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Disease Chemically-Induced Disorders

These are exposure studies associated with the disease and all of its children.

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1–39 of 39 results.
  Reference Associated Study Title Author's Summary Study Factors Stressor Receptors Country Medium Exposure Marker Measurements Outcome
1. Mi T, et al. (2013). We describe two cases of acute toxic leukoencephalopathy in migrant workers who were occupationally exposed to organic solvents in construction materials. 1,2,3-trichloropropane | Solvents | Toluene Workers China blood | urine 1,2,3-trichloropropane | Benzoic Acid Details Leukoencephalopathies | Neurotoxicity Syndromes | Occupational Diseases
2. No authors listed. (2000). This report describes the five deaths associated with 2,4-DCP exposure (presented in the order in which they were identified) and provides recommendations for preventing additional deaths. 2,4-dichlorophenol Workers France|United Kingdom|
United States
bile | blood | serum | stomach | urine 2,4-dichlorophenol Details Acute Disease | Burns, Chemical | Death | Poisoning | Seizures
3. Kaye JA, et al. (2014). The results support a comparatively high adjusted relative risk of liver injury among patients exposed concurrently to multiple antimicrobials and modest elevations in the risk for several antimicrobials used alone; however, we found little evidence of any strong effect of commonly used antimicrobials on the risk of liver injury. Amoxicillin | Anti-Infective Agents | Clavulanic Acid | Doxycycline | Levofloxacin | Moxifloxacin Study subjects United States Details Chemical and Drug Induced Liver Injury
4. Pi J, et al. (2005). A 13-month arsenic exposure reduction effectively reverses the arsenic-induced impairment of the nitric oxide/cyclic guanosine 3',5'-monophosphate pathway in both males and females and improves peripheral vascular function in males. Arsenic Study subjects China blood | urine | water Arsenic | Cyclic GMP Details Arsenic Poisoning | Vascular Diseases
5. Ma L, et al. (2016). We reveal that specific histone modifications are associated with arsenic exposure and oxidative damage, and persistent dysregulation of these histone modifications could be a potential biomarker that evaluates the burden of arsenic exposure and predicts the adverse biological effects. Arsenic Study subjects China hair | lymphocyte | plasma | urine 8-oxo-7-hydrodeoxyguanosine | Arsenic | Malondialdehyde Details Arsenic Poisoning | positive regulation of histone H3-K14 acetylation | positive regulation of histone H3-K18 acetylation | positive regulation of histone H3-K36 trimethylation | positive regulation of histone H3-K9 dimethylation
6. Sampayo-Reyes A, et al. (2010). Altogether, our results evidenced that people living in arsenic-contaminated areas are at risk and that AS3MT genetic variation may play an important role modulating such risk in northern Mexico, especially among children. genetics Arsenic Subjects with gene influence:AS3MT | Children | Study subjects Mexico blood | urine | water, drinking Arsenic | AS3MT Details Arsenic Poisoning | cellular response to DNA damage stimulus
7. Zhang A, et al. (2007). The results showed that long-term Arsenic exposure may be associated with damage of chromosomes and DNA, gene mutations, gene deletions, and alterations of DNA synthesis and repair ability. Arsenic Subjects with disease:Carcinoma | Subjects with disease:Ichthyosis | Subjects with disease:Precancerous Conditions | Study subjects China hair | urine Arsenic Details Arsenic Poisoning | DNA biosynthetic process | DNA repair | gene expression
8. Wasserman GA, et al. (2007). Exposure to arsenic from drinking water was associated with reduced intellectual function before and after adjusting for water manganese for blood lead levels, and for sociodemographic features. diet Arsenic | Lead | Manganese Children Bangladesh blood | urine | water, drinking Arsenic | Lead | Manganese Details Arsenic Poisoning | Learning Disorders
9. Creswell PD, et al. (2015). Exposure to elevated carbon monoxide levels at an indoor ice arena-Wisconsin, 2014 Carbon Monoxide Study subjects United States air Carbon Monoxide Details Carbon Monoxide Poisoning | Dizziness | Dyspnea | Headache | Nausea | Vomiting
10. Paterson JM, et al. (2012). Among older outpatients with no evidence of liver disease, moxifloxacin and levofloxacin were associated with an increased risk of acute liver injury relative to clarithromycin. cefuroxime axetil | Ciprofloxacin | Clarithromycin | Levofloxacin | Moxifloxacin Study subjects Canada Details Chemical and Drug Induced Liver Injury
11. Azziz-Baumgartner E, et al. (2012). Annual incidence of possible ciguatera fish poisoning was 4 per 1,000 person-years, and that of probable ciguatera fish poisoning was 7.5 per 1,000 person-years. Ciguatoxins Study subjects Puerto Rico Details Ciguatera Poisoning
12. No authors listed. (2005). This report describes 28 additional cases of hydrogen cyanamide-related illness that occurred during 2002-2004 in Italy; these illnesses suggest that the preventive measures adopted in 2003 to protect agricultural workers are inadequate. Cyanamide | Pesticides Workers Italy Details Agricultural Workers' Diseases | Cardiovascular Diseases | Eye Diseases | Neurologic Manifestations | Poisoning | Signs and Symptoms, Digestive | Signs and Symptoms, Respiratory | Skin Diseases | Skin Manifestations
13. No authors listed. (2001). During Jan-Feb 2001, eight cases of acute illness in the county of Ragusa (Italy) were attributed to exposure to Dormex, a plant growth regulator with hydrogen cyanamide as the active ingredient. Cyanamide | Pesticides Workers Italy Details Agricultural Workers' Diseases | Cardiovascular Diseases | Eye Diseases | Neurologic Manifestations | Poisoning | Signs and Symptoms, Digestive | Skin Diseases | Skin Manifestations
14. Wu Z, et al. (2017). We report urinary biomarkers for occupational exposure to N,N-dimethylformamide and reveal dose-response relationships between their levels and liver injury, with males having a greater risk of injury. sex Dimethylformamide Workers China urine methylformamide | N-acetyl-S-(N-methylcarbamoyl)cysteine Details Chemical and Drug Induced Liver Injury
15. Hutson JR, et al. (2012). Our results demonstrate that chronic and heavy alcohol use in pregnancy impairs folate transport to the fetus. Altered folate concentrations within the placenta and in the fetus may in part contribute to the deficits observed in the fetal alcohol spectrum disorders. alcohol drinking Ethanol Fetuses | Pregnant females Canada plasma | plasma, cord Folic Acid Details Fetal Alcohol Spectrum Disorders | transport
16. Wang Y, et al. (2012). We report a method for the determination of glyphosate in heart blood of a corpse by ion chromatography; this method is simple, sensitive, accurate, and can rapidly provided reliable clues and evidences for glyphosate poisoning cases. glyphosate Study subjects China blood glyphosate Details Death | Poisoning
17. Cecil KM, et al. (2011). Cincinnati Lead Study Gray-matter N-acetyl aspartate reductions associated with increasing childhood blood lead levels suggest that sustained childhood lead exposure produces an irreversible pattern of neuronal dysfunction, whereas associated white-matter choline declines indicate a permanent alteration to myelin architecture. Lead Study subjects United States Lead Details Lead Poisoning, Nervous System | metabolic process
18. Palaniappan K, et al. (2011). Among urban Indian children, higher blood lead levels are associated with decreased visual-motor abilities, particularly visual-motor integration. Lead Children India blood Lead Details Lead Poisoning, Nervous System, Childhood | behavior
19. Rajan P, et al. (2007). Normative Aging Study (NAS) We observed a deleterious association between current and cumulative lead burden and risk of psychiatric symptoms. At a given cumulative lead burden, participants with the ALAD 1-1 genotype appeared to be at greater risk than participants who were carriers of at least one variant ALAD allele. genetics Lead Subjects with gene influence:ALAD | Veterans United States blood | bone | patella | tibia Lead Details Lead Poisoning, Nervous System | Mental Disorders
20. Ferron MM, et al. (2012). The present study aimed to estimate the prevalence of environmental lead poisoning in children and to identify associated factors, as well as possible sources of lead contamination in the area. age | socioeconomic status Lead Children Brazil blood Lead Details Lead Poisoning
21. No authors listed. (2013). Adult Blood Lead Epidemiology and Surveillance (ABLES) Adverse health effects associated with very high blood lead levels underscore the need for increased efforts to prevent lead exposure at workplaces and in communities. Lead Study subjects | Workers United States blood Lead Details Lead Poisoning
22. Haefliger P, et al. (2009). Our investigations revealed a mass lead intoxication that occurred through inhalation and ingestion of soil and dust heavily contaminated with lead as a result of informal and unsafe used lead-acid batteries recycling. Lead Children | Subjects with disease:Lead Poisoning | Study subjects Senegal blood Lead Details Death | Lead Poisoning, Nervous System, Childhood
23. Caravanos J, et al. (2016). This study sought to characterize the number of years lost due to illness, disability, or early death from lead exposure in Argentina, Mexico, and Uruguay. Lead Study subjects Argentina|Mexico|
Uruguay
blood | soil Lead Details Lead Poisoning
24. No authors listed. (2009). Persons employed in high-risk lead-related occupations can transport lead dust home from a worksite through clothing, shoes, tools, or vehicles. Lead Children United States automobile | blood | child safety seat Lead Details Lead Poisoning
25. Dooyema CA, et al. (2012). The high levels of environmental contamination, percentage of children < 5 years of age with elevated blood lead levels (97%, > 45 micrograms per deciliter), and incidence of convulsions among children before death (82%) suggest that most of the recent childhood deaths in the two surveyed villages were caused by acute lead poisoning from gold ore-processing activities. Lead | Manganese | Mercury Children Nigeria blood Lead | Manganese | Mercury Details Lead Poisoning
26. Peplow D, et al. (2012). Results showed the Wayana were at a high lifetime risk of adverse effects from dietary exposure to mercury diet Mercury Study subjects Suriname hair Mercury Details Mercury Poisoning
27. Koirala S, et al. (2015). Acute mercury poisoning after home gold and silver smelting Mercury Study subjects United States blood Mercury Details Mercury Poisoning | Respiratory Distress Syndrome, Adult
28. Langley R, et al. (2014). Notes from the Field: Elemental Mercury Spill in School Bus and Residence - North Carolina, 2013 Mercury Children | Study subjects | Workers United States blood Mercury Details Mercury Poisoning
29. Kulkarni PA, et al. (2015). Severe illness from methyl bromide exposure at a condominium resort - U.S. Virgin Islands, March 2015 methyl bromide Study subjects Virgin Islands, U.S. serum methyl bromide Details Neurologic Manifestations | Neurotoxicity Syndromes
30. Yokoo EM, et al. (2003). This study suggests that adults exposed to methylmercury may be at risk for deficits in neurocognitive function. Methylmercury Compounds Study subjects Brazil hair Methylmercury Compounds Details Cognition Disorders | Mercury Poisoning, Nervous System | cognition
31. Z'gambo J, et al. (2016). This study sought to characterize acute poisoning with regard to demographic factors (i.e. age, sex and residence), common toxic agents used and their case fatality rates as well as the overall mortality rate of acute poisoning. Narcotics | Pesticides Children | Study subjects Zambia Details Poisoning
32. Kleinjan M, et al. (2012). International Study of Asthma and Allergies in Childhood (ISAAC) Nicotine dependence profiles are predicted by interactions between personal and environmental factors. age Nicotine Children Netherlands Nicotine Details Tobacco Use Disorder
33. Gallo V, et al. (2012). C8 Health Project (C8HP) These results show a positive association between Perfluorooctanoate and Perfluorooctane Sulfonate concentrations and serum alanine aminotransferase level, a marker of hepatocellular damage. perfluorooctane sulfonic acid | perfluorooctanoic acid Study subjects United States serum perfluorooctane sulfonic acid | perfluorooctanoic acid Details Chemical and Drug Induced Liver Injury
34. Darrow LA, et al. (2016). C8 Health Project (C8HP) Using exposure estimates that are not affected by reverse causation, our results complement evidence from previous cross-sectional studies showing a modest positive relationship between perfluorooctanoic acid and alanine aminotransferase levels, a marker of hepatocellular injury. perfluorooctanoic acid Study subjects | Workers United States GPT | perfluorooctanoic acid Details Chemical and Drug Induced Liver Injury | Liver Diseases | regulation of gene expression
35. Alves JS, et al. (2016). We observed changes in micronucleus genetic damage (influenced by PON1 polymorphism), superoxide dismutase activity, and levels of inorganic compounds in blood samples of agricultural workers exposed to complex mixtures of pesticides. genetics Pesticides Subjects with gene influence:PON1 | Study subjects | Workers Brazil blood Aluminum | Bromides | Chlorine | Iron | Magnesium | Phosphorus | Sulfur | Zinc Details Agricultural Workers' Diseases | Micronuclei, Chromosome-Defective | Organophosphate Poisoning | positive regulation of superoxide dismutase activity
36. Elefsiniotis IS, et al. (2007). Quizalofop-p-ethyl can induce a mixed cholestatic/hepatocellular liver injury. quizalofop-ethyl Workers Greece Details Chemical and Drug Induced Liver Injury | Cholestasis
37. Aschengrau A, et al. (2011). The results of this study suggest that risky behaviors, particularly drug use, are more frequent among adults with high tetrachloroethylene exposure levels during gestation and early childhood. Tetrachloroethylene Study subjects United States Tetrachloroethylene Details Substance-Related Disorders
38. Winnik L, et al. (2004). The aim of this study was the presentation of the chronic tetraethyl lead poisoning of a four-person family. Tetraethyl Lead Children | Subjects with disease:Hallucinations | Study subjects Poland serum Lead Details Lead Poisoning, Nervous System, Adult
39. No authors listed. (2003). This report describes the first known case in the United States of exposure to a Chinese rodenticide containing the toxin tetramethylenedisulfotetramine (TETS), a convulsant poison. tetramethylenedisulfotetramine Infants or newborns United States Details Neurotoxicity Syndromes
1–39 of 39 results.