ChemComps presents the chemicals with the most comparable sets of interacting genes as the page's subject chemical.
By default, this page shows Comps calculated using all 70 chemical–gene interaction types. You can perform a more focused similarity calculation by choosing a specific interaction type and one or more degrees to limit the interactions considered.
Similarity (or comparability) is measured by the
Jaccard index—the size of the intersection
of interacting genes for chemical A and chemical B divided by the size of the union of those genes:
The chemicals with comparable interacting gene sets as the page's subject chemical.
You may view the common interacting genes between the page's subject chemical and a chemical of interest by clicking a link in this column. This link will take you to results generated using the VennViewer tool.
The common interacting genes are also included in the downloadable files.
Save these data into a comma-separated values (CSV), Excel, XML, or tab-separated values (TSV) file by clicking a Download link at the bottom of the table.
The XGMML file can be viewed using Cytoscape, an open-source pathway visualization application: