium Selenite | Streptozocin | Tacrine | tangeretin | Taurine | Telmisartan | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | tetrahydrocurcumin | Thioacetamide | Thioctic Acid | Thiram | thymoquinone | titanium dioxide | tri-o-cresyl phosphate | triphenyl phosphate | triptolide | troxerutin | U 0126 | uranyl acetate | ursolic acid | vanillin | Vehicle Emissions | Vitamin E | Vitamin K 3 | Zearalenone | Zinc | zinc chloride | Zinc Oxide | Zinc Sulfate Inferred via 3 genes: GSTM2 | GSTP1 | GSTT1 1387
21. reactive oxygen species metabolic process Chemical and Drug Induced Liver Injury Inferred via 168 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Adenosine Triphosphate | Aflatoxin B1 | Aldosterone | Allopurinol | allyl sulfide | alpha-Tocopherol | Apigenin | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | astin B | Atorvastatin | Atrazine | Azathioprine | baicalein | Benzbromarone | Benzo(a)pyrene | Bilirubin | Biological Products | bisphenol A | Buthionine Sulfoximine | Butylated Hydroxyanisole | Cadmium | Cadmium Chloride | caffeic acid | Capsaicin | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | ceric oxide | Chloranil | Chlorodiphenyl (54% Chlorine) | Chloroquine | Chlorpromazine | Chlorpyrifos | chromium hexavalent ion | cobaltous chloride | Copper | Copper Sulfate | cupric chloride | Curcumin | DDT | Deferoxamine | Dexamethasone | diallyl trisulfide | Dichlorvos | diethyl maleate | Diethylnitrosamine | diethyl phthalate | Diethylstilbestrol | Dimethoate | diosbulbin B | Diosmin | Doxorubicin | Drugs, Chinese Herbal | Endosulfan | epigallocatechin gallate | Estradiol | Ethanol | Etoposide | Flutamide | Fructose | Fungal Polysaccharides | Genistein | Glutathione | Grape Seed Extract | Hemin | Hesperidin | hexabromocyclododecane | Hydrocarbons, Chlorinated | Hydrogen Peroxide | hydroquinone | imperatorin | Isoflurane | lead acetate | lead nitrate | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lycopene | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Melatonin | Metformin | Methylmercury Compounds | Methylphenidate | Monocrotophos | morin | myricitrin | NAD | Nanotubes, Carbon | naringenin | naringin | necrostatin-1 | nefazodone | neohesperidin dihydrochalcone | Niacinamide | Nickel | nickel chloride | nickel sulfate | Nicotine | Nifedipine | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | ochratoxin A | Orphenadrine | Oxygen | Paraquat | Particulate Matter | phenanthrene | Phenobarbital | Phenytoin | Phytochemicals | Piperonyl Butoxide | Plant Extracts | Plant Preparations | Polyethylene Glycols | Polylactic Acid-Polyglycolic Acid Copolymer | potassium bromate | Proadifen | Propofol | puag-haad | pyrazolanthrone | Pyruvaldehyde | Quercetin | Reactive Oxygen Species | Resveratrol | Rosiglitazone | Rotenone | Salicylic Acid | Saponins | Selenium | sesamin | Silver | Silybin | Silymarin | Smoke | sodium arsenite | Sodium Fluoride | Sodium Selenite | Streptozocin | sulforafan | TEMPO | tert-Butylhydroperoxide | tetrahydrocurcumin | Thioctic Acid | thymoquinone | triptolide | troxerutin | ursolic acid | Vehicle Emissions | Verapamil | Vitamin A | Vitamin E | Vitamin K 3 | Zearalenone | Zinc Oxide | zinc protoporphyrin | Zinc Sulfate Inferred via 8 genes: CAT | IL22 | NDUFS3 | NOX4 | PDK4 | SESN2 | SOD1 | SOD2 1284
22. cell cycle Chemical and Drug Induced Liver Injury Inferred via 156 chemicals: 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 3,4,5,3',4'-pentachlorobiphenyl | 4,4'-hexafluorisopropylidene diphenol | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone | A 771726 | Acetaminophen | Acetylcysteine | Acitretin | Alitretinoin | alpha-naphthoflavone | alpha-Tocopherol | Amlodipine | Apigenin | Arsenic Trioxide | Ascorbic Acid | Aspirin | Astemizole | Atorvastatin | Auranofin | Azacitidine | Benzo(a)pyrene | Berberine | bicalutamide | bisphenol A | Bortezomib | Cadmium | Capsaicin | Carboplatin | Carmustine | Carvedilol | Celecoxib | Chenodeoxycholic Acid | Chloroquine | Cholesterol | Ciprofloxacin | Cisplatin | Clofibrate | Clotrimazole | Cocaine | Colchicine | Curcumin | Cycloheximide | Cyclophosphamide | Cyclosporine | Cytarabine | Dactinomycin | Dasatinib | Daunorubicin | Deferoxamine | Desipramine | Dexamethasone | diallyl disulfide | Diethylstilbestrol | Dipyridamole | Docetaxel | Doxorubicin | efavirenz | Erlotinib Hydrochloride | Erythromycin Estolate | Estradiol | Estramustine | Etoposide | Fish Oils | flumequine | Fluorouracil | Fluvastatin | fumonisin B1 | Galactosamine | Gefitinib | Genistein | Glutathione | glyphosate | Heparin | hesperetin | Hydrogen Peroxide | Hydroxyurea | Ibuprofen | Imatinib Mesylate | Indomethacin | Irinotecan | Isotretinoin | Itraconazole | Lapatinib | Leflunomide | Lithium | Lovastatin | lumiracoxib | Lutein | Lycopene | Melatonin | Melphalan | Methimazole | Methionine | Methotrexate | Methoxsalen | Mifepristone | Morphine | Mycophenolic Acid | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | Naltrexone | Naproxen | Nelfinavir | Nevirapine | Niacin | Nicotine | Nifedipine | nimesulide | Nitric Oxide | Octreotide | Orlistat | Paclitaxel | Penicillamine | Pentoxifylline | Pesticides | Plant Extracts | Prednisolone | Propranolol | pyrazolanthrone | Quinidine | Quinine | Raloxifene Hydrochloride | Reactive Oxygen Species | Resveratrol | Rifampin | Risedronic Acid | Ritonavir | Rosiglitazone | Rotenone | SB 203580 | Simvastatin | sodium arsenite | Sodium Selenite | Sorafenib | Streptozocin | sulforafan | Sulindac | Tacrolimus | Tamoxifen | Temozolomide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thalidomide | Thioacetamide | Thioctic Acid | Tretinoin | tributyrin | Triiodothyronine | triptolide | Troglitazone | Ursodeoxycholic Acid | Valproic Acid | Vincristine | Vitamin A | Vitamin E | Zearalenone | Zidovudine Inferred via 7 genes: AHR | CDC25B | GADD45A | KRT18 | SNX18 | SPIN2A | WASL 1454
23. positive regulation of superoxide dismutase activity Chemical and Drug Induced Liver Injury Inferred via 142 chemicals: 2,2',4,4',5-brominated diphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 4,4'-hexafluorisopropylidene diphenol | 4-nitrophenol | Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrylamide | allicin | alpha-Tocopherol | Aluminum Chloride | Amlodipine | Anthocyanins | Apigenin | aroclor 1260 | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Atrazine | Benzo(a)pyrene | beta Carotene | Biflavonoids | bisphenol A | Blood Glucose | boric acid | Butylated Hydroxyanisole | Cadmium Chloride | Carbon Tetrachloride | Carvedilol | Catechin | Chlorpromazine | Chlorpyrifos | Cholesterol | Cisplatin | cobaltous chloride | coenzyme Q10 | Copper | Copper Sulfate | corvitin | cupric chloride | Curcumin | cyanoginosin LR | Cyclophosphamide | Cyclosporine | cyfluthrin | cylindrospermopsin | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dichlorvos | Diclofenac | Dietary Fats | Dihydralazine | Dimethoate | Doxorubicin | Drugs, Chinese Herbal | eleostearic acid | Endosulfan | epigallocatechin gallate | Ethanol | Etoposide | Fenofibrate | Fluoxetine | Fructose | Genistein | Glutathione | Glyburide | Hydrogen Peroxide | Ibuprofen | isoliquiritigenin | lead acetate | lead nitrate | Lipids | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lycopene | Maneb | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Melatonin | Meloxicam | Mercuric Chloride | Methotrexate | Methylene Blue | Methylprednisolone | Nanotubes, Carbon | naringin | nickel sulfate | ochratoxin A | Omeprazole | Oxygen | oxymatrine | Paraquat | Penicillamine | perfluorododecanoic acid | perfluorooctanoic acid | Perindopril | Pesticides | phenanthrene | Phycocyanin | Phytochemicals | Plant Extracts | Polyphenols | Polysaccharides | potassium bromate | Potassium Dichromate | Pregabalin | propiconazole | Propolis | puerarin | punicic acid | Quercetin | Reactive Oxygen Species | Resveratrol | Rotenone | Saponins | Selenium | sesamin | sesamol | Silver | Silymarin | sodium arsenate | sodium arsenite | Sodium Nitrite | Streptozocin | Sulfasalazine | sulforafan | Taurine | Tea | tetrahydrocurcumin | Thalidomide | Thioctic Acid | Thiophanate | thymoquinone | titanium dioxide | triptolide | vanillin | Vincristine | Zearalenone | Zinc | Zinc Sulfate Inferred via 3 genes: PARK7 | RGN | TNF 1206
24. mitotic cell cycle arrest Chemical and Drug Induced Liver Injury Inferred via 139 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 3-methylquercetin | Acetylcysteine | Acrylamide | ado-trastuzumab emtansine | Aflatoxin B1 | alpha-naphthoflavone | alpha-Tocopherol | andrographolide | Apigenin | Arecoline | Arsenic | arsenic disulfide | Arsenic Trioxide | arsenite | Ascorbic Acid | Atrazine | Azathioprine | baicalein | Benzo(a)pyrene | Berberine | beta Carotene | Betaine | bisphenol A | Buthionine Sulfoximine | Butylated Hydroxyanisole | Cadmium | Cadmium Chloride | Carmustine | ceric oxide | cerous chloride | Chlorpyrifos | Cisplatin | cobaltous chloride | corosolic acid | cupric chloride | Curcumin | Cytarabine | Dasatinib | diallyl trisulfide | Diazinon | Dichlorvos | diethyl maleate | Disulfiram | Docetaxel | Doxorubicin | Dronedarone | Drugs, Chinese Herbal | Endosulfan | epigallocatechin gallate | Ethambutol | Ethanol | Ethionamide | Etoposide | Flame Retardants | Fluorouracil | Folic Acid | Formaldehyde | fumonisin B1 | Fungal Polysaccharides | furan | Furazolidone | Gefitinib | Glutathione | Halogenated Diphenyl Ethers | Hydrogen Peroxide | hydroquinone | Hydroxyurea | hyperoside | Imatinib Mesylate | Irinotecan | isoliquiritigenin | Isoniazid | lead acetate | magnolol | manganese chloride | mangiferin | Melatonin | Mercaptopurine | Metformin | Methamphetamine | Methionine | Methotrexate | naringin | Niacinamide | nickel chloride | Nicotine | ochratoxin A | Oleanolic Acid | Oxaliplatin | Oxygen | Paclitaxel | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pesticides | Phytochemicals | Plant Extracts | Plant Preparations | Polyethylene Glycols | Pregnenolone Carbonitrile | Propofol | Pyrazinamide | pyrazolanthrone | Quercetin | Resveratrol | Rifampin | Rosiglitazone | Rotenone | Rutin | SB 203580 | selenomethylselenocysteine | Silver | Silybin | Smoke | sodium arsenite | Sodium Selenite | Sorafenib | sulforafan | tangeretin | Taurine | Temozolomide | Tetrachlorodibenzodioxin | tetrathiomolybdate | titanium dioxide | Tretinoin | Triiodothyronine | triptolide | trovafloxacin | U 0126 | ursolic acid | Valproic Acid | Vincristine | Zearalenone | Zinc | zinc protoporphyrin | Zinc Sulfate Inferred via 1 gene: GADD45A 965
25. nitric oxide biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 135 chemicals: 18alpha-glycyrrhetinic acid | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Adenosine Triphosphate | Aflatoxin B1 | Allopurinol | alpha-naphthoflavone | Amphotericin B | amyrone | Apigenin | Arsenic | Ascorbic Acid | Atorvastatin | Benzene | Benzo(a)pyrene | Berberine | bifendate | bisphenol A | boric acid | Cadmium | Cadmium Chloride | Carbon Tetrachloride | Celecoxib | Chloroquine | Chlorpyrifos | Choline | Cisplatin | Clotrimazole | cobaltous chloride | coenzyme Q10 | Copper | cupric chloride | Curcumin | Cyclosporine | decamethrin | Dexamethasone | diallyl trisulfide | Dichlorvos | Dietary Fats | Diethylnitrosamine | Dimethoate | Donepezil | Doxorubicin | Drugs, Chinese Herbal | Endosulfan | Ethanol | Etoposide | fipronil | Flutamide | Formaldehyde | Fructose | fucoxanthin | gadolinium chloride | Genistein | Glyburide | Grape Seed Proanthocyanidins | Hemin | hesperetin | Hydrogen Peroxide | Imatinib Mesylate | INCB018424 | Indomethacin | Irinotecan | Lansoprazole | lanthanum oxide | Limonene | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | lipoteichoic acid | Losartan | Lovastatin | manganese chloride | mangiferin | Melatonin | Mercuric Chloride | Mesalamine | Methamphetamine | Methionine | Methotrexate | methylmercuric chloride | Methylmercury Compounds | Methylprednisolone | Mifepristone | morin | Nandrolone Decanoate | Nanotubes, Carbon | naringenin | naringin | Niacin | Nickel | nickel sulfate | Nitric Oxide | Omeprazole | Paraquat | Particulate Matter | Phenobarbital | Phytochemicals | pimagedine | Plant Extracts | Plant Preparations | Polymyxin B | Polysaccharides | potassium bromate | pyrazolanthrone | Pyruvaldehyde | Quercetin | Resveratrol | Rotenone | Rutin | salvianolic acid B | SB 203580 | Selenium | Silver | Silymarin | sodium arsenite | Sodium Fluoride | Sodium Selenite | Streptozocin | Sulfasalazine | tangeretin | Taurine | tauroursodeoxycholic acid | Telmisartan | tert-Butylhydroperoxide | Thioctic Acid | thymoquinone | titanium dioxide | ursolic acid | Venlafaxine Hydrochloride | Vitamin E | Zinc Oxide   1212
26. vasodilation Chemical and Drug Induced Liver Injury Inferred via 128 chemicals: 1,3-dipropyl-8-cyclopentylxanthine | 3-methylquercetin | Acetylcarnitine | Acetylcysteine | Adenosine Triphosphate | Alcohols | Alprostadil | Aluminum Chloride | Amiodarone | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Aspirin | Atorvastatin | Atropine | barium chloride | Bosentan | Bromocriptine | Budesonide | candesartan | Capsaicin | Carbon Tetrachloride | Carvedilol | Celecoxib | chelerythrine | Chlorpromazine | Cholesterol | Cimetidine | Cinnarizine | Clopidogrel | Clotrimazole | Cocaine | Cyclosporine | Desflurane | Dexamethasone | Dextroamphetamine | Dextromethorphan | Diatrizoate Meglumine | Diclofenac | Dietary Fats | Diltiazem | Diphenhydramine | Dipyridamole | Enalapril | Enflurane | Estradiol | Ethanol | Famotidine | Fructose | Furosemide | Gliclazide | Glutathione | Glyburide | Haloperidol | Halothane | Heparin | Histamine | Hydralazine | Ibuprofen | Indoles | Indomethacin | Irbesartan | Iron | Isoflurane | Labetalol | Lipids | Lipopolysaccharides | Losartan | Mercuric Chloride | Metformin | Methylene Blue | Mexiletine | Miconazole | Mifepristone | Monocrotaline | Morphine | Naltrexone | Nanotubes, Carbon | Niacin | Nicotine | Nifedipine | Nimodipine | Nitric Oxide | olmesartan | Oxygen | Particulate Matter | Pentoxifylline | Peptides | Perindopril | Phentolamine | phenyl-N-tert-butylnitrone | Piroxicam | Polyethylene Glycols | Polysorbates | Pravastatin | Prazosin | Progesterone | Promethazine | Propofol | Propranolol | Quercetin | Quinidine | Ramipril | Ranitidine | Reserpine | Resveratrol | Rosiglitazone | Sertraline | Sevoflurane | Simvastatin | Smoke | sodium arsenite | Sodium Fluoride | Sodium Nitrite | Streptozocin | Sulpiride | Tamoxifen | Telmisartan | Tetrachlorodibenzodioxin | Thioctic Acid | Thyroxine | titanium dioxide | Tolbutamide | Tretinoin | Troglitazone | Vehicle Emissions | Verapamil | Vitamin E | Yohimbine Inferred via 6 genes: ALB | APOE | ATG5 | CPS1 | KNG1 | SOD2 1085
27. positive regulation of mitochondrial membrane potential Chemical and Drug Induced Liver Injury Inferred via 127 chemicals: 1,3-dichloro-2-propanol | 2,2',4,4'-tetrabromodiphenyl ether | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2,4-dichlorophenol | 2,4-Dinitrophenol | 2''-galloylhyperin | 4-phenylbutyric acid | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetaminophen | Acetylcarnitine | Acetylcysteine | Adenosine Triphosphate | alpha-Tocopherol | Arsenic | Arsenic Trioxide | Ascorbic Acid | Benzbromarone | beta-hexachlorocyclohexane | Biological Products | bisphenol A | Cadmium | Cadmium Chloride | caffeic acid | Carbon Tetrachloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | ceric oxide | Chlorpyrifos | chromium hexavalent ion | chrysophanic acid | Cisplatin | cobaltous chloride | Curcumin | cyanoginosin LR | Cycloheximide | Cyclosporine | Dactinomycin | Daunorubicin | diallyl trisulfide | Dichloroacetic Acid | Dichlorodiphenyl Dichloroethylene | Diclofenac | Diethylhexyl Phthalate | Diquat | Disulfiram | Doxorubicin | Drugs, Chinese Herbal | ebselen | Emodin | epigallocatechin gallate | Estradiol | Eugenol | Flutamide | Gefitinib | Genistein | Glutathione | Grape Seed Proanthocyanidins | Hydrogen Peroxide | Ibuprofen | Isoniazid | Lead | lead acetate | lead nitrate | Levofloxacin | Lipids | Lipopolysaccharides | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercuric Chloride | Metformin | naringin | nefazodone | Orlistat | Oxygen | Paclitaxel | Palmitates | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | Perhexiline | Phytochemicals | pimagedine | Pioglitazone | Plant Extracts | Plant Preparations | potassium chromate(VI) | Propranolol | Propylthiouracil | puag-haad | puerarin | Pyruvaldehyde | Quercetin | Reactive Oxygen Species | Resveratrol | Rifampin | Rotenone | Rutin | Salicylic Acid | SB 203580 | Selenium | Sevoflurane | Silver | S-Nitroso-N-Acetylpenicillamine | sodium arsenite | sodium bichromate | Sodium Selenite | Sorafenib | sulforafan | Tamoxifen | tert-Butylhydroperoxide | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetraethyl Lead | Thallium | Thiabendazole | Thioctic Acid | Thioridazine | Ticlopidine | Ticrynafen | Trichloroethylene | triptolide | tris(1,3-dichloro-2-propyl)phosphate | Troglitazone | U 0126 | Valproic Acid | Vincristine | Zinc   1215
28. vasoconstriction Chemical and Drug Induced Liver Injury Inferred via 125 chemicals: 1-aminobenzotriazole | 3-methylquercetin | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 8-epi-prostaglandin F2alpha | Acetylcysteine | Adenosine Triphosphate | Aldosterone | Alprostadil | Aluminum Chloride | Amiodarone | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Aspirin | Atenolol | Atropine | barium chloride | Bosentan | Budesonide | Buthionine Sulfoximine | Cadmium | candesartan | Capsaicin | Carvedilol | chelerythrine | Cimetidine | Cinnarizine | Cisplatin | Cocaine | Copper | Curcumin | Cyclosporine | Cyproheptadine | Dactinomycin | Dantrolene | Desflurane | Dexamethasone | Dexmedetomidine | Dextroamphetamine | Dextromethorphan | Diatrizoate Meglumine | Dietary Fats | Digoxin | Diltiazem | Dimethyl Sulfoxide | Dipyridamole | Ditiocarb | Enalapril | Enflurane | epigallocatechin gallate | Ethanol | Fluorouracil | Fluoxetine | Fructose | Glyburide | Haloperidol | Halothane | Histamine | Hydralazine | Hydrogen Peroxide | Ibuprofen | Imipramine | Indomethacin | Irbesartan | Iron-Dextran Complex | Isoflurane | Ketoprofen | Labetalol | Lipopolysaccharides | Lisinopril | Losartan | mangiferin | Melatonin | Mercuric Chloride | Methamphetamine | Methylene Blue | Mexiletine | Mifepristone | Monocrotaline | Morphine | Mycophenolic Acid | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | Naltrexone | Nicotine | Nifedipine | Nimodipine | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | Octreotide | Oxygen | Particulate Matter | Pentoxifylline | Phentolamine | Plant Extracts | Prazosin | Prednisolone | Proadifen | Progesterone | Propofol | Propranolol | Quercetin | Quinacrine | Quinidine | Ramipril | Ranitidine | Reserpine | Ritodrine | Rosiglitazone | Saponins | Sertraline | Sevoflurane | Smoke | Sorafenib | Spironolactone | Streptozocin | Sulpiride | Tacrolimus | tasosartan | Telmisartan | tert-Butylhydroperoxide | Tetrachlorodibenzodioxin | titanium dioxide | Tolbutamide | Vehicle Emissions | Verapamil | Yohimbine   940
29. protein oxidation Chemical and Drug Induced Liver Injury Inferred via 124 chemicals: 2,2',4,4'-tetrabromodiphenyl ether | 4,4'-hexafluorisopropylidene diphenol | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | Aflatoxin B1 | Alpha-Amanitin | Aluminum Chloride | Anthocyanins | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | baicalein | barium chloride | Benzo(a)pyrene | Biflavonoids | bisphenol A | Blood Glucose | Cadmium | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Chlorodiphenyl (54% Chlorine) | Cholesterol | Cholesterol, Dietary | Cisplatin | cobaltous chloride | Copper | cupric chloride | Curcumin | Dactinomycin | Dexamethasone | Dichlorvos | Dietary Fats | Diethylnitrosamine | Dimethoate | Dimethyl Sulfoxide | Doxorubicin | ebselen | eleostearic acid | Endosulfan | Ethanol | fumonisin B1 | Glutathione | Glyburide | Grape Seed Extract | Hesperidin | Hydrogen Peroxide | Imatinib Mesylate | Irinotecan | Iron | Lead | lead acetate | lead nitrate | Lipopolysaccharides | Losartan | magnolol | Maneb | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | mangiferin | Mercuric Chloride | Methamphetamine | Methionine | Methotrexate | methylmercuric chloride | naringenin | naringin | ochratoxin A | Oxygen | Ozone | Paraquat | Particulate Matter | phenanthrene | Phenobarbital | phenyl-N-tert-butylnitrone | Plant Extracts | Plant Preparations | Polymyxin B | Polysaccharides | potassium bromate | Potassium Dichromate | Pravastatin | propacetamol | propiconazole | puag-haad | puerarin | punicic acid | Pyruvaldehyde | Quercetin | Raloxifene Hydrochloride | Resveratrol | Rotenone | Rutin | Silymarin | Simvastatin | Smoke | S-Nitroso-N-Acetylpenicillamine | sodium arsenite | Sodium Cholate | Sodium Fluoride | Sodium Nitrite | Sodium Selenite | SRT1720 | Streptozocin | Styrene | Sulfasalazine | Tapentadol | Taurine | tert-Butylhydroperoxide | tetrahydrocurcumin | Thioctic Acid | Thiophanate | thymoquinone | Tramadol | vanillin | Vehicle Emissions | Vitamin K 3 | zileuton | Zinc Inferred via 1 gene: APOA1 1132
30. detection of oxidative stress Chemical and Drug Induced Liver Injury Inferred via 124 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | Acetaminophen | Acetylcysteine | Acrolein | Acrylamide | alpha-naphthoflavone | Aluminum Chloride | Amiodarone | Amitriptyline | Arsenic | Ascorbic Acid | Benzo(a)pyrene | Berberine | bisphenol A | Bortezomib | bromodichloromethane | Cadmium | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Ceftriaxone | cerous chloride | Chloramphenicol | Chlormethiazole | chlorodibromomethane | Chlorogenic Acid | Chlorpromazine | Chlorpyrifos | chromium hexavalent ion | Cisplatin | Clozapine | Copper | coumarin | Curcumin | cyanoginosin LR | Cyproterone Acetate | Dantrolene | Dapsone | Dichlorvos | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | Dimethoate | Dipyridamole | Disulfiram | Doxorubicin | Drugs, Chinese Herbal | Enalapril | Ephedrine | epigallocatechin gallate | Ethanol | Ethinyl Estradiol | Felbamate | Flutamide | Fructose | Glyburide | Glycyrrhizic Acid | glyphosate | Grape Seed Proanthocyanidins | Hydrogen Peroxide | Isoniazid | Ketoconazole | Lansoprazole | Lead | lead acetate | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Mercuric Chloride | Metformin | Methapyrilene | Methyldopa | Methylmercury Compounds | Monocrotaline | Monocrotophos | Naltrexone | naringin | Nicotine | Nifedipine | nimesulide | ochratoxin A | Oxygen | Particulate Matter | Penicillamine | Phenacetin | Phenobarbital | Phenytoin | Piperonyl Butoxide | Plant Extracts | Plant Preparations | Pyruvaldehyde | Quercetin | Ranitidine | Resveratrol | Rifampin | Ritonavir | Rosiglitazone | Rutin | Saponins | Selenium | Silver | Simvastatin | sodium arsenite | sodium bichromate | Sodium Selenite | Stavudine | Streptozocin | Sulfamethoxazole | Sulindac | Tamoxifen | Telmisartan | Tenofovir | tetrathiomolybdate | Thioacetamide | titanium dioxide | uranyl acetate | usnic acid | Valproic Acid | Vehicle Emissions | Verapamil | Vitamin E | Zidovudine | Zinc | Zinc Oxide Inferred via 1 gene: ADIPOQ 1369
31. regulation of heart rate Chemical and Drug Induced Liver Injury Inferred via 123 chemicals: Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrolein | Adenosine Triphosphate | Ajmaline | Alloxan | Alprostadil | Amiodarone | Amitriptyline | Amlodipine | Angiotensin-Converting Enzyme Inhibitors | Arsenic | Atenolol | Atropine | Auranofin | Baclofen | Benzo(a)pyrene | Bezafibrate | Capsaicin | Carbidopa | Carnitine | Carvedilol | Chloramphenicol | Cimetidine | Cisapride | Clozapine | Cocaine | Cyclosporine | Cyproheptadine | Desflurane | Desipramine | Dexamethasone | Dexmedetomidine | Dextroamphetamine | Dextromethorphan | Digoxin | Diltiazem | Diphenhydramine | Dipyridamole | Disopyramide | Donepezil | Doxorubicin | Enalapril | Enflurane | Ephedrine | Ethanol | Famotidine | Fluoxetine | Furosemide | glimepiride | Haloperidol | Halothane | Histamine | Hydralazine | Hydrochlorothiazide | Ibuprofen | Imipramine | Indoles | Indomethacin | Iron | Isoflurane | Labetalol | Lead | Lipopolysaccharides | Lithium | Losartan | Maprotiline | Mercury | Methimazole | Methionine | Methyldopa | Methylphenidate | Mexiletine | Morphine | NAD | Naltrexone | Nandrolone Decanoate | Nicotine | Nifedipine | Nimodipine | Nitric Oxide | N-Methyl-3,4-methylenedioxyamphetamine | Nomifensine | Nortriptyline | Ofloxacin | Oxygen | Ozone | Paroxetine | Particulate Matter | Pentamidine | Perhexiline | Perindopril | Phenelzine | Phenobarbital | Phentolamine | Plant Extracts | Prazosin | Propofol | Propranolol | Quinidine | Ranitidine | Reserpine | Ritodrine | Scopolamine | Sevoflurane | Silver | Simvastatin | Smoke | Spironolactone | Streptozocin | Sulpiride | Tacrolimus | Telmisartan | Terfenadine | Tetrachlorodibenzodioxin | Thalidomide | Tolbutamide | Trazodone | triphenyl phosphate | Verapamil | Vitamin B 12 | Yohimbine Inferred via 1 gene: MIR328 1420
32. negative regulation of cell proliferation Chemical and Drug Induced Liver Injury Inferred via 121 chemicals: 1,3-dichloro-2-propanol | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetaminophen | Acetylcysteine | Acitretin | Acrolein | alachlor | Aldosterone | allyl isothiocyanate | alpha-naphthoflavone | andrographolide | Arsenic Trioxide | Ascorbic Acid | Atrazine | baicalein | Benzo(a)pyrene | Biological Products | bisphenol A | Busulfan | Cadmium Chloride | Carbonyl Cyanide m-Chlorophenyl Hydrazone | Chlorodiphenyl (54% Chlorine) | Chlorogenic Acid | Chloroquine | Chlorpyrifos | Cisplatin | cobaltous chloride | Colchicine | Copper Sulfate | corosolic acid | cyanoginosin LR | Cyclosporine | DDT | Deferoxamine | Dexamethasone | diallyl disulfide | Dichlorodiphenyl Dichloroethylene | Diethylstilbestrol | dihydromyricetin | Dimethoate | dioscin | Disulfiram | Docetaxel | Doxorubicin | Dronedarone | Drugs, Chinese Herbal | Epirubicin | Estradiol | Ethanol | Ethinyl Estradiol | Etoposide | fipronil | Fluorouracil | Fluoxetine | Formaldehyde | Genistein | Glutathione | glyphosate | Hydrogen Peroxide | hydroquinone | Hydroxyapatites | Hydroxyurea | Iopamidol | Isoflurane | lead acetate | Lipopolysaccharides | manganese chloride | Melatonin | Metformin | methylmercuric chloride | Methylmercury Compounds | Mifepristone | NAD | Nanotubes, Carbon | naringin | Nicotine | Oleanolic Acid | Oxcarbazepine | Oxygen | Paclitaxel | Palmitates | Particulate Matter | Permethrin | phenanthrene | Piperonyl Butoxide | Plant Extracts | Polysaccharides | Prednisone | Probenecid | pyrene | Quercetin | Raloxifene Hydrochloride | Resveratrol | Ribavirin | Rosiglitazone | Rotenone | Rutin | SB 203580 | Selenium | Sertraline | Simvastatin | sodium arsenate | sodium arsenite | Sodium Selenite | Spironolactone | sulforafan | Tacrolimus | Tamoxifen | tangeretin | Tea | Tetrachlorodibenzodioxin | tetrathiomolybdate | triptolide | U 0126 | ursolic acid | Valproic Acid | Vincristine | Vitamin E | Zearalenone | Zidovudine Inferred via 23 genes: ABI1 | BAX | CTNNB1 | CXCL1 | EIF2AK1 | HMOX1 | IFNG | IGF1 | IL1A | IL1B | IL6 | MIR21 | MIR218-1 | MIR221 | MIR29B2 | MIR29C | NOX4 | PLG | PTGS2 | S100A11 | SOD2 | SULT2B1 | TNF 980
33. ATP biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 113 chemicals: 3-(5-(2,3-dichlorophenyl)-1H-tetrazol-1-yl)methylpyridine | 4,4'-hexafluorisopropylidene diphenol | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | 4-phenylbutyric acid | 6-formylindolo(3,2-b)carbazole | Acetaminophen | alpha-naphthoflavone | Aluminum Oxide | Amodiaquine | Arsenic Trioxide | arsenite | Atorvastatin | Axitinib | Benzbromarone | Berberine | bisphenol A | Bupropion | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | ceric oxide | Chlorpromazine | Cisplatin | Clotrimazole | Clozapine | coenzyme Q10 | Copper Sulfate | Crizotinib | Curcumin | cyanoginosin LR | cylindrospermopsin | cyproconazole | Dacarbazine | decamethrin | Deoxycholic Acid | Dichlorvos | Dietary Fats | Diethylstilbestrol | Diquat | Doxorubicin | dysprosium oxide | epigallocatechin gallate | erbium oxide | Erlotinib Hydrochloride | Ethanol | Etoposide | Fenofibrate | Flutamide | gadolinium chloride | gadolinium oxide | Gefitinib | Glafenine | Glyburide | Haloperidol | hexabromocyclododecane | Hydrogen Peroxide | Imatinib Mesylate | INCB018424 | Isoniazid | Ketoconazole | Ketoprofen | lanthanum oxide | Lapatinib | lead acetate | Leflunomide | Levofloxacin | Limonene | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Metformin | Nanotubes, Carbon | nefazodone | neodymium oxide | Niacinamide | ochratoxin A | Oxygen | Paraquat | perfluorooctane sulfonic acid | pimagedine | piperine | Plant Extracts | Proadifen | puerarin | pyrazolanthrone | Pyruvaldehyde | Quercetin | Resveratrol | Rifampin | Risperidone | Rosiglitazone | Rotenone | samarium oxide | Simvastatin | Sorafenib | Streptozocin | Tapentadol | Taurocholic Acid | tert-Butylhydroperoxide | tetrathiomolybdate | Thioctic Acid | Ticlopidine | titanium dioxide | Tramadol | triptolide | Troglitazone | trovafloxacin | uranyl acetate | usnic acid | Valproic Acid | Vitamin E | Zearalenone | Zinc Inferred via 1 gene: CKB 1053
34. positive regulation of glutathione peroxidase activity Chemical and Drug Induced Liver Injury Inferred via 110 chemicals: 4-nitrophenol | Acetaminophen | Acetylcarnitine | Acetylcysteine | Acrylamide | allicin | Aluminum Chloride | Amlodipine | aroclor 1260 | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | barium chloride | Benzo(a)pyrene | beta Carotene | Biflavonoids | bisphenol A | Cadmium Chloride | Carbon Tetrachloride | Carvedilol | Cholesterol | Cisplatin | Clotrimazole | cobaltous chloride | coenzyme Q10 | Copper | Copper Sulfate | Curcumin | Cyclophosphamide | cyfluthrin | cylindrospermopsin | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylnitrosamine | Dihydralazine | diphenyldiselenide | eleostearic acid | Environmental Pollutants | epigallocatechin gallate | Estradiol | Ethanol | Etoposide | Eugenol | Folic Acid | Genistein | Glutathione | Glyburide | Hydrogen Peroxide | Iron | lead acetate | lead chloride | lead nitrate | Lipids | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lutein | Lycopene | Maneb | Melatonin | Mercuric Chloride | Mercury | Methotrexate | methylmercuric chloride | Nanotubes, Carbon | naringin | nickel sulfate | ochratoxin A | oxymatrine | Paraquat | Penicillamine | perfluorododecanoic acid | Perindopril | phenanthrene | Phycocyanin | Plant Extracts | Polysaccharides | Porphyrins | potassium bromate | Potassium Dichromate | Propolis | puerarin | punicic acid | Pyruvaldehyde | Quercetin | Resveratrol | Rosiglitazone | Selenium | sesamin | sodium arsenate | sodium arsenite | Sodium Fluoride | Sodium Nitrite | Sodium Selenite | Streptozocin | Taurine | tetrahydrocurcumin | Thallium | Thioacetamide | Thioctic Acid | Thiophanate | thymoquinone | titanium dioxide | triphenyl phosphate | vanillin | Vincristine | Vitamin E | Zearalenone | Zinc   1035
35. glutathione transferase activity Chemical and Drug Induced Liver Injury Inferred via 108 chemicals: 1,2-Dimethylhydrazine | 2,2',4,4',5-brominated diphenyl ether | 2,2',4,4'-tetrabromodiphenyl ether | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrylamide | Aflatoxin B1 | alachlor | Alloxan | Aluminum Oxide | Amoxicillin | andrographolide | Apigenin | Arsenic | Arsenic Trioxide | Ascorbic Acid | Atrazine | Benzo(a)pyrene | bifendate | bisphenol A | Buprenorphine | Butylated Hydroxyanisole | Cadmium | Cadmium Chloride | Carbon Tetrachloride | Carvedilol | Chlorpyrifos | Cisplatin | cobaltous chloride | Copper | Copper Sulfate | coumarin | Curcumin | Cyclophosphamide | decabromobiphenyl ether | Dexamethasone | diallyl disulfide | Dichlorvos | Dietary Fats | diethyl maleate | Diethylnitrosamine | diosbulbin B | diphenyldiselenide | Doxorubicin | Drugs, Chinese Herbal | Endosulfan | Ethanol | Ethylene Dibromide | Eugenol | fipronil | Fluorouracil | Galactosamine | Glyburide | glyphosate | Grape Seed Proanthocyanidins | hesperetin | Hesperidin | Isoniazid | lead acetate | Lipopolysaccharides | Lycopene | Malathion | manganese chloride | mangiferin | Mercuric Chloride | Methylene Chloride | Methylmercury Compounds | naringenin | naringin | oltipraz | Oxygen | Permethrin | Phenobarbital | Plant Extracts | Plant Preparations | Polysaccharides | potassium bromate | Potassium Dichromate | Quercetin | Resveratrol | Rotenone | Selenium | Silver | Silymarin | sodium arsenite | Sodium Fluoride | Sodium Selenite | Streptozocin | sulforafan | Taurine | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | Thyroxine | titanium dioxide | triphenyl phosphate | uranyl acetate | Vehicle Emissions | Vitamin A | Vitamin E | Zearalenone | Zinc | zinc chloride | Zinc Oxide | zingerone Inferred via 8 genes: GSTA4 | GSTM1 | GSTM2 | GSTM3 | GSTM4 | GSTO1 | GSTP1 | GSTT1 1134
36. triglyceride biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 108 chemicals: 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | Acetylcysteine | Aflatoxin B1 | Allopurinol | almond oil | alpha-Tocopherol | Amiodarone | Arsenic Trioxide | Atazanavir Sulfate | Atorvastatin | Betaine | Bezafibrate | bisphenol A | Cadmium | Cadmium Chloride | Carbon Tetrachloride | Chenodeoxycholic Acid | Cholesterol | Cholesterol, Dietary | Choline | cobaltous chloride | coenzyme Q10 | Copper | Copper Sulfate | Curcumin | cyproconazole | Dexamethasone | Dextromethorphan | Dietary Fats | Dietary Sucrose | Diethylhexyl Phthalate | Diethylnitrosamine | Diethylstilbestrol | diphenyldiselenide | Doxorubicin | Erythromycin | Ethanol | ethylene dichloride | Fatty Acids | Fenofibrate | Ficusin | fipronil | Fish Oils | Fluvastatin | Folic Acid | Fructose | gadolinium chloride | glimepiride | Glyburide | Grape Seed Proanthocyanidins | Hesperidin | hexabromocyclododecane | imidacloprid | Indomethacin | Isoniazid | Lovastatin | mangiferin | Mercuric Chloride | Metformin | Methimazole | Methionine | Methylmercury Compounds | naringenin | naringin | Niacin | Nicotine | Oxygen | Palmitates | Particulate Matter | Penicillin G | perfluorooctanoic acid | Permethrin | Pioglitazone | piperine | Plant Extracts | Plant Preparations | Polysaccharides | potassium chromate(VI) | Potassium Dichromate | Propolis | puag-haad | Pyrazinamide | Quercetin | Resveratrol | Ritonavir | Rosiglitazone | Rutin | Salicylic Acid | salvianolic acid B | Saquinavir | Selenium | Silybin | sodium arsenate | sodium arsenite | Streptozocin | Tapentadol | Telmisartan | tetrabromobisphenol A | Tetrachlorodibenzodioxin | Tetrachloroethylene | Thioacetamide | triphenyl phosphate | ursolic acid | Valproic Acid | Vitamin B 12 | Zearalenone | Zidovudine | zingerone Inferred via 2 genes: ACSL1 | DGAT2 927
37. L-aspartate:2-oxoglutarate aminotransferase activity Chemical and Drug Induced Liver Injury Inferred via 100 chemicals: 1,2,4-triazole | 18alpha-glycyrrhetinic acid | 1-Naphthylisothiocyanate | 4-phenylbutyric acid | 6-methyl-2-(phenylethynyl)pyridine | Acetaminophen | Acetylcysteine | Alloxan | almond oil | alpha-Tocopherol | Aluminum Chloride | Ascorbic Acid | Atrazine | bisphenol A | Cadmium Chloride | caffeic acid | canadine | Carbon Tetrachloride | Chlorogenic Acid | chloroquine diphosphate | Choline | Cimetidine | Cisplatin | Curcumin | cyanoginosin LR | Cyclophosphamide | Cyclosporine | Dexamethasone | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | dihydromyricetin | Dimethyl Sulfoxide | diphenyldiselenide | Doxorubicin | Drugs, Chinese Herbal | Ethanol | Ethinyl Estradiol | ethylene dichloride | Ficusin | Fluorouracil | Fructose | fumonisin B1 | Fungal Polysaccharides | Galactosamine | Genistein | Glyburide | Glycyrrhizic Acid | Hesperidin | hexabromocyclododecane | Isoniazid | Lead | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Malathion | mangiferin | Melatonin | Mesalamine | Metformin | Methapyrilene | Methionine | Methotrexate | Monocrotaline | naringenin | Niacinamide | octamethylcyclotetrasiloxane | Orlistat | Permethrin | Phenobarbital | Pioglitazone | piperine | pirinixic acid | Plant Extracts | Poloxamer | propacetamol | Propolis | Propoxur | Quercetin | Resveratrol | retrorsine | Rutin | salvianolic acid B | Silver | Silybin | Silymarin | Streptozocin | Tapentadol | tert-Butylhydroperoxide | Thiamethoxam | Thioacetamide | thymoquinone | titanium dioxide | Tramadol | tri-o-cresyl phosphate | Ursodeoxycholic Acid | ursolic acid | Vitamin E | Zidovudine | Zinc Oxide Inferred via 1 gene: GOT1 1140
38. superoxide anion generation Chemical and Drug Induced Liver Injury Inferred via 98 chemicals: 2,3-dimethoxy-1,4-naphthoquinone | 3-methylquercetin | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Acrolein | Adenosine Triphosphate | Aflatoxin B1 | Alloxan | Aluminum Chloride | Arsenic Trioxide | Ascorbic Acid | Benzo(a)pyrene | Berberine | bisphenol A | Bupropion | Cadmium Chloride | Carbon Tetrachloride | ceric oxide | cerous chloride | chelerythrine | chromium hexavalent ion | Ciprofloxacin | Cisplatin | cupric chloride | Curcumin | Cyclosporine | decamethrin | Dietary Fats | Diethylstilbestrol | Diosmin | Ditiocarb | Doxorubicin | Epirubicin | Estradiol | Ethanol | ferric chloride | Fish Oils | Flame Retardants | fumonisin B1 | Halogenated Diphenyl Ethers | Hesperidin | Hydrogen Peroxide | Indomethacin | Iron-Dextran Complex | isoliquiritigenin | Lead | lead acetate | Limonene | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Losartan | Maneb | manganese chloride | Melatonin | Methylmercury Compounds | MitoTEMPO | morin | Nanotubes, Carbon | naringin | nefazodone | Nickel | nickel chloride | Oleanolic Acid | Oxygen | Paraquat | Particulate Matter | Permethrin | pimagedine | potassium bromate | Propofol | pyrazolanthrone | Pyruvaldehyde | Quercetin | Resveratrol | Rifampin | Rosiglitazone | Rotenone | sesamin | Silver | sodium arsenite | Sodium Fluoride | Spironolactone | Streptozocin | sulforafan | Tamoxifen | tangeretin | Taurine | tauroursodeoxycholic acid | tert-Butylhydroperoxide | tetrahydrocurcumin | Thioctic Acid | titanium dioxide | vanillin | Vehicle Emissions | Vitamin A | Vitamin E | Vitamin K 3 Inferred via 3 genes: NOX4 | SOD1 | SOD2 941
39. cholesterol biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 96 chemicals: 1-Naphthylisothiocyanate | Acetylcysteine | Aflatoxin B1 | Allopurinol | alpha-Linolenic Acid | alpha-Tocopherol | Amiodarone | Atazanavir Sulfate | Atorvastatin | Bezafibrate | bisphenol A | Cadmium | Cadmium Chloride | Carbon Tetrachloride | Catechin | Chenodeoxycholic Acid | Cholesterol | Cholesterol, Dietary | Choline | Clofibrate | coenzyme Q10 | Curcumin | cyproconazole | Dexamethasone | Dextromethorphan | Dietary Fats | Dietary Sucrose | Diethylnitrosamine | Dimethoate | Donepezil | Drugs, Chinese Herbal | Ethanol | Ficusin | Fish Oils | Fluvastatin | Fructose | Galactosamine | Glyburide | Haloperidol | Hesperidin | hexabromocyclododecane | imidacloprid | Isoniazid | lead acetate | lead nitrate | Lipopolysaccharides | Lovastatin | mangiferin | Mercuric Chloride | Metformin | Methimazole | Methionine | Methylmercury Compounds | Mifepristone | naringenin | naringin | Niacin | Nicotine | Particulate Matter | perfluorooctane sulfonic acid | perfluorooctanoic acid | Pioglitazone | piperine | Plant Extracts | Plant Preparations | Pravastatin | prochloraz | Propolis | Quercetin | Resveratrol | Ritonavir | Rosiglitazone | Rutin | Salicylic Acid | salvianolic acid B | Saquinavir | Selenium | Silver | Silybin | Simvastatin | sodium arsenate | sodium arsenite | Streptozocin | Tapentadol | Telmisartan | Tetrachlorodibenzodioxin | Tetracycline | Thiamethoxam | Thioacetamide | thymoquinone | Tramadol | triphenyl phosphate | ursolic acid | Vehicle Emissions | Zidovudine | zingerone Inferred via 1 gene: APOA1 877
40. leukocyte migration involved in inflammatory response Chemical and Drug Induced Liver Injury Inferred via 95 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | 4-phenylbutyric acid | Acetaminophen | Acetylcysteine | allyl methyl disulfide | alpha-Tocopherol | aroclor 1260 | Arsenic Trioxide | bisphenol A | Carbon Tetrachloride | Carnosine | Cholic Acid | Choline | Cimetidine | cinnabar | Cisplatin | corosolic acid | Curcumin | cyanoginosin LR | Cyclosporine | decamethrin | Dexamethasone | Diclofenac | Dietary Fats | Diethylnitrosamine | dihydromyricetin | Dimethylformamide | diphenyldiselenide | Doxorubicin | Drugs, Chinese Herbal | Emodin | epigallocatechin gallate | Ethanol | Famotidine | Floxacillin | Fructose | Galactosamine | Glyburide | Grape Seed Extract | Grape Seed Proanthocyanidins | HFPO4 compound | hydroquinone | Hydroxyapatites | imidacloprid | Indomethacin | Lansoprazole | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Melatonin | Metformin | Methapyrilene | Methionine | Monocrotaline | naringin | Nickel | nickel chloride | Oleanolic Acid | Omeprazole | Oxygen | Ozone | Paraquat | Particulate Matter | perfluorooctanoic acid | Plant Extracts | Polylactic Acid-Polyglycolic Acid Copolymer | Quercetin | Resveratrol | Rutin | salvianolic acid B | Saponins | SB 657510 | Silybin | Smoke | Sodium Nitrite | Sodium Selenite | Streptozocin | Tamoxifen | Tapentadol | Taurine | Telmisartan | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | titanium dioxide | Tramadol | Trichloroethylene | tris(1,3-dichloro-2-propyl)phosphate | tris(2,3-dibromopropyl)isocyanurate | ursolic acid | Vehicle Emissions | Vitamin E | Zinc | zingerone Inferred via 2 genes: ADAM8 | CCL2 1024
41. alkaline phosphatase activity Chemical and Drug Induced Liver Injury Inferred via 94 chemicals: 18alpha-glycyrrhetinic acid | 1-Naphthylisothiocyanate | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 9,10-Dimethyl-1,2-benzanthracene | Acetaminophen | Acetylcysteine | Allopurinol | Alloxan | alpha-Tocopherol | Aluminum Chloride | Arsenic Trioxide | Ascorbic Acid | bisphenol A | Cadmium Chloride | caraway oil | Carbon Tetrachloride | Chenodeoxycholic Acid | Cisplatin | Curcumin | cyanoginosin LR | Cyclophosphamide | Cyclosporine | decabromobiphenyl ether | decamethrin | Deoxycholic Acid | Dexamethasone | Diclofenac | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | dihydromyricetin | Dimethylnitrosamine | Dimethyl Sulfoxide | diosbulbin B | dioscin | diphenyldiselenide | Doxorubicin | Endosulfan | Ethanol | Ethinyl Estradiol | Ficusin | Fluorouracil | Fructose | Fungal Polysaccharides | Glyburide | Glycyrrhizic Acid | Halogenated Diphenyl Ethers | Hesperidin | hexabromocyclododecane | Hydrogen Peroxide | Isoniazid | Lead | Malathion | manganese chloride | Mercuric Chloride | Metformin | Methapyrilene | Methotrexate | naringenin | naringin | Niacinamide | Nickel | nickel sulfate | pentabromodiphenyl ether | Phenobarbital | Pioglitazone | Plant Extracts | pyrazolanthrone | Quercetin | Resveratrol | SB 203580 | Selenium | Silver | Silybin | Silymarin | sodium arsenite | Sodium Fluoride | Streptozocin | Tea | Telmisartan | Tetrachlorodibenzodioxin | Thiamethoxam | Thioacetamide | thymoquinone | titanium dioxide | triphenyl phosphate | troxerutin | Ursodeoxycholic Acid | Vitamin E | Warfarin | Zidovudine | Zinc | Zinc Oxide | Zinc Sulfate   1151
42. lactate dehydrogenase activity Chemical and Drug Induced Liver Injury Inferred via 89 chemicals: 18alpha-glycyrrhetinic acid | Acetaminophen | Acetylcysteine | Acrylamide | Alloxan | allyl methyl disulfide | allyl sulfide | alpha-Tocopherol | Aluminum Chloride | Amoxicillin | Arsenic Trioxide | Ascorbic Acid | Atorvastatin | Atrazine | Benzo(a)pyrene | bisphenol A | Buprenorphine | Cadmium | Cadmium Chloride | Carbon Tetrachloride | Chlorogenic Acid | chloroquine diphosphate | Chlorpyrifos | Cimetidine | Cisplatin | Clofibrate | Clozapine | coenzyme Q10 | Copper Sulfate | Curcumin | decabromobiphenyl ether | Dexamethasone | Dichlorodiphenyl Dichloroethylene | Dietary Fats | Diethylhexyl Phthalate | Diethylnitrosamine | dihydromyricetin | dimethyl mercury | Dimethylnitrosamine | Dimethyl Sulfoxide | diphenyldiselenide | Doxorubicin | Dust | epigallocatechin gallate | Ethanol | Fluorouracil | Fomepizole | Grape Seed Extract | Grape Seed Proanthocyanidins | Hesperidin | lipopolysaccharide, E coli O55-B5 | Lipopolysaccharides | Malathion | manganese chloride | Mercuric Chloride | Metformin | Methionine | Methotrexate | NAD | naringin | Niacinamide | Nickel | nickel sulfate | ochratoxin A | octamethylcyclotetrasiloxane | Oxygen | Paraquat | Plant Extracts | potassium bromate | Potassium Dichromate | Quercetin | Resveratrol | Rutin | Selenium | Silver | sodium arsenite | Sodium Selenite | Streptozocin | Tapentadol | Thiamethoxam | Thioacetamide | Thioctic Acid | titanium dioxide | Tramadol | troxerutin | vanillin | Venlafaxine Hydrochloride | Zinc | Zinc Oxide   1006
43. cell growth Chemical and Drug Induced Liver Injury Inferred via 89 chemicals: 3,4,5,3',4'-pentachlorobiphenyl | Acetylcysteine | Aflatoxin B1 | Allopurinol | allyl sulfide | Amodiaquine | Amoxicillin | Ampicillin | Arsenic Trioxide | Ascorbic Acid | baicalein | Benzbromarone | bisphenol A | Buthionine Sulfoximine | Butylated Hydroxyanisole | Butylated Hydroxytoluene | Cadmium Chloride | Carbamazepine | Catechin | Chloroquine | Chlorpyrifos | Cisplatin | Cocaine | Cyclosporine | Daunorubicin | decamethrin | deoxynivalenol | Dexamethasone | Dichloroacetic Acid | Diclofenac | Doxorubicin | Drugs, Chinese Herbal | Emodin | epigallocatechin gallate | Estradiol | Ethanol | Ethinyl Estradiol | Eugenol | Fluorouracil | Fluoxetine | Flutamide | germacrone | Glutathione | Grape Seed Extract | Hemin | Hyaluronic Acid | Hydrogen Peroxide | Imatinib Mesylate | Ketoconazole | Ketoprofen | Levofloxacin | manganese chloride | Mebendazole | Mercuric Chloride | Methamphetamine | Methotrexate | Nanotubes, Carbon | Oxygen | Paclitaxel | Particulate Matter | perfluorooctane sulfonic acid | perfluorooctanoic acid | Plant Extracts | Plant Oils | Plant Preparations | Propranolol | Resveratrol | Rotenone | senecionine | Silver | sodium arsenite | Sodium Fluoride | Tapentadol | tauroursodeoxycholic acid | tert-Butylhydroperoxide | Thioacetamide | thymoquinone | titanium dioxide | Tramadol | triptolide | Troglitazone | trovafloxacin | U 0126 | Valproic Acid | Venlafaxine Hydrochloride | Verapamil | Vincristine | zinc protoporphyrin | Zinc Sulfate   784
44. cell migration Chemical and Drug Induced Liver Injury Inferred via 87 chemicals: 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 6-formylindolo(3,2-b)carbazole | Acetylcysteine | alpha-Linolenic Acid | alpha-naphthoflavone | andrographolide | Apigenin | Arsenic | Arsenic Trioxide | baicalein | Benzo(a)pyrene | beta Carotene | BIRB 796 | bisphenol A | Cadmium | Cadmium Chloride | Carbamazepine | Carbon Tetrachloride | Catechin | Celecoxib | Chlorambucil | Clozapine | cobaltous chloride | Copper | cupric chloride | Curcumin | cyanoginosin LR | Dexamethasone | diallyl trisulfide | Dichlorodiphenyl Dichloroethylene | Dietary Fats | dioscin | Docetaxel | Doxorubicin | Drugs, Chinese Herbal | epigallocatechin gallate | Estradiol | Ethanol | Eugenol | Fluorouracil | Genistein | Hesperidin | hydroquinone | Imatinib Mesylate | imidacloprid | INCB018424 | Indomethacin | Lipopolysaccharides | Mebendazole | Metformin | Mifepristone | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | naringenin | naringin | nickel chloride | nickel sulfate | Oleanolic Acid | Oxygen | Paclitaxel | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | perfluorooctanoic acid | Phenytoin | Plant Extracts | Pregnenolone Carbonitrile | Progesterone | pyrazolanthrone | Quercetin | Resveratrol | Rutin | SB 203580 | Smoke | sodium arsenite | Sorafenib | sulforafan | Taurocholic Acid | Temozolomide | Tetrachlorodibenzodioxin | Thiram | thymoquinone | Thyroxine | triptolide | U 0126 | Valproic Acid | zileuton | Zinc Oxide Inferred via 4 genes: FLT1 | MMP2 | SORL1 | VEGFA 781
45. cell differentiation Chemical and Drug Induced Liver Injury Inferred via 86 chemicals: 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | Acetylcysteine | Alitretinoin | Androgens | Arsenic Trioxide | Aspirin | Atorvastatin | Auranofin | Azacitidine | bisphenol A | Bortezomib | caffeic acid | Capsaicin | Carmustine | chelerythrine | Chloramphenicol | Chloroquine | Clotrimazole | Clozapine | Cocaine | Colchicine | Curcumin | Cyclophosphamide | Cyproterone Acetate | Cytarabine | Dactinomycin | Dasatinib | Deferoxamine | Dexamethasone | Diclofenac | Diethylstilbestrol | Digoxin | Dimethyl Sulfoxide | efavirenz | Estradiol | Ethanol | Etoposide | Flutamide | Gefitinib | Genistein | Glucocorticoids | Heparin | Hydroxyurea | Indinavir | Indomethacin | Lipopolysaccharides | Lithium | Lovastatin | Lutein | Medroxyprogesterone Acetate | Melatonin | Metformin | Morphine | Naltrexone | Nevirapine | Nicotine | nimesulide | Octreotide | Omeprazole | Oxygen | Paclitaxel | Pentoxifylline | pimagedine | Plant Extracts | potassium bromate | Progesterone | Quercetin | Quinidine | Quinine | Reactive Oxygen Species | Resveratrol | rofecoxib | Rosiglitazone | SB 203580 | Simvastatin | Sodium Selenite | Tacrolimus | Tetrachlorodibenzodioxin | Thalidomide | Tretinoin | tributyrin | Triiodothyronine | U 0126 | Valproic Acid | Vitamin A | Vitamin E Inferred via 9 genes: ARNT | ATOH8 | CTNNB1 | LGALS3 | PTF1A | PUM1 | SPP1 | TGFBR1 | VEGFA 725
46. positive regulation of p38MAPK cascade Chemical and Drug Induced Liver Injury Inferred via 85 chemicals: 1,3-dichloro-2-propanol | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 2''-galloylhyperin | 6-formylindolo(3,2-b)carbazole | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetylcysteine | Acrylamide | Adenosine Triphosphate | alpha-naphthoflavone | Aluminum | andrographolide | Apigenin | Arsenic Trioxide | Ascorbic Acid | Benzo(a)pyrene | bisphenol A | Blood Glucose | Cadmium | Cadmium Chloride | Chlorpyrifos | Cholesterol | Cisplatin | Clotrimazole | cobaltous chloride | Cocaine | Copper | Curcumin | cyanoginosin LR | Dexamethasone | Dietary Fats | Disulfiram | Doxorubicin | Drugs, Chinese Herbal | Estradiol | Ethanol | Folic Acid | Galactosamine | Gefitinib | Genistein | Hydrogen Peroxide | lead acetate | Lipids | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | Lovastatin | magnolol | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Methotrexate | methylmercuric chloride | N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide | naringenin | nefazodone | nickel sulfate | nodularin | ochratoxin A | Oxygen | Paclitaxel | Paraquat | Particulate Matter | perfluorooctane sulfonic acid | Phytochemicals | Plant Extracts | Propranolol | pyrazolanthrone | Pyruvaldehyde | Quercetin | Reactive Oxygen Species | Resveratrol | Rosiglitazone | Rotenone | SB 203580 | Selenium | sodium arsenite | SRT1720 | Streptozocin | sulforafan | tert-Butylhydroperoxide | Thioctic Acid | triptolide | ursolic acid | usnic acid | Valproic Acid | Vehicle Emissions | zinc protoporphyrin Inferred via 4 genes: GADD45A | IL1B | MAP3K5 | VEGFA 711
47. positive regulation of nitric oxide biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 82 chemicals: 1,3-dichloro-2-propanol | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one | 3-methylquercetin | Acetylcysteine | Arsenic | Arsenic Trioxide | arsenite | Ascorbic Acid | Atrazine | bisphenol A | Blood Glucose | Carbamazepine | Catechin | Cisplatin | cobaltous chloride | coenzyme Q10 | Curcumin | Cyclosporine | decamethrin | Dexamethasone | diallyl trisulfide | Dietary Fats | Docetaxel | Doxorubicin | Drugs, Chinese Herbal | epigallocatechin gallate | Estradiol | Ethanol | Fluvastatin | Formaldehyde | Fructose | Genistein | Hemin | Iron-Dextran Complex | isoliquiritigenin | lead acetate | lead chloride | lipopolysaccharide, E coli O55-B5 | lipopolysaccharide, Escherichia coli O111 B4 | Lipopolysaccharides | magnolol | Mercuric Chloride | Metformin | Methylprednisolone | montelukast | naringin | nickel sulfate | Nitric Oxide | Oxygen | Paraquat | Peptides | phenanthrene | Phytochemicals | pimagedine | piperine | Plant Extracts | Poloxamer | poly(methyl vinyl ether-co-maleic anhydride) | Polysaccharides | Pregabalin | puerarin | pyrazolanthrone | Quercetin | Resveratrol | Rosiglitazone | Rotenone | SB 203580 | Sertraline | Simvastatin | sodium arsenite | Sodium Fluoride | Sodium Selenite | Streptozocin | sulforafan | Tamoxifen | Tea | tetrahydrocurcumin | Thalidomide | Thioctic Acid | thymoquinone | Vincristine | zinc protoporphyrin Inferred via 8 genes: CLU | CRP | IFNG | IL1B | IL6 | PTGS2 | SOD2 | TNF 560
48. positive regulation of apoptotic DNA fragmentation Chemical and Drug Induced Liver Injury Inferred via 79 chemicals: Acetaminophen | Acetylcysteine | Aflatoxin B1 | Allopurinol | alpha-Tocopherol | Apigenin | Arsenic | arsenic disulfide | Arsenic Trioxide | Ascorbic Acid | Aspirin | Atrazine | beta Carotene | Biological Products | bisphenol A | Blood Glucose | Buthionine Sulfoximine | Cadmium | Cadmium Chloride | Catechin | Chloroquine | Cisplatin | cobaltous chloride | Copper | Curcumin | Cycloheximide | Cyclophosphamide | Dactinomycin | decamethrin | Dexamethasone | diallyl trisulfide | Diclofenac | Ditiocarb | Doxorubicin | Drugs, Chinese Herbal | Emodin | Enalapril | erdosteine | Ethanol | Galactosamine | Hydrogen Peroxide | Indomethacin | isoliquiritigenin | Ketoconazole | lead acetate | Lipopolysaccharides | Lycopene | magnolol | manganese chloride | manganese(III)-tetrakis(4-benzoic acid)porphyrin | Methotrexate | methylmercuric chloride | MitoTEMPO | naringin | nickel chloride | Nitric Oxide | Oleanolic Acid | Oxygen | Paclitaxel | Paraquat | Particulate Matter | Plant Extracts | Polylactic Acid-Polyglycolic Acid Copolymer | pyrazolanthrone | Quercetin | Resveratrol | Rifampin | Rotenone | Rutin | Salicylic Acid | Sevoflurane | Silver | sodium arsenite | Streptozocin | Tamoxifen | Tea | TEMPO | trovafloxacin | Zinc Inferred via 1 gene: BAX 954
49. autophagy Chemical and Drug Induced Liver Injury Inferred via 78 chemicals: 4-phenylbutyric acid | 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid | Acetylcysteine | alpha-Tocopherol | Apigenin | Arsenic Trioxide | astin B | Atorvastatin | Atrazine | Bortezomib | Cadmium | Cadmium Chloride | Capsaicin | Celecoxib | Chlormethiazole | Chloroquine | chloroquine diphosphate | Cholesterol | Cisplatin | Cyclosporine | Dasatinib | Deferoxamine | Dexamethasone | Dietary Fats | Doxorubicin | Epirubicin | Erlotinib Hydrochloride | Ethanol | Fluorouracil | Fluoxetine | Gefitinib | Hydrogen Peroxide | Imatinib Mesylate | lead acetate | Lipopolysaccharides | Lithium | Maprotiline | Medroxyprogesterone Acetate | Melatonin | Metformin | Methamphetamine | Minocycline | Morphine | Nanotubes, Carbon | Nelfinavir | ochratoxin A | Oleanolic Acid | Orlistat | Oxygen | Paclitaxel | Paraquat | Pentoxifylline | Polyethylene Glycols | pyrazolanthrone | Quercetin | Reactive Oxygen Species | Resveratrol | Rifampin | Rosiglitazone | Rotenone | Saponins | Saquinavir | SB 203580 | sodium arsenite | Sodium Selenite | Sorafenib | Tamoxifen | Taurine | Temozolomide | Thalidomide | Thioctic Acid | Thioguanine | Tretinoin | tri-o-cresyl phosphate | triptolide | U 0126 | ursolic acid | Vitamin E Inferred via 4 genes: ATG5 | HMGB1 | MAP1LC3B | PARK7 502
50. lipid biosynthetic process Chemical and Drug Induced Liver Injury Inferred via 78 chemicals: 1,4-bis(2-(3,5-dichloropyridyloxy))benzene | 2,2',4,4'-tetrabromodiphenyl ether | 3,4,5,3',4'-pentachlorobiphenyl | Alcohols | Amiodarone | andrographolide | Aspirin | Azathioprine | Benzo(a)pyrene | Berberine | Bezafibrate | bisphenol A | Buthionine Sulfoximine | Chlorpropamide | Cholesterol | Clofibrate | Curcumin | Cyclosporine | cyproconazole | Deoxycholic Acid | Dexamethasone | Dietary Fats | dihydromyricetin | Dimethyl Sulfoxide | Doxorubicin | Doxycycline | Estradiol | Ethanol | Fatty Acids | Fenofibrate | Fluoxetine | Fructose | Halothane | Hesperidin | hexabromocyclododecane | Hydrogen Peroxide | isoliquiritigenin | Isoniazid | Mifepristone | myricitrin | Niacin | obeticholic acid | olmesartan | Orlistat | Palmitates | Paraquat |