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ChemicalChemical: Acids, Heterocyclic

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The following diseases are associated with Acids, Heterocyclic or at least one of its descendants. Each association is direct (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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  Chemical Disease Direct Evidence Inference Network Inference Score References
1. clometacin Liver Diseases M   1
2. Hydroxyindoleacetic Acid Impulse Control Disorders M   1
3. Hydroxyindoleacetic Acid Antisocial Personality Disorder M   1
4. Hydroxyindoleacetic Acid Firesetting Behavior M   1
5. 6-Aminonicotinamide Cleft Palate M   2
6. Isoniazid Seizures M   1
7. Arecoline Oral Submucous Fibrosis M Via 3 genes: MMP2; PTGS2; TIMP1 33.83 1
8. Isoniazid Drug-Induced Liver Injury M Via 3 genes: CYP2E1; GSTT1; NAT2 24.52 7
9. Niacinamide Diabetes Mellitus, Type 2 M Via 3 genes: IL6; INS1; PPARG 23.78 3
10. pipecolic acid Peroxisomal Disorders M Via 1 gene: PIPOX 14.47 1
11. Isoniazid Mycobacterium Infections T   1
12. Isoniazid Tuberculosis T   6
13. Kynurenic Acid Seizures T   1
14. argatroban Thrombosis T   2
15. argatroban Embolism and Thrombosis T   1
16. Niacinamide Pemphigoid, Bullous T   1
17. Nicorandil Reperfusion Injury T   1
18. tazarotene Psoriasis T   2
19. Ethionamide Tuberculosis T   2
20. tiagabine Seizures T   1
21. argatroban Thrombocytopenia T   1
22. LG 100268 Mammary Neoplasms, Experimental T   1
23. motesanib diphosphate Thyroid Neoplasms T   1
24. Etodolac Colorectal Neoplasms T Via 4 genes: APC; BCL2; BIRC5; PTGS2 30.58 8
25. Etodolac Colonic Neoplasms T Via 3 genes: APC; BCL2; BIRC5 23.56 5
26. LG 100268 Breast Neoplasms T Via 3 genes: CCND1; CYP19A1; RB1 19.94 4
27. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone HIV Infections T Via 2 genes: CDKN1A; GADD45A 16.91 2
28. Etodolac ALLERGIC RHINITIS T Via 1 gene: PTGS2 8.64 1
29. Niacinamide Prostatic Neoplasms   Via 7 genes: BAX; CASP9; CDKN1A; IL6; INS; PARP1; TP53 44.99 11
30. LG 100268 Prostatic Neoplasms   Via 5 genes: CCND1; CYP19A1; HSD17B1; IGFBP6; RXRA 37.00 6
31. Niacinamide Osteoporosis   Via 4 genes: COL1A1; IL6; TNFRSF11B; TNFSF11 36.71 4
32. Arecoline Liver Cirrhosis, Experimental   Via 4 genes: MMP2; MT1A; PTGS2; TIMP1 36.62 6
33. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Urinary Bladder Neoplasms   Via 4 genes: CDKN1A; RB1; TFRC; TP53 34.82 5
34. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Prostatic Neoplasms   Via 5 genes: CCND1; CCND2; CDKN1A; GADD45A; TP53 34.51 7
35. Isoniazid Prostatic Neoplasms   Via 5 genes: CYP2E1; CYP3A4; GSTT1; NAT2; SOD2 33.91 11
36. Etodolac Prostatic Neoplasms   Via 5 genes: APC; BCL2; CASP9; PTGS2; RXRA 33.33 7
37. Etodolac Stomach Neoplasms   Via 4 genes: APC; BIRC2; BIRC5; PTGS2 30.77 4
38. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Lung Neoplasms   Via 4 genes: CCND1; CDKN1A; TFRC; TP53 30.28 8
39. Etodolac Autistic Disorder   Via 4 genes: APC; BCL2; ITGA4; PTGS2 29.87 5
40. Etodolac Cardiomyopathies   Via 3 genes: HGF; ITGB1; PTGS2 28.82 4
41. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Breast Neoplasms   Via 4 genes: CCND1; RB1; TFRC; TP53 28.68 8
42. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Alzheimer Disease   Via 3 genes: BAX; BCL2; CASP3 27.45 1
43. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Leukemia, Lymphocytic, Chronic, B-Cell   Via 3 genes: CCND1; TFRC; TP53 26.89 3
44. Etodolac Breast Neoplasms   Via 4 genes: BCL2; BIRC5; CASP7; PTGS2 26.79 7
45. Niacin Diabetes Mellitus, Type 2   Via 3 genes: EDNRB; HMOX1; LEPR 25.89 3
46. Niflumic Acid Breast Neoplasms   Via 3 genes: CYP19A1; HSPA1B; PTGS2 25.17 5
47. Niacinamide Leukemia, Lymphocytic, Chronic, B-Cell   Via 3 genes: IL6; TNFSF11; TP53 24.85 3
48. tazarotene Alzheimer Disease   Via 3 genes: BAX; BCL2; CASP3 24.82 1
49. Niacinamide HIV Infections   Via 3 genes: BAX; CDKN1A; MDM2 24.40 1
50. Niacinamide Breast Neoplasms   Via 4 genes: FOS; IL6; JUN; TP53 24.23 7
51. tazarotene Breast Neoplasms   Via 3 genes: BCL2; RARB; SLC5A5 24.19 4
52. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Esophageal Neoplasms   Via 3 genes: CCND1; CDKN1A; TP53 23.85 3
53. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Colorectal Neoplasms   Via 3 genes: CCND1; TFRC; TP53 23.32 8
54. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Erectile Dysfunction   Via 2 genes: BCL2; BCL2L1 22.49 1
55. Niacinamide Hypercalcemia   Via 2 genes: TNFRSF11B; TNFSF11 22.26 1
56. Niacinamide Esophageal Neoplasms   Via 3 genes: BAX; CDKN1A; TP53 21.90 2
57. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Intestinal Neoplasms   Via 2 genes: BAX; BCL2 21.82 2
58. tazarotene Prostatic Neoplasms   Via 3 genes: BAX; BCL2; SLC5A5 21.67 4
59. Niacinamide Alzheimer Disease   Via 3 genes: BAX; CASP3; PPARG 21.47 2
60. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Carcinoma   Via 2 genes: BCL2; BCL2L1 21.47 1
61. Etodolac Leukemia, Promyelocytic, Acute   Via 2 genes: CD44; ITGAL 20.77 3
62. Etodolac Liver Cirrhosis, Experimental   Via 3 genes: CYP1A2; HGF; PTGS2 20.38 9
63. tazarotene Intestinal Neoplasms   Via 2 genes: BAX; BCL2 20.28 2
64. Niacinamide Stomach Neoplasms   Via 3 genes: CDKN1A; JUN; MAPK8 20.12 3
65. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Adenoma   Via 2 genes: BCL2; BCL2L1 20.00 2
66. Niacinamide Carcinoma, Hepatocellular   Via 3 genes: FOS; IL6; TP53 19.85 5
67. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Liver Neoplasms, Experimental   Via 2 genes: BCL2; BCL2L1 19.56 1
68. Niflumic Acid Skin Diseases   Via 2 genes: HSPA1B; PTGS2 19.48 2
69. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Osteosarcoma   Via 2 genes: RB1; TP53 19.47 3
70. Etodolac Adenomatous Polyposis Coli   Via 2 genes: APC; PTGS2 19.46 7
71. Niacinamide Lung Neoplasms   Via 3 genes: CDKN1A; FOS; TP53 19.05 6
72. Arecoline Urinary Bladder Neoplasms   Via 2 genes: MT1A; PTGS2 19.01 4
73. Arecoline Carcinoma, Squamous Cell   Via 2 genes: MT1A; PTGS2 18.66 3
74. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Leukemia   Via 2 genes: BIRC2; CCND1 18.49 2
75. Niacinamide Osteosarcoma   Via 2 genes: JUN; TP53 18.07 4
76. Arecoline Arthritis, Rheumatoid   Via 2 genes: MMP2; PTGS2 18.02 2
77. Niacinamide Intestinal Neoplasms   Via 2 genes: BAX; CDKN1A 17.82 3
78. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Esophageal Neoplasms   Via 2 genes: CCND1; XIAP 17.74 2
79. Arecoline Carcinoma, Hepatocellular   Via 2 genes: MT1A; PTGS2 17.61 2
80. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Ovarian Neoplasms   Via 2 genes: CCND2; GADD45A 17.58 2
81. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Glioma   Via 2 genes: TFRC; TP53 17.51 2
82. Arecoline Drug-Induced Liver Injury   Via 2 genes: MMP2; PTGS2 17.45 2
83. Etodolac Carcinoma   Via 2 genes: BCL2; PTGS2 17.01 2
84. Niacinamide Obesity   Via 2 genes: ADIPOQ; PPARG 16.57 2
85. Etodolac Skin Diseases   Via 2 genes: CD44; PTGS2 16.34 2
86. Niacin Liver Diseases   Via 2 genes: ENO3; HMOX1 16.26 4
87. Etodolac Carcinoma, Renal Cell   Via 2 genes: BIRC5; PTGS2 16.25 2
88. Etodolac Pancreatic Neoplasms   Via 2 genes: CD44; PTGS2 16.25 4
89. Etodolac Leukemia   Via 2 genes: BCL2; BIRC2 16.23 2
90. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Pancreatic Neoplasms   Via 2 genes: GADD45A; TP53 16.20 3
91. nicotinamide N-oxide Mastitis   Via 1 gene: IL8RB 16.10 1
92. Etodolac Adenocarcinoma   Via 2 genes: APC; PTGS2 16.08 4
93. Isoniazid Liver Cirrhosis, Experimental   Via 2 genes: GSTA2; TRF 16.02 2
94. Etodolac Urinary Bladder Neoplasms   Via 2 genes: PTGS2; UGT2B7 15.86 4
95. Niacinamide Glioma   Via 2 genes: PPARG; TP53 15.42 2
96. Etodolac Liver Neoplasms, Experimental   Via 2 genes: BCL2; CYP1A2 15.25 2
97. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Lung Neoplasms   Via 2 genes: BCL2L1; CCND1 15.22 3
98. delta-1-piperidine-6-carboxylic acid Peroxisomal Disorders   Via 1 gene: PIPOX 15.16 1
99. Niacinamide Psoriasis   Via 2 genes: IL6; TP53 15.12 2
100. Niacinamide Liver Cirrhosis, Experimental   Via 2 genes: ADIPOQ; IGFBP1 15.10 2
101. Isoniazid Lung Neoplasms   Via 2 genes: A2M; CYP2E1 15.09 4
102. Meperidine Deficiency Diseases   Via 1 gene: CES1 14.93 1
103. AGN 190299 Ichthyosis, X-Linked   Via 1 gene: STS 14.88 1
104. Niacinamide Colonic Neoplasms   Via 2 genes: FOXO1; TP53 14.80 3
105. argatroban Hypoprothrombinemias   Via 1 gene: F2 14.66 1
106. isonicotinamide PAGET DISEASE, JUVENILE   Via 1 gene: TNFRSF11B 14.57 1
107. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Carcinoma, Hepatocellular   Via 2 genes: RB1; TP53 14.39 5
108. Niacin Liver Cirrhosis, Experimental   Via 2 genes: HMOX1; PCK1 14.37 3
109. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Colonic Neoplasms   Via 2 genes: CCND1; TP53 14.32 3
110. LG 100268 Colorectal Neoplasms   Via 2 genes: CCND1; PPARG 14.28 2
111. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Stomach Neoplasms   Via 2 genes: CDKN1A; GADD45A 14.27 2
112. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Prostatic Neoplasms   Via 2 genes: BAX; BCL2 14.26 2
113. Niflumic Acid Prostatic Neoplasms   Via 2 genes: CYP19A1; PTGS2 14.24 5
114. Niacin VITAMIN E, FAMILIAL ISOLATED DEFICIENCY OF   Via 1 gene: TTPA 14.19 1
115. flunixin Sleep Deprivation   Via 1 gene: PTGS1 14.18 1
116. Niacinamide Urinary Bladder Neoplasms   Via 2 genes: CDKN1A; TP53 14.15 3
117. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Breast Neoplasms   Via 2 genes: CCND1; NFKBIA 14.07 2
118. Streptonigrin Fanconi Anemia   Via 1 gene: FANCG 14.02 1
119. Niacinamide Melanoma   Via 2 genes: MDM2; TP53 14.00 1
120. morniflumate Colitis, Ulcerative   Via 1 gene: SLC26A3 13.99 1
121. tazarotene Ichthyosis, X-Linked   Via 1 gene: STS 13.89 1
122. Etodolac Carcinoma, Hepatocellular   Via 2 genes: BIRC5; PTGS2 13.83 2
123. Meperidine Opioid-Related Disorders   Via 1 gene: CES1 13.83 1
124. Meperidine Cocaine-Related Disorders   Via 1 gene: CES1 13.83 2
125. Kynurenic Acid Neurobehavioral Manifestations   Via 1 gene: CHRNA7 13.78 1
126. tazarotene THYROID DYSHORMONOGENESIS 1   Via 1 gene: SLC5A5 13.74 1
127. Niacin GLYCOGEN STORAGE DISEASE XIII   Via 1 gene: ENO3 13.64 1
128. Etodolac Alzheimer Disease   Via 2 genes: BCL2; CASP3 13.58 1
129. Isoniazid BRUCK SYNDROME 2   Via 1 gene: PLOD2 13.54 1
130. isonicotinamide CAROTID INTIMAL MEDIAL THICKNESS 1   Via 1 gene: PPARG 13.47 1
131. Kynurenic Acid EPILEPSY, IDIOPATHIC GENERALIZED   Via 1 gene: CHRNA7 13.44 1
132. Nicotinic Acids Intestinal Perforation   Via 1 gene: NOS3 13.44 1
133. AGN 190299 Sciatic Neuropathy   Via 1 gene: RARB 13.38 1
134. Arecoline Lymphatic Metastasis   Via 1 gene: MT1A 13.36 1
135. Niflumic Acid VAS DEFERENS, CONGENITAL BILATERAL APLASIA OF   Via 1 gene: CFTR 13.35 3
136. Arecoline TORG-WINCHESTER SYNDROME   Via 1 gene: MMP2 13.34 2
137. flunixin Intestinal Polyps   Via 1 gene: PTGS1 13.33 1
138. Niflumic Acid HYPERBILIRUBINEMIA, TRANSIENT FAMILIAL NEONATAL   Via 1 gene: UGT1A1 13.32 1
139. Niflumic Acid Crigler-Najjar Syndrome   Via 1 gene: UGT1A1 13.32 1
140. Niflumic Acid Gilbert Disease   Via 1 gene: UGT1A1 13.32 4
141. Niflumic Acid CRIGLER-NAJJAR SYNDROME, TYPE II   Via 1 gene: UGT1A1 13.32 1
142. Niflumic Acid AROMATASE EXCESS SYNDROME   Via 1 gene: CYP19A1 13.29 1
143. nicotinamide-beta-riboside Neurodegenerative Diseases   Via 1 gene: SIRT1 13.28 2
144. Niacin Obesity, Morbid   Via 1 gene: LEPR 13.26 1
145. Niacinamide Drug-Induced Liver Injury   Via 2 genes: BAX; IL6 13.25 2
146. Niacinamide Colorectal Neoplasms   Via 2 genes: PPARG; TP53 13.24 8
147. Niacin CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 3   Via 1 gene: TPM1 13.18 1
148. Isoniazid PSEUDOXANTHOMA ELASTICUM, FORME FRUSTE   Via 1 gene: ABCC6 13.14 1
149. Niacin Breast Neoplasms   Via 2 genes: EDNRB; HMOX1 13.12 2
150. AGN 190299 Musculoskeletal Abnormalities   Via 1 gene: RARG 13.07 1
151. Orotic Acid Sciatic Neuropathy   Via 1 gene: RXRA 13.06 1
152. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Arenaviridae Infections   Via 1 gene: TFRC 13.05 1
153. Isoniazid GOUT, HPRT-RELATED   Via 1 gene: HPRT1 13.04 1
154. Isoniazid Lesch-Nyhan Syndrome   Via 1 gene: HPRT1 13.04 1
155. Nicotinic Acids Coronary Vasospasm   Via 1 gene: NOS3 13.03 1
156. Niacinamide Cleidocranial Dysplasia   Via 1 gene: RUNX2 12.99 3
157. Niacinamide Stomatognathic System Abnormalities   Via 1 gene: RUNX2 12.99 1
158. Etodolac DESMOID DISEASE, HEREDITARY   Via 1 gene: APC 12.99 1
159. isonicotinamide Osteolysis   Via 1 gene: TNFRSF11B 12.96 1
160. flunixin Anemia, Aplastic   Via 1 gene: PTGS1 12.88 1
161. Etodolac WHIM SYNDROME   Via 1 gene: CXCR4 12.87 1
162. Niacinamide Glycogen Storage Disease Type I   Via 1 gene: G6PC 12.87 1
163. arecaidine esters Diabetes Mellitus, Experimental   Via 1 gene: CHRM2 12.80 1
164. Orotic Acid Hyperlipoproteinemias   Via 1 gene: PPARA 12.78 1
165. isonicotinamide LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 2   Via 1 gene: PPARG 12.78 1
166. isonicotinamide Lipodystrophy, Familial Partial   Via 1 gene: PPARG 12.78 1
167. Niacinamide alpha-Thalassemia   Via 1 gene: HBA1 12.75 1
168. Nicotinic Acids Hypertension, Portal   Via 1 gene: NOS3 12.74 1
169. Niacinamide MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 10   Via 1 gene: INS 12.66 1
170. Arecoline Maxillary Diseases   Via 1 gene: MMP2 12.65 1
171. Arecoline Mandibular Diseases   Via 1 gene: MMP2 12.65 1
172. Arecoline Osteonecrosis   Via 1 gene: MMP2 12.65 1
173. Arecoline Bone Diseases   Via 1 gene: MMP2 12.65 1
174. Niacinamide OSTEOPETROSIS, AUTOSOMAL RECESSIVE 2   Via 1 gene: TNFSF11 12.64 1
175. Niacinamide Osteopetrosis   Via 1 gene: TNFSF11 12.64 1
176. isonicotinamide Hypercalcemia   Via 1 gene: TNFRSF11B 12.63 1
177. Niacinamide PAGET DISEASE, JUVENILE   Via 1 gene: TNFRSF11B 12.62 1
178. Niflumic Acid Gynecomastia   Via 1 gene: CYP19A1 12.60 1
179. Etodolac DEAFNESS, AUTOSOMAL RECESSIVE 39   Via 1 gene: HGF 12.59 1
180. Etodolac Wounds, Penetrating   Via 1 gene: HGF 12.59 1
181. Niacin Muscular Diseases   Via 1 gene: ENO3 12.54 1
182. Nicotinic Acids Diabetic Angiopathies   Via 1 gene: NOS3 12.52 1
183. Niacin ABCD SYNDROME   Via 1 gene: EDNRB 12.51 1
184. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile ECTODERMAL DYSPLASIA, ANHIDROTIC, WITH T-CELL IMMUNODEFICIENCY, AUTOSOMAL DOMINANT   Via 1 gene: NFKBIA 12.48 1
185. Niacin NEURONOPATHY, DISTAL HEREDITARY MOTOR, TYPE IIB   Via 1 gene: HSPB1 12.41 1
186. Niacin CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2F   Via 1 gene: HSPB1 12.41 1
187. tazarotene Sciatic Neuropathy   Via 1 gene: RARB 12.40 1
188. LG 100268 CHOLESTASIS, BENIGN RECURRENT INTRAHEPATIC, 2   Via 1 gene: ABCB11 12.39 1
189. LG 100268 CHOLESTASIS, PROGRESSIVE FAMILIAL INTRAHEPATIC, 2   Via 1 gene: ABCB11 12.39 1
190. Niacinamide HEINZ BODY ANEMIAS   Via 1 gene: HBA1 12.35 1
191. Nicotinic Acids Hypertension, Pregnancy-Induced   Via 1 gene: NOS3 12.34 1
192. Nicotinic Acids STROKE, ISCHEMIC   Via 1 gene: NOS3 12.34 1
193. Niflumic Acid RENAL ADYSPLASIA   Via 1 gene: CFTR 12.25 1
194. Arecoline Bone Diseases, Metabolic   Via 1 gene: MMP2 12.24 1
195. Arecoline Nose Neoplasms   Via 1 gene: MMP2 12.24 1
196. Isoniazid Blood Protein Disorders   Via 1 gene: A2M 12.23 1
197. Isoniazid Lung Diseases, Obstructive   Via 1 gene: A2M 12.23 1
198. Niflumic Acid Critical Illness   Via 1 gene: CYP19A1 12.19 1
199. Etodolac Neuralgia   Via 1 gene: CXCR4 12.18 1
200. Meperidine Hypercholesterolemia   Via 1 gene: CES1 12.15 1
201. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Sarcoma, Synovial   Via 1 gene: BCL2 12.11 1
202. arecaidine Diabetes Mellitus, Experimental   Via 1 gene: CHRM2 12.10 1
203. Niflumic Acid Muscular Dystrophy, Facioscapulohumeral   Via 1 gene: HSPA1B 12.10 1
204. argatroban Brain Ischemia   Via 1 gene: F2 12.09 1
205. tazarotene Musculoskeletal Abnormalities   Via 1 gene: RARG 12.09 1
206. isonicotinamide Pituitary ACTH Hypersecretion   Via 1 gene: PPARG 12.08 1
207. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Lymphoproliferative Disorders   Via 1 gene: XIAP 12.06 1
208. Niacinamide Thalassemia   Via 1 gene: HBA1 12.06 1
209. Niacinamide Polycythemia Vera   Via 1 gene: HBA1 12.06 1
210. Isoniazid Pseudoxanthoma Elasticum   Via 1 gene: ABCC6 12.04 4
211. Niacinamide CHROMOSOME 22q13.3 DELETION SYNDROME   Via 1 gene: INS 11.97 1
212. Niacinamide MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 1   Via 1 gene: INS 11.97 1
213. Niflumic Acid PANCREATITIS, HEREDITARY   Via 1 gene: CFTR 11.96 1
214. Nicotinic Acids Hyperinsulinism   Via 1 gene: NOS3 11.93 1
215. isonicotinamide Bone Resorption   Via 1 gene: TNFRSF11B 11.93 2
216. arecaidine esters Diabetes Mellitus, Type 1   Via 1 gene: CHRM2 11.93 1
217. Etodolac Calcinosis   Via 1 gene: ITGB1 11.91 1
218. Etodolac Leukemia, Megakaryoblastic, Acute   Via 1 gene: BIRC5 11.91 1
219. Niflumic Acid Pseudohermaphroditism   Via 1 gene: CYP19A1 11.90 1
220. LG 100268 AROMATASE EXCESS SYNDROME   Via 1 gene: CYP19A1 11.90 1
221. Etodolac Fibromatosis, Abdominal   Via 1 gene: APC 11.89 1
222. Isoniazid MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 6   Via 1 gene: SOD2 11.88 1
223. Niacin Albuminuria   Via 1 gene: LEPR 11.87 1
224. Kynurenic Acid Epilepsy   Via 1 gene: CHRNA7 11.86 1
225. LG 100268 CAROTID INTIMAL MEDIAL THICKNESS 1   Via 1 gene: PPARG 11.86 1
226. LG 100268 Infertility, Female   Via 1 gene: NR5A2 11.83 1
227. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Lymphoma, T-Cell, Cutaneous   Via 1 gene: BAX 11.82 1
228. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Ectodermal Dysplasia   Via 1 gene: NFKBIA 11.79 1
229. AGN 190299 Uterine Cervical Neoplasms   Via 1 gene: RARB 11.77 1
230. Arecoline Carcinoma in Situ   Via 1 gene: PTGS2 11.77 2
231. Niflumic Acid Carcinoma in Situ   Via 1 gene: PTGS2 11.77 2
232. Arecoline Leiomyosarcoma   Via 1 gene: PTGS2 11.77 1
233. Niflumic Acid Leiomyosarcoma   Via 1 gene: PTGS2 11.77 1
234. arecaidine Oral Submucous Fibrosis   Via 1 gene: TIMP1 11.76 1
235. Niflumic Acid Pancreatitis, Chronic   Via 1 gene: CFTR 11.74 1
236. Niflumic Acid Azoospermia   Via 1 gene: CFTR 11.74 1
237. AGN 190299 Attention Deficit Disorder with Hyperactivity   Via 1 gene: STS 11.74 1
238. Nicotinic Acids Arteriosclerosis   Via 1 gene: NOS3 11.73 1
239. Streptonigrin Occupational Diseases   Via 1 gene: NQO1 11.72 3
240. PAK 104P Heart Diseases   Via 1 gene: ABCC1 11.69 1
241. Niacinamide Rhabdomyosarcoma, Alveolar   Via 1 gene: FOXO1 11.67 1
242. Meperidine Metabolism, Inborn Errors   Via 1 gene: CES1 11.67 1
243. argatroban Stroke   Via 1 gene: F2 11.66 1
244. Niacinamide Carotid Artery, Internal, Dissection   Via 1 gene: COL1A1 11.66 1
245. Niacinamide Vertebral Artery Dissection   Via 1 gene: COL1A1 11.66 1
246. Niacinamide Hyperostosis, Cortical, Congenital   Via 1 gene: COL1A1 11.66 1
247. Niacinamide OSTEOGENESIS IMPERFECTA, TYPE IIA   Via 1 gene: COL1A1 11.66 1
248. Niacinamide OSTEOGENESIS IMPERFECTA, TYPE I   Via 1 gene: COL1A1 11.66 1
249. Niacinamide OSTEOGENESIS IMPERFECTA, TYPE III   Via 1 gene: COL1A1 11.66 1
250. Nicotinic Acids Myocardial Ischemia   Via 1 gene: NOS3 11.65 1
251. Nicotinic Acids Colonic Neoplasms   Via 1 gene: SLC5A8 11.64 2
252. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile von Hippel-Lindau Disease   Via 1 gene: CCND1 11.63 1
253. Niacin Carcinoma, Pancreatic Ductal   Via 1 gene: HSP70 11.60 1
254. isonicotinamide Metabolic Diseases   Via 1 gene: PPARG 11.52 1
255. Niacinamide CAROTID INTIMAL MEDIAL THICKNESS 1   Via 1 gene: PPARG 11.52 1
256. 6-Aminonicotinamide Carcinoma, Non-Small-Cell Lung   Via 1 gene: MT3 11.50 1
257. arecaidine Female Urogenital Diseases   Via 1 gene: TIMP1 11.49 1
258. LG 100268 Sciatic Neuropathy   Via 1 gene: RXRA 11.45 1
259. Nicotinic Acids Pre-Eclampsia   Via 1 gene: NOS3 11.42 1
260. tazarotene Sarcoma, Synovial   Via 1 gene: BCL2 11.42 1
261. Niacin WAARDENBURG SYNDROME, TYPE 4A   Via 1 gene: EDNRB 11.41 1
262. Streptonigrin Leukemia, Myeloid   Via 1 gene: NQO1 11.39 1
263. Etodolac MISMATCH REPAIR CANCER SYNDROME   Via 1 gene: APC 11.38 1
264. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Neoplasms, Multiple Primary   Via 1 gene: TP53 11.37 1
265. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Histiocytoma, Malignant Fibrous   Via 1 gene: TP53 11.37 1
266. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Hepatoblastoma   Via 1 gene: TP53 11.37 1
267. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Papilloma, Choroid Plexus   Via 1 gene: TP53 11.37 2
268. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Adrenocortical Carcinoma   Via 1 gene: TP53 11.37 1
269. isonicotinamide Hyperalgesia   Via 1 gene: TNFRSF11B 11.35 1
270. Isoniazid Bone Neoplasms   Via 1 gene: PLOD2 11.35 1
271. 6-Aminonicotinamide Urinary Bladder Neoplasms   Via 1 gene: MT3 11.34 1
272. Etodolac Sciatic Neuropathy   Via 1 gene: RXRA 11.31 1
273. Niacin Pancreatic Diseases   Via 1 gene: HMOX1 11.29 1
274. Niacin Cerebral Hemorrhage   Via 1 gene: HMOX1 11.29 1
275. Arecoline Mouth Neoplasms   Via 1 gene: MT1A 11.28 1
276. Niacinamide DIABETES MELLITUS, PERMANENT NEONATAL   Via 1 gene: INS 11.27 1
277. Niflumic Acid Sinusitis   Via 1 gene: CFTR 11.27 1
278. Niacin Hypoglycemia   Via 1 gene: PCK1 11.26 1
279. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Iron Metabolism Disorders   Via 1 gene: TFRC 11.26 2
280. Nicotinic Acids HYPERTENSION, ESSENTIAL   Via 1 gene: NOS3 11.24 1
281. Nicotinic Acids Coronary Artery Disease   Via 1 gene: NOS3 11.24 1
282. Orotic Acid Encephalomyelitis, Autoimmune, Experimental   Via 1 gene: PPARA 11.24 1
283. arecaidine Diabetes Mellitus, Type 1   Via 1 gene: CHRM2 11.24 1
284. LG 100268 Gynecomastia   Via 1 gene: CYP19A1 11.21 1
285. Etodolac Fibromatosis, Aggressive   Via 1 gene: APC 11.20 1
286. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Chondrosarcoma, Mesenchymal   Via 1 gene: BCL2 11.19 1
287. AGN 190299 Head and Neck Neoplasms   Via 1 gene: RARB 11.18 1
288. LG 100268 Lipodystrophy, Familial Partial   Via 1 gene: PPARG 11.17 1
289. LG 100268 LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 2   Via 1 gene: PPARG 11.17 1
290. Arecoline Bone Neoplasms   Via 1 gene: MMP2 11.14 1
291. Arecoline Nasopharyngeal Neoplasms   Via 1 gene: MMP2 11.14 1
292. tazarotene Lymphoma, T-Cell, Cutaneous   Via 1 gene: BAX 11.13 1
293. Kynurenic Acid Schizophrenia   Via 1 gene: CHRNA7 11.12 1
294. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone von Hippel-Lindau Disease   Via 1 gene: CCND1 11.06 1
295. Niacinamide Osteolysis   Via 1 gene: TNFRSF11B 11.02 1
296. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Soft Tissue Neoplasms   Via 1 gene: BCL2 11.01 1
297. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Gallbladder Neoplasms   Via 1 gene: BCL2 11.01 1
298. Niflumic Acid Polycystic Ovary Syndrome   Via 1 gene: CYP19A1 10.99 1
299. Isoniazid Nephrosis   Via 1 gene: DDIT3 10.97 1
300. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone beta-Thalassemia   Via 1 gene: TFRC 10.97 1
301. Niacinamide EHLERS-DANLOS SYNDROME, TYPE VII, AUTOSOMAL DOMINANT   Via 1 gene: COL1A1 10.97 1
302. Niacinamide OSTEOGENESIS IMPERFECTA, TYPE IV   Via 1 gene: COL1A1 10.97 1
303. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Retinoblastoma   Via 1 gene: RB1 10.94 1
304. isonicotinamide Osteoporosis   Via 1 gene: TNFRSF11B 10.94 1
305. Isoniazid Asbestosis   Via 1 gene: GSTT1 10.91 1
306. Isoniazid Raynaud Disease   Via 1 gene: GSTT1 10.91 1
307. Nicotinic Acids Insulin Resistance   Via 1 gene: NOS3 10.87 1
308. LG 100268 von Hippel-Lindau Disease   Via 1 gene: CCND1 10.83 1
309. Niacinamide Lipodystrophy, Familial Partial   Via 1 gene: PPARG 10.83 1
310. Niacinamide LIPODYSTROPHY, FAMILIAL PARTIAL, TYPE 2   Via 1 gene: PPARG 10.83 1
311. Kynurenic Acid Mesothelioma   Via 1 gene: FGF1 10.82 1
312. Niacinamide Neoplasms, Multiple Primary   Via 1 gene: TP53 10.81 1
313. Niacinamide Hepatoblastoma   Via 1 gene: TP53 10.81 1
314. Niacinamide Histiocytoma, Malignant Fibrous   Via 1 gene: TP53 10.81 1
315. Niacinamide Papilloma, Choroid Plexus   Via 1 gene: TP53 10.81 2
316. Niacinamide Adrenocortical Carcinoma   Via 1 gene: TP53 10.81 1
317. Streptonigrin Precursor Cell Lymphoblastic Leukemia-Lymphoma   Via 1 gene: NQO1 10.81 1
318. LG 100268 Critical Illness   Via 1 gene: CYP19A1 10.81 1
319. pyridoxal isonicotinoyl hydrazone Occupational Diseases   Via 1 gene: CYP1A1 10.80 1
320. Niacinamide Tooth Abnormalities   Via 1 gene: RUNX2 10.80 1
321. tazarotene Uterine Cervical Neoplasms   Via 1 gene: RARB 10.79 1
322. tazarotene Attention Deficit Disorder with Hyperactivity   Via 1 gene: STS 10.76 1
323. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Helicobacter Infections   Via 1 gene: TFRC 10.75 2
324. Niacinamide ARTERIOVENOUS MALFORMATIONS OF THE BRAIN   Via 1 gene: IL6 10.75 1
325. lazabemide Autistic Disorder   Via 1 gene: MAOB 10.74 1
326. Kynurenic Acid Pulmonary Fibrosis   Via 1 gene: FGF1 10.73 1
327. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Lymphoma, Follicular   Via 1 gene: BCL2 10.72 2
328. LG 100268 Retinoblastoma   Via 1 gene: RB1 10.72 1
329. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone NASOPHARYNGEAL CARCINOMA, SUSCEPTIBILITY TO, 2   Via 1 gene: TP53 10.67 1
330. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone ADRENOCORTICAL CARCINOMA, HEREDITARY   Via 1 gene: TP53 10.67 1
331. Kynurenic Acid Leukemia   Via 1 gene: FGF1 10.65 1
332. Niflumic Acid Hypogonadism   Via 1 gene: CYP19A1 10.65 1
333. Niflumic Acid Atherosclerosis   Via 1 gene: HSPA1B 10.64 1
334. Niacin Hypogonadism   Via 1 gene: LEPR 10.63 1
335. Niacin Hyperglycemia   Via 1 gene: LEPR 10.63 1
336. Etodolac Rectal Neoplasms   Via 1 gene: APC 10.59 2
337. Arecoline Female Urogenital Diseases   Via 1 gene: TIMP1 10.58 1
338. Meperidine Arthritis, Rheumatoid   Via 1 gene: CES1 10.57 1
339. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Anemia, Iron-Deficiency   Via 1 gene: TFRC 10.57 3
340. Niacinamide EHLERS-DANLOS SYNDROME, TYPE I   Via 1 gene: COL1A1 10.56 1
341. Niflumic Acid Neutropenia   Via 1 gene: UGT1A1 10.55 1
342. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Cecal Neoplasms   Via 1 gene: CCND1 10.53 1
343. Nicotinic Acids Cardiomegaly   Via 1 gene: NOS3 10.52 1
344. LG 100268 Pseudohermaphroditism   Via 1 gene: CYP19A1 10.52 1
345. Niflumic Acid Intestinal Polyps   Via 1 gene: PTGS2 10.51 3
346. Arecoline Intestinal Polyps   Via 1 gene: PTGS2 10.51 3
347. Niacinamide Methemoglobinemia   Via 1 gene: HBA1 10.51 1
348. tazarotene Chondrosarcoma, Mesenchymal   Via 1 gene: BCL2 10.50 1
349. LG 100268 Pituitary ACTH Hypersecretion   Via 1 gene: PPARG 10.48 1
350. Niacinamide Hyperinsulinism   Via 1 gene: INS 10.47 1
351. Etodolac Eye Abnormalities   Via 1 gene: APC 10.43 1
352. Etodolac Hyperlipidemias   Via 1 gene: APC 10.43 1
353. tazarotene Kidney Neoplasms   Via 1 gene: SLC5A5 10.41 1
354. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Intestinal Polyps   Via 1 gene: CCND1 10.38 1
355. Etodolac Sarcoma, Synovial   Via 1 gene: BCL2 10.36 1
356. Niflumic Acid Pancreatitis   Via 1 gene: CFTR 10.36 1
357. tazarotene Gallbladder Neoplasms   Via 1 gene: BCL2 10.32 1
358. tazarotene Soft Tissue Neoplasms   Via 1 gene: BCL2 10.32 1
359. Streptonigrin Multiple Myeloma   Via 1 gene: NQO1 10.29 1
360. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Immunologic Deficiency Syndromes   Via 1 gene: NFKBIA 10.28 1
361. Isoniazid Liposarcoma   Via 1 gene: DDIT3 10.28 1
362. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Keratosis   Via 1 gene: TP53 10.27 1
363. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Demyelinating Diseases   Via 1 gene: TP53 10.27 1
364. Niflumic Acid Arsenic Poisoning   Via 1 gene: HSPA1B 10.26 1
365. Niflumic Acid Rhinitis   Via 1 gene: CFTR 10.26 1
366. Niacinamide Metabolic Syndrome X   Via 1 gene: ADIPOQ 10.26 2
367. Etodolac Leiomyosarcoma   Via 1 gene: PTGS2 10.24 1
368. Etodolac Carcinoma in Situ   Via 1 gene: PTGS2 10.24 2
369. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Osteochondrodysplasias   Via 1 gene: BCL2 10.24 1
370. tazarotene Head and Neck Neoplasms   Via 1 gene: RARB 10.21 1
371. Nicotinic Acids Hernia, Diaphragmatic   Via 1 gene: NOS3 10.20 2
372. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Erectile Dysfunction   Via 1 gene: BCL2L1 10.20 1
373. AGN 190299 Adenocarcinoma   Via 1 gene: RARB 10.16 1
374. Nicotinic Acids Myocardial Infarction   Via 1 gene: NOS3 10.16 1
375. Arecoline Cholangiocarcinoma   Via 1 gene: PTGS2 10.16 1
376. Niflumic Acid ALLERGIC RHINITIS   Via 1 gene: PTGS2 10.16 1
377. Niflumic Acid Cholangiocarcinoma   Via 1 gene: PTGS2 10.16 1
378. Arecoline ALLERGIC RHINITIS   Via 1 gene: PTGS2 10.16 1
379. pyridoxal isonicotinoyl hydrazone Methemoglobinemia   Via 1 gene: CYP1A2 10.16 1
380. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Neurotoxicity Syndromes   Via 1 gene: BCL2L1 10.15 1
381. Niacinamide Pituitary ACTH Hypersecretion   Via 1 gene: PPARG 10.14 1
382. Etodolac Carcinoma, Small Cell   Via 1 gene: BIRC5 10.12 1
383. Niacinamide NASOPHARYNGEAL CARCINOMA, SUSCEPTIBILITY TO, 2   Via 1 gene: TP53 10.12 1
384. Niacinamide ADRENOCORTICAL CARCINOMA, HEREDITARY   Via 1 gene: TP53 10.12 1
385. Etodolac Myocardial Ischemia   Via 1 gene: HGF 10.11 1
386. isonicotinamide Osteoarthritis   Via 1 gene: PPARG 10.11 1
387. Niflumic Acid Cystic Fibrosis   Via 1 gene: CFTR 10.10 4
388. AGN 190299 Carcinoma, Squamous Cell   Via 1 gene: RARB 10.09 1
389. tazarotene Thyroid Neoplasms   Via 1 gene: SLC5A5 10.08 2
390. Niflumic Acid Lymphoma, B-Cell   Via 1 gene: PTGS2 10.06 1
391. Arecoline Lymphoma, B-Cell   Via 1 gene: PTGS2 10.06 1
392. Arecoline Carcinoma, Transitional Cell   Via 1 gene: PTGS2 10.06 3
393. Niflumic Acid Carcinoma, Transitional Cell   Via 1 gene: PTGS2 10.06 3
394. Etodolac Liver Failure, Acute   Via 1 gene: HGF 10.03 1
395. tazarotene Lymphoma, Follicular   Via 1 gene: BCL2 10.03 2
396. Niacin Hirschsprung Disease   Via 1 gene: EDNRB 10.03 1
397. Niacinamide Bone Resorption   Via 1 gene: TNFRSF11B 10.00 2
398. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Li-Fraumeni Syndrome   Via 1 gene: TP53 9.98 2
399. Niflumic Acid Tongue Neoplasms   Via 1 gene: PTGS2 9.98 1
400. Arecoline Tongue Neoplasms   Via 1 gene: PTGS2 9.98 1
401. Streptonigrin Carcinoma, Non-Small-Cell Lung   Via 1 gene: NQO1 9.97 1
402. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Lymphoma, Non-Hodgkin   Via 1 gene: TFRC 9.97 1
403. Niacinamide Neurodegenerative Diseases   Via 1 gene: SIRT1 9.96 2
404. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Cecal Neoplasms   Via 1 gene: CCND1 9.96 1
405. Nicotinic Acids Hypertension   Via 1 gene: NOS3 9.94 2
406. Streptonigrin Obesity   Via 1 gene: NQO1 9.93 1
407. LG 100268 Metabolic Diseases   Via 1 gene: PPARG 9.92 1
408. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Retinal Degeneration   Via 1 gene: BCL2 9.91 1
409. Niacin Mastocytosis, Systemic   Via 1 gene: HMOX1 9.91 1
410. tazarotene Glioma   Via 1 gene: SLC5A5 9.90 1
411. LG 100268 Pancreatic Neoplasms   Via 1 gene: NR5A2 9.90 1
412. Niacinamide Lymphoma, T-Cell, Cutaneous   Via 1 gene: BAX 9.88 1
413. Niacinamide Drug Toxicity   Via 1 gene: IGFBP1 9.83 1
414. Niflumic Acid Adenomatous Polyposis Coli   Via 1 gene: PTGS2 9.82 1
415. Arecoline Adenomatous Polyposis Coli   Via 1 gene: PTGS2 9.82 1
416. Isoniazid Anemia, Sideroblastic   Via 1 gene: SOD2 9.81 1
417. N,N-di-n-hexyl-2-(4-fluorophenyl)indole-3-acetamide Sepsis   Via 1 gene: CASP3 9.81 1
418. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Intestinal Polyps   Via 1 gene: CCND1 9.80 1
419. pyridoxal isonicotinoyl hydrazone Kidney Neoplasms   Via 1 gene: CYP1A1 9.77 1
420. Kynurenic Acid Autistic Disorder   Via 1 gene: CHRNA7 9.75 1
421. LG 100268 Cecal Neoplasms   Via 1 gene: CCND1 9.74 1
422. Arecoline Liver Cirrhosis   Via 1 gene: MMP2 9.73 1
423. tazarotene Erectile Dysfunction   Via 1 gene: BCL2 9.71 1
424. Niacinamide Demyelinating Diseases   Via 1 gene: TP53 9.71 1
425. Niacinamide Keratosis   Via 1 gene: TP53 9.71 1
426. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Carcinoma   Via 1 gene: BCL2L1 9.71 1
427. Niflumic Acid Oral Submucous Fibrosis   Via 1 gene: PTGS2 9.69 1
428. Niacin Hypertension, Pulmonary   Via 1 gene: EDNRB 9.68 1
429. Niacin Lung Injury   Via 1 gene: HMOX1 9.68 1
430. Meperidine Liver Cirrhosis, Experimental   Via 1 gene: CES2 9.66 1
431. Arecoline Neoplasm Metastasis   Via 1 gene: MMP2 9.63 1
432. Arecoline Diabetes Mellitus   Via 1 gene: PTGS2 9.63 1
433. Niflumic Acid Diabetes Mellitus   Via 1 gene: PTGS2 9.63 1
434. Niacinamide Diabetes Mellitus   Via 1 gene: ADIPOQ 9.63 1
435. isonicotinamide Glioma   Via 1 gene: PPARG 9.62 1
436. Arecoline Glioblastoma   Via 1 gene: MMP2 9.61 1
437. LG 100268 Polycystic Ovary Syndrome   Via 1 gene: CYP19A1 9.61 1
438. Niflumic Acid Infertility, Male   Via 1 gene: CFTR 9.59 2
439. Niacinamide Metabolic Diseases   Via 1 gene: PPARG 9.58 1
440. LG 100268 Intestinal Polyps   Via 1 gene: CCND1 9.58 1
441. Nicotinic Acids Alzheimer Disease   Via 1 gene: NOS3 9.58 2
442. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Carcinoma, Small Cell   Via 1 gene: TP53 9.58 1
443. Arecoline Carcinoma   Via 1 gene: PTGS2 9.57 1
444. Niflumic Acid Carcinoma   Via 1 gene: PTGS2 9.57 1
445. Niflumic Acid Coronary Artery Disease   Via 1 gene: PTGS2 9.57 1
446. Arecoline Coronary Artery Disease   Via 1 gene: PTGS2 9.57 1
447. Nicotinic Acids Neoplasms   Via 1 gene: NOS3 9.57 1
448. tazarotene Osteochondrodysplasias   Via 1 gene: BCL2 9.55 1
449. Etodolac Mental Retardation   Via 1 gene: APC 9.54 1
450. Etodolac Heart Failure   Via 1 gene: ITGB1 9.53 1
451. Niflumic Acid Duodenal Ulcer   Via 1 gene: PTGS2 9.52 1
452. Arecoline Duodenal Ulcer   Via 1 gene: PTGS2 9.52 1
453. tazarotene Ovarian Neoplasms   Via 1 gene: SLC5A5 9.47 1
454. Niacinamide Insulin Resistance   Via 1 gene: INS1 9.46 1
455. Etodolac Chondrosarcoma, Mesenchymal   Via 1 gene: BCL2 9.45 1
456. Isoniazid Metabolism, Inborn Errors   Via 1 gene: NAT2 9.44 1
457. Niacinamide Hyperalgesia   Via 1 gene: TNFRSF11B 9.43 1
458. Etodolac Medulloblastoma   Via 1 gene: APC 9.43 1
459. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Carotid Artery Diseases   Via 1 gene: TP53 9.42 1
460. Niacinamide Li-Fraumeni Syndrome   Via 1 gene: TP53 9.42 2
461. LG 100268 Osteosarcoma   Via 1 gene: RB1 9.42 1
462. isonicotinamide Obesity   Via 1 gene: PPARG 9.38 1
463. Niacinamide Arthritis, Juvenile Rheumatoid   Via 1 gene: IL6 9.36 1
464. Niacinamide Sarcoma, Kaposi   Via 1 gene: IL6 9.36 1
465. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Muscular Dystrophy, Facioscapulohumeral   Via 1 gene: CDKN1A 9.35 1
466. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile HIV Infections   Via 1 gene: BIRC2 9.35 1
467. Niacin Pulmonary Emphysema   Via 1 gene: HMOX1 9.35 2
468. Niacin Carotid Artery Diseases   Via 1 gene: HMOX1 9.35 1
469. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Neurotoxicity Syndromes   Via 1 gene: BCL2L1 9.34 1
470. Niacin Cardiomyopathy, Dilated   Via 1 gene: TPM1 9.30 1
471. Niacinamide Intestinal Polyps   Via 1 gene: JUN 9.29 1
472. Streptonigrin Liver Diseases   Via 1 gene: NQO1 9.28 2
473. pyridoxal isonicotinoyl hydrazone Liver Neoplasms, Experimental   Via 1 gene: CYP1A2 9.27 1
474. LG 100268 Hypogonadism   Via 1 gene: CYP19A1 9.27 1
475. Etodolac Soft Tissue Neoplasms   Via 1 gene: BCL2 9.27 1
476. Etodolac Gallbladder Neoplasms   Via 1 gene: BCL2 9.27 1
477. Niacin Obesity   Via 1 gene: UCP1 9.25 1
478. AGN 190299 Stomach Neoplasms   Via 1 gene: RARB 9.25 1
479. Etodolac Mesothelioma   Via 1 gene: APC 9.23 1
480. tazarotene Carcinoma   Via 1 gene: BCL2 9.22 1
481. tazarotene Retinal Degeneration   Via 1 gene: BCL2 9.22 1
482. Niacin Pneumonia   Via 1 gene: HMOX1 9.21 1
483. AGN 190299 Lung Neoplasms   Via 1 gene: RARB 9.21 1
484. Niflumic Acid Cardiomyopathies   Via 1 gene: PTGS2 9.20 1
485. Arecoline Cardiomyopathies   Via 1 gene: PTGS2 9.20 1
486. tazarotene Neoplasms   Via 1 gene: SLC5A5 9.20 1
487. tazarotene Adenocarcinoma   Via 1 gene: RARB 9.19 1
488. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Nasopharyngeal Neoplasms   Via 1 gene: TP53 9.17 1
489. 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone Carcinoma, Transitional Cell   Via 1 gene: CDKN1A 9.15 1
490. Arecoline Amyotrophic Lateral Sclerosis   Via 1 gene: PTGS2 9.13 1
491. Arecoline Kidney Neoplasms   Via 1 gene: PTGS2 9.13 1
492. Niflumic Acid Amyotrophic Lateral Sclerosis   Via 1 gene: PTGS2 9.13 1
493. Niflumic Acid Kidney Neoplasms   Via 1 gene: PTGS2 9.13 1
494. Etodolac Cardiomyopathy, Dilated   Via 1 gene: ITGB1 9.13 1
495. tazarotene Carcinoma, Squamous Cell   Via 1 gene: RARB 9.12 1
496. 2-amino-6-(2-(cyclopropylmethoxy)-6-hydroxyphenyl)-4-piperidin-4-yl nicotinonitrile Mammary Neoplasms, Experimental   Via 1 gene: XIAP 9.12 1
497. tazarotene Sepsis   Via 1 gene: CASP3 9.11 1
498. arecaidine Liver Cirrhosis, Experimental   Via 1 gene: TIMP1 9.11 3
499. Etodolac Neuroblastoma   Via 1 gene: HGF 9.09 1
500. isonicotinamide Diabetes Mellitus, Type 2   Via 1 gene: PPARG 9.08 1
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