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Help: GeneComps

GeneComps presents the genes with the most comparable sets of interacting chemicals as the page's subject gene.

Filter by interaction type

By default, this page shows Comps calculated using all 70 chemical–gene interaction types. You can perform a more focused similarity calculation by choosing a specific interaction type and one or more degrees to limit the interactions considered.

Similarity Index

Similarity (or comparability) is measured by the Jaccard index—the size of the intersection of interacting chemicals for gene A and gene B divided by the size of the union of those chemicals:
Jaccard Index formula: A∩B / A∪B


The genes with comparable interacting chemical sets as the page's subject gene.

Common Interacting Chemicals

View the common interacting chemicals between the page's subject gene and a gene of interest by clicking a link in this column. This link will take you to results generated using the VennViewer tool.

The common interacting chemicals are also included in the downloadable files.


Save these data into a comma-separated values (CSV), Excel, XML, or tab-separated values (TSV) file by clicking a Download link at the bottom of the table.