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Disease Chemical and Drug Induced Liver Injury

These diseases have comparable sets of interacting chemicals and genes to Chemical and Drug Induced Liver Injury.

Via chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.2454 0.2454 400
Kidney Diseases 0.22323 0.22323 346
Acute Kidney Injury 0.19097 0.19097 279
Drug-Related Side Effects and Adverse Reactions 0.17737 0.17737 268
Cholestasis 0.17563 0.17563 222
Weight Loss 0.16905 0.16905 236
Hepatomegaly 0.16667 0.16667 222
Inflammation 0.16613 0.16613 260
Nausea 0.15282 0.15282 228
Liver Diseases 0.1505 0.1505 194
Fever 0.14788 0.14788 202
Edema 0.14748 0.14748 228
Headache 0.14444 0.14444 208
Seizures 0.14407 0.14407 289
Renal Insufficiency 0.14317 0.14317 194
Fatty Liver 0.14143 0.14143 184
Hypertension 0.14109 0.14109 251
Heart Diseases 0.13783 0.13783 188
Vomiting 0.13723 0.13723 202
Hepatitis 0.13563 0.13563 169

Via marker/mechanism chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.22027 0.22027 289
Kidney Diseases 0.20608 0.20608 251
Acute Kidney Injury 0.20462 0.20462 239
Cholestasis 0.19291 0.19291 196
Hepatomegaly 0.17837 0.17837 193
Drug-Related Side Effects and Adverse Reactions 0.16944 0.16944 204
Nausea 0.16801 0.16801 209
Weight Loss 0.15913 0.15913 176
Headache 0.1586 0.1586 190
Jaundice 0.15726 0.15726 156
Hepatitis 0.15721 0.15721 158
Liver Diseases 0.15601 0.15601 161
Renal Insufficiency 0.15574 0.15574 171
Seizures 0.15108 0.15108 223
Vomiting 0.15046 0.15046 181
Fever 0.14872 0.14872 163
Stevens-Johnson Syndrome 0.13456 0.13456 146
Hypertension 0.13064 0.13064 165
Fatty Liver 0.1301 0.1301 134
Drug Hypersensitivity 0.12966 0.12966 139

Via therapeutic chemical associations

Similarity Index Common
Interacting
Chemicals
Necrosis 0.22863 0.22863 107
Kidney Diseases 0.18201 0.18201 87
Inflammation 0.14188 0.14188 83
Weight Loss 0.12911 0.12911 51
Fatty Liver 0.12162 0.12162 45
Liver Cirrhosis, Experimental 0.11568 0.11568 45
Acute Kidney Injury 0.11436 0.11436 47
Drug-Related Side Effects and Adverse Reactions 0.11316 0.11316 49
Edema 0.11195 0.11195 59
Heart Diseases 0.10825 0.10825 42
Proteinuria 0.09836 0.09836 42
Liver Cirrhosis 0.09783 0.09783 36
Myocardial Infarction 0.0967 0.0967 44
Cardiomyopathies 0.09023 0.09023 36
Hyperglycemia 0.08852 0.08852 37
Hemorrhage 0.08616 0.08616 33
Neoplasms 0.08238 0.08238 43
Carcinoma, Hepatocellular 0.08209 0.08209 33
Insulin Resistance 0.0806 0.0806 32
Memory Disorders 0.08036 0.08036 36

Via gene associations

Similarity Index Common
Interacting
Genes
Cholestasis 0.08316 0.08316 40
Liver Cirrhosis 0.07469 0.07469 36
Drug-Related Side Effects and Adverse Reactions 0.07021 0.07021 33
Myocardial Reperfusion Injury 0.06472 0.06472 31
Acute Kidney Injury 0.06263 0.06263 30
Neoplasm Metastasis 0.06122 0.06122 36
Fatty Liver 0.06054 0.06054 29
Liver Cirrhosis, Experimental 0.05907 0.05907 70
Diabetes Mellitus, Type 2 0.0567 0.0567 33
Hypertension 0.05354 0.05354 31
Pulmonary Fibrosis 0.05285 0.05285 25
Lung Neoplasms 0.05271 0.05271 34
Inflammation 0.05212 0.05212 27
Necrosis 0.05088 0.05088 23
Liver Neoplasms, Experimental 0.05068 0.05068 26
Breast Neoplasms 0.05035 0.05035 43
Liver Cirrhosis, Alcoholic 0.04953 0.04953 21
Carcinoma, Hepatocellular 0.04785 0.04785 30
Obesity 0.04754 0.04754 27
Pancreatitis 0.04646 0.04646 21

Via marker/mechanism gene associations

Via therapeutic gene associations

Similarity Index Common
Interacting
Genes
Liver Diseases 0.1 0.1 3
Fibrosis 0.08824 0.08824 3
Liver Neoplasms 0.08571 0.08571 3
Hypertension 0.07843 0.07843 4
Liver Cirrhosis, Experimental 0.07547 0.07547 4
Vascular System Injuries 0.07407 0.07407 2
Soft Tissue Neoplasms 0.07143 0.07143 2
Hyperplasia 0.06897 0.06897 2
Cholestasis 0.06667 0.06667 2
Weight Loss 0.06667 0.06667 2
Carcinoma, Transitional Cell 0.06452 0.06452 2
Pulmonary Edema 0.06452 0.06452 2
Colitis 0.0625 0.0625 2
Urinary Bladder Neoplasms 0.0625 0.0625 2
Amnesia 0.05714 0.05714 2
Heart Failure 0.05714 0.05714 2
Colonic Neoplasms 0.05556 0.05556 2
Drug-Related Side Effects and Adverse Reactions 0.05405 0.05405 2
Insulin Resistance 0.05405 0.05405 2
Kidney Diseases 0.05405 0.05405 2
Pulmonary Fibrosis 0.05405 0.05405 2