CTD curates specific chemical–gene and protein interactions in vertebrates and invertebrates from the published literature. This full report presents the following information about manually curated chemical–gene and protein interactions:

• The interacting chemical.
• The organism in which an interaction was reported.
• The description of the interaction.
• The reference reporting the interaction.

You may sort these data by clicking on the column headings.

You may save these data into a comma-separated values (CSV) file, XML file or tab-separated values (TSV) file by clicking on the corresponding links at the bottom of the table. CSV and TSV files may be opened using Microsoft Excel.

Most interactions are binary and involve one chemical and one gene or protein (e.g., “3-methylquercetin results in decreased activity of ABCC1 protein”). Brackets represent nested events in more complex interactions (e.g., “[3,4,5,3',4'-pentachlorobiphenyl binds to AHR protein] which results in increased expression of ABCC3 mRNA”).