Chemical: Tretinoin
Name
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Tretinoin |
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CAS Type 1 Name
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Retinoic acid |
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Equivalent Terms
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Acid, Retinoic; Acid, Vitamin A; Acid, all-trans-Retinoic; Acid, beta-all-trans-Retinoic; Acid, trans-Retinoic; Potassium Salt, Tretinoin; Retin A; Retin-A; Retinoic Acid; Salt, Tretinoin Potassium; Salt, Tretinoin Sodium; Salt, Tretinoin Zinc; Sodium Salt, Tretinoin; Tretinoin Potassium Salt; Tretinoin Sodium Salt; Tretinoin Zinc Salt; Vesanoid; Vitamin A Acid; Zinc Salt, Tretinoin; all trans Retinoic Acid; all-trans-Retinoic Acid; beta all trans Retinoic Acid; beta-all-trans-Retinoic Acid; trans Retinoic Acid; trans-Retinoic Acid |
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CAS Registry Number
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302-79-4 |
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Definition
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An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). |
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Chemical Drawing
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MeSH®
ID
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D014212 |
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Top Interacting Genes
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Hierarchies 
>
Hydrocarbons
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Hydrocarbons, Acyclic
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Alkenes
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Polyenes
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Carotenoids
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Retinoids
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Vitamin A
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Hydrocarbons
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Hydrocarbons, Cyclic
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Hydrocarbons, Alicyclic
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Cycloparaffins
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Cyclohexanes
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Cyclohexenes
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Carotenoids
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Retinoids
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Vitamin A
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Hydrocarbons
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Terpenes
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Carotenoids
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Retinoids
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Vitamin A
= Related chemicals.
= Related genes.
= Related diseases.
= References.
= Is curated.
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