The MyGeneVenn tool allows you to generate a Venn diagram that will identify logical relationships between your genes of interest and gene sets in CTD that are associated with up to two chemicals or diseases.
For example, you may compare significantly differentially expressed genes from a microarray experiment involving a chemical exposure or disease state to CTD genes associated with these or other chemicals or diseases in order to validate or supplement your experimental data. See, e.g., Mattingly CJ, et al. (2009). [PubMed:19590694]
Enter or paste the NCBI official symbols or accession IDs (“ID:#####”) for your genes of interest (e.g., significantly differentially expressed genes from a microarray experiment involving a chemical exposure or disease state).
Input terms may be separated by returns or tabs.
Specify the name by which your custom data set should be labelled in the Venn diagram.
Select this option to compare your input gene list to genes having curated interactions with one or two specified chemicals.
You may specify chemicals by MeSH® name, synonym or accession ID (“ID:#####”), or by CAS RN.
Select this option to compare your input gene list to genes with direct relationships to one or two specified diseases. Direct gene–disease relationships are established by both CTD and OMIM curation.
You may specify diseases by MeSH or OMIM name, synonym or accession ID (“ID:#####”).
Select this option to compare your input gene list to genes with inferred relationships to one or two specified diseases. Inferred gene–disease relationships are established via CTD–curated chemical–gene interactions (e.g., Chemical A is associated with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a direct relationship with Disease B).
You may specify diseases by MeSH or OMIM name, synonym or accession ID (“ID:#####”).
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