The MyGeneVenn tool allows you to generate a Venn diagram that will identify logical relationships between your genes of interest and gene sets in CTD that are associated with up to two chemicals or diseases.
For example, you may compare significantly differentially expressed genes from a microarray experiment involving a chemical exposure or disease state to CTD genes associated with these or other chemicals or diseases in order to validate or supplement your experimental data. See, e.g., Mattingly CJ, et al. (2009). PMID:19590694
Enter or paste the NCBI (Entrez Gene) symbols or accession IDs (“GENE:…”) for your genes of interest (e.g., significantly differentially expressed genes from a microarray experiment involving a chemical exposure or disease state).
You may separate terms by returns, tabs, or vertical bars (|).
Specify the name (up to 200 characters) by which your gene set should be labelled in the Venn diagram.
Select this option to compare your input gene list to genes having curated interactions with one or two specified chemicals.
You may specify chemicals by MeSH® name, synonym, or accession ID (“MESH:…”), or by CAS RN. To limit your search to official names, use the “name:” prefix.
Select this option to compare your input gene list to genes with curated associations to one or two specified diseases. Curated gene–disease associations are established by both CTD and OMIM curation.
Select this option to compare your input gene list to genes with inferred associations to one or two specified diseases. Inferred gene–disease associations are established via CTD–curated chemical–gene interactions (e.g., Chemical A is associated with Disease B because Chemical A has a curated interaction with Gene C, and Gene C has a curated association with Disease B).