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ChemicalChemical: Sulfur Compounds

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The following diseases are associated with Sulfur Compounds or at least one of its descendants. Each association is direct (M marker/mechanism and/or T therapeutic) and/or inferred (via a curated gene interaction).

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  Chemical Disease Direct Evidence Inference Network Inference Score References
1. Chlorpyrifos Respiratory Sounds M   3
2. Chlorpyrifos Sex Chromosome Aberrations M   1
3. Chlorpyrifos Neurotoxicity Syndromes M   1
4. Disulfiram Abnormalities, Drug-Induced M   1
5. Glyburide Hypoglycemia M   1
6. Glyburide Neurotoxicity Syndromes M   1
7. ethylenebis(isothiocyanate) Fetal Death M   1
8. ethylenebis(isothiocyanate) Pregnancy Complications M   1
9. Furosemide Hyperparathyroidism, Secondary M   1
10. Furosemide Nephrocalcinosis M   1
11. Furosemide Hypotension, Orthostatic M   1
12. Furosemide Hypercalciuria M   1
13. diethylthiourea Thyroid Neoplasms M   2
14. ferbam Infertility M   1
15. Piroxicam Liver Diseases M   1
16. Piroxicam Urticaria M   1
17. perfluorooctane sulfonic acid Glioblastoma M   1
18. Phorate Agricultural Workers' Diseases M   2
19. Phorate Respiratory Tract Diseases M   2
20. Phorate Respiratory Sounds M   2
21. Parathion Respiratory Tract Diseases M   1
22. Parathion Respiratory Sounds M   2
23. zafirlukast Vasculitis M   1
24. zafirlukast Pancreatitis M   1
25. zafirlukast Necrosis M   1
26. zafirlukast Nausea M   1
27. zafirlukast Hepatitis M   1
28. zafirlukast Headache M   2
29. zafirlukast Leukocytosis M   1
30. zafirlukast Pharyngitis M   2
31. C.I. Acid Red 114 Liver Neoplasms M   1
32. C.I. Acid Red 114 Colonic Neoplasms M   1
33. C.I. Acid Red 114 Intestinal Neoplasms M   1
34. C.I. Acid Red 114 Adrenal Gland Neoplasms M   1
35. C.I. Acid Red 114 Adenocarcinoma M   1
36. C.I. Acid Red 114 Breast Neoplasms M   2
37. C.I. Acid Red 114 Mouth Neoplasms M   1
38. C.I. Acid Red 114 Leukemia M   1
39. C.I. Acid Red 114 Skin Neoplasms M   1
40. C.I. Acid Red 114 Pheochromocytoma M   1
41. C.I. Acid Red 114 Coronary Thrombosis M   1
42. dimethyl sulfide Cystic Fibrosis M   1
43. cysteinyl-leukotriene Asthma M   1
44. chlorimuron ethyl Agricultural Workers' Diseases M   1
45. chlorimuron ethyl Respiratory Tract Diseases M   1
46. chlorimuron ethyl Respiratory Sounds M   1
47. CDEC Breast Neoplasms M   1
48. Diazinon Urologic Diseases M   1
49. Diazinon Dyspnea M   1
50. Diazinon Hepatitis M   1
51. ziprasidone Tachycardia, Ventricular M   1
52. Dapsone Liver Diseases M   1
53. Dapsone Hemosiderosis M   1
54. 1-Naphthylisothiocyanate Peliosis Hepatis M   1
55. 1-Naphthylisothiocyanate Cholestasis, Intrahepatic M   2
56. 1-Naphthylisothiocyanate Cholangitis M   1
57. nabam Dermatitis, Allergic Contact M   1
58. nabam Dermatitis, Occupational M   1
59. nabam Agricultural Workers' Diseases M   1
60. Endosulfan Emphysema M   1
61. Endosulfan Dyspnea M   2
62. Endosulfan Hemorrhage M   1
63. Endosulfan Learning Disorders M   1
64. Endosulfan Cyanosis M   1
65. Endosulfan Seizures M   2
66. 2-amino-5-nitrothiazole Pituitary Neoplasms M   1
67. 2-amino-5-nitrothiazole Leukemia, Myeloid M   1
68. Fonofos Agricultural Workers' Diseases M   1
69. Fonofos Respiratory Tract Diseases M   1
70. Fonofos Respiratory Sounds M   1
71. Chlorpyrifos Respiratory Tract Diseases M   2
72. Maneb Abnormalities, Drug-Induced M   1
73. Maneb Gliosis M   1
74. Malathion Agricultural Workers' Diseases M   2
75. Malathion Respiratory Tract Diseases M   1
76. Malathion Respiratory Sounds M   2
77. pirimiphos methyl Infertility, Male M   1
78. Thiram Erythema Multiforme M   1
79. Thiram Infertility M   1
80. Thiourea Pulmonary Edema M   1
81. Thioridazine Death, Sudden, Cardiac M   1
82. Thioridazine Tachycardia, Ventricular M   1
83. Thioglycolates Peritonitis M   6
84. Thioacetamide Fat Necrosis M   1
85. Thioacetamide Hepatic Encephalopathy M   2
86. phenothiazine Long QT Syndrome M   1
87. Sulfonamides Liver Diseases M   1
88. tenoxicam Liver Diseases M   1
89. Trinitrobenzenesulfonic Acid Fibrosis M   1
90. Trinitrobenzenesulfonic Acid Colitis M   9
91. Carbon Disulfide Nervous System Diseases M   1
92. Carbon Disulfide Parkinsonian Disorders M   1
93. Carbon Disulfide Neurotoxicity Syndromes M   1
94. Busulfan Hepatic Veno-Occlusive Disease M   1
95. S-(1,2,2-trichlorovinyl)-L-cysteine Kidney Diseases M   1
96. Methomyl Pancreatitis M   2
97. Methomyl Seizures M   2
98. Methionine Child Development Disorders, Pervasive M   1
99. 1-Naphthylisothiocyanate Thrombocytopenia M   1
100. Ziram Infertility M   1
101. Zineb Dermatitis, Allergic Contact M   1
102. Zineb Dermatitis, Occupational M   1
103. Zineb Agricultural Workers' Diseases M   1
104. zafirlukast Churg-Strauss Syndrome M   1
105. terbufos Respiratory Tract Diseases M   1
106. terbufos Respiratory Sounds M   1
107. propineb Dermatitis, Allergic Contact M   1
108. propineb Dermatitis, Occupational M   1
109. propineb Agricultural Workers' Diseases M   1
110. EPTC Pancreatic Neoplasms M   1
111. EPTC Agricultural Workers' Diseases M   1
112. EPTC Respiratory Sounds M   1
113. mancozeb Dermatitis, Occupational M   1
114. mancozeb Agricultural Workers' Diseases M   3
115. mancozeb Neural Tube Defects M   1
116. mancozeb Nerve Degeneration M   1
117. mancozeb Abnormalities, Drug-Induced M   1
118. mancozeb Leukemia, Lymphoid M   1
119. mancozeb Skin Neoplasms M   1
120. Hydrochlorothiazide Hypotension, Orthostatic M   1
121. Homocysteine Glaucoma M   1
122. Homocysteine Exfoliation Syndrome M   1
123. nimesulide Urticaria M   1
124. terbufos Agricultural Workers' Diseases M   1
125. Azathioprine Pancreatitis M   1
126. rofecoxib Intestinal Diseases M   1
127. polymarcine Dermatitis, Allergic Contact M   1
128. polymarcine Dermatitis, Occupational M   1
129. polymarcine Agricultural Workers' Diseases M   1
130. zinc ammonium sulfate Acidosis M   1
131. zinc ammonium sulfate Hypotension M   1
132. zinc ammonium sulfate Anoxia M   1
133. Amoxicillin-Potassium Clavulanate Combination Liver Diseases M   1
134. Copper Sulfate Hypertension, Pulmonary M   1
135. Copper Sulfate Acidosis, Respiratory M   1
136. Copper Sulfate Anoxia M   1
137. Zinc Sulfate Acidosis M   1
138. Zinc Sulfate Hypotension M   1
139. Zinc Sulfate Anoxia M   1
140. methamidophos Muscle Weakness M   1
141. methamidophos Infertility, Male M   1
142. methamidophos Autonomic Nervous System Diseases M   1
143. methamidophos Polyneuropathies M   1
144. methamidophos Foodborne Diseases M   1
145. Maneb Dermatitis, Allergic Contact M   1
146. Maneb Dermatitis, Occupational M   1
147. Maneb Agricultural Workers' Diseases M   1
148. Maneb Nerve Degeneration M   2
149. Thioacetamide Liver Cirrhosis, Experimental M Via 58 genes: ABCB1; ABCB1A; ADH4; ADIPOQ; ADORA2A; AFP; AGT; AGTR1A; ALDH1A1; ALDH2; CCL2; CDO1; CES2; CYGB; CYP3A11; FMO1; GH1; GHR; GOT1; GPT; GSTM1; GULO; HAO2; HGF; HMOX1; HPSE; ID2; IGF1; IGFBP1; IGFBP2; IL10; IL1B; INHBE; ITGB6; KRT18; KRT8; LEP; MMP1; MMP13; MMP2; MMP8; MMP9; NOS2; NT5E; OBP3; PCK1; PDGFRB; PLG; POMC; PTGS2; RNASE4; SMAD2; SULT1E1; TGFB1; TGFBR2; TIMP1; TNF; VEGFA 427.38 88
150. Thioacetamide Liver Diseases M Via 33 genes: AFP; ALOX5AP; ALPL; BCL2L1; CCL2; CCR1; CD79B; CD86; CRISPLD2; DDAH1; ENO3; GGT1; GRK5; HK3; HMOX1; HSPA1A; IL1R2; IL1RAP; ITGB6; JUP; LTB4R; MMP9; NOS2; NQO1; NRP1; OBP3; RNASE6; RT1-DOA; SERPINA1; SOCS3; SOD1; ST8SIA1; TGM1 263.75 16
151. Thioacetamide Carcinoma, Hepatocellular M Via 18 genes: ACTB; ADD1; AFP; APCS; BCL2L1; CASP8; CYP1A1; DPYD; GJB1; GSTP1; IL6; MYC; PCK1; PTGS2; PYGL; RB1; TGFB1; TP53 113.26 16
152. Malathion Neurotoxicity Syndromes M Via 9 genes: ADD3; CCK; CRISPLD2; LAT; P2RX1; RNASE6; SFRS5; ST8SIA1; TIMP3 103.13 2
153. Thioridazine Lipidoses M Via 9 genes: C10ORF10; FABP1; FNDC4; HPN; LSS; SERPINA3; SLC2A3; TAGLN; WIPI1 101.32 3
154. Chlorpromazine Lipidoses M Via 9 genes: C10ORF10; FABP1; FNDC4; GDPD3; HPN; LSS; SERPINA3; SLC2A3; WIPI1 98.85 3
155. Thioacetamide Drug-Induced Liver Injury M Via 15 genes: APOH; BAX; CXCL10; CYP2E1; ENO1; GCLC; GSTT1; HMOX1; IL1B; IL1R2; IL6; MAP3K5; MMP2; PTGS2; PZP 96.50 14
156. Methyl Parathion Neurotoxicity Syndromes M Via 7 genes: ADD3; CCK; GABRR2; P2RX1; SFRS5; TGM1; TIMP3 78.56 1
157. 1-Naphthylisothiocyanate Drug-Induced Liver Injury M Via 9 genes: BAX; CXCL1; CYP2E1; GSTT1; HMOX1; IFNG; IL1B; IL6; TTR 58.25 13
158. Methionine Autistic Disorder M Via 7 genes: GAD1; IFNG; IGF1; MIF; NOS2; RELN; SHANK3 56.44 11
159. Malathion Breast Neoplasms M Via 8 genes: CENPF; CYP3A4; HRAS; HRAS1; IFNB1; IFNG; TP53; TYMS 56.30 14
160. 1-Naphthylisothiocyanate Liver Diseases M Via 8 genes: CYP1A2; GGT1; HMOX1; HSPA1A; NOS2; NQO1; SOCS3; TXN 54.11 9
161. selenomethylselenocysteine Breast Neoplasms M Via 8 genes: BCL2; CCND1; CDKN1B; ESR1; GPX1; GPX4; JUN; MKI67 52.10 11
162. Maneb Parkinson Disease M Via 5 genes: CYP2E1; GPX1; GSTA4; SLC6A3; SOD1 44.02 6
163. Homocysteine Autistic Disorder M Via 6 genes: BCL2; CAT; COMT; GPX1; MECP2; MTHFR 41.10 8
164. Homocysteine Coronary Artery Disease M Via 4 genes: CCL2; GPX1; NOS3; VEGFA 35.55 5
165. Thiram Osteochondrodysplasias M Via 3 genes: BCL2; FLT1; KDR 30.74 3
166. Homocysteine Schizophrenia M Via 4 genes: CCL2; COMT; MTHFR; TP53 30.51 6
167. troglitazone Drug-Induced Liver Injury M Via 4 genes: GSTT1; IL1B; IL6; PTGS2 25.49 5
168. Parathion Breast Neoplasms M Via 4 genes: CYP3A4; HRAS; HRAS1; TP53 25.09 9
169. Ditiocarb Parkinson Disease M Via 3 genes: CYP2E1; SNCA; SOD1 24.47 12
170. Trinitrobenzenesulfonic Acid Colitis, Ulcerative M Via 4 genes: IL10; IL12B; IL1B; RELA 24.43 5
171. Thioacetamide Liver Failure, Acute M Via 3 genes: HGF; MAPK8; POMC 22.18 5
172. Trinitrobenzenesulfonic Acid Inflammatory Bowel Diseases M Via 3 genes: ABCB1; DEFA5; IL6 21.54 4
173. Methimazole Hypothyroidism M Via 2 genes: TG; TSHB 20.53 2
174. Homocysteine Hyperhomocysteinemia M Via 2 genes: MTHFR; MTRR 20.31 7
175. Thioacetamide Cholangiocarcinoma M Via 3 genes: IL6; NOS2; PTGS2 18.77 3
176. S-Adenosylhomocysteine Autistic Disorder M Via 2 genes: COMT; SLC19A1 17.28 1
177. Chlorpyrifos Liver Diseases M Via 3 genes: ALPL; CYP1A2; SOD1 17.07 4
178. Trinitrobenzenesulfonic Acid Pancreatitis M Via 2 genes: PRSS1; TRPV1 16.96 2
179. Homocysteine Heart Defects, Congenital M Via 2 genes: EDN1; MTHFR 16.81 3
180. Homocysteine Parkinson Disease M Via 2 genes: GPX1; SOD1 14.55 2
181. S-Adenosylmethionine Autistic Disorder M Via 2 genes: COMT; SLC19A1 14.04 2
182. Diazinon Poisoning M Via 2 genes: ACHE; PON1 13.68 3
183. Ritonavir Drug-Induced Liver Injury M Via 2 genes: ALB; IL6 13.29 3
184. Thioglycolates Acute-Phase Reaction M Via 1 gene: ANG 12.58 1
185. Cysteine Autistic Disorder M Via 2 genes: GSTM1; GSTP1 12.55 5
186. zafirlukast Drug-Induced Liver Injury M Via 2 genes: IFNG; IL6 12.19 4
187. Floxacillin Drug-Induced Liver Injury M Via 1 gene: HLA-B 11.63 1
188. Carbon Disulfide Atherosclerosis M Via 1 gene: LPA 11.44 3
189. methamidophos Peripheral Nervous System Diseases M Via 1 gene: NEFH 11.43 3
190. methamidophos Nervous System Diseases M Via 1 gene: PNPLA6 11.35 3
191. 4-iodine-benzo(b)thiophene-2-carboxamidine Neoplasm Recurrence, Local M Via 1 gene: PLAU 10.70 1
192. 1-Naphthylisothiocyanate Cholestasis M Via 1 gene: OSTB 10.69 8
193. Homocysteine Meningomyelocele M Via 1 gene: MTHFR 10.49 1
194. dinitrobenzenesulfonic acid Colitis M Via 1 gene: ALOX5 10.27 3
195. Disulfiram Neurotoxicity Syndromes M Via 1 gene: CCK 9.67 2
196. Thioridazine Long QT Syndrome M Via 1 gene: KCNH2 8.80 6
197. Methomyl Poisoning M Via 1 gene: ACHE 8.77 2
198. methamidophos Poisoning M Via 1 gene: ACHE 8.73 3
199. Ritonavir Neutropenia M Via 1 gene: UGT1A1 8.67 2
200. Ethionine Blood Coagulation Disorders M Via 1 gene: CFI 8.64 2
201. Omeprazole Blood Coagulation Disorders M Via 1 gene: CFI 8.57 2
202. Disulfiram Limb Deformities, Congenital M Via 1 gene: TGFB2 8.55 2
203. 4-iodine-benzo(b)thiophene-2-carboxamidine Prostatic Neoplasms M Via 1 gene: PLAU 8.34 3
204. diethylthiourea Liver Neoplasms M Via 1 gene: CYP2E1 8.21 2
205. Thioacetamide Blood Coagulation Disorders M Via 1 gene: CFI 8.18 2
206. S-methylisothiopseudouronium Myocardial Infarction M Via 1 gene: NOS2 8.00 2
207. Methyl Parathion Poisoning M Via 1 gene: ACHE 7.90 2
208. Parathion Agricultural Workers' Diseases M Via 1 gene: PON1 7.82 3
209. mancozeb Dermatitis, Allergic Contact M Via 1 gene: IFNG 7.78 2
210. Diazinon Infertility, Male M Via 1 gene: GPX4 7.09 3
211. Homocysteine Myocardial Infarction M Via 1 gene: NOS3 6.98 2
212. Parathion Infertility, Male M Via 1 gene: AR 6.73 3
213. 1-Naphthylisothiocyanate Hepatitis M Via 1 gene: HMOX1 6.56 2
214. Chlorpyrifos Agricultural Workers' Diseases M Via 1 gene: PON1 6.50 4
215. Diazinon Agricultural Workers' Diseases M Via 1 gene: PON1 6.49 2
216. Endosulfan Infertility, Male M Via 1 gene: AR 6.36 4
217. nimesulide Liver Diseases M Via 1 gene: NOS2 6.32 2
218. mancozeb Pancreatic Neoplasms M Via 1 gene: TNF 6.24 3
219. Trinitrobenzenesulfonic Acid Intestinal Diseases M Via 1 gene: NOS2 5.99 2
220. Chlorpromazine Liver Diseases M Via 1 gene: CYP1A2 5.88 2
221. Thioacetamide Hepatitis M Via 1 gene: HMOX1 5.57 2
222. zafirlukast Sinusitis M T   2
223. zafirlukast Eosinophilia M T   5
224. erdosteine Drug-Induced Liver Injury T   1
225. 2,5-dimethylcelecoxib Multiple Myeloma T   1
226. Sumatriptan Nausea T   1
227. Sumatriptan Hyperacusis T   1
228. Sumatriptan Photophobia T   1
229. Sumatriptan Headache T   1
230. clazosentan Subarachnoid Hemorrhage T   1
231. Pyrantel Pamoate Horse Diseases T   1
232. Pyrantel Pamoate Nematode Infections T   1
233. rosiglitazone Fatty Liver T   1
234. rosiglitazone Edema T   1
235. meloxicam Neoplasms T   1
236. meloxicam Vomiting T   1
237. 6,8-dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo(2,3-f)xanthine Cholestasis T   1
238. Promethazine Hypersensitivity T   1
239. Promethazine Hyperalgesia T   1
240. Promethazine Edema T   1
241. Promethazine Motion Sickness T   1
242. Silver Sulfadiazine Burns T   1
243. Ralitoline Epilepsy, Tonic-Clonic T   1
244. Ampicillin Sinusitis T   1
245. Amoxicillin Helicobacter Infections T   1
246. Sulfasalazine Inflammatory Bowel Diseases T   1
247. Sulfasalazine Behcet Syndrome T   1
248. (1'S, 2S)-4-amino-N-(1'-carbamoyl-2'-phenylethyl)-2-(4''-methyl-1''-naphthalenesulfonylamino)butanamide Edema T   1
249. 2-ethyloestradiol-bis-sulfamate Neoplasms T   1
250. Acetazolamide Seizures T   1
251. 3-aminopyridine-2-carboxaldehyde thiosemicarbazone Neoplasms T   1
252. flupenthixol decanoate Dementia T   1
253. KW 2581 Mammary Neoplasms, Experimental T   1
254. netoglitazone Multiple Myeloma T   1
255. disufenton sodium Stroke T   1
256. Azlocillin Infection T   1
257. Azathioprine Behcet Syndrome T   1
258. rofecoxib Pain, Postoperative T   1
259. rofecoxib Endometriosis T   1
260. XCT790 Liver Neoplasms T   1
261. (((4-nitrophenyl)amino)(2,2,4,4-tetramethyl thiochroman-6-yl)amino) methane-1-thione Ovarian Neoplasms T   1
262. tazobactam Peritonitis T   1
263. ibutilide Arrhythmias, Cardiac T   2
264. clopidogrel Retinal Vein Occlusion T   1
265. clopidogrel Acute Coronary Syndrome T   1
266. ABT-737 Small Cell Lung Carcinoma T   1
267. MAID protocol Liposarcoma T   1
268. MAID protocol Sarcoma T   2
269. MAID protocol Soft Tissue Neoplasms T   1
270. Amoxicillin-Potassium Clavulanate Combination Neisseriaceae Infections T   1
271. Levamisole Cattle Diseases T   1
272. Levamisole Strongyloidiasis T   1
273. etoricoxib Alveolar Bone Loss T   1
274. etoricoxib Periodontitis T   1
275. Ketotifen Hypersensitivity T   1
276. Ketotifen Rhinitis, Allergic, Perennial T   1
277. Ritonavir Leukemia-Lymphoma, Adult T-Cell T   1
278. LY 117018 Osteoporosis, Postmenopausal T   2
279. LY 117018 Arthritis, Rheumatoid T   1
280. Zinc Sulfate Hepatolenticular Degeneration T   1
281. fasudil Liver Cirrhosis, Experimental T   1
282. fasudil Vasospasm, Intracranial T   1
283. thiamine disulfide Acquired Immunodeficiency Syndrome T   1
284. 3-(4-methylphenylsulfonyl)-2-propenenitrile Lymphoma, T-Cell T   1
285. allyl sulfide Hepatitis, Viral, Human T   1
286. Thioctic Acid Retinitis Pigmentosa T   1
287. torsemide Ventricular Dysfunction, Left T   1
288. torsemide Heart Failure T   1
289. Ticlopidine Thrombosis T   1
290. Thioridazine Malaria, Falciparum T   1
291. Thioridazine Psychotic Disorders T   1
292. Thioridazine Dementia T   1
293. Thioridazine Mental Disorders T   1
294. Thiamine Child Nutrition Disorders T   1
295. Thiabendazole Horse Diseases T   1
296. Thiabendazole Nematode Infections T   1
297. Sucralfate Stomach Ulcer T   2
298. Aztreonam Cystic Fibrosis T   1
299. Azlocillin Malaria, Falciparum T   1
300. ciglitazone Encephalomyelitis, Autoimmune, Experimental T   1
301. fomivirsen Cytomegalovirus Retinitis T   2
302. pyrrolidine dithiocarbamic acid Influenza, Human T   1
303. Chlorprothixene Malaria, Falciparum T   1
304. Chlorprothixene Psychotic Disorders T   2
305. Chlorprothixene Herpes Simplex T   1
306. Chlorprothixene Mycoplasma Infections T   1
307. Chlorprothixene Mental Disorders T   1
308. Chlorpropamide Glucose Metabolism Disorders T   1
309. Chlorpromazine Herpes Simplex T   1
310. Chlorpromazine Mycoplasma Infections T   1
311. Chlorpromazine Mental Disorders T   1
312. Chlormethiazole Liver Diseases, Alcoholic T   1
313. celecoxib Endometriosis T   1
314. celecoxib Mammary Neoplasms, Experimental T   1
315. N-((2'-(((4,5-dimethyl-3-isoxazolyl)amino)sulfonyl)-4-(2-oxazolyl)(1,1'-biphenyl)-2-yl)methyl)-N,3,3-trimethylbutanamide Heart Failure T   1
316. Methylene Blue Priapism T   1
317. Methotrimeprazine Mental Disorders T   1
318. Methazolamide Cardiomegaly T   1
319. Clopenthixol Mycoplasma Infections T   1
320. Clopenthixol Mental Disorders T   1
321. metacept-1 Leukemia T   1
322. rivaroxaban Embolism and Thrombosis T   1
323. 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone Adenocarcinoma T   1
324. 5-((4-methylphenyl)methylene)-2-(phenylamino)-4(5H)-thiazolone Carcinoma, Non-Small-Cell Lung T   1
325. sitaxsentan Hypertension, Pulmonary T   1
326. sitaxsentan Cardiovascular Diseases T   1
327. 2-ethylestradiol sulfamate Breast Neoplasms T   2
328. 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)-2-((2-methylamino)carbonyl)hydrazine ACUTE MYELOGENOUS LEUKEMIA T   1
329. zafirlukast Pulmonary Disease, Chronic Obstructive T   2
330. zafirlukast Conjunctivitis, Allergic T   1
331. zafirlukast Urticaria T   2
332. zafirlukast Hypertension, Pulmonary T   1
333. zafirlukast Endometriosis T   1
334. zafirlukast Rhinitis T   3
335. zafirlukast Bronchial Diseases T   1
336. zafirlukast Pulmonary Edema T   1
337. zafirlukast Edema T   1
338. zafirlukast Nasal Polyps T   2
339. zafirlukast Candidiasis, Vulvovaginal T   1
340. zafirlukast Dermatitis, Atopic T   1
341. zafirlukast Decompression Sickness T   1
342. zafirlukast Cystic Fibrosis T   1
343. zafirlukast Asthma, Aspirin-Induced T   1
344. zafirlukast Asthma, Exercise-Induced T   5
345. zafirlukast ALLERGIC RHINITIS T   1
346. zafirlukast Cough T   1
347. zafirlukast Lung Diseases, Obstructive T   1
348. Omeprazole Duodenal Ulcer T   2
349. Omeprazole Stomach Ulcer T   5
350. Omeprazole Stomach Diseases T   1
351. STX64 compound Endometrial Neoplasms T   1
352. bosentan Coxsackievirus Infections T   1
353. YH 439 Skin Neoplasms T   1
354. Thiazolidinediones Endometriosis T   1
355. Thiazolidinediones Peritonitis T   1
356. ebrotidine Stomach Ulcer T   1
357. ramatroban Conjunctivitis, Allergic T   1
358. ramatroban Eosinophilia T   2
359. ramatroban Edema T   1
360. ramatroban ALLERGIC RHINITIS T   2
361. sulforafan Autoimmune Diseases T   1
362. Diazoxide Hypertension, Pregnancy-Induced T   1
363. Diazoxide Parkinsonian Disorders T   2
364. Diazoxide HYPOGLYCEMIA, LEUCINE-INDUCED T   1
365. ziprasidone Mental Disorders T   1
366. ziprasidone Autistic Disorder T   1
367. Famotidine Duodenal Ulcer T   1
368. Famotidine Stomach Ulcer T   2
369. Cysteamine Acquired Immunodeficiency Syndrome T   1
370. troglitazone Leukemia, Erythroblastic, Acute T   1
371. troglitazone Diabetic Angiopathies T   1
372. quetiapine Mental Disorders T   1
373. 5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin Carcinoma, Non-Small-Cell Lung T   1
374. vardenafil Erectile Dysfunction T   1
375. vardenafil Urinary Bladder Neck Obstruction T   1
376. strontium ranelate Osteoporosis T   1
377. Amifostine Stomach Diseases T   1
378. 2-(2-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-4-(trifluoromethyl)phenoxy)-4,5-dichlorobenzenesulfonic acid Inflammation T   1
379. N-((4-(5,9-diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo(3,4-g)quinolin-7-yl)-3-methylbenzyl)sulfonyl)-2-(2-methoxyphenyl)acetamide Osteoarthritis T   1
380. lansoprazole Enteritis T   1
381. lansoprazole Duodenal Ulcer T   1
382. lansoprazole Stomach Ulcer T   5
383. Disulfiram Osteosarcoma T   1
384. Disulfiram Acquired Immunodeficiency Syndrome T   1
385. Disulfiram Neovascularization, Pathologic T   1
386. Disulfiram Neoplasms T   1
387. Disulfiram Neoplasm Invasiveness T   1
388. Disulfiram Candidiasis T   1
389. Disulfiram Cocaine-Related Disorders T   1
390. phenethyl isothiocyanate Testicular Diseases T   1
391. Succimer Autistic Disorder T   1
392. zotepine Mental Disorders T   1
393. N'-((2-hydroxyphenyl)carbonothioyl)pyridine-2-carbohydrazide Neoplasms T   1
394. 4-(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-1,3-thiazol-2-yl)benzoic acid Acne Vulgaris T   1
395. oblimersen Lymphoma, B-Cell T   1
396. oblimersen Multiple Myeloma T   1
397. oblimersen Melanoma T   2
398. oblimersen Leukemia, Lymphocytic, Chronic, B-Cell T   1
399. alliin Neovascularization, Pathologic T   1
400. Glipizide Diabetes Mellitus T   1
401. Furosemide Nocturnal Enuresis T   1
402. Furosemide Edema T   1
403. Furosemide Dyspnea T   1
404. Furosemide Hypoproteinemia T   1
405. Furosemide Polyuria T   1
406. Fluphenazine Mental Disorders T   1
407. Flupenthixol Herpes Simplex T   1
408. Flupenthixol Mental Disorders T   1
409. Piroxicam Intestinal Neoplasms T   1
410. Piperacillin Peritonitis T   1
411. Perphenazine Mental Disorders T   1
412. Perazine Psychotic Disorders T   1
413. Perazine Mental Disorders T   1
414. E 6080 Edema T   1
415. N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide Hypertension, Pulmonary T   1
416. N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide Cardiovascular Diseases T   1
417. pantoprazole Helicobacter Infections T   1
418. imidazolium-bis(imidazole)dimethylsulfoxideimidazotetrachlororuthenate(III) Neoplasms T   1
419. sildenafil Stomach Diseases T   1
420. 2-oxothiazolidine-4-carboxylic acid Melanoma, Experimental T   1
421. (2,8-dioxabicyclo(3.3.0)oct-6-yl)-N-(4-((3,4-methylenedioxyphenyl)sulfonyl-(2-methylpropyl)amino)-3-hydroxy-1-phenylbutan-2-yl) carbamate HIV Infections T   1
422. bicalutamide Prostatic Neoplasms T Via 45 genes: ADAM9; ADRB2; AGR2; AKT1; AMACR; AR; ATF3; BAX; BCL2; BNIP3; CD9; CDH1; CDKN1A; CDKN1B; CLU; CREBBP; EGF; EZR; GADD45A; GREB1; ICAM1; IGF1; IGFBP3; IL6; KLK2; KLK3; MBD2; MME; MMP13; MYC; NCOA1; NCOA2; NKX3-1; NRP1; PTEN; PTGS2; SERPINE1; TERT; TLR4; TMSB4X; TP53; TPD52; TYMS; UGT2B17; UXT 336.93 61
423. celecoxib Prostatic Neoplasms T Via 20 genes: AKT1; AR; CAV1; CCND1; CDKN1A; CDKN1B; CRYAB; CYP19A1; EGFR; GDF15; GSTP1; IL6; MMP9; NGFR; NR3C1; PARP1; PTGS2; SOD2; TP53; VEGFA 131.60 43
424. pioglitazone Liver Cirrhosis, Experimental T Via 14 genes: ADIPOQ; CYP17A1; GOT1; GPT; GSTA2; IFNG; IL1B; MMP13; MMP9; NOS2; PTGS2; TGFB1; TIMP1; TNF 103.19 19
425. pyrrolidine dithiocarbamic acid Prostatic Neoplasms T Via 15 genes: AR; BCL2; CASP9; EGF; ICAM1; IL18; IL2; IL6; IL8; KLK3; MMP9; NGFR; PLAU; PTGS2; TP53 98.13 35
426. Furosemide Stomach Neoplasms T Via 11 genes: BID; BIRC2; BIRC5; CASP8; GADD45A; ITGA5; NOS3; PTGS2; TGFA; TNF; TNFSF9 73.30 11
427. Methionine Liver Cirrhosis, Experimental T Via 9 genes: CYGB; IFNG; IGF1; NOS2; PDGFRB; TGFB1; TGFBR2; TIMP1; TNF 70.49 19
428. Furosemide Reperfusion Injury T Via 8 genes: EFNA5; FGF2; ID3; IL10; ITGA5; KDR; THBS1; TNF 68.37 2
429. celecoxib Stomach Neoplasms T Via 10 genes: BIRC5; CA2; CAV1; CDKN1A; CDKN1B; EGFR; IL1B; PTGS2; SOD2; TNF 67.78 12
430. Cysteine Liver Cirrhosis, Experimental T Via 8 genes: CYGB; GSTA2; GSTM1; HMOX1; PDGFRB; TGFB1; TGFBR2; TIMP1 65.06 16
431. Acetylcysteine Drug-Induced Liver Injury T Via 10 genes: ALB; BAX; CXCL1; GCLC; HMOX1; IL1B; IL6; MAP3K5; MMP2; PTGS2 64.94 10
432. rosiglitazone Liver Cirrhosis, Experimental T Via 11 genes: ADIPOQ; CYP17A1; GSTA2; IL10; IL1B; LEP; NOS2; PCK1; PTGS2; TGFB1; TNF 64.90 20
433. Acetylcysteine Carcinoma, Squamous Cell T Via 9 genes: ALDH2; CDKN1A; HIF1A; IL8; MMP9; NFE2L2; PTGS2; STAT3; VEGFA 60.50 9
434. 1,3-dimethylthiourea Liver Cirrhosis, Experimental T Via 8 genes: CCL2; EDN1; GCK; GSTA2; HMOX1; HPSE; IL1B; TNF 59.06 9
435. pyrrolidine dithiocarbamic acid Liver Cirrhosis, Experimental T Via 9 genes: AGT; CCL2; HMOX1; IFNG; IL1B; MMP9; NOS2; PTGS2; TNF 56.80 13
436. Taurine Liver Cirrhosis, Experimental T Via 8 genes: ADORA2A; AGT; GPT; HMOX1; IL1B; TGFB1; TNF; VEGFA 53.05 13
437. Disulfiram Prostatic Neoplasms T Via 9 genes: AR; BAX; CDKN1B; CYP2E1; MMP9; MT2A; NQO1; PARP1; PTGS2 51.29 23
438. celecoxib Colonic Neoplasms T Via 7 genes: ALOX5; BIRC5; CCND1; IL1B; MMP9; TP53; VEGFA 47.39 8
439. Thiram Prostatic Neoplasms T Via 7 genes: BCL2; CYP2E1; MMP13; MMP9; NR3C1; SOD2; VEGFA 46.32 11
440. celecoxib Colorectal Neoplasms T Via 7 genes: AKT1; BIRC5; CCND1; EGFR; PPARG; PTGS2; TP53 45.80 15
441. diallyl disulfide Prostatic Neoplasms T Via 6 genes: ATF3; BCL2; CYP1A1; CYP2E1; GDF15; TP53 44.61 9
442. Acetylcysteine Neoplasm Metastasis T Via 6 genes: DAPK1; EGFR; MMP2; MMP9; PLAU; TP53 43.98 6
443. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide Melanoma T Via 6 genes: CASP8; FASLG; GDF15; PTGS2; TNF; TP53 42.66 6
444. rosiglitazone Alzheimer Disease T Via 7 genes: APP; BAX; BCL2; IL1B; NOS3; PPARG; TNF 41.73 17
445. Disulfiram Breast Neoplasms T Via 7 genes: CASP7; CDKN1B; NFKBIA; NOS2; NQO1; PTGS2; TNF 40.52 10
446. S-allylcysteine Prostatic Neoplasms T Via 5 genes: BCL2; CDH1; JUP; KLK3; TGFB1 38.90 12
447. pioglitazone Autistic Disorder T Via 6 genes: IFNG; IL13; IL4; IL5; NOS2; PTGS2 37.68 4
448. rosiglitazone Diabetes Mellitus, Type 2 T Via 5 genes: HNF4A; IL6; LIPC; PPARG; WFS1 36.13 4
449. rofecoxib Liver Cirrhosis, Experimental T Via 6 genes: CCL2; CYP1A2; HGF; IL1B; MMP1; PTGS2 35.32 12
450. allyl sulfide Breast Neoplasms T Via 5 genes: CYP1A1; CYP1B1; FOS; JUN; TP53 31.87 9
451. nimesulide Carcinoma, Squamous Cell T Via 4 genes: GPX1; IL8; PTGS2; VEGFA 31.52 5
452. celecoxib Carcinoma, Renal Cell T Via 4 genes: APAF1; BIRC5; PTGS2; TP53 30.58 5
453. Piroxicam Lung Neoplasms T Via 4 genes: CDKN1B; CDKN2A; MYC; TNF 29.11 8
454. Dimethyl Sulfoxide Liver Cirrhosis, Experimental T Via 5 genes: ABCB1; CCL2; CYP1A2; GSTM1; TNF 29.00 5
455. Sulfasalazine Liver Cirrhosis, Experimental T Via 4 genes: IL1B; MMP2; NOS2; TIMP1 28.16 7
456. rofecoxib Osteoarthritis T Via 3 genes: CALCA; CLU; FRZB 25.75 3
457. Sulfasalazine Breast Neoplasms T Via 4 genes: IL1B; IL8; NFKBIA; NOS2 25.58 3
458. Piroxicam Esophageal Neoplasms T Via 3 genes: CDKN2A; GSTT1; PTGS2 24.84 7
459. Sulfasalazine Colitis, Ulcerative T Via 3 genes: IL1B; IL8; RELA 24.74 2
460. troglitazone Stomach Neoplasms T Via 4 genes: CDKN1A; IL1B; PTGS2; SOD2 23.10 6
461. netoglitazone Prostatic Neoplasms T Via 3 genes: CDH1; CDKN1A; KLK3 23.09 10
462. Furosemide Heart Failure T Via 3 genes: IL6; PTH; TNFRSF1A 22.47 5
463. 4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide Liver Cirrhosis, Experimental T Via 3 genes: CCL2; MMP2; PTGS2 20.79 4
464. rofecoxib Colonic Neoplasms T Via 3 genes: IL1B; IL1RN; POSTN 20.46 3
465. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide Pancreatic Neoplasms T Via 3 genes: PTGS2; TNF; TP53 19.57 7
466. sorafenib Melanoma T Via 2 genes: BRAF; CASP8 19.11 4
467. Ampicillin Duodenal Ulcer T Via 2 genes: NOS2; PTGS2 19.06 3
468. arsenic disulfide Leukemia, Myelogenous, Chronic, BCR-ABL Positive T Via 2 genes: BCR; BIRC5 18.99 3
469. Levamisole Colorectal Neoplasms T Via 2 genes: DCC; PTGS2 18.01 5
470. Diazoxide Reperfusion Injury T Via 2 genes: IL10; TNF 17.88 2
471. rosiglitazone Metabolic Syndrome X T Via 2 genes: ADIPOQ; LEP 17.31 3
472. rofecoxib Intestinal Polyps T Via 2 genes: PTGS1; PTGS2 17.00 3
473. pioglitazone Cystic Fibrosis T Via 2 genes: SCNN1G; TGFB1 16.96 3
474. clopidogrel Cardiovascular Diseases T Via 2 genes: ICAM1; SELE 16.51 2
475. Acetylcysteine Stomach Ulcer T Via 3 genes: NOS2; PTGS2; TNF 16.38 4
476. sulforafan Adenomatous Polyposis Coli T Via 2 genes: AKT1; PTGS2 16.29 1
477. Piroxicam Neoplasms T Via 2 genes: CDKN2A; MYC 15.77 3
478. Acetylcysteine Respiratory Distress Syndrome, Adult T Via 2 genes: ALB; PLA2G4A 15.69 3
479. rofecoxib Arthritis, Experimental T Via 2 genes: CALCA; STAT3 15.59 2
480. celecoxib Adenomatous Polyposis Coli T Via 2 genes: AKT1; PTGS2 15.31 3
481. pioglitazone Diabetes Mellitus, Type 2 T Via 2 genes: INS1; PPARG 14.87 4
482. rosiglitazone Diabetes Mellitus T Via 2 genes: ADIPOQ; PTGS2 14.55 3
483. Disulfiram Neoplasm Metastasis T Via 2 genes: MMP2; MMP9 14.42 2
484. clopidogrel Neoplasm Metastasis T Via 2 genes: MMP9; TP53 14.23 3
485. celecoxib Multiple Myeloma T Via 2 genes: CCL2; CCND1 13.75 3
486. S-Adenosylmethionine Liver Cirrhosis, Experimental T Via 2 genes: AFP; TGFB1 13.54 5
487. Acetylcysteine Cystic Fibrosis T Via 2 genes: CFTR; TGFB1 13.29 5
488. Disulfiram Carcinoma, Non-Small-Cell Lung T Via 2 genes: CYP2E1; NQO1 13.28 3
489. glutamyl-Se-methylselenocysteine Breast Neoplasms T Via 2 genes: CXCL2; JUN 13.28 2
490. nimesulide Inflammation T Via 2 genes: NOS2; TNF 13.25 3
491. nimesulide Carcinoma, Hepatocellular T Via 2 genes: IL6; PTGS2 12.79 3
492. Acetylcysteine Cell Transformation, Neoplastic T Via 2 genes: MMP9; NOS2 12.73 2
493. troglitazone Diabetes Mellitus, Type 2 T Via 2 genes: IL6; PPARG 12.51 2
494. zafirlukast Asthma T Via 2 genes: CAT; TNF 12.30 54
495. Acetylcysteine Lung Diseases T Via 2 genes: TGFB1; TNF 12.05 2
496. dofetilide Arrhythmias, Cardiac T Via 1 gene: KCNH2 12.00 4
497. Methylene Blue Tauopathies T Via 1 gene: MAPT 11.93 2
498. ramatroban Rhinitis T Via 1 gene: TBXA2R 11.88 1
499. Hydrochlorothiazide Growth Disorders T Via 1 gene: AVPR2 11.74 1
500. pioglitazone Inflammation T Via 2 genes: NOS2; TNF 11.58 3
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