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GeneGene: PTPN6

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The following diseases are associated with the PTPN6 gene. This gene has either a direct association to a disease (M marker/mechanism and/or T therapeutic) or an inferred association via a curated chemical interaction.

Showing 1–182 of 182
  Disease Direct Evidence Inference Network References
1. Liver Cirrhosis, Experimental   Via 7 chemicals: Curcumin; Ethanol; pirinixic acid; Plant Extracts; valsartan; Vitamin A; Vitamin E View references.
2. Prostatic Neoplasms   Via 6 chemicals: arsenic trioxide; Curcumin; Plant Extracts; Raloxifene; sodium arsenite; Vitamin E View references.
3. Fatty Liver   Via 5 chemicals: arsenic trioxide; Curcumin; Ethanol; Plant Extracts; Raloxifene View references.
4. Multiple Myeloma   Via 5 chemicals: arsenic trioxide; Curcumin; decitabine; Raloxifene; Vitamin A View references.
5. Urinary Bladder Neoplasms   Via 5 chemicals: arsenic trioxide; Curcumin; decitabine; Raloxifene; sodium arsenite View references.
6. Carcinoma, Hepatocellular   Via 4 chemicals: arsenic trioxide; Ethanol; Plant Extracts; sodium arsenite View references.
7. Craniofacial Abnormalities   Via 4 chemicals: arsenic trioxide; Ethanol; Vitamin A; Vitamin E View references.
8. Diabetic Nephropathies   Via 4 chemicals: Curcumin; Plant Extracts; Raloxifene; valsartan View references.
9. Liver Neoplasms   Via 4 chemicals: arsenic trioxide; pirinixic acid; Plant Extracts; sodium arsenite View references.
10. Lung Neoplasms   Via 4 chemicals: arsenic trioxide; Curcumin; sodium arsenite; Vitamin E View references.
11. Ovarian Neoplasms   Via 4 chemicals: arsenic trioxide; Curcumin; decitabine; sodium arsenite View references.
12. Pancreatic Neoplasms   Via 4 chemicals: arsenic trioxide; Curcumin; decitabine; Ethanol View references.
13. Alzheimer Disease   Via 3 chemicals: Curcumin; Plant Extracts; Raloxifene View references.
14. Breast Neoplasms   Via 3 chemicals: Curcumin; decitabine; Raloxifene View references.
15. Carcinoma, Squamous Cell   Via 3 chemicals: Curcumin; decitabine; sodium arsenite View references.
16. Cardiomegaly   Via 3 chemicals: Ethanol; Plant Extracts; valsartan View references.
17. Colonic Neoplasms   Via 3 chemicals: Curcumin; decitabine; Vitamin A View references.
18. Edema   Via 3 chemicals: pirinixic acid; Plant Extracts; Raloxifene View references.
19. Inflammation   Via 3 chemicals: Curcumin; Flavonoids; Plant Extracts View references.
20. Kidney Diseases   Via 3 chemicals: sodium arsenite; valsartan; Vitamin E View references.
21. Leukemia   Via 3 chemicals: arsenic trioxide; Curcumin; decitabine View references.
22. Liver Cirrhosis   Via 3 chemicals: Ethanol; Plant Extracts; Vitamin A View references.
23. Liver Diseases   Via 3 chemicals: Curcumin; Plant Extracts; Vitamin A View references.
24. Lung Diseases   Via 3 chemicals: sodium arsenite; Vitamin A; Vitamin E View references.
25. Melanoma   Via 3 chemicals: Curcumin; decitabine; sodium arsenite View references.
26. Neural Tube Defects   Via 3 chemicals: arsenic trioxide; sodium arsenite; Vitamin A View references.
27. Stomach Ulcer   Via 3 chemicals: Curcumin; Ethanol; Plant Extracts View references.
28. Blood Coagulation Disorders   Via 2 chemicals: arsenic trioxide; pirinixic acid View references.
29. Brain Ischemia   Via 2 chemicals: Curcumin; Plant Extracts View references.
30. Cardiovascular Diseases   Via 2 chemicals: Raloxifene; valsartan View references.
31. Cleft Palate   Via 2 chemicals: Ethanol; Vitamin A View references.
32. Colitis   Via 2 chemicals: Curcumin; Selenium View references.
33. Colorectal Neoplasms   Via 2 chemicals: arsenic trioxide; decitabine View references.
34. Drug-Induced Liver Injury   Via 2 chemicals: Ethanol; Selenium View references.
35. Esophageal Neoplasms   Via 2 chemicals: arsenic trioxide; Ethanol View references.
36. Fibrosis   Via 2 chemicals: Curcumin; valsartan View references.
37. Head and Neck Neoplasms   Via 2 chemicals: Curcumin; decitabine View references.
38. Heart Defects, Congenital   Via 2 chemicals: Vitamin A; Vitamin E View references.
39. Hernia, Diaphragmatic   Via 2 chemicals: Vitamin A; Vitamin E View references.
40. Hot Flashes   Via 2 chemicals: Plant Extracts; Vitamin E View references.
41. HIV Infections   Via 2 chemicals: Plant Extracts; Vitamin A View references.
42. Hyperlipidemias   Via 2 chemicals: Fish Oils; Plant Extracts View references.
43. Hypertension   Via 2 chemicals: Raloxifene; valsartan View references.
44. Infertility, Male   Via 2 chemicals: decitabine; sodium arsenite View references.
45. Influenza, Human   Via 2 chemicals: Selenium; Vitamin E View references.
46. Intestinal Neoplasms   Via 2 chemicals: Curcumin; Plant Extracts View references.
47. Leiomyoma   Via 2 chemicals: Curcumin; Raloxifene View references.
48. Leukemia, Myeloid   Via 2 chemicals: arsenic trioxide; decitabine View references.
49. Leukemia, Myeloid, Acute   Via 2 chemicals: arsenic trioxide; decitabine View references.
50. Leukemia-Lymphoma, Adult T-Cell   Via 2 chemicals: arsenic trioxide; Curcumin View references.
51. Limb Deformities, Congenital   Via 2 chemicals: Ethanol; Vitamin A View references.
52. Liver Diseases, Alcoholic   Via 2 chemicals: Ethanol; Vitamin A View references.
53. Liver Neoplasms, Experimental   Via 2 chemicals: arsenic trioxide; Vitamin A View references.
54. Leukemia, T-Cell   Via 2 chemicals: arsenic trioxide; Curcumin View references.
55. Lymphoma   Via 2 chemicals: Curcumin; decitabine View references.
56. Memory Disorders   Via 2 chemicals: Curcumin; Ethanol View references.
57. Myelodysplastic Syndromes   Via 2 chemicals: arsenic trioxide; decitabine View references.
58. Neoplasm Invasiveness   Via 2 chemicals: arsenic trioxide; Curcumin View references.
59. Neoplasms   Via 2 chemicals: decitabine; sodium arsenite View references.
60. Obesity   Via 2 chemicals: Curcumin; Plant Extracts View references.
61. Osteoporosis   Via 2 chemicals: Curcumin; Raloxifene View references.
62. Skin Neoplasms   Via 2 chemicals: Plant Extracts; sodium arsenite View references.
63. Stomach Neoplasms   Via 2 chemicals: arsenic trioxide; decitabine View references.
64. Stroke   Via 2 chemicals: Raloxifene; Vitamin E View references.
65. Thyroid Neoplasms   Via 2 chemicals: arsenic trioxide; decitabine View references.
66. Abnormalities, Drug-Induced   Via 1 chemical: Ethanol View references.
67. Abnormalities, Multiple   Via 1 chemical: Vitamin A View references.
68. Adenocarcinoma   Via 1 chemical: arsenic trioxide View references.
69. Adrenal Gland Neoplasms   Via 1 chemical: sodium arsenite View references.
70. Adrenocortical Adenoma   Via 1 chemical: sodium arsenite View references.
71. Albuminuria   Via 1 chemical: Raloxifene View references.
72. Alcohol-Induced Disorders, Nervous System   Via 1 chemical: Ethanol View references.
73. Alcohol-Related Disorders   Via 1 chemical: Curcumin View references.
74. Anemia   Via 1 chemical: Vitamin A View references.
75. Anemia, Iron-Deficiency   Via 1 chemical: Vitamin A View references.
76. Anophthalmos   Via 1 chemical: Ethanol View references.
77. Anxiety Disorders   Via 1 chemical: Ethanol View references.
78. Arthritis, Experimental   Via 1 chemical: Plant Extracts View references.
79. Arthritis, Rheumatoid   Via 1 chemical: Curcumin View references.
80. Asthma   Via 1 chemical: Vitamin A View references.
81. Atherosclerosis   Via 1 chemical: Curcumin View references.
82. Autoimmune Diseases   Via 1 chemical: Curcumin View references.
83. Brain Injuries   Via 1 chemical: Raloxifene View references.
84. Brain Neoplasms   Via 1 chemical: Curcumin View references.
85. Bronchopulmonary Dysplasia   Via 1 chemical: Vitamin A View references.
86. Burkitt Lymphoma   Via 1 chemical: arsenic trioxide View references.
87. Burns   Via 1 chemical: Ethanol View references.
88. Carbon Tetrachloride Poisoning   Via 1 chemical: Vitamin E View references.
89. Carcinoma   Via 1 chemical: Curcumin View references.
90. Carcinoma, Papillary   Via 1 chemical: arsenic trioxide View references.
91. Carcinoma, Small Cell   Via 1 chemical: arsenic trioxide View references.
92. Carcinoma, Transitional Cell   Via 1 chemical: Raloxifene View references.
93. Cardiomyopathies   Via 1 chemical: valsartan View references.
94. Cell Transformation, Neoplastic   Via 1 chemical: sodium arsenite View references.
95. Child Nutrition Disorders   Via 1 chemical: Vitamin A View references.
96. Cholestasis   Via 1 chemical: Vitamin A View references.
97. Cleft Lip   Via 1 chemical: Ethanol View references.
98. Cognition Disorders   Via 1 chemical: Raloxifene View references.
99. Corneal Neovascularization   Via 1 chemical: Curcumin View references.
100. Coronary Artery Disease   Via 1 chemical: valsartan View references.
101. Coronary Restenosis   Via 1 chemical: arsenic trioxide View references.
102. Coxsackievirus Infections   Via 1 chemical: valsartan View references.
103. Death, Sudden, Cardiac   Via 1 chemical: arsenic trioxide View references.
104. Depressive Disorder, Major   Via 1 chemical: Raloxifene View references.
105. Diabetes Mellitus, Type 1   Via 1 chemical: Vitamin A View references.
106. Diabetes Mellitus, Type 2   Via 1 chemical: Curcumin View references.
107. Diabetes Mellitus, Experimental   Via 1 chemical: valsartan View references.
108. Dry Eye Syndromes   Via 1 chemical: Vitamin A View references.
109. Duodenal Ulcer   Via 1 chemical: Curcumin View references.
110. Ectromelia   Via 1 chemical: Vitamin A View references.
111. Encephalomyelitis, Autoimmune, Experimental   Via 1 chemical: Raloxifene View references.
112. Endocrine Gland Neoplasms   Via 1 chemical: decitabine View references.
113. Endomyocardial Fibrosis   Via 1 chemical: Plant Extracts View references.
114. Fatty Liver, Alcoholic   Via 1 chemical: Ethanol View references.
115. Fetal Alcohol Syndrome   Via 1 chemical: Ethanol View references.
116. Fetal Resorption   Via 1 chemical: Vitamin A View references.
117. Gallbladder Neoplasms   Via 1 chemical: arsenic trioxide View references.
118. Gastrointestinal Neoplasms   Via 1 chemical: Curcumin View references.
119. Genital Neoplasms, Female   Via 1 chemical: sodium arsenite View references.
120. Glioblastoma   Via 1 chemical: Curcumin View references.
121. Glomerulonephritis, Membranoproliferative   Via 1 chemical: valsartan View references.
122. Heart Diseases   Via 1 chemical: Raloxifene View references.
123. Heart Failure   Via 1 chemical: Selenium View references.
124. Hereditary Sensory and Motor Neuropathy   Via 1 chemical: Curcumin View references.
125. Herpes Simplex   Via 1 chemical: Plant Extracts View references.
126. Hodgkin Disease   Via 1 chemical: sodium arsenite View references.
127. HIV Seropositivity   Via 1 chemical: Vitamin A View references.
128. Hyperalgesia   Via 1 chemical: Ethanol View references.
129. Hypercholesterolemia   Via 1 chemical: Curcumin View references.
130. Hyperhomocysteinemia   Via 1 chemical: Plant Extracts View references.
131. Hypersensitivity, Delayed   Via 1 chemical: Fish Oils View references.
132. Hypertension, Malignant   Via 1 chemical: valsartan View references.
133. Hypervitaminosis A   Via 1 chemical: Vitamin A View references.
134. Inflammatory Bowel Diseases   Via 1 chemical: Curcumin View references.
135. Jaw Abnormalities   Via 1 chemical: Ethanol View references.
136. Kidney Failure, Chronic   Via 1 chemical: Selenium View references.
137. Learning Disorders   Via 1 chemical: Ethanol View references.
138. Leukemia, Myelogenous, Chronic, BCR-ABL Positive   Via 1 chemical: arsenic trioxide View references.
139. Leukemia, Myelomonocytic, Chronic   Via 1 chemical: decitabine View references.
140. Liver Cirrhosis, Alcoholic   Via 1 chemical: Ethanol View references.
141. Long QT Syndrome   Via 1 chemical: arsenic trioxide View references.
142. Lymphoma, T-Cell   Via 1 chemical: Curcumin View references.
143. Mammary Neoplasms, Experimental   Via 1 chemical: Selenium View references.
144. Mesothelioma   Via 1 chemical: Selenium View references.
145. Mixed Tumor, Mullerian   Via 1 chemical: Raloxifene View references.
146. Muscular Atrophy, Spinal   Via 1 chemical: Curcumin View references.
147. Mycosis Fungoides   Via 1 chemical: arsenic trioxide View references.
148. Leukemia, Promyelocytic, Acute   Via 1 chemical: arsenic trioxide View references.
149. Leukemia, Monocytic, Acute   Via 1 chemical: arsenic trioxide View references.
150. Myxoma   Via 1 chemical: Raloxifene View references.
151. Neoplasms, Experimental   Via 1 chemical: sodium arsenite View references.
152. Neoplasms, Hormone-Dependent   Via 1 chemical: Curcumin View references.
153. Nervous System Neoplasms   Via 1 chemical: Curcumin View references.
154. Neurobehavioral Manifestations   Via 1 chemical: Plant Extracts View references.
155. Carcinoma, Non-Small-Cell Lung   Via 1 chemical: Curcumin View references.
156. Osteoporosis, Postmenopausal   Via 1 chemical: Raloxifene View references.
157. Papilloma   Via 1 chemical: Plant Extracts View references.
158. Paraganglioma   Via 1 chemical: arsenic trioxide View references.
159. Plasmacytoma   Via 1 chemical: Selenium View references.
160. Primary Myelofibrosis   Via 1 chemical: decitabine View references.
161. Proteinuria   Via 1 chemical: valsartan View references.
162. Pulmonary Emphysema   Via 1 chemical: Curcumin View references.
163. Pulmonary Fibrosis   Via 1 chemical: valsartan View references.
164. Purpura   Via 1 chemical: Raloxifene View references.
165. Respiratory Distress Syndrome, Adult   Via 1 chemical: Curcumin View references.
166. Respiratory Distress Syndrome, Newborn   Via 1 chemical: Vitamin A View references.
167. Rhabdomyosarcoma   Via 1 chemical: decitabine View references.
168. Sarcoma   Via 1 chemical: Curcumin View references.
169. Sarcoma, Ewing's   Via 1 chemical: arsenic trioxide View references.
170. Seizures   Via 1 chemical: Ethanol View references.
171. Sepsis   Via 1 chemical: Curcumin View references.
172. Spinal Dysraphism   Via 1 chemical: sodium arsenite View references.
173. Substance Withdrawal Syndrome   Via 1 chemical: Ethanol View references.
174. Temporomandibular Joint Disorders   Via 1 chemical: Plant Extracts View references.
175. Torsades de Pointes   Via 1 chemical: arsenic trioxide View references.
176. Urogenital Neoplasms   Via 1 chemical: Curcumin View references.
177. Uterine Cervical Neoplasms   Via 1 chemical: sodium arsenite View references.
178. Uveal Neoplasms   Via 1 chemical: decitabine View references.
179. Vascular Diseases   Via 1 chemical: sodium arsenite View references.
180. Venous Thromboembolism   Via 1 chemical: Raloxifene View references.
181. Vitamin A Deficiency   Via 1 chemical: Vitamin A View references.
182. Vulvar Neoplasms   Via 1 chemical: Raloxifene View references.
Showing 1–182 of 182
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