These are exposure studies associated with the gene.
|Reference||Associated Study Title||Author's Summary||Study Factors||Stressor||Receptors||Country||Medium||Exposure Marker||Measurements||Outcome|
|1.||Clair HB, et al. (2018).||Anniston Community Health Survey (ACHS)||Toxicant-associated steatohepatitis was associated with increased exposures to specific PCB congeners, and the sum of PCBs had associations with insulin, leptin, adipocytokines, and hepatocyte apoptosis.||2,2',3,5,5',6-
||Subjects with disease:Fatty Liver | Subjects with disease:Liver Diseases | Study subjects||United States||serum||2,2',3,4',5',6-
||Details||Fatty Liver | positive regulation of cell death | regulation of apoptotic process|
|2.||He K, et al. (2013).||Coronary Artery Risk Development in Young Adults (CARDIA) Study||Our results provide longitudinal human data suggesting that people with high mercury exposure in young adulthood may have elevated risk of diabetes later in life.||Mercury||Study subjects||United States||nail, toe | plasma||Blood Glucose | INS | Mercury||Details||Diabetes Mellitus | regulation of insulin secretion involved in cellular response to glucose stimulus|
|3.||Jørgensen A, et al. (2015).||These findings support an adverse cardio-metabolic risk profile (leptin, insulin, and glucagon) associated with prenatal pesticide exposure in children with the 192R allele in PON1 paraoxonase gene.||genetics||Pesticides||Children | Fetuses | Subjects with gene influence:PON1||Denmark||serum||GCG | INS | LEP | SERPINE1||Details||Prenatal Exposure Delayed Effects|