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ChemicalChemical: Chlorpyrifos

The following diseases are associated with Chlorpyrifos or at least one of its descendants. Each association is direct (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

Showing 1–331 of 331
  Chemical Disease Direct Evidence Inference Network Inference Score References
1. Chlorpyrifos Respiratory Tract Diseases M   2
2. Chlorpyrifos Sex Chromosome Aberrations M   1
3. Chlorpyrifos Neurotoxicity Syndromes M   1
4. Chlorpyrifos Respiratory Sounds M   3
5. Chlorpyrifos Liver Diseases M Via 3 genes: ALPL; CYP1A2; SOD1 17.07 4
6. Chlorpyrifos Agricultural Workers' Diseases M Via 1 gene: PON1 6.50 4
7. Chlorpyrifos Autistic Disorder   Via 23 genes: ADRB2; BDNF; CAT; CHRNA7; CHRNB2; COMT; GPX1; GRIA1; GRIK2; GRIN2A; GSTM1; HTR1B; HTR1D; HTR2A; HTR5A; IGF1; IL6; NRCAM; NTF3; PON1; SLC6A4; SLC6A8; WNT2 170.93 24
8. Chlorpyrifos Prostatic Neoplasms   Via 19 genes: ADRB2; CASP9; COMT; CYP1A1; CYP3A4; CYP3A5; ESR1; FGFR4; GSTK1; GSTM1; GSTM3; GSTO1; GSTT1; IGF1; IL6; PON1; SOD2; TGFB1; TP53 108.69 27
9. Chlorpyrifos Breast Neoplasms   Via 14 genes: COMT; CYP1A1; CYP3A4; ESR1; FGFR2; FOS; GPX1; GPX2; GPX4; IGF1; IL1B; IL6; TP53; WNT10B 80.51 21
10. Chlorpyrifos Schizophrenia   Via 10 genes: CHRNA7; COMT; DRD2; DRD4; GRIN2B; HTR2A; IL1B; SLC6A4; TP53; TPH1 79.06 4
11. Chlorpyrifos Parkinson Disease   Via 9 genes: CYP2D6; DBH; DRD4; FGF20; GPX1; GSTA4; SLC18A2; SLC6A3; SOD1 71.98 5
12. Chlorpyrifos Lung Neoplasms   Via 11 genes: CHRNA5; CHRNB4; ESR1; FOS; GPX1; GSTP2; MAPK1; MAPK3; PON1; TGFB1; TP53 67.36 16
13. Chlorpyrifos Liver Cirrhosis, Experimental   Via 11 genes: ABCB1; ACHE; CYP1A2; FGF2; GOT1; GPT; GSTA2; GSTM1; IGF1; IL1B; TGFB1 63.82 9
14. Chlorpyrifos TOBACCO ADDICTION, SUSCEPTIBILITY TO   Via 6 genes: BDNF; CHRNA5; CHRNA6; CHRNB3; CYP2B6; SLC6A3 59.38 4
15. Chlorpyrifos Carcinoma, Hepatocellular   Via 7 genes: COMT; CYP1A1; ESR1; FOS; IL6; TGFB1; TP53 38.03 7
16. Chlorpyrifos Hernia, Diaphragmatic   Via 5 genes: FGF18; FGF2; IGF1; IL6; TGFB1 34.65 4
17. Chlorpyrifos Mesothelioma   Via 5 genes: ESR1; FGF1; FGF2; GSTM1; SOD2 34.28 5
18. Chlorpyrifos Pulmonary Fibrosis   Via 5 genes: FGF1; FGF2; IL1B; IL6; TGFB1 32.50 5
19. Chlorpyrifos Epilepsy   Via 4 genes: ABCB1; ADRA2A; CHRNA7; GPX1 30.37 5
20. Chlorpyrifos Drug-Induced Liver Injury   Via 5 genes: GSTT1; IL1B; IL6; PON1; SOD3 30.14 5
21. Chlorpyrifos Stomach Neoplasms   Via 5 genes: BDNF; FGFR2; IL1B; MX1; SOD2 29.82 4
22. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Arthritis, Rheumatoid   Via 3 genes: ADRBK1; CES1; PON1 28.42 3
23. Chlorpyrifos Obsessive-Compulsive Disorder   Via 3 genes: BDNF; HTR2A; SLC6A4 27.92 2
24. Chlorpyrifos Myocardial Ischemia   Via 3 genes: ADRB1; ADRB2; FGF2 25.21 3
25. Chlorpyrifos Attention Deficit Disorder with Hyperactivity   Via 3 genes: COMT; DRD4; SLC6A3 24.72 3
26. Chlorpyrifos Neuroblastoma   Via 3 genes: BCHE; NTRK1; NTRK2 24.39 3
27. Chlorpyrifos Diabetes Mellitus, Experimental   Via 3 genes: ADRA1A; ADRB3; CHRM2 24.39 3
28. Chlorpyrifos Cleft Lip   Via 3 genes: FGF2; FGF9; FGFR2 24.31 1
29. Chlorpyrifos Asthma   Via 4 genes: ADRB2; CAT; GSTM1; TGFB1 23.83 5
30. Chlorpyrifos Alzheimer Disease   Via 4 genes: BDNF; CHRNB2; ESR1; IL1B 23.70 3
31. Chlorpyrifos MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE   Via 2 genes: CHRND; CHRNG 23.61 1
32. Chlorpyrifos Diabetes Mellitus   Via 3 genes: ADRB1; CAT; PON1 22.95 3
33. Chlorpyrifos MYASTHENIC SYNDROME, CONGENITAL, FAST-CHANNEL   Via 2 genes: CHRND; CHRNE 22.89 1
34. Chlorpyrifos Heart Failure   Via 3 genes: ADRA2C; ADRB1; IL6 22.47 3
35. Chlorpyrifos Female Urogenital Diseases   Via 3 genes: ESR1; IGF1; WNT5A 22.43 1
36. Chlorpyrifos MYASTHENIC SYNDROME, CONGENITAL, SLOW-CHANNEL   Via 2 genes: CHRND; CHRNE 22.20 1
37. Chlorpyrifos Osteosarcoma   Via 3 genes: CYP3A4; NR1I2; TP53 21.98 4
38. Chlorpyrifos Cleft Palate   Via 3 genes: FGF2; FGF9; FGFR2 21.90 1
39. Chlorpyrifos Osteoporosis, Postmenopausal   Via 3 genes: CAT; IL1B; IL6 21.02 2
40. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hypercholesterolemia   Via 2 genes: CES1; PON1 20.42 2
41. Chlorpyrifos Obesity   Via 3 genes: ADRB2; ADRB3; GPX1 20.36 4
42. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Metabolism, Inborn Errors   Via 2 genes: BCHE; CES1 20.10 2
43. Chlorpyrifos Liver Cirrhosis   Via 3 genes: FGF2; FGFR2; IL6 20.04 3
44. Chlorpyrifos Sepsis   Via 3 genes: MAPK1; MAPK3; TGFB1 19.95 2
45. Chlorpyrifos Anorexia Nervosa   Via 2 genes: BDNF; HTR2A 19.73 1
46. Chlorpyrifos Hypotension   Via 2 genes: GRIA1; GRIN2B 19.06 1
47. Chlorpyrifos Head and Neck Neoplasms   Via 3 genes: GPX1; MAPK1; MAPK3 19.00 2
48. Chlorpyrifos Leukemia   Via 3 genes: ESR1; FGF1; GSTM1 18.83 4
49. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Poisoning   Via 2 genes: ACHE; PON1 18.82 2
50. Chlorpyrifos Colorectal Neoplasms   Via 3 genes: GPX4; GRIN2A; TP53 18.57 9
51. Chlorpyrifos Precursor Cell Lymphoblastic Leukemia-Lymphoma   Via 2 genes: BCR; DKK3 17.62 2
52. Chlorpyrifos Raynaud Disease   Via 2 genes: GSTM1; GSTT1 17.53 1
53. Chlorpyrifos Skin Diseases   Via 3 genes: GSTM1; IL1B; SOD2 17.47 2
54. Chlorpyrifos Alcoholism   Via 2 genes: HTR2A; SLC6A4 17.43 2
55. Chlorpyrifos Down Syndrome   Via 2 genes: GSTM2; NTF3 17.16 2
56. Chlorpyrifos Anxiety Disorders   Via 2 genes: SLC6A3; SLC6A4 17.02 2
57. Chlorpyrifos Arsenic Poisoning   Via 3 genes: IL1B; SOD2; TP53 16.96 2
58. Chlorpyrifos Urinary Bladder Neoplasms   Via 3 genes: ESR1; GSTM1; TP53 16.56 4
59. Chlorpyrifos Hyperlipidemias   Via 2 genes: ADRB2; ADRB3 16.42 1
60. Chlorpyrifos Bipolar Disorder   Via 2 genes: BDNF; NTRK2 16.26 1
61. Chlorpyrifos Adenocarcinoma   Via 3 genes: ESR1; TGFB1; TP53 15.98 4
62. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Drug-Induced Liver Injury   Via 2 genes: ALB; PON1 15.71 2
63. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Liver Cirrhosis, Experimental   Via 2 genes: ACHE; CNR1 15.26 2
64. Chlorpyrifos Hepatitis C   Via 2 genes: CYP2B1; CYP3A4 15.02 1
65. Chlorpyrifos Occupational Diseases   Via 2 genes: CYP1A1; CYP2D6 14.97 1
66. Chlorpyrifos Coronary Artery Disease   Via 2 genes: GPX1; PON1 14.52 2
67. Chlorpyrifos Entamoebiasis   Via 2 genes: IL1B; IL6 14.29 1
68. Chlorpyrifos Oral Submucous Fibrosis   Via 2 genes: FGF2; TGFB1 14.27 1
69. Chlorpyrifos Hypertension   Via 2 genes: ADRB1; SOD3 14.15 2
70. Chlorpyrifos Mental Retardation   Via 2 genes: BDNF; FGFR2 14.12 2
71. Chlorpyrifos Methemoglobinemia   Via 2 genes: CYP1A2; HBB 14.06 2
72. Chlorpyrifos Arthritis, Rheumatoid   Via 2 genes: ADRBK1; PON1 13.98 2
73. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 8, WITH EXOCRINE DYSFUNCTION   Via 1 gene: CEL 13.72 1
74. Chlorpyrifos Poisoning   Via 2 genes: ACHE; PON1 13.72 2
75. Chlorpyrifos Pulmonary Disease, Chronic Obstructive   Via 2 genes: TGFB1; TP53 13.64 2
76. chlorpyrifos-methyl Muscle Spasticity   Via 1 gene: CNR1 13.61 1
77. Chlorpyrifos Migraine Disorders   Via 2 genes: ESR1; HTR2A 13.53 3
78. Chlorpyrifos Cardiomyopathy, Dilated   Via 2 genes: ADRB1; GPX1 13.49 2
79. Chlorpyrifos Neoplasm Metastasis   Via 2 genes: PDE5A; TP53 13.45 2
80. Chlorpyrifos Berylliosis   Via 2 genes: IL6; TGFB1 13.42 3
81. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Deficiency Diseases   Via 1 gene: CES1 12.79 1
82. Chlorpyrifos Fever   Via 2 genes: IL1B; IL6 12.61 1
83. Chlorpyrifos Glioblastoma   Via 2 genes: BCHE; IL1B 12.61 2
84. Chlorpyrifos Diabetes Mellitus, Type 1   Via 2 genes: CAT; CHRM2 12.59 2
85. Chlorpyrifos Amyotrophic Lateral Sclerosis   Via 2 genes: SOD1; TP53 12.50 8
86. Chlorpyrifos MULTIPLE PTERYGIUM SYNDROME, ESCOBAR VARIANT   Via 1 gene: CHRNG 12.48 1
87. Chlorpyrifos NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B   Via 1 gene: GRM6 12.48 1
88. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Persian Gulf Syndrome   Via 1 gene: PON1 12.35 1
89. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5   Via 1 gene: PON1 12.35 1
90. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Prostatic Neoplasms   Via 2 genes: CYP1A1; PON1 12.24 4
91. Chlorpyrifos Atherosclerosis   Via 2 genes: ESR1; PON1 12.22 4
92. Chlorpyrifos Hydrocephalus   Via 1 gene: HYDIN 12.19 2
93. Chlorpyrifos SPLIT-HAND/FOOT MALFORMATION 6   Via 1 gene: WNT10B 12.10 1
94. Chlorpyrifos Carcinoma, Squamous Cell   Via 2 genes: GPX1; GSTT1 12.08 2
95. chlorpyrifos-methyl Multiple Sclerosis   Via 1 gene: CNR1 11.92 1
96. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate ZINC, ELEVATED PLASMA   Via 1 gene: ALB 11.83 1
97. Chlorpyrifos GLYCOGEN STORAGE DISEASE OF HEART, LETHAL CONGENITAL   Via 1 gene: PRKAG2 11.77 1
98. Chlorpyrifos Wolff-Parkinson-White Syndrome   Via 1 gene: PRKAG2 11.77 1
99. Chlorpyrifos CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 6   Via 1 gene: PRKAG2 11.77 1
100. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Opioid-Related Disorders   Via 1 gene: CES1 11.69 1
101. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Cocaine-Related Disorders   Via 1 gene: CES1 11.69 2
102. Chlorpyrifos CHARCOT-MARIE-TOOTH DISEASE, DOMINANT INTERMEDIATE D   Via 1 gene: MPZ 11.64 1
103. Chlorpyrifos CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2I   Via 1 gene: MPZ 11.64 1
104. Chlorpyrifos CHARCOT-MARIE-TOOTH DISEASE, DEMYELINATING, TYPE 1B   Via 1 gene: MPZ 11.64 1
105. Chlorpyrifos MENTAL RETARDATION, AUTOSOMAL RECESSIVE 6   Via 1 gene: GRIK2 11.64 1
106. Chlorpyrifos CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2J   Via 1 gene: MPZ 11.64 1
107. Chlorpyrifos VENTRICULAR TACHYCARDIA, FAMILIAL   Via 1 gene: GNAI2 11.58 1
108. Chlorpyrifos NOVELTY SEEKING PERSONALITY TRAIT   Via 1 gene: DRD4 11.52 1
109. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Muscle Spasticity   Via 1 gene: CNR1 11.47 1
110. Chlorpyrifos Inflammatory Bowel Diseases   Via 2 genes: ABCB1; IL6 11.46 2
111. Chlorpyrifos Osteoporosis   Via 2 genes: IL6; TGFB1 11.40 3
112. Chlorpyrifos Orthostatic Intolerance   Via 1 gene: SLC6A2 11.38 1
113. Chlorpyrifos CREATINE DEFICIENCY SYNDROME, X-LINKED   Via 1 gene: SLC6A8 11.38 2
114. Chlorpyrifos Pancreatic Neoplasms   Via 2 genes: CYP2B1; TP53 11.28 3
115. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Neuroectodermal Tumors, Primitive   Via 1 gene: PON1 11.26 1
116. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hyperlipoproteinemias   Via 1 gene: PON1 11.26 1
117. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Coronary Vasospasm   Via 1 gene: PON1 11.26 1
118. Chlorpyrifos MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH EPISODIC APNEA   Via 1 gene: CHAT 11.26 1
119. Chlorpyrifos Esophageal Neoplasms   Via 2 genes: GSTT1; TP53 11.24 2
120. Chlorpyrifos MULTIPLE SYNOSTOSES SYNDROME 3   Via 1 gene: FGF9 11.11 1
121. Chlorpyrifos Psoriasis   Via 2 genes: IL6; TP53 11.09 2
122. Chlorpyrifos HYPOPHOSPHATEMIC RICKETS, AUTOSOMAL DOMINANT   Via 1 gene: FGF23 11.08 1
123. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hyperthyroidism   Via 1 gene: PON1 10.97 1
124. Chlorpyrifos NEUROPATHY, CONGENITAL HYPOMYELINATING   Via 1 gene: MPZ 10.95 1
125. Chlorpyrifos ROUSSY-LEVY HEREDITARY AREFLEXIC DYSTASIA   Via 1 gene: MPZ 10.95 1
126. Chlorpyrifos CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2E   Via 1 gene: NEFL 10.94 1
127. Chlorpyrifos CHARCOT-MARIE-TOOTH DISEASE, DEMYELINATING, TYPE 1F   Via 1 gene: NEFL 10.94 1
128. Chlorpyrifos NEUROTROPHIC TYROSINE KINASE, RECEPTOR, TYPE 2   Via 1 gene: NTRK2 10.91 1
129. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Substance-Related Disorders   Via 1 gene: FAAH 10.84 1
130. Chlorpyrifos Hereditary Sensory and Autonomic Neuropathies   Via 1 gene: NTRK1 10.84 1
131. Chlorpyrifos THYROID CARCINOMA, FAMILIAL MEDULLARY   Via 1 gene: NTRK1 10.84 1
132. Chlorpyrifos Liver Neoplasms, Experimental   Via 2 genes: CYP1A2; TP53 10.84 2
133. Chlorpyrifos DOPAMINE BETA-HYDROXYLASE DEFICIENCY, CONGENITAL   Via 1 gene: DBH 10.83 1
134. Chlorpyrifos GLUTATHIONE SYNTHETASE DEFICIENCY OF ERYTHROCYTES, HEMOLYTIC ANEMIA DUE TO   Via 1 gene: GSS 10.81 1
135. Chlorpyrifos GLUTATHIONE SYNTHETASE DEFICIENCY   Via 1 gene: GSS 10.81 1
136. Chlorpyrifos Leukemia, Lymphocytic, Chronic, B-Cell   Via 2 genes: IL6; TP53 10.79 2
137. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Glomerulonephritis, Membranoproliferative   Via 1 gene: PON1 10.75 1
138. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hyperthyroxinemia   Via 1 gene: ALB 10.73 1
139. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Stevens-Johnson Syndrome   Via 1 gene: ALB 10.73 1
140. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate HIV Seropositivity   Via 1 gene: ALB 10.73 1
141. Chlorpyrifos PARKINSONISM-DYSTONIA, INFANTILE   Via 1 gene: SLC6A3 10.62 1
142. Chlorpyrifos Tic Disorders   Via 1 gene: SLC6A3 10.62 1
143. Chlorpyrifos EPILEPSY, NOCTURNAL FRONTAL LOBE, TYPE 3   Via 1 gene: CHRNB2 10.62 1
144. Chlorpyrifos RESTING HEART RATE   Via 1 gene: ADRB1 10.57 1
145. Chlorpyrifos NEUROPATHY, HEREDITARY SENSORY AND AUTONOMIC, TYPE V   Via 1 gene: NGF 10.54 1
146. Chlorpyrifos MYASTHENIC SYNDROME, CONGENITAL, ASSOCIATED WITH ACETYLCHOLINE RECEPTOR DEFICIENCY   Via 1 gene: CHRNE 10.40 1
147. Chlorpyrifos HYPOPHOSPHATASIA, CHILDHOOD   Via 1 gene: ALPL 10.37 1
148. Chlorpyrifos HYPOPHOSPHATASIA, ADULT   Via 1 gene: ALPL 10.37 1
149. Chlorpyrifos HYPOPHOSPHATASIA, INFANTILE   Via 1 gene: ALPL 10.37 1
150. Chlorpyrifos BETA THALASSEMIA, DOMINANT INCLUSION BODY TYPE   Via 1 gene: HBB 10.31 1
151. Chlorpyrifos SEGAWA SYNDROME, AUTOSOMAL RECESSIVE   Via 1 gene: TH 10.28 1
152. Chlorpyrifos HYPERTROPHIC NEUROPATHY OF DEJERINE-SOTTAS   Via 1 gene: MPZ 10.27 1
153. Chlorpyrifos CUTIS GYRATA SYNDROME OF BEARE AND STEVENSON   Via 1 gene: FGFR2 10.20 2
154. Chlorpyrifos SCAPHOCEPHALY, MAXILLARY RETRUSION, AND MENTAL RETARDATION   Via 1 gene: FGFR2 10.20 1
155. Chlorpyrifos Ankylosis   Via 1 gene: FGFR2 10.20 1
156. Chlorpyrifos Plagiocephaly, Nonsynostotic   Via 1 gene: FGFR2 10.20 1
157. Chlorpyrifos Diabetic Neuropathies   Via 1 gene: NTF3 10.19 1
158. Chlorpyrifos Diabetes Mellitus, Type 2   Via 2 genes: CAT; IL6 10.16 2
159. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hepatitis C   Via 1 gene: CYP2B1 10.15 1
160. Chlorpyrifos Alexander Disease   Via 1 gene: GFAP 10.10 1
161. Chlorpyrifos Liver Neoplasms   Via 2 genes: ESR1; TP53 10.06 3
162. Chlorpyrifos TUMORAL CALCINOSIS, HYPERPHOSPHATEMIC, FAMILIAL   Via 1 gene: FGF23 10.00 1
163. Chlorpyrifos DRUG METABOLISM, POOR, CYP2C19-RELATED   Via 1 gene: CYP2C19 9.99 1
164. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Diabetes Mellitus, Experimental   Via 1 gene: CHRM2 9.97 1
165. Chlorpyrifos DRUG METABOLISM, POOR, CYP2D6-RELATED   Via 1 gene: CYP2D6 9.96 1
166. Chlorpyrifos Heart Valve Diseases   Via 1 gene: HTR2B 9.86 1
167. Chlorpyrifos STROKE, ISCHEMIC   Via 1 gene: PRKCH 9.82 1
168. Chlorpyrifos MYOCLONIC DYSTONIA   Via 1 gene: DRD2 9.82 1
169. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hyperlipoproteinemia Type II   Via 1 gene: PON1 9.79 2
170. chlorpyrifos-methyl Liver Cirrhosis, Experimental   Via 1 gene: CNR1 9.79 1
171. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Multiple Sclerosis   Via 1 gene: CNR1 9.79 1
172. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Nephrotic Syndrome   Via 1 gene: ALB 9.76 1
173. Chlorpyrifos Ovarian Neoplasms   Via 2 genes: MAPK1; MAPK3 9.75 1
174. Chlorpyrifos Persian Gulf Syndrome   Via 1 gene: PON1 9.75 1
175. Chlorpyrifos MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5   Via 1 gene: PON1 9.75 1
176. Chlorpyrifos Lymphoma, Large-Cell, Anaplastic   Via 1 gene: HSP90AA1 9.72 1
177. Chlorpyrifos GLUTATHIONE REDUCTASE;GSR GLUTATHIONE REDUCTASE, HEMOLYTIC ANEMIA DUE TO DEFICIENCY OF, IN RED   Via 1 gene: GSR 9.64 1
178. Chlorpyrifos Pheochromocytoma   Via 1 gene: CHGA 9.60 1
179. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Hyperhomocysteinemia   Via 1 gene: PON1 9.59 1
180. Chlorpyrifos MAJOR AFFECTIVE DISORDER 1   Via 1 gene: SLC6A3 9.54 1
181. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Diabetes Mellitus   Via 1 gene: PON1 9.53 1
182. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Neuroblastoma   Via 1 gene: BCHE 9.52 1
183. Chlorpyrifos Craniofacial Dysostosis   Via 1 gene: FGFR2 9.52 2
184. Chlorpyrifos Antley-Bixler Syndrome Phenotype   Via 1 gene: FGFR2 9.52 2
185. Chlorpyrifos Craniosynostoses   Via 1 gene: FGFR2 9.52 3
186. Chlorpyrifos JACKSON-WEISS SYNDROME   Via 1 gene: FGFR2 9.52 1
187. Chlorpyrifos INSULIN-LIKE GROWTH FACTOR I DEFICIENCY   Via 1 gene: IGF1 9.52 1
188. Chlorpyrifos MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 6   Via 1 gene: SOD2 9.49 1
189. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Coronary Artery Disease   Via 1 gene: PON1 9.47 1
190. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Brain Neoplasms   Via 1 gene: PON1 9.47 1
191. Chlorpyrifos Neurobehavioral Manifestations   Via 1 gene: CHRNA7 9.47 1
192. Chlorpyrifos Neoplasms, Second Primary   Via 1 gene: GSTM1 9.40 1
193. Chlorpyrifos Hypokalemia   Via 1 gene: ADRB2 9.37 1
194. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Coronary Disease   Via 1 gene: PON1 9.32 2
195. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Glioblastoma   Via 1 gene: BCHE 9.31 1
196. Chlorpyrifos Colonic Neoplasms   Via 2 genes: IL1B; TP53 9.31 3
197. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Respiratory Distress Syndrome, Adult   Via 1 gene: ALB 9.27 1
198. Chlorpyrifos Carcinoma, Pancreatic Ductal   Via 1 gene: HSP70 9.26 1
199. Chlorpyrifos HEINZ BODY ANEMIAS   Via 1 gene: HBB 9.23 1
200. Chlorpyrifos Bulimia Nervosa   Via 1 gene: BDNF 9.22 2
201. Chlorpyrifos WILMS TUMOR, ANIRIDIA, GENITOURINARY ANOMALIES, MENTAL RETARDATION, AND OBESITY SYNDROME   Via 1 gene: BDNF 9.22 1
202. Chlorpyrifos EPILEPSY, IDIOPATHIC GENERALIZED   Via 1 gene: CHRNA7 9.15 1
203. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Diabetes Mellitus, Type 1   Via 1 gene: CHRM2 9.13 1
204. Chlorpyrifos Hamartoma Syndrome, Multiple   Via 1 gene: FGFR2 9.12 1
205. Chlorpyrifos LACRIMOAURICULODENTODIGITAL SYNDROME   Via 1 gene: FGFR2 9.12 1
206. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Occupational Diseases   Via 1 gene: CYP1A1 9.07 1
207. Chlorpyrifos Camurati-Engelmann Syndrome   Via 1 gene: TGFB1 9.06 1
208. Chlorpyrifos Asperger Syndrome   Via 1 gene: SLC6A4 9.05 1
209. Chlorpyrifos Acatalasia   Via 1 gene: CAT 9.04 1
210. Chlorpyrifos Gliosarcoma   Via 1 gene: CYP2B6 8.98 1
211. Chlorpyrifos Thalassemia   Via 1 gene: HBB 8.95 1
212. Chlorpyrifos Polycythemia Vera   Via 1 gene: HBB 8.95 1
213. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Agricultural Workers' Diseases   Via 1 gene: PON1 8.90 1
214. Chlorpyrifos Motor Skills Disorders   Via 1 gene: FGFR2 8.84 1
215. Chlorpyrifos Skin Abnormalities   Via 1 gene: FGFR2 8.84 1
216. Chlorpyrifos Acrocephalosyndactylia   Via 1 gene: FGFR2 8.84 7
217. Chlorpyrifos Mammary Neoplasms, Animal   Via 1 gene: COMT 8.81 1
218. Chlorpyrifos Leukemia, Myelogenous, Chronic, BCR-ABL Positive   Via 1 gene: BCR 8.81 1
219. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Cardiovascular Diseases   Via 1 gene: PON1 8.76 1
220. Chlorpyrifos Anemia, Sickle Cell   Via 1 gene: HBB 8.73 1
221. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Atherosclerosis   Via 1 gene: PON1 8.71 3
222. Chlorpyrifos Papilloma, Choroid Plexus   Via 1 gene: TP53 8.70 2
223. Chlorpyrifos Adrenocortical Carcinoma   Via 1 gene: TP53 8.70 1
224. Chlorpyrifos Neoplasms, Multiple Primary   Via 1 gene: TP53 8.70 1
225. Chlorpyrifos Hepatoblastoma   Via 1 gene: TP53 8.70 1
226. Chlorpyrifos Histiocytoma, Malignant Fibrous   Via 1 gene: TP53 8.70 1
227. Chlorpyrifos Coronary Vasospasm   Via 1 gene: PON1 8.66 1
228. Chlorpyrifos Neuroectodermal Tumors, Primitive   Via 1 gene: PON1 8.66 1
229. Chlorpyrifos Hyperlipoproteinemias   Via 1 gene: PON1 8.66 1
230. Chlorpyrifos ARTERIOVENOUS MALFORMATIONS OF THE BRAIN   Via 1 gene: IL6 8.64 1
231. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Depressive Disorder   Via 1 gene: ALB 8.59 1
232. Chlorpyrifos Depressive Disorder, Major   Via 1 gene: HTR2A 8.58 1
233. Chlorpyrifos Muscular Dystrophy, Facioscapulohumeral   Via 1 gene: GSTT2 8.56 1
234. Chlorpyrifos Malaria, Falciparum   Via 1 gene: HBB 8.56 1
235. Chlorpyrifos Asbestosis   Via 1 gene: GSTT1 8.54 1
236. Chlorpyrifos Peripheral Nervous System Diseases   Via 1 gene: GFAP 8.46 1
237. Chlorpyrifos Hyperthyroidism   Via 1 gene: PON1 8.38 1
238. Chlorpyrifos Spondylitis, Ankylosing   Via 1 gene: CYP2D6 8.37 1
239. Chlorpyrifos WAGR Syndrome   Via 1 gene: CAT 8.35 1
240. Chlorpyrifos DiGeorge Syndrome   Via 1 gene: COMT 8.32 1
241. Chlorpyrifos beta-Thalassemia   Via 1 gene: HBB 8.28 2
242. Chlorpyrifos Dermatitis, Contact   Via 1 gene: SOD3 8.24 1
243. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Pancreatic Neoplasms   Via 1 gene: CYP2B1 8.22 1
244. Chlorpyrifos Schistosomiasis mansoni   Via 1 gene: SOD1 8.18 1
245. Chlorpyrifos Spinal Dysraphism   Via 1 gene: FGFR2 8.17 1
246. Chlorpyrifos Glomerulonephritis, Membranoproliferative   Via 1 gene: PON1 8.17 1
247. Chlorpyrifos AUTONOMIC CONTROL, CONGENITAL FAILURE OF   Via 1 gene: BDNF 8.15 1
248. Chlorpyrifos Substance Withdrawal Syndrome   Via 1 gene: DRD2 8.10 1
249. Chlorpyrifos Tooth Abnormalities   Via 1 gene: FGFR2 8.06 1
250. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Kidney Neoplasms   Via 1 gene: CYP1A1 8.05 1
251. Chlorpyrifos NASOPHARYNGEAL CARCINOMA, SUSCEPTIBILITY TO, 2   Via 1 gene: TP53 8.02 1
252. Chlorpyrifos ADRENOCORTICAL CARCINOMA, HEREDITARY   Via 1 gene: TP53 8.02 1
253. Chlorpyrifos Hearing Loss   Via 1 gene: COMT 7.99 1
254. Chlorpyrifos Panic Disorder   Via 1 gene: COMT 7.99 1
255. Chlorpyrifos Abnormalities, Multiple   Via 1 gene: FGFR2 7.97 1
256. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate HIV Infections   Via 1 gene: ALB 7.96 1
257. Chlorpyrifos Arteriosclerosis   Via 1 gene: GSTA4 7.94 1
258. Chlorpyrifos Acromegaly   Via 1 gene: IGF1 7.94 1
259. Chlorpyrifos Mental Retardation, X-Linked   Via 1 gene: GRIA3 7.86 1
260. Chlorpyrifos Myocardial Reperfusion Injury   Via 1 gene: ADRB1 7.85 1
261. Chlorpyrifos Epilepsy, Tonic-Clonic   Via 1 gene: CYP2D6 7.72 1
262. Chlorpyrifos Leukemia, Myeloid, Acute   Via 1 gene: MX1 7.70 1
263. Chlorpyrifos Keratosis   Via 1 gene: TP53 7.62 1
264. Chlorpyrifos Demyelinating Diseases   Via 1 gene: TP53 7.62 1
265. Chlorpyrifos Bronchopulmonary Dysplasia   Via 1 gene: IL1B 7.57 1
266. Chlorpyrifos Hyperinsulinism   Via 1 gene: GPX1 7.55 2
267. Chlorpyrifos Atrophy   Via 1 gene: MAPK3 7.47 1
268. Chlorpyrifos Anemia, Sideroblastic   Via 1 gene: SOD2 7.46 1
269. Chlorpyrifos HYPERTENSION, ESSENTIAL   Via 1 gene: CYP3A5 7.38 1
270. Chlorpyrifos Metabolism, Inborn Errors   Via 1 gene: BCHE 7.35 1
271. Chlorpyrifos Limb Deformities, Congenital   Via 1 gene: FGFR2 7.34 1
272. Chlorpyrifos Li-Fraumeni Syndrome   Via 1 gene: TP53 7.34 2
273. Chlorpyrifos Anemia, Hemolytic   Via 1 gene: GPX1 7.28 1
274. Chlorpyrifos Arthritis, Juvenile Rheumatoid   Via 1 gene: IL6 7.28 1
275. Chlorpyrifos Sarcoma, Kaposi   Via 1 gene: IL6 7.28 1
276. Chlorpyrifos Hyperlipoproteinemia Type II   Via 1 gene: PON1 7.27 2
277. Chlorpyrifos Prostatic Intraepithelial Neoplasia   Via 1 gene: ESR1 7.24 1
278. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Lung Neoplasms   Via 1 gene: PON1 7.17 1
279. Chlorpyrifos Pulmonary Emphysema   Via 1 gene: TGFB1 7.15 1
280. Chlorpyrifos Hyperglycemia   Via 1 gene: GPX1 7.14 1
281. Chlorpyrifos Anemia, Iron-Deficiency   Via 1 gene: SOD1 7.14 1
282. Chlorpyrifos Infertility, Male   Via 1 gene: GPX4 7.11 1
283. Chlorpyrifos Hypercholesterolemia   Via 1 gene: PON1 7.08 1
284. Chlorpyrifos Hyperhomocysteinemia   Via 1 gene: PON1 7.08 1
285. Chlorpyrifos Brain Neoplasms   Via 1 gene: PON1 6.98 1
286. Chlorpyrifos Carcinoma, Small Cell   Via 1 gene: TP53 6.95 1
287. Chlorpyrifos Sarcoidosis   Via 1 gene: TGFB1 6.92 1
288. Chlorpyrifos Leiomyoma   Via 1 gene: ESR1 6.91 1
289. Chlorpyrifos Dermatomyositis   Via 1 gene: IL1B 6.90 1
290. Chlorpyrifos HIV Infections   Via 1 gene: HSP90AA1 6.86 1
291. Chlorpyrifos Coronary Disease   Via 1 gene: PON1 6.85 2
292. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Autistic Disorder   Via 1 gene: PON1 6.84 2
293. Chlorpyrifos Carotid Artery Diseases   Via 1 gene: TP53 6.80 1
294. Chlorpyrifos Retinal Degeneration   Via 1 gene: SOD1 6.78 1
295. Chlorpyrifos Burns   Via 1 gene: IL6 6.74 1
296. Chlorpyrifos Kidney Failure, Chronic   Via 1 gene: CAT 6.71 1
297. Chlorpyrifos Inflammation   Via 1 gene: NGF 6.67 1
298. Chlorpyrifos Reperfusion Injury   Via 1 gene: FGF2 6.56 1
299. Chlorpyrifos Nasopharyngeal Neoplasms   Via 1 gene: TP53 6.56 1
300. Chlorpyrifos Cardiomegaly   Via 1 gene: FGF2 6.54 1
301. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Carcinoma, Hepatocellular   Via 1 gene: CYP1A1 6.52 1
302. Chlorpyrifos Diabetic Nephropathies   Via 1 gene: TGFB1 6.51 1
303. Chlorpyrifos Ischemia   Via 1 gene: IL6 6.50 1
304. Chlorpyrifos Multiple Myeloma   Via 1 gene: GSTT1 6.46 1
305. Chlorpyrifos Cholangiocarcinoma   Via 1 gene: IL6 6.40 1
306. Chlorpyrifos Cardiovascular Diseases   Via 1 gene: PON1 6.39 1
307. Chlorpyrifos Craniofacial Abnormalities   Via 1 gene: FGFR2 6.27 3
308. Chlorpyrifos Duodenal Ulcer   Via 1 gene: TGFB1 6.24 1
309. Chlorpyrifos Fibrosis   Via 1 gene: TGFB1 6.12 2
310. Chlorpyrifos Arthritis, Experimental   Via 1 gene: ABCB1 6.09 1
311. Chlorpyrifos Sarcoma   Via 1 gene: TP53 6.04 1
312. Chlorpyrifos Lung Diseases   Via 1 gene: TGFB1 6.01 1
313. Chlorpyrifos Cystic Fibrosis   Via 1 gene: TGFB1 5.98 1
314. Chlorpyrifos Hemangiosarcoma   Via 1 gene: TP53 5.93 1
315. Chlorpyrifos Mammary Neoplasms, Experimental   Via 1 gene: IGF1 5.86 3
316. Chlorpyrifos Crohn Disease   Via 1 gene: IL6 5.82 1
317. Chlorpyrifos Carcinoma, Basal Cell   Via 1 gene: TP53 5.80 1
318. Chlorpyrifos Respiratory Hypersensitivity   Via 1 gene: IL6 5.74 1
319. O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate Breast Neoplasms   Via 1 gene: CYP1A1 5.72 1
320. Chlorpyrifos Kidney Neoplasms   Via 1 gene: CYP1A1 5.62 1
321. Chlorpyrifos Kidney Diseases   Via 1 gene: TGFB1 5.52 1
322. Chlorpyrifos Skin Neoplasms   Via 1 gene: TGFB1 5.35 1
323. Chlorpyrifos Thyroid Neoplasms   Via 1 gene: TP53 5.31 1
324. Chlorpyrifos Carcinoma, Renal Cell   Via 1 gene: TP53 5.29 1
325. Chlorpyrifos Colitis, Ulcerative   Via 1 gene: IL1B 5.26 1
326. Chlorpyrifos Myocardial Infarction   Via 1 gene: ESR1 5.22 2
327. Chlorpyrifos Glioma   Via 1 gene: TP53 5.18 1
328. Chlorpyrifos Carcinoma, Non-Small-Cell Lung   Via 1 gene: TP53 5.05 1
329. Chlorpyrifos Lupus Erythematosus, Systemic   Via 1 gene: IL6 5.00 1
330. Chlorpyrifos Neoplasms   Via 1 gene: CYP1A2 4.87 1
331. Chlorpyrifos Melanoma   Via 1 gene: TP53 4.75 1
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