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Disease Chemical and Drug Induced Liver Injury

These diseases have comparable sets of interacting chemicals and genes to Chemical and Drug Induced Liver Injury.

Via chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.24095 0.24095 386
Kidney Diseases 0.22536 0.22536 343
Acute Kidney Injury 0.1929 0.1929 277
Cholestasis 0.17866 0.17866 221
Drug-Related Side Effects and Adverse Reactions 0.17814 0.17814 264
Inflammation 0.16547 0.16547 254
Weight Loss 0.1636 0.1636 222
Hepatomegaly 0.15926 0.15926 208
Nausea 0.15484 0.15484 227
Liver Diseases 0.15166 0.15166 192
Fever 0.14829 0.14829 199
Edema 0.14587 0.14587 221
Headache 0.14538 0.14538 206
Seizures 0.14358 0.14358 284
Hypertension 0.14204 0.14204 249
Renal Insufficiency 0.142 0.142 189
Heart Diseases 0.14072 0.14072 188
Vomiting 0.139 0.139 201
Fatty Liver 0.13869 0.13869 176
Hepatitis 0.13748 0.13748 168

Via marker/mechanism chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.218 0.218 281
Kidney Diseases 0.20785 0.20785 249
Acute Kidney Injury 0.20609 0.20609 237
Cholestasis 0.19559 0.19559 195
Nausea 0.17061 0.17061 209
Drug-Related Side Effects and Adverse Reactions 0.16878 0.16878 200
Hepatomegaly 0.16823 0.16823 179
Headache 0.16102 0.16102 190
Jaundice 0.16016 0.16016 156
Hepatitis 0.15891 0.15891 157
Liver Diseases 0.15878 0.15878 161
Renal Insufficiency 0.15449 0.15449 167
Vomiting 0.15203 0.15203 180
Weight Loss 0.15171 0.15171 164
Seizures 0.15168 0.15168 221
Fever 0.15028 0.15028 162
Stevens-Johnson Syndrome 0.13683 0.13683 146
Drug Hypersensitivity 0.13188 0.13188 139
Hypertension 0.13183 0.13183 164
Edema 0.12906 0.12906 147

Via therapeutic chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.22271 0.22271 102
Kidney Diseases 0.17987 0.17987 84
Inflammation 0.13589 0.13589 78
Weight Loss 0.12401 0.12401 47
Fatty Liver 0.11831 0.11831 42
Drug-Related Side Effects and Adverse Reactions 0.11401 0.11401 48
Acute Kidney Injury 0.11194 0.11194 45
Heart Diseases 0.10554 0.10554 40
Edema 0.10506 0.10506 54
Liver Cirrhosis, Experimental 0.10263 0.10263 39
Myocardial Infarction 0.09641 0.09641 43
Proteinuria 0.09615 0.09615 40
Liver Cirrhosis 0.09605 0.09605 34
Cardiomyopathies 0.09021 0.09021 35
Carcinoma, Hepatocellular 0.0844 0.0844 33
Insulin Resistance 0.08312 0.08312 32
Hemorrhage 0.08311 0.08311 31
Neoplasms 0.07977 0.07977 41
Liver Diseases 0.07918 0.07918 27
Hypertension 0.07813 0.07813 55

Via gene associations

Similarity Index Common
Interacting
Genes
Cholestasis 0.09852 0.09852 40
Liver Cirrhosis 0.07561 0.07561 31
Myocardial Reperfusion Injury 0.07389 0.07389 30
Diabetes Mellitus, Type 2 0.06693 0.06693 34
Neoplasm Metastasis 0.066 0.066 33
Liver Cirrhosis, Alcoholic 0.0659 0.0659 23
Fatty Liver 0.06266 0.06266 25
Necrosis 0.06101 0.06101 23
Drug-Related Side Effects and Adverse Reactions 0.06037 0.06037 23
Hypertension 0.05964 0.05964 30
Liver Neoplasms, Experimental 0.0595 0.0595 26
Liver Cirrhosis, Experimental 0.0564 0.0564 63
Inflammation 0.05405 0.05405 24
Acute Kidney Injury 0.05385 0.05385 21
Lung Neoplasms 0.05253 0.05253 28
Breast Neoplasms 0.04967 0.04967 38
Hypersensitivity 0.04627 0.04627 18
Hepatitis B 0.04494 0.04494 16
Heart Failure 0.04481 0.04481 19
Arthritis, Rheumatoid 0.04462 0.04462 22

Via marker/mechanism gene associations

Via therapeutic gene associations

Similarity Index Common
Interacting
Genes
Liver Diseases 0.10714 0.10714 3
Liver Neoplasms 0.09091 0.09091 3
Hypertension 0.08163 0.08163 4
Vascular System Injuries 0.08 0.08 2
Liver Cirrhosis, Experimental 0.07843 0.07843 4
Soft Tissue Neoplasms 0.07692 0.07692 2
Hyperplasia 0.07407 0.07407 2
Cholestasis 0.07143 0.07143 2
Weight Loss 0.07143 0.07143 2
Carcinoma, Transitional Cell 0.06897 0.06897 2
Pulmonary Edema 0.06897 0.06897 2
Colitis 0.06667 0.06667 2
Urinary Bladder Neoplasms 0.06667 0.06667 2
Amnesia 0.06061 0.06061 2
Fibrosis 0.06061 0.06061 2
Heart Failure 0.06061 0.06061 2
Pulmonary Fibrosis 0.06061 0.06061 2
Colonic Neoplasms 0.05882 0.05882 2
Kidney Diseases 0.05882 0.05882 2
Drug-Related Side Effects and Adverse Reactions 0.05714 0.05714 2
Insulin Resistance 0.05714 0.05714 2