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GeneGene: HFE

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The following diseases are associated with the HFE gene. This gene has either a direct association to a disease (M marker/mechanism and/or T therapeutic) or an inferred association via a curated chemical interaction.

Showing 1–165 of 165
  Disease Direct Evidence Inference Network References
1. Alzheimer Disease M Via 1 chemical: Iron View references.
2. Anemia, Iron-Deficiency M Via 1 chemical: Iron View references.
3. Hemochromatosis M Via 1 chemical: Iron View references.
4. Myelodysplastic Syndromes M Via 1 chemical: Valproic Acid View references.
5. Parkinson Disease M Via 1 chemical: Iron View references.
6. Porphyria Cutanea Tarda M Via 1 chemical: Iron View references.
7. MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 7 M   View references.
8. Porphyria, Variegate M   View references.
9. Autistic Disorder   Via 4 chemicals: Acetaminophen; Glutathione; Iron; Valproic Acid View references.
10. Fatty Liver   Via 4 chemicals: Stavudine; Ethinyl Estradiol; Iron; Valproic Acid View references.
11. Drug Toxicity   Via 3 chemicals: Stavudine; Didanosine; Doxorubicin View references.
12. Drug-Induced Liver Injury   Via 3 chemicals: Acetaminophen; Doxorubicin; Valproic Acid View references.
13. Adenocarcinoma   Via 2 chemicals: Doxorubicin; Ethinyl Estradiol View references.
14. Breast Neoplasms   Via 2 chemicals: Doxorubicin; Estradiol View references.
15. Carcinoma, Hepatocellular   Via 2 chemicals: Doxorubicin; Estradiol View references.
16. Carcinoma, Squamous Cell   Via 2 chemicals: Doxorubicin; Glutathione View references.
17. Cardiomyopathies   Via 2 chemicals: Doxorubicin; Iron View references.
18. Cardiomyopathy, Dilated   Via 2 chemicals: Doxorubicin; Iron View references.
19. Craniofacial Abnormalities   Via 2 chemicals: triadimefon; Valproic Acid View references.
20. Endometrial Neoplasms   Via 2 chemicals: Doxorubicin; Estradiol View references.
21. Hepatomegaly   Via 2 chemicals: Iron; triadimefon View references.
22. HIV Infections   Via 2 chemicals: Stavudine; Iron View references.
23. Kidney Diseases   Via 2 chemicals: Doxorubicin; Estradiol View references.
24. Liver Cirrhosis, Experimental   Via 2 chemicals: Doxorubicin; Estradiol View references.
25. Liver Diseases   Via 2 chemicals: Acetaminophen; triadimefon View references.
26. Liver Neoplasms   Via 2 chemicals: Iron; triadimefon View references.
27. Liver Neoplasms, Experimental   Via 2 chemicals: Doxorubicin; triadimefon View references.
28. Lung Neoplasms   Via 2 chemicals: Doxorubicin; Iron View references.
29. Mammary Neoplasms, Experimental   Via 2 chemicals: Doxorubicin; Estradiol View references.
30. Myocardial Reperfusion Injury   Via 2 chemicals: Estradiol; Iron View references.
31. Nephrotic Syndrome   Via 2 chemicals: Doxorubicin; Iron View references.
32. Neurodegenerative Diseases   Via 2 chemicals: Acetaminophen; Iron View references.
33. Prostatic Neoplasms   Via 2 chemicals: Doxorubicin; Estradiol View references.
34. Skin Neoplasms   Via 2 chemicals: Doxorubicin; Iron View references.
35. Thyroid Neoplasms   Via 2 chemicals: Doxorubicin; triadimefon View references.
36. Abnormalities, Drug-Induced   Via 1 chemical: Valproic Acid View references.
37. Abnormalities, Multiple   Via 1 chemical: Valproic Acid View references.
38. Acne Vulgaris   Via 1 chemical: Ethinyl Estradiol View references.
39. alpha 1-Antitrypsin Deficiency   Via 1 chemical: Iron View references.
40. Amblyopia   Via 1 chemical: Valproic Acid View references.
41. Anemia   Via 1 chemical: Iron View references.
42. Anemia, Sideroblastic   Via 1 chemical: Iron View references.
43. Angioedema   Via 1 chemical: Acetaminophen View references.
44. Anxiety Disorders   Via 1 chemical: Valproic Acid View references.
45. Arrhythmias, Cardiac   Via 1 chemical: Iron View references.
46. Arteriosclerosis   Via 1 chemical: Ethinyl Estradiol View references.
47. Arthritis, Experimental   Via 1 chemical: Ethinyl Estradiol View references.
48. Ataxia Telangiectasia   Via 1 chemical: Iron View references.
49. Atherosclerosis   Via 1 chemical: Iron View references.
50. Melanoma, Experimental   Via 1 chemical: Acetaminophen View references.
51. Bacterial Infections   Via 1 chemical: Iron View references.
52. Bipolar Disorder   Via 1 chemical: Valproic Acid View references.
53. Bone Diseases, Developmental   Via 1 chemical: Valproic Acid View references.
54. Bone Marrow Neoplasms   Via 1 chemical: Doxorubicin View references.
55. Brain Neoplasms   Via 1 chemical: Doxorubicin View references.
56. Candidiasis, Vulvovaginal   Via 1 chemical: Estradiol View references.
57. Carcinoid Tumor   Via 1 chemical: Doxorubicin View references.
58. Carcinoma, Renal Cell   Via 1 chemical: Doxorubicin View references.
59. Cataract   Via 1 chemical: Acetaminophen View references.
60. Cell Transformation, Neoplastic   Via 1 chemical: Estradiol View references.
61. Cholestasis   Via 1 chemical: Ethinyl Estradiol View references.
62. Cleft Palate   Via 1 chemical: triadimefon View references.
63. Colonic Neoplasms   Via 1 chemical: Iron View references.
64. Colorectal Neoplasms   Via 1 chemical: Doxorubicin View references.
65. Cystic Fibrosis   Via 1 chemical: Glutathione View references.
66. Diabetes Mellitus   Via 1 chemical: Iron View references.
67. Diabetes Mellitus, Type 1   Via 1 chemical: Iron View references.
68. Diabetes Mellitus, Type 2   Via 1 chemical: Iron View references.
69. Drug-Induced Liver Injury, Chronic   Via 1 chemical: Acetaminophen View references.
70. Dystonia   Via 1 chemical: Valproic Acid View references.
71. Encephalomyelitis, Autoimmune, Experimental   Via 1 chemical: Ethinyl Estradiol View references.
72. Endomyocardial Fibrosis   Via 1 chemical: Doxorubicin View references.
73. Epilepsies, Myoclonic   Via 1 chemical: Valproic Acid View references.
74. Epilepsies, Partial   Via 1 chemical: Valproic Acid View references.
75. Epilepsy, Absence   Via 1 chemical: Valproic Acid View references.
76. Epilepsy, Complex Partial   Via 1 chemical: Valproic Acid View references.
77. Epilepsy, Tonic-Clonic   Via 1 chemical: Valproic Acid View references.
78. Fetal Diseases   Via 1 chemical: Valproic Acid View references.
79. Fetal Growth Retardation   Via 1 chemical: Valproic Acid View references.
80. Fibromatosis, Aggressive   Via 1 chemical: Doxorubicin View references.
81. Friedreich Ataxia   Via 1 chemical: Iron View references.
82. Glioblastoma   Via 1 chemical: Doxorubicin View references.
83. Head and Neck Neoplasms   Via 1 chemical: Doxorubicin View references.
84. Heart Diseases   Via 1 chemical: Doxorubicin View references.
85. Hemangiosarcoma   Via 1 chemical: Doxorubicin View references.
86. Hemosiderosis   Via 1 chemical: Iron View references.
87. Hepatitis, Viral, Human   Via 1 chemical: Iron View references.
88. Hepatolenticular Degeneration   Via 1 chemical: Iron View references.
89. Herpes Genitalis   Via 1 chemical: Estradiol View references.
90. Hodgkin Disease   Via 1 chemical: Doxorubicin View references.
91. Hot Flashes   Via 1 chemical: Estradiol View references.
92. Hyperalgesia   Via 1 chemical: Acetaminophen View references.
93. Hypertension, Pregnancy-Induced   Via 1 chemical: Hydralazine View references.
94. Hypogonadism   Via 1 chemical: Iron View references.
95. Hypospadias   Via 1 chemical: Ethinyl Estradiol View references.
96. Hypothyroidism   Via 1 chemical: Iron View references.
97. Infertility, Female   Via 1 chemical: Ethinyl Estradiol View references.
98. Infertility, Male   Via 1 chemical: Ethinyl Estradiol View references.
99. Insulin Resistance   Via 1 chemical: Estradiol View references.
100. Iron Metabolism Disorders   Via 1 chemical: Iron View references.
101. Jaw Abnormalities   Via 1 chemical: triadimefon View references.
102. Kidney Failure   Via 1 chemical: Doxorubicin View references.
103. Kidney Failure, Chronic   Via 1 chemical: Doxorubicin View references.
104. Kidney Neoplasms   Via 1 chemical: Estradiol View references.
105. Leukemia, Erythroblastic, Acute   Via 1 chemical: Doxorubicin View references.
106. Leukemia, Myeloid, Acute   Via 1 chemical: Valproic Acid View references.
107. Lewy Body Disease   Via 1 chemical: Iron View references.
108. Liver Cirrhosis   Via 1 chemical: Iron View references.
109. Liver Diseases, Alcoholic   Via 1 chemical: Iron View references.
110. Liver Failure   Via 1 chemical: Stavudine View references.
111. Liver Failure, Acute   Via 1 chemical: Acetaminophen View references.
112. Lung Diseases, Interstitial   Via 1 chemical: Valproic Acid View references.
113. Lymphoma   Via 1 chemical: Doxorubicin View references.
114. Lymphoma, T-Cell   Via 1 chemical: Doxorubicin View references.
115. Macular Degeneration   Via 1 chemical: Iron View references.
116. Melanoma   Via 1 chemical: Doxorubicin View references.
117. Migraine Disorders   Via 1 chemical: Valproic Acid View references.
118. Mucositis   Via 1 chemical: Doxorubicin View references.
119. Multiple Sclerosis, Chronic Progressive   Via 1 chemical: Iron View references.
120. Musculoskeletal Abnormalities   Via 1 chemical: Valproic Acid View references.
121. Mycoses   Via 1 chemical: Iron View references.
122. Myocardial Ischemia   Via 1 chemical: Iron View references.
123. Neoplasm Metastasis   Via 1 chemical: Doxorubicin View references.
124. Neovascularization, Pathologic   Via 1 chemical: Estradiol View references.
125. Nephrosis   Via 1 chemical: Doxorubicin View references.
126. Neural Tube Defects   Via 1 chemical: Valproic Acid View references.
127. Neuroblastoma   Via 1 chemical: Doxorubicin View references.
128. Status Epilepticus   Via 1 chemical: Valproic Acid View references.
129. Lymphoma, Non-Hodgkin   Via 1 chemical: Doxorubicin View references.
130. Osteoarthritis   Via 1 chemical: Iron View references.
131. Osteoporosis   Via 1 chemical: Iron View references.
132. Osteosarcoma   Via 1 chemical: Doxorubicin View references.
133. Pain   Via 1 chemical: Acetaminophen View references.
134. Panic Disorder   Via 1 chemical: Ethinyl Estradiol View references.
135. Papilloma   Via 1 chemical: Iron View references.
136. Parasomnias   Via 1 chemical: Iron View references.
137. Phyllodes Tumor   Via 1 chemical: Doxorubicin View references.
138. Pituitary Diseases   Via 1 chemical: Iron View references.
139. Poisoning   Via 1 chemical: Iron View references.
140. Hydrocephalus   Via 1 chemical: Valproic Acid View references.
141. Pre-Eclampsia   Via 1 chemical: Iron View references.
142. Protozoan Infections   Via 1 chemical: Iron View references.
143. Pruritus   Via 1 chemical: Ethinyl Estradiol View references.
144. Pseudolymphoma   Via 1 chemical: Valproic Acid View references.
145. Restless Legs Syndrome   Via 1 chemical: Iron View references.
146. Rhabdomyosarcoma   Via 1 chemical: Valproic Acid View references.
147. Sarcoma   Via 1 chemical: Doxorubicin View references.
148. Sarcoma, Ewing's   Via 1 chemical: Doxorubicin View references.
149. Sarcoma, Kaposi   Via 1 chemical: Doxorubicin View references.
150. Seizures   Via 1 chemical: Valproic Acid View references.
151. Soft Tissue Neoplasms   Via 1 chemical: Doxorubicin View references.
152. Spermatocele   Via 1 chemical: Ethinyl Estradiol View references.
153. Spinal Dysraphism   Via 1 chemical: Valproic Acid View references.
154. Sudden Infant Death   Via 1 chemical: Iron View references.
155. Thrombophilia   Via 1 chemical: Ethinyl Estradiol View references.
156. Thrombosis   Via 1 chemical: Ethinyl Estradiol View references.
157. Translocation, Genetic   Via 1 chemical: Valproic Acid View references.
158. Tuberculosis   Via 1 chemical: Iron View references.
159. Unverricht-Lundborg Syndrome   Via 1 chemical: Valproic Acid View references.
160. Urinary Bladder Neoplasms   Via 1 chemical: Doxorubicin View references.
161. Urogenital Abnormalities   Via 1 chemical: Valproic Acid View references.
162. Urticaria   Via 1 chemical: Acetaminophen View references.
163. Uterine Neoplasms   Via 1 chemical: Ethinyl Estradiol View references.
164. Venous Thrombosis   Via 1 chemical: Ethinyl Estradiol View references.
165. Ventricular Dysfunction, Left   Via 1 chemical: Doxorubicin View references.
Showing 1–165 of 165
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